Abstract: Described is a novel epicutaneous test plaster useful for the application of test substances for direct and continuous contact with the skin of a human patient. The plaster comprises a support lattice with a flexible carrier lattice adhered thereto, the combination forming a series of test chambers capable of receiving test substances for application to the skin.

Abstract: An implantable microphone for a middle ear prosthesis, includes an attachment system for fixing to a fixation bone close to an individual's middle ear; a cylindrical holding sheath, the sheath to be fixed to the fixation bone by the attachment system and having a suitable shape for extending from the fixation bone towards the ear ossicles of the individual; a coupler including a rod and an end piece of a suitable shape for bringing into contact with a point of the ear ossicles of the individual in a reversible manner; a sensor for converting a mechanical signal into an electrical signal, the sensor being secured to the coupler, supported by the cylindrical holding sheath and placed substantially in the extension of the axis of the cylinder; and a translation system for translation of the coupler along the axis of the cylinder, the translation system being housed in the sheath.

Abstract: The invention provides a shape memory spacer fabric composite, being a spacer fabric coated with a shape memory polymer layer, wherein the spacer fabric comprises a first outer layer, a second outer layer and an intermediate spacing layer connecting the first outer layer and the second outer layer; the shape memory polymer layer is made from at least one block or random copolymer selected from the group consisting of the following: polyesters, polyurethanes, polyamides, polyols; the copolymer has at least one phase transition temperature in a range of 40˜80° C.

Abstract: The invention relates to a method for the manufacturing of a carrying device, a carrying device, a system for detection and a method for detection of at least one physical parameter and/or chemical composition. A method for the manufacturing of a carrying device for reception of at least one sensor is presented, in which a receiving body with a surface to be coated is provided. In the receiving body, a space is provided which is open on the side of this surface. A second body with a sealing surface is provided. This sealing surface is positioned in such a manner that the surface to be coated of the receiving body is sealed by the second body at least in the circumference of the space in the receiving body. A formable or moldable filling material is provided in the space in such a manner that the filling material forms a surface shaped complementary to the sealing surface of the second body, closing the space.

Abstract: A device, including an implantable microphone, including a transducer, and a chamber in which a gas is located such that vibrations originating external to the microphone based on sound are effectively transmitted therethrough, wherein the transducer is in effective vibration communication with the gas, wherein the transducer is configured to convert the vibrations traveling via the gas to an electrical signal, the chamber and the transducer correspond to a microphone system, wherein the chamber corresponds to a front volume of the microphone system, and the transducer includes a back volume corresponding to the back volume of the microphone system, and the implantable microphone is configured to enable pressure adjustment of the front and/or back volume in real time.

Abstract: The present disclosure discloses a radiation treatment device and pertains to the field of medical appliance technologies. The radiation treatment device includes a radiotherapy unit and an imaging unit. The radiotherapy unit is configured to emit a treatment beam to a to-be-treated region in a patient, wherein the to-be-treated region in the patient is located outside the radiotherapy unit. The imaging unit is arranged adjacent to the radiotherapy unit and is configured to emit an imaging beam to the to-be-treated region in the patient. Without moving the to-be-treated region in a patient, the radiotherapy unit may emit the treatment beam to the to-be-treated region in the patient according to the treatment plan worked out to execute the radiation treatment, such that the accuracy of the radiation treatment is improved.

Abstract: Embodiments of the present disclosure are directed to treatment planning systems for a radiotherapy apparatus. In one implementation, a treatment planning system may include a computational processor configured to apply a set of instructions to an input data set. The input data set may include a three-dimensional dose distribution for delivery by the radiotherapy apparatus to a volume to be irradiated, a three-dimensional volume image characterizing tissue types within the volume to be irradiated, and a set of apparatus parameters which characterize the radiotherapy apparatus. The set of instructions may include a computational process configured to output a treatment plan for delivery of the dose distribution by the radiotherapy apparatus, by optimising a function representing a time-dependent response of the tissue types to an applied radiation.

Abstract: A source guide apparatus for brachytherapy application, wherein the source guide apparatus is provided with a source capsule, a guidewire for moving the source capsule through a catheter, a mechanical connection between the guidewire and the source capsule, wherein the source guide apparatus is provided with a sleeve which is attached on the capsule, wherein the sleeve envelops at least a part of the mechanical connection.

Abstract: A needle employs a three-stair-stepped structure including a front-end small diameter part, an intermediate part, and a large diameter part. The front-end small diameter part and the intermediate part are in fluid communication with each other by a first tapered part, and the intermediate part and the large diameter part are in fluid communication with each other by a second tapered part. The internal diameter of the front-end small diameter part is made so as to be equal to or greater than 0.35 mm based on the allowable deformation level of a cumulus oocyte complex, the outer diameter is made so as to be equal to or smaller than 0.7 mm based on the size of a small follicle, and the inclination angle of the inclined acicular end, and the length is made so as to be 10-25 mm based on the size of a dominant follicle.

Abstract: A proton therapy system based on a compact superconducting cyclotron, including: a superconducting cyclotron system, an energy selection system, a beam transport system, a fixed therapy room subsystem and a rotating frame therapy subsystem; a fixed-energy proton beam extracted from a superconducting cyclotron of the superconducting cyclotron system is adjusted into a continuous and adjustable proton beam of 70 MeV to 200 MeV by the energy selection system, thus realizing a longitudinal adjustment for a proton range during treating a tumor, and the continuous and adjustable proton beam is respectively transmitted to the fixed therapy room subsystem and the rotating frame therapy subsystem by the beam transport system. The cooperative control of the superconducting cyclotron system, the energy selection system, the beam transport system and the therapy head realizes the transverse expansion of proton beams, thus realizing intensity modulated radiation therapy for the tumor.

Abstract: Methods and devices for minimally-invasive delivery of radiation to the eye (such as the posterior portion of the eye) including cannula systems with multiple treatment positions and/or multiple channels in the distal tip of the cannula systems. The channels can accommodate emanating sources and exposing a target at various treatment positions. The emanating sources may be annulus-shaped.

Abstract: A method and apparatus comprising to utilize local data to improve sleep is described. The method includes identifying local data relevant to a user's sleep quality, evaluating a user's sleep environment and sleep settings, and changing the user's sleep environment and/or sleep settings based on the local data.

Abstract: In radiation therapy, treatment objectives applicable to different identified structures in a patient's body (e.g., a target structure and an organ at risk (OAR)) may conflict due to overlap between the structures. Automated systems and methods can detect and resolve such conflicts. For example, a set of modified regions that do not overlap with each other can be defined, and a modified treatment objective for each modified region can be determined based on the original treatment objectives. The modified regions and modified treatment objectives can be used in treatment planning processes.

Abstract: An implant or sling sheath system having an overlapping sheath material is provided. The sheath can include two telescoping or overlapping sections. The overlapping sections can include at least one release feature to eliminate or reduce sticking of the overlapping sections together during use.

Abstract: A cardiac support device includes a jacket and elastic attachment structure for self-securing the jacket to a heart. The attachment structures can include undulating metal and polymer elements, a silicone band and elastomeric filaments on a base end of the jacket.

Abstract: A sterile liquid transfer assembly for use with a catheter assembly. The sterile liquid transfer assembly includes a protective element and a carrier element. The protective element includes a pliable, hollow protective valve member having a pivot cutaway portion. A tubular member of the protective element depends from a surface of the hollow protective valve member. The protective valve member is configured to define a stop for limiting the insertion of the tubular member in a canal of a patient.

Abstract: Provided are a method, a device, a system, and a program for evaluating similarity of brain activity with respect to an object to be evaluated, using data obtained by a simple measurement of brain waves. Brain wave data related to cognitive processing with respect to a plurality of sensory stimuli are dimensionally compressed, and a distribution of the object to be evaluated is displayed on a two-dimensional plane or three-dimensionally. In this way, similarity of brain information with respect to the plurality of sensory stimuli is evaluated, and the similarity is visualized. The brain wave data related to the cognitive processing include brain wave data upon selection of a stimulus as a target, and brain wave data caused by a non-target stimulus event.

Abstract: Provided herein is a multichannel Transcranial Magnetic Stimulation (mTMS) coil device with two or more overlapping coil windings within a casing. The mTMS coil device is capable of adjusting parameters of the stimulation of magnetic and induced electric fields through the selective control of the multiple coil windings within the mTMS coil device. Additionally, provided are methods of operation including navigated TMS for adjusting parameters such as location, direction and/or orientation of magnetic and induced electric fields from mTMS coil devices.

Abstract: The invention provides a therapy method for glioblastoma multiforme (GBM). The therapy method uses a low-dose radiation to realize GBM tumor cell-targeted radiotherapy via sequentially administration of radiation enhancer-incorporated nanocarriers, 5-aminolevulinic acid, therapeutic ultrasound and therapeutic radiation.

Abstract: Disclosed are devices, methods, and systems for helping to prevent (or preventing) or treat brain and/or body disorders. Embodiments of the invention have utility for enhancing cognitive function during aging. The invention utilizes electromagnetic stimulation (EMS) that can provide a range of EMS parameters and modalities. The EMS may be utilized in conjunction with physiologic sensors that can provide feedback for possible EMS modifications.