Abstract: Provided are a radiation treatment planning system and a radiation treatment system that are capable of achieving time shortening and labor saving of treatment planning making when a radiation treatment is planned. A predicted DVH calculation portion 4034 of an arithmetic processing device 403 in a radiation treatment planning system 400 anisotropically enlarges a target region 501 in an irradiated body image which is input to the radiation treatment planning system 400, and calculates an overlap volume OV with an organ-at-risk region 502 per the number of times of enlargement. A DVH (Dose Volume Histogram) is predicted from a volume of the calculated OV, and a dose histogram in the OV per the number of times of enlargement which is calculated from a past treatment planning data group, and is displayed on a display device 401.

Abstract: Neural stimulator systems with an external magnetic coil to produce changing magnetic fields is applied outside the body, in conjunction with one or more tiny injectable objects that concentrates the induced electric field to a highly-targeted location. These systems include a driver circuit for the magnetic coil that allows for high voltage and fast pulses in the coil, while requiring low-voltage power supply that may be powered by a wearable or portable external device, along with the coil and driver circuit.

Abstract: An immunomagnetic nanocapsule includes a core, a shell and an outer layer. The shell is formed by a complex, and the complex is fabricated by a combination of fucoidan, oxidized dextran, and a plurality of superparamagnetic iron oxide nanoparticles via a hydrophobic interaction. The core is encapsulated in the shell. The outer layer includes at least one antibody immobilized to outside of the shell to form the outer layer, wherein the antibody is an immune checkpoint inhibitor and/or a T cell expansion antibody.

Abstract: A device is provided for the stimulation of neurons that includes a non-invasive stimulation unit to generate stimuli in multiple stimulation channels, where the stimulation unit stimulates a neuron population in the brain and/or spinal cord of a patient in different locations for each of the stimulation channels. Moreover, the device includes a control unit that controls the stimulation unit to generate repetitive bursts in each of the stimulation channels, where each of the bursts includes multiple stimuli and is designed so that they do not reset the phase of the neuronal activity of the respective stimulated neurons.

Abstract: A collapsible incubator for an infant, the collapsible incubator comprising: a flexible housing for containing the infant, the flexible housing being configurable between an expanded condition and a collapsed condition; a door within the flexible housing for infant access; a first end portion secured to a first end of the flexible housing; a second end portion secured to a second end of the flexible housing, said second end portion being configured to be substantially opposite said first end portion; and, at least one fastening means configured to releasably secure the first end portion to the second end portion when in the collapsed condition, whereby the first end portion and the second end portion are configured, in use, to support the flexible housing in the expanded condition, and to substantially contain the flexible housing therebetween in the collapsed condition.

Abstract: Apparatuses and methods described herein relate to treating cancerous tumors using radiation therapy and chemotherapy. In some embodiments, a method of treatment includes administering radiation therapy targeting a tumor, isolating a segment of a vessel proximate to the tumor, and administering a dose of a chemotherapeutic agent to the segment of the vessel. The method can further include waiting a period of time after administering the radiation therapy before administering the dose of the chemotherapeutic agent. In some embodiments, a catheter device including first and second occluding elements can be used to isolate the segment of the vessel.

Abstract: In one embodiment, an implant includes a support member configured to be placed within a body of a patient and provide support to a portion of the body of the patient, a tether coupled to an end portion of the support member; and an anchor configured to be disposed within a tissue of the body of the patient to help retain the implant in place within the body of the patient. The tether is coupled to the anchor such that the tether may move with respect to the anchor in a first direction but is retrained from moving in a second direction.

Abstract: The present invention relates to the use of an oxytocin receptor antagonist in females undergoing embryo transfer as part of an assisted reproductive technology. In particular, methods are provided for increasing ongoing implantation rate, increasing ongoing pregnancy rate, increasing clinical pregnancy rate, and/or increasing live birth rate in a female subject undergoing embryo transfer. Specifically, the antagonists are released in the luteal phase when the endometrium is receptive for embryo implantation and/or when the embryo has reached the blastocyst-stage.

Abstract: Devices and methods for detecting joint motion of a user. In particular embodiments, devices may comprise a deflectable beam coupled to a user via adhesive pads located between the neck and shoulder of the use. Audio and haptic feedback can be provided to the user when the deflectable beam deflects due to motion of the joint.

Abstract: A system for affecting, augmenting, or enhancing erection of the penis includes an elastomeric sleeve designed to comfortably and securely encircle the base of the penis. The sleeve is provided with a pair of inflatable chambers, a dorsal insert, and a ventral insert which are configured to apply focal pressure on the dorsal penile veins, while avoiding undue constriction of the corpora cavernosa or compression of the urethra, dorsal penile arteries, or nerves. The system includes fluid transfer apparatus having a reservoir for pressurized fluid, a pump, and valves for controlling the flow of fluid to the inflatable chambers. The system also includes an inflatable sealing apparatus which, when used in combination with a conventional vacuum erection tube, forms an airtight seal between the sleeve and the open end of the inflatable sealing member.

Abstract: The device for positioning a magnetic coil for transcranial magnetic stimulation in relation to the head of a patient includes a head unit with a support for the patient's head and a positioning unit, which is connected to the support, with a coil seat for holding the magnetic coil. The device also includes a fixedly installed holding arm holding the head unit. A reversibly movable connection is provided between the head unit and the holding arm, and configured such that a change of a force, which is applied onto the support by the head of the patient, leads to a relative movement between the head unit and the holding arm through the movable connection.

Abstract: A biometric detection module including a light source module, a detection region and a control module is provided. The light source module is configured to emit green light, red light and IR light in a time division manner to illuminate a skin surface. The detection region is configured to detect penetration light emitted from the light source module for illuminating the skin surface and passing through body tissues to correspondingly generate a green light signal, a red light signal and an IR light signal. The control module is configured to determine a filtering parameter according to the green light signal to accordingly filter the red light signal and the IR light signal, and calculate a biometric characteristic according to at least one of the green light signal, a filtered red light signal and a filtered IR light signal.

Abstract: Improved methods and apparatus to secure a urethral sling to pubic bone in a sub-urethral location to support the urethra and alleviate incontinence are disclosed. The urethral sling is preferably formed of a flexible sheet material extending between opposed first and second sling ends and bounded by opposed first and second sling sides. The urethral sling is selectively tensioned in a central portion intermediate the first and second sling ends and/or in one or both of end portions bracketing the central portion. In one embodiment, pre-positioned plicating lines in the central portion are selectively drawn and tied to slacken the central portion and tension the end portions. In further embodiments, bone anchor lines passed through locations displaced from the sling ends are drawn and fixed to tension the central portion between the displaced locations and slacken the end portions.

Abstract: A device for non-invasive treatment of a disorder in a patient comprising a magnetic portion having a first side and a second side, a first metal portion having a first end and a second end, and a second metal portion configured for hand holding and having a first side and a second side, wherein second side of the second metal portion: (i) is coupled to the first side of the magnetic portion; and (ii) has a surface area that is less than the surface area of the first side of the magnetic portion; and wherein the first metal portion is coupled to the second side of the magnetic portion. The first metal portion is optionally fitted with a head. The disclosure further relates to non-invasive methods for treating a disorder in a patient, wherein said methods use said magnetic device.

Abstract: The present technology relates to an information processing device and an information processing method capable of facilitating fixed-point observation on skin condition. The information processing device acquires an image that shows a predetermined feature point of a user who is a measurer of skin condition, and a measurement portion of skin condition, and analyzes the image, and then recognizes a position of the feature point. Furthermore, information indicating the measurement portion is displayed at a predetermined position on the image while setting, as a reference, the recognized position of the feature point. The present technology is applicable to information processing devices such as a tablet terminal, a smartphone, and a personal computer.

Abstract: A method of evaluating the robustness of a radiotherapy treatment plan for ion based radiotherapy, comprises the steps of: obtaining information related to the incident energy of ions that will stop in each voxel of the treatment volume; calculating a quantity value representative of the incident energy of these ions; and using the quantity values calculated for the first and second portion as a measure of the quality of the radiotherapy treatment plan, in particular its robustness. The information may include the mean incident energy for all ions, and/or an indication of the distribution of the energy values for all the ions.

Abstract: [Object] To measure a form of light scattering in a body more simply. [Solution] A measurement device according to the present disclosure includes: a light source configured to emit at least one kind of measurement light belonging to a predetermined wavelength band toward a measurement region formed by at least a part of a living body; a detection unit configured such that a plurality of sensors are arranged regularly in a predetermined disposition and the measurement light emitted from the light source and transmitted through the living body is detected by the plurality of sensors; and an analysis unit configured to analyze at least one of rectilinearity of the measurement light in the living body and an optical distance from the light source using a detection result of the measurement light detected by the detection unit.

Abstract: An R-wave of a heartbeat signal accompanied by periodic fluctuation is detected to obtain the average value of an RR interval. Further, a waveform of a heart sound signal, which periodically fluctuates in synchronization with the heartbeat signal, is forcibly repositioned at an interval equivalent to the average value of the RR interval. After performing reposition, noise is removed by using orthogonal transformation and orthogonal inverse transformation, so that the position of obtained waveform is restored to its original position.

Abstract: Disclosed herein is a probe 1 for measuring a lip closing force, the probe including: a hollow balloon 10 configured to be disposed between an upper lip 50 and lower lip 51 of a subject, and crushed and deformed by the lip closing force, and a base 20 which is connected to a pressure measurement device 100 for measuring an internal pressure of the balloon 10. The balloon 10 is provided with a fixable portion 13 configured to be sandwiched between teeth 52 and 53 or gums of the subject.

Abstract: A method and apparatus is presented for optimizing a treatment plan for irradiation therapy. The method includes defining a single objective function based on a plurality of objective functions that are each associated with a plurality of tissue types within a subject, upper and lower bounds for each objective function and a plurality of apertures. The method also includes determining a radiation dose delivered to voxels of each tissue type based on minimizing the single objective function based on the plurality of apertures with initial values at each angle. The method also includes delivering a beam of radiation with controlled intensity and beam cross-sectional shape at each angle based on the plurality of apertures.