Abstract: An ophthalmic surgical cassette for removably receiving in a cassette receiving mechanism of an ophthalmic surgical system. The system includes first and second plunger valves. The cassette includes a body having a rear surface, an irrigation inlet for receiving irrigation fluid from a source, a first irrigation outlet for providing irrigation fluid to a first ophthalmic microsurgical instrument for use in an anterior segment ophthalmic surgical procedure, a first manifold fluidly coupling the irrigation inlet with the first irrigation outlet, a second irrigation outlet for providing irrigation fluid to a second ophthalmic microsurgical instrument for use in a posterior segment ophthalmic surgical procedure, and a second manifold fluidly coupling the irrigation inlet with the second irrigation outlet.

Abstract: This invention prevents the danger of falling of body temperature by making the blood temperature similar to the body temperature in the injection of Ringer's solution fluid or blood transfusion, and also alleviates the patient's pain and improves the speed at which Ringer's solution fluid or blood enters the body. The warming device is much cheaper than previously released products, and small and light in weight, and allows blood or solution fluids to flow most effectively by allowing sufficient time for heat transfer as a pack type. The operation is convenient and sanitary in its single usage only. The inventive purpose has the methods of utilizing the temperature sensor in adjusting temperature by utilizing them PTC heating element's resistance specialty against the temperature as well as temperature sensor.

Abstract: A catheter includes a pull wire which extends through two different lumen and attaches to the distal end of the catheter at an off-axis location. By tensioning the pull wire, the catheter can assume various complex curves, depending on the respective lumen through which the pull wire passes.

Abstract: A medical device includes a cavity communicable with a body to deliver or to receive a fluid, and a radiation source configured to expose a portion of the cavity to radiation.

Abstract: Medical diagnostic ultrasound catheters are provided with improved materials for dielectric withstand strength. In one aspect, the catheter includes a braid of non-conductive material. The non-conductive braid reduces the capacitive: coupling effects and allows smaller catheters or a greater number of conductors. The non-conductive braid provides both compressive and tensile strength to transmit the torque applied to the catheter. The non-conductive braid also allows fusing of components while decreasing the risk of defective manufacture. In another aspect, a dielectric film, such as a polyester film, is positioned between the transducer and any lens or window. The dielectric film allows thinner window lenses to be used, allowing smaller catheters or larger transducers. The dielectric film may also increase the sensitivity of the transducer to acoustic energy.

Abstract: A fluid dispenser for use in controllably dispensing fluid medicaments, such as antibiotics, oncolytics, hormones, steroids, blood clotting agents, analgesics, bio pharmaceuticals and like medicinal agents from a reservoir that has been filled from prefilled containers. The fluid dispenser includes a housing to which fill vials can be connected for filling the dispenser reservoir with the fluid, and a stored energy source provided in the form of a substantially constant-force spring that provides the force necessary to continuously and uniformly expel fluid from the device reservoir. The fluid dispenser also includes a fluid flow control assembly that precisely controls the flow of the medicament solution to the patient.

Abstract: A dual balloon catheter apparatus for controlling postpartum hemorrhage in uterine or vaginal cavities or hemorrhage in other body cavities, comprising: (1) a catheter having an inflation lumen and a deflation lumen; (2) a first inflatable balloon in fluid communication with the inflation lumen; and (3) a second inflatable balloon encompassing the first balloon and in fluid communication with the deflation lumen. A gaseous inflation medium can be introduced from an external gas source through the inflation lumen to inflate the first balloon, so as to apply a substantially even pressure along a substantial portion of an inner surface of a uterine cavity to reduce or eliminate bleeding along such inner surface. The second inflatable balloon functions to confine any gaseous inflation medium that escapes from the first balloon, due to leakage or rapture of such first balloon, and to discharge such escaped gaseous inflation medium through the deflation lumen.

Abstract: An aspiration flow resistor 10 includes an inlet 12 and an outlet 14. A housing 16 is connected to the inlet 12 and outlet 14. A series of spaced walls 18 are disposed between the inlet 12 and the outlet 14. The walls 18 and the inlet 12 and the outlet 14 together with the housing 16 define a plurality of aspiration flow chambers 22. As aspirant flows from the inlet 12 to the outlet 14, a pressure decrease in the aspirant flow occurs at each wall 18 to provide resistance to aspirant flow.

Abstract: A catheter adapted to deliver therapeutic or diagnostic agents to a target tissue of a human body is disclosed. A catheter in accordance with the present invention comprises a magnetic field source for directing the flow of the therapeutic of diagnostic agent. The therapeutic or diagnostic agent may be conjugated with diamagnetic particles, ferromagnetic particles, super paramagnetic particles, or paramagnetic particles.

Abstract: A device for application of material to a surface, for example, biocompatible material to a tissue surface in a medical or clinical setting, is adapted to receive one or more biocompatible materials and one or more sources of pressurized medical gas, and to deliver these biocompatible materials via the medical gas(es) to a tissue surface or other surface. A regulation system controls flow of medical gas at a variety of pressures, and flow of biocompatible agent or agents, allowing agents to be sprayed or otherwise deployed onto a tissue surface. Switching apparatus operably connected to the regulation system directs a set of preset treatment positions allowing sequential application of biocompatible materials under various conditions in conjunction with an overall treatment protocol. The device can be used to apply a photoinitiating primer and polymeric sealant to a tissue surface, followed by light activation to form a polymer coating on the surface.

Abstract: A microcatheter system that allows for vascular infusion into retinal veins for extended periods of time. The microcatheter system includes a flexible cannula that is inserted into the retinal vein lumen and that remains stably within the retinal vein lumen without being held by a robot, micromanipulator or similar holding devices. The microcatheter system is particularly suitable for the treatment of retinal venous occlusive disease.

Abstract: A device for delivering a medicated product into a bodily cavity includes a barrel member having a dispensing end, a proximal end, which is positioned opposite the dispensing end, and a bore, which extends through the barrel member. The bore is sized and shaped so as to receive a medicated product therein and includes an opening formed in the dispensing end of the barrel member. The opening is sized and shaped so as to permit a medicated product received in the bore to be dispensed therethrough. The applicator is also provided with a plunger member movably extending through the bore of the barrel member for dispending a medicated product from the bore through the opening. The barrel member includes at least one substantially flexible section located between the dispending end and the proximal end such that the barrel member is bendable about the flexible section.

Abstract: A catheter designed to be anchored in an internal cavity of a patient such as a drainage catheter employs a novel hub design. The hub has a slide member slidably coupled to the hub and a latch that latches the hub and the slide member together when the slide member slidably moves relative to the hub. Preferably, latching takes place when the slide member moves relative to the hub in an axial direction of the hub. A manually operable release member is provided on the hub such that the latch is disabled from unlatching unless the release member is manually operated. This feature advantageously limits a person's ability to accidentally unlatch the hub.

Abstract: A sealing rubber closure is provided for use with a syringe/container specified by ISO (the International Organization of Standardization) and having a Luer nozzle to be inserted into a Luer-nozzle-receiving part of the sealing rubber closure. The Luer-nozzle-receiving part is configured, on a side of an inner end portion thereof, in an untapered cylindrical form to assure tight-fitted insertion of a free end portion of the Luer nozzle and, on a side of a Luer-nozzle-receiving opening thereof, in a tapered, substantially cylindrical form to assure tight-fitted insertion of a basal end portion of the Luer nozzle. A plastic film is laminated on the sealing rubber closure at least in an area of the Luer-nozzle-receiving part, where a free end of the Luer nozzle is to be maintained in contact with the sealing rubber closure.

Abstract: A solid drug perforator (SSP) system and an associated drug reservoir are provided for delivering theraputic, prophylactic and/or cosmetic compounds, for nutrient delivery and for drug targeting. For drug delivery, the SSP system includes an active drug ingredient and a matrix of perforator material that biodegrades or dissolves quickly upon contact with a patient's body. The SSP system provides a skin barrier perforator and a controller for prompt initiation and cut-off of drug delivery. In a preferred method of transdermal drug delivery, an SSP system containing a selected drug penetrates into an epidermis or dermis, and the drug is promptly released from the (dissolving) SSP system perforator. An additional drug is optionally delivered from a patch reservoir through skin pores created by insertion of the perforator. Formulation and fabrication procedures for the SSP and associated reservoir are also provided. An SSP system can be fabricated with variety of shapes and dimensions.

Abstract: A cap (16) is provided for the type of injection device (1) which presents a needle assembly (11) to the exterior thereof for removal after use. The cap is of two part construction with a shell (17) of hard material, having opposite inwardly flexible tongues (19) defined by slots in the shell, and an over-mould (18) of relatively soft deformable material, extending over at least the tongues and the slots. The tongues are squeezable towards each other through the over-mould to grip the needle assembly when the cap is fitted after an injection, thus enabling the needle assembly to be removed with the cap so that the user does not come into contact with the used needle.

Abstract: Microcannulae are constructed with multiple components in a composite design, allowing the microcannulae to have varying mechanical and delivery properties that will enable ophthalmic treatments by minimally invasive means. The microcannula includes at least one flexible, tubular communicating element with an outer diameter of 350 microns or less, a proximal connector for introduction of materials, energy or tools. It may also include a reinforcing member attached to the communicating element, which may be designed to create variable stiffness along the length of the microcannula. The microcannula may also include other features such as a signal beacon near the distal tip.

Abstract: An improved surgical console for use with a handheld tissue fragmentation device includes portable base having an upper portion. An adjustable display head is mounted to the upper portion of the base. The display head provides rotational and translational adjustment relative to the base. An aspiration system is coupled to the fragmentation device for aspirating fluid and tissue fragmented by the fragmentation device from a surgical site. An irrigation system is also coupled to the fragmentation device for supplying irrigating fluid to the surgical site for suspending tissue fragmented by the fragmentation device. A power system is coupled to the fragmentation device for energizing a transducer of the fragmentation device for fragmenting tissue.

Abstract: A method and device for administering material to an eye during an eye-open interval. The device includes, an electronically controllable fluid delivery element and a detector in communication with the electronically controllable fluid delivery element. The detector is capable of discerning at least a portion of an eye-blink event and producing a signal actionable on the electronically controllable fluid delivery element.

Abstract: A device and methods are described for a non-invasive transnasal and transocular drug delivery to the central nervous system using iontophoresis technology. By delivered through the olfactory nerve and the optical nerve, a biologically active substance of interest can be enhanced to be delivered into the CNS and CSF and bypassing the blood-brain barrier. Such drug delivery system can also be enhanced by using phonophoresis and other enhancement techniques.