Patents Examined by Catherine M Voorhees
  • Patent number: 11576617
    Abstract: This disclosure is directed towards detecting artifacts in an ECG signal. An ECG system may include multiple sensors which can sense an ECG signal when attached to a patient. Bipolar leads connect the sensors, and provide the ECG signal from the sensors to a computing device. The computing device receives respective signals from the bipolar leads, where the respective signals are indicative of the ECG signal. The computing device identifies, based on the respective signals, a potential artifact corresponding to a subset of the plurality of bipolar leads. The computing device determines that each lead of the subset of the plurality of bipolar leads is connected to a common sensor. The computing device may use signals originating from a remainder of the bipolar leads (e.g., the bipolar leads that are not connected to the sensor(s) where the artifact is detected) to detect a condition of the patient.
    Type: Grant
    Filed: August 28, 2020
    Date of Patent: February 14, 2023
    Assignee: Welch Allyn, Inc.
    Inventors: David W Mortara, Patrick J. Noffke, Reyhaneh Sepehr
  • Patent number: 11576721
    Abstract: Disclosed herein are systems and methods for locating and identifying nerves innervating the wall of arteries such as the renal artery. The present invention identifies areas on vessel walls that are innervated with nerves; provides indication on whether energy is delivered accurately to a targeted nerve; and provides immediate post-procedural assessment of the effect of energy delivered to the nerve. The methods includes evaluating a change in physiological parameters after energy is delivered to an arterial wall; and determining the type of nerve that the energy was directed to (sympathetic or parasympathetic or none) based on the evaluated results. The system includes at least a device for delivering energy to the wall of blood vessel; sensors for detecting physiological signals from a subject; and indicators to display results obtained using said method. Also provided are catheters for performing the mapping and ablating functions.
    Type: Grant
    Filed: July 27, 2020
    Date of Patent: February 14, 2023
    Assignee: SYMAP MEDICAL (SUZHOU), LIMITED
    Inventor: Jie Wang
  • Patent number: 11576606
    Abstract: An example device for detecting one or more parameters of a cardiac signal is disclosed herein. The device includes one or more electrodes and sensing circuitry configured to sense a cardiac signal via the one or more electrodes. The device further includes processing circuitry configured to determine an R-wave of the cardiac signal and determine whether the R-wave is noisy. Based on the R-wave being noisy, the processing circuitry is configured to determine whether the cardiac signal around a determined T-wave is noisy. Based on the cardiac signal around the determined T-wave not being noisy, the processing circuitry is configured to determine a QT interval or a corrected QT interval based on the determined T-wave and the determined R-wave.
    Type: Grant
    Filed: March 22, 2021
    Date of Patent: February 14, 2023
    Assignee: Medtronic, Inc.
    Inventors: Gautham Rajagopal, Shantanu Sarkar
  • Patent number: 11571586
    Abstract: Provided are conformable light delivery devices for increasing light penetration depth and related methods. The device may comprise a microarray of tissue penetrating members, each member having a distal end and a proximal end, wherein the tissue penetrating members are at least partially optically transparent to provide optical transmission through a surface that extends between the distal and proximal ends of each tissue penetrating member and a substrate that supports the tissue penetrating members, wherein the substrate is optionally a flexible substrate.
    Type: Grant
    Filed: May 17, 2019
    Date of Patent: February 7, 2023
    Assignee: NORTHWESTERN UNIVERSITY
    Inventors: Shuai Xu, Chenkai Xu, Hao Zhang, Hangbo Zhao, John A. Rogers
  • Patent number: 11559355
    Abstract: A virtual or augmented reality system is disclosed which is capable of both (i) evaluating prospective implantable neurostimulator patient candidates, and (ii) determining optimal stimulation settings for already-implanted neurostimulation patients. Physiological sensors are included with the system to provide objective measurements relevant to a patient's symptoms, such as pain in a Spinal Cord Stimulation (SCS) system. Such objective measurements are determined during the presentation of various virtual or augmented environments, and can be useful to determining which patients are suitable candidates to consider for implantation. Stimulation settings for already-implanted patients may be adjusted while presenting a virtual or augmented environment to the patient, with objective measurements being determined for each stimulation setting. Such objective measurements can then be used to determine optimal stimulation settings for the patient.
    Type: Grant
    Filed: June 17, 2019
    Date of Patent: January 24, 2023
    Assignee: Boston Scientific Neuromodulation Corporation
    Inventors: Elizabeth M. Annoni, Bryan A. Clark, Dennis Zottola, Kyle H. Srivastava, Jonathan B. Shute
  • Patent number: 11559241
    Abstract: Computer implemented methods and systems are provided that comprise, under control of one or more processors of a medical device, where the one or more processors are configured with specific executable instructions. The methods and systems obtain motion data indicative of at least one of a posture or a respiration cycle; obtain cardiac activity (CA) signals for a series of beats; identify whether a characteristic of interest (COI) from at least a first segment of the CA signals exceeds a COI limit; analyze the motion data to determine whether at least one of the posture or respiration cycle at least in part caused the COI to exceed the COI limit. Based on the analyzing operation, the methods and systems automatically adjust a CA sensing parameter utilized by the medical device to detect R-waves in subsequent CA signals; and detect an arrhythmia based on a presence or absence of one or more of the R-waves in at least a second segment of the CA signals.
    Type: Grant
    Filed: October 1, 2019
    Date of Patent: January 24, 2023
    Assignee: Pacesetter, Inc.
    Inventors: Donald Hopper, Luke C. McSpadden, Fujian Qu, Gene Bornzin, Sinny Delacroix
  • Patent number: 11547862
    Abstract: A charging energy control system includes an implantable medical device (IMD) and an external charger for effectuating wireless power transfer. The IMD receives charging energy to recharge a battery during an ON period and rejects the charging energy during an OFF period. A series switch is disposed between the IMD's coil and rectifier circuitry that is controlled by voltage regulation circuitry operative to generate a clamp control signal configured to detune the coil in the OFF state.
    Type: Grant
    Filed: November 6, 2019
    Date of Patent: January 10, 2023
    Assignee: ADVANCED NEUROMODULATION SYSTEMS, INC.
    Inventor: William Winstrom
  • Patent number: 11547341
    Abstract: A system and method for non-invasively monitoring the hemodynamic state of a patient by determining on a beat-by-beat basis the ratio of lusitropic function to inotropic function as an index of myocardial well-being or pathology for use by clinicians in the hospital or by the patient at home. In one embodiment of the system a smartphone running an application program that is connected through the internet to the cloud processes electronic signals, first, from an electrocardiogram device monitoring electrical cardiac activity, and second, from a seismocardiogram device monitoring mechanical cardiac activity in order to determine such ratio as an instantaneous measurement of the hemodynamic state of the patient, including such states as sepsis, myocardial ischemia, and heart failure.
    Type: Grant
    Filed: January 11, 2021
    Date of Patent: January 10, 2023
    Assignee: Cooper Health System
    Inventor: Robert Alan Hirsh
  • Patent number: 11541239
    Abstract: Methods are disclosed for treating a subject having a disease or disorder comprising stimulating a nerve of the subject with a corrective stimulus pattern derived from a disease-specific, condition-specific, endogenous mediator-specific or pharmacologic agent-specific neurogram in an amount and manner effective to treat the disease or disorder.
    Type: Grant
    Filed: November 26, 2019
    Date of Patent: January 3, 2023
    Assignee: The Feinstein Institutes for Medical Research
    Inventors: Kevin J. Tracey, Sangeeta S. Chavan
  • Patent number: 11541244
    Abstract: A medical implant includes a first component having a surface and a plurality of electrical contacts and a second component having a surface and a plurality of electrical contacts. Each contact of the first component contacts an assigned contact of the second component in an electrically conducting manner. A seal is disposed between the two surfaces for sealing the contacts. The seal and the two surfaces are formed of a thermoplastic material. The seal is fused to the two surfaces for sealing the contacts and the seal is meltable so as to separate the two components from one another. A method for producing a medical implant is also provided.
    Type: Grant
    Filed: September 11, 2020
    Date of Patent: January 3, 2023
    Assignee: DYCONEX AG
    Inventors: Eckardt Bihler, Marc Hauer
  • Patent number: 11534608
    Abstract: Transdermal electrical stimulation (TES) applicators that are wearable and configured to attached to a subject's pinna (ear) and adapted to apply TES to modulate the subject's cognitive and/or physiological state. These apparatuses may be configured so that they can be worn against the ear (e.g., the cymba of the ear) to deliver TES. Also described herein are methods of using them to modulate a subject's cognitive state. These TES applicators may also be adapted to function as audio headphones for concurrent delivery of TES and audible signals (e.g., music).
    Type: Grant
    Filed: September 30, 2019
    Date of Patent: December 27, 2022
    Assignee: IST, LLC
    Inventors: William J. Tyler, Wing Law, Douglas Jeffery, Rafal Piersiak
  • Patent number: 11529084
    Abstract: The detection and diagnosis of a variety of cardiovascular disorders and levels of heart condition, using a novel method and system, according to a comprehensive analysis of cardiac electrical signal via the frequency domain, time domain, spatial domain.
    Type: Grant
    Filed: September 8, 2015
    Date of Patent: December 20, 2022
    Inventor: Dan Qun Fang
  • Patent number: 11529528
    Abstract: Systems and methods for wireless stimulation of biological tissue (e.g. nerves, muscle tissue, etc.) and, in one exemplary implementation, to therapy for glaucoma based on the wireless administration of energy to the eye of a mammalian subject (e.g. human, rodent, etc.) to reduce an elevated intraocular pressure (IOP) involving the use of a multi-coil wireless power transfer assembly. The multi-coil wireless power transfer assembly may be used alone or in combination with a stimulation coil that can be implanted in the eye of a mammalian subject or within a contact lens worn by a mammalian subject.
    Type: Grant
    Filed: August 6, 2018
    Date of Patent: December 20, 2022
    Assignee: Purdue Research Foundation
    Inventors: Pedro P. Irazoqui, Gabriel Simon, Gabriel Omar Albors, Jack Williams, Quan Yuan, Zhi Wang, Curtis Slaubaugh
  • Patent number: 11529083
    Abstract: A physiological status evaluation method and a physiological status evaluation apparatus are provided. The method includes the following: obtaining original electrocardiogram data of a user by an electrocardiogram detection apparatus; converting the original electrocardiogram data into digital integration data; obtaining a plurality of physiological characteristic parameters according to the digital integration data; filtering the physiological characteristic parameters for at least one notable characteristic parameter through at least one filter model, where decision importance of the at least one notable characteristic parameter in a decision process of the at least one filter model is greater than a threshold; building a prediction model according to the at least one notable characteristic parameter; and evaluating a physiological status of the user through the prediction model.
    Type: Grant
    Filed: October 29, 2020
    Date of Patent: December 20, 2022
    Assignees: Acer Incorporated, Taipei Veterans General Hospital, Acer Medical Inc.
    Inventors: Chun-Hsien Li, Tsung-Hsien Tsai, Jun-Hong Chen, Wei-Ting Wang, Yin-Hao Lee, Hao-Min Cheng
  • Patent number: 11517204
    Abstract: Described herein is a computer implemented method of measuring the determining the Left Ventricular Ejection Fraction (LVEF) of a patient. The S Wave, P Wave, R Wave and T Wave are continually measured using an ECG apparatus. The LVEF is computed as a function of S Wave, P Wave, R Wave and T Wave. The system described herein includes an ECG apparatus and an analytical computing device for computing the LVEF.
    Type: Grant
    Filed: December 14, 2020
    Date of Patent: December 6, 2022
    Inventor: Abhijit Ray
  • Patent number: 11517318
    Abstract: Some embodiments of a system or method for treating heart tissue can include a control system and catheter device operated in a manner to intermittently occlude a heart vessel for controlled periods of time that provide redistribution of blood flow. In particular embodiments, the system and methods may be configured to monitor at least one input signal detected at a coronary sinus and thereby execute a process for determining a satisfactory time period for the occlusion of the coronary sinus. In further embodiments, after the occlusion of the coronary sinus is released, the control system can be configured to select the duration of the release phase before the starting the next occlusion cycle.
    Type: Grant
    Filed: February 8, 2021
    Date of Patent: December 6, 2022
    Assignee: Miracor Medical SA
    Inventors: Werner Mohl, Gregor Neumayr, Alem Jusic
  • Patent number: 11510603
    Abstract: Devices and methods for stimulation and recording of muscle responses for determining degree of neuromuscular blockade, particularly relevant to elicitation of such responses in those under the influence of anesthesia. A system for estimating the degree of neuromuscular blockade includes at least one stimulating electrode, at least one recording electrode, a pulse generator for providing stimulation to a nerve through the stimulating electrode, and a computing device configured to: apply stimuli to the nerve according to a stimulation protocol, wherein the stimulation protocol provides a plurality of stimulation sequences that vary in frequency of pulses in the stimulation sequence, frequency of the stimulation sequences, number of pulses in the stimulation sequence, or all of the above; measure, by the recording electrode, electrical responses of a muscle; and estimate the degree of neuromuscular blockade based on changes in the electrical responses of the muscle during a stimulation sequence.
    Type: Grant
    Filed: December 18, 2020
    Date of Patent: November 29, 2022
    Assignee: SafeOp Surgical, Inc.
    Inventors: Robert Snow, Richard O'Brien
  • Patent number: 11511106
    Abstract: The present invention is directed to transcutaneous electrical nerve stimulation (TENS) devices which utilize novel stimulation waveforms and novel arrangements of TENS electrodes to improve the efficiency of power consumption while enhancing therapeutic effects.
    Type: Grant
    Filed: December 15, 2020
    Date of Patent: November 29, 2022
    Assignee: Neurometrix, Inc.
    Inventors: Glenn Herb, Andres Aguirre, Xuan Kong, Shai N. Gozani
  • Patent number: 11504045
    Abstract: Provided are an apparatus and method for detecting ventricular depolarization (QRS) of an electrocardiogram (ECG). The apparatus includes an input unit configured to receive an ECG signal, a memory configured to store a program for detecting R and ventricular depolarization using the ECG signal, and a processor configured to execute the program, wherein the processor detects a QRS interval and an R-peak using a first-order derivative filter and a max-filter.
    Type: Grant
    Filed: November 24, 2020
    Date of Patent: November 22, 2022
    Assignee: Electronics and Telecommunications Research Institute
    Inventors: Tae Wuk Bae, Kee Koo Kwon, Kyu Hyung Kim
  • Patent number: 11504532
    Abstract: A chest tube device with neurostimulation is provided, along with a method of electrically stimulating at least one of (i) one or more peripheral nerves and (ii) one or more nerve fibers of a thoracic region of a patient, to mitigate pain in patients undergoing chest tube implantation. The chest tube device includes a tubular member and an electro-analgesic region to provide neurostimulation to one or more peripheral nerves and/or nerve fibers of the thoracic region of the patient. The method includes electrically stimulating one or more peripheral nerves and/or nerve fibers of the thoracic region of the patient, and hyperpolarizing the one or more peripheral nerves and/or nerve fibers of the thoracic region to (i) reduce an amount of pain signals from being transmitted to the brain of the patient and/or (ii) prevent pain signals from being transmitted to the brain of the patient.
    Type: Grant
    Filed: February 16, 2018
    Date of Patent: November 22, 2022
    Assignee: COH HOLDCO INC.
    Inventor: Peter Ungjo Baik