Patents Examined by Catherine S. Williams
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Patent number: 7468027Abstract: Methods are provided for partial aortic obstruction for cerebral perfusion augmentation in patients suffering from global or focal cerebral ischemia. Alternatively, the methods can be used to partially obstruct aortic blood flow to condition the spinal cord to secrete neuroprotective agents prior to abdominal aortic aneurysm repair. Partial obstruction of a vessel can be accomplished by a device comprising an elongate catheter and a distally mounted expandable member. The expandable member may comprise one or two balloons. Other medical devices, such as an angioplasty, stent, or atherectomy catheter, can be inserted distal the expandable member to provide therapeutic intervention.Type: GrantFiled: October 21, 2005Date of Patent: December 23, 2008Assignee: CoAxia, Inc.Inventors: Denise R. Barbut, Peter T. Keith, Steven W. Berhow, Jon P. St. Germain
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Patent number: 7455654Abstract: An apparatus for transdermally delivering a nicotine-based agent to a tobacco or nicotine user comprising a microprojection member having a plurality of microprojections that are adapted to pierce the stratum corneum of the tobacco user, the microprojection member having a biocompatible coating disposed thereon that includes a nicotine-based agent.Type: GrantFiled: October 21, 2004Date of Patent: November 25, 2008Assignee: Alza CorporationInventors: Michel J. N. Cormier, Robert M. Gale, Andrew G. Scott
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Patent number: 7438703Abstract: A safety shield apparatus is disclosed which includes a needle having a distal portion defining a longitudinal axis which is angularly displaced relative to a longitudinal axis defined by a proximal portion of the needle. A shield is mounted with the needle and extensible, via a tubular needle guide movable along the needle, between a retracted position and an extended position. The apparatus may include a needle hub configured to support the proximal portion of the needle. The needle hub can include an appendage which may have at least one opening to facilitate manipulation thereof. A distal end of the shield can be attached to a planar contact surface. The shield may also include a latch engageable with the needle.Type: GrantFiled: December 6, 2001Date of Patent: October 21, 2008Assignee: Tyco Healthcare Group LPInventors: Roy L. Barrus, David L. Thorne, Charles V. Owen, Donald D. Solomon, F. Mark Ferguson, Michael Thorne, Stephen Brown, Gale H. Thorne, Jr.
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Patent number: 7393339Abstract: A multi-lumen catheter defined by at least two separate tip sections distal to a dividing point includes strategic placement of openings in the tip sections to facilitate fluid flow and minimize typical problems associated with catheters. In a multi-lumen catheter having tip sections with a releasably joined or splittable region, the bond strength between the tip sections is varied along their length such that an increasing separation force is required to separate the tip sections from one another distal to the dividing point. Delivery of a multi-lumen catheter is improved with respect to both sheathed and non-sheathed delivery methods, in which a friction reducing structure is provided on either the catheter, delivery sheath or both to provide a buffer for a sheathed delivery and in which a unique guidewire aperture or additional lumen is provided in at least one of the tip sections for a non-sheathed delivery.Type: GrantFiled: February 21, 2003Date of Patent: July 1, 2008Assignee: C. R. Bard, Inc.Inventors: John A. Zawacki, Kelly B. Powers, John G. Evans, Guy Rome
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Patent number: 7364568Abstract: A transdermal transport device includes a reservoir for holding a formulation of an active principle, and a needle with a bore extending along the length of the needle from a first end of the needle to a second end of the needle. The second end is substantially aligned to a plane parallel to a body surface of a biological body when the device is placed on the body surface. The device also includes an actuator which pumps the formulation through the bore of the needle between a target area of the body and the reservoir.Type: GrantFiled: October 21, 2002Date of Patent: April 29, 2008Assignee: Massachusetts Institute of TechnologyInventors: Aimee B. Angel, Ian W. Hunter
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Patent number: 7331942Abstract: An I.V. flush syringe assembly includes a barrel having an inside surface defining a chamber for retaining fluid, an open proximal end and a distal end including a distal wall with an elongate tip extending distally therefrom having a passageway therethrough in fluid communication with the chamber. A plunger having an elongate body portion and a stopper slidably positioned in fluid-tight engagement with the inside surface of the barrel is provided. Anti-reflux structure for controlling stopper deflection when fluid has been delivered from the chamber and the stopper is in contact with the distal wall is provided.Type: GrantFiled: September 23, 2003Date of Patent: February 19, 2008Assignee: Becton, Dickinson and CompanyInventors: Thomas A. Alheidt, James John Timko
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Patent number: 7331940Abstract: A percutaneous access device is provided including a sleeve having an inner lumen extending therethrough that is adapted to slidably receive a catheter, and at least one flange disposed around the sleeve and adapted to be positioned adjacent a tissue surface. In a preferred embodiment, the device includes a first flange disposed around the sleeve and adapted to be positioned adjacent a first tissue surface, and a second flange disposed around the sleeve and spaced apart from the first flange such that the second flange is adapted to be disposed adjacent a second tissue surface opposed to the first tissue surface. In use, the flanges 16, 18 are positioned on opposed sides of tissue so that the device 10 is effective to prevent tissue surrounding the percutaneous access device from coming into contact with the catheter as it is introduced through the sleeve 12.Type: GrantFiled: May 27, 2005Date of Patent: February 19, 2008Assignee: Codman & Shurtleff, Inc.Inventor: Bob Sommerich
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Patent number: 7329233Abstract: An insufflation apparatus includes an elongated sleeve defining a longitudinal axis and having a proximal end and a distal end with a sharpened tip, an insufflation housing connected to the proximal end of the elongated sleeve and defining a port for receipt of insufflation gases, and a stylet disposed within the elongated sleeve and defining a passageway to direct the insufflation gases from the port into a body cavity. The stylet is movable between an extended position wherein the distal end of the stylet extends beyond the sharpened tip of the elongated sleeve and a retracted position wherein the distal end of the stylet is proximal of the sharpened tip of the elongated sleeve. A biasing member may be engagable with the stylet so as to bias the stylet toward the extended position. Preferably, the housing has a translucent wall and the stylet is dimensioned so that the proximal end of the stylet is visible through the translucent wall when the stylet is in the retracted position.Type: GrantFiled: October 5, 2004Date of Patent: February 12, 2008Assignee: Tyco Healthcare Group LPInventor: Richard D. Gresham
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Patent number: 7322965Abstract: A method for preventing medical device-associated microorganism infection includes the steps of providing a medical device and incorporating an effective amount of an oxazolidinone compound, such as linezolid, into the medical device.Type: GrantFiled: January 21, 2003Date of Patent: January 29, 2008Assignee: Pharmacia & Upjohn CompanyInventors: John Kenneth Gibson, Charles W. Ford, Paul J. Pagano
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Patent number: 7322955Abstract: The present invention relates to a medicament injection apparatus. It is desirable following injection of a medicament to wait a short time before withdrawing the needle unit from the patient to allow injected medicament to disperse within the patient to reduce the risk of some of the injected medicament escaping through the needle wound and so not being dispersed into the patient as desired. This problem is particularly acute where a patient uses the apparatus to self-administer a dose since, where this waiting period is indicated to a user, the waiting period is a set time independent of whether the size of the dose to be injected. The user often feels that for a small dose it is not as important to leave the needle unit within the body for the full waiting period and so does not allow the waiting period properly to elapse.Type: GrantFiled: January 8, 2003Date of Patent: January 29, 2008Assignee: DCA Design International LimitedInventors: Mayer Azizi, Robert Woolston
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Patent number: 7320675Abstract: A drug delivery system detects a cardiac condition indicative of a need for increasing a cardiac metabolic level and, in response, releases a drug into tissue or blood to shift a source of metabolically synthesized energy fueling cardiac contraction from fatty acid to glucose. One example of such a system includes an implantable device detecting an ischemia and a transdermal drug delivery device delivering a drug when an ischemic condition is detected. Another example of such a system includes one or more implantable devices detecting a predefined change in cardiac metabolic level and delivering a drug when the change is detected. Such systems are applied to treat, for example, patients suffering ischemia and/or heart failure and patients having suffered myocardial infarction.Type: GrantFiled: August 21, 2003Date of Patent: January 22, 2008Assignee: Cardiac Pacemakers, Inc.Inventors: Joseph M. Pastore, Julio C. Spinelli, Helen L. Reeve, Jeffrey Ross, Rodney W. Salo, Allan Shuros
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Patent number: 7316676Abstract: An apparatus and minimally invasive method for removing fluid from a subretinal space to allow a detached retina to flatten. An apparatus, comprising a fluid withdrawal device and a guide for advancing and placing the device, is positioned on the exterior eye surface at the detachment site. Various embodiments of the apparatus are disclosed. Using the guide, the surgeon advances the device into the fluid-filled space and drains fluid, allowing the retina to flatten. Additional injection of saline or gas into the vitreous cavity normalizes intraocular pressure, and the patient is ambulatory immediately afterward. Unlike other retinal attachment techniques, in the inventive procedure the patient receives only a local anesthetic, and has no restraint on head movement.Type: GrantFiled: August 20, 2002Date of Patent: January 8, 2008Inventors: Gholam A. Peyman, Charalampos Livir-Rallatos
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Patent number: 7306576Abstract: In a medical needle device having a shield for reduction of needlestick injuries, a protrusion is formed on an outer peripheral surface of a hub to which a needle is mounted, a height of the protrusion being set so that the protrusion protrudes beyond an inner diameter of a shield tube, and a gate groove is formed at an inner surface of the shield tube to extend from a front end to the vicinity of a rear end, dimensions of the gate groove being such that the protrusion can fit in a front end portion of the gate groove. In a state where the protrusion is exposed from the front end of the shield tube, the hub can rotate with respect to the shield tube. At a rotational position of the protrusion at which it does not face a front end of the gate groove, a position of the hub is limited so as not to move toward a rear end side of the shield tube due to engagement of the protrusion with a front end face of the shield tube.Type: GrantFiled: July 4, 2003Date of Patent: December 11, 2007Assignee: JMS Co., Ltd.Inventors: Susumu Hongo, Takafumi Kiyono, Kuniharu Moriwaki
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Patent number: 7306617Abstract: A catheter with proximal and distal ends having a spiral centering device attached near the catheter distal end. The spiral centering device has at least one spiral strut having a proximal end and a distal end. The spiral centering device resiliently tends to center the distal end portion of the catheter, steering the catheter away from the vessel wall during insertion through the vasculature and toward the treatment site. The spiral centering catheter may facilitate access to tortuous anatomy by preventing the distal catheter tip from catching on irregularities in the lumenal surface. If a stent is provided on the catheter, the spiral centering catheter may also facilitate uniform stent expansion by stabilizing the catheter during stent deployment.Type: GrantFiled: October 26, 2004Date of Patent: December 11, 2007Assignee: Cordis CorporationInventor: David C. Majercak
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Patent number: 7303545Abstract: A butterfly-needle set has an elongated two-part case forming a pair of transversely open slots. An elongated needle in the case has a pair of generally coplanar and oppositely projecting wings projecting out of the case through the slots. The slots are sufficiently long that the needle can move longitudinally between a front position with the needle projecting from a front end of the case and a rear position with the needle completely within the case. An elastically deflectable spring element projects at a small acute angle toward a rear end of the case into at least one of the slots so as to deflect elastically and allow the needle to move from the front position into the rear position and to block movement of the needle from the rear position into the front position.Type: GrantFiled: November 20, 2002Date of Patent: December 4, 2007Assignee: Sarstedt AG & Co.Inventor: Walter Sarstedt
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Patent number: 7300428Abstract: Devices, compositions, and methods for achieving non-surgical lung volume reduction (e.g., bronchoscopic lung volume reduction (BLVR)) are described. BLVR can be carried out by collapsing a region of the lung, adhering one portion of the collapsed region to another, and promoting fibrosis in or around the adherent tissue.Type: GrantFiled: December 11, 2004Date of Patent: November 27, 2007Assignee: Aeris Therapeutics, Inc.Inventor: Edward P. Ingenito
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Patent number: 7302293Abstract: The invention provides an improved electrotransport drug delivery system for analgesic drugs, namely fentanyl and sufentanil. The fentanyl/sufentanil is provided as a water soluble salt (e.g., fentanyl hydrochloride), preferably in a hydrogel formulation, for use in an electrotransport device (10). In accordance with the present invention, a transdermal electrotransport delivered dose of fentanyl/sufentanil is provided which is sufficient to induce analgesia in (e.g., adult) human patients suffering from moderate-to-severe pain associated with major surgical procedures.Type: GrantFiled: October 28, 2005Date of Patent: November 27, 2007Assignee: ALZA CorporationInventors: Mary Southam, Keith J. Bernstein, Henk Noorduin
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Patent number: RE45417Abstract: A stowable chair system having a base assembly and a back pivotably connected to the base assembly. A first leg retention assembly operatively coupled to the base assembly to selectively retain and position legs in a seating configuration. A second leg retention assembly separate from the first leg retention assembly to selectively retain and position the legs in a stowing configuration.Type: GrantFiled: May 2, 2014Date of Patent: March 17, 2015Assignee: SmithWorks, Inc.Inventor: David L. Smith
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Patent number: RE45790Abstract: A device for the transvascular implantation and fixation of prosthetic heart valves having a self-expanding heart valve stent (10) with a prosthetic heart valve (11) at its proximal end is introducible into a patient's main artery. With the objective of optimizing such a device to the extent that the prosthetic heart valve (11) can be implanted into a patient in a minimally-invasive procedure, to ensure optimal positioning accuracy of the prosthesis (11) in the patient's ventricle, the device includes a self-expanding positioning stent (20) introducible into an aortic valve positioned within a patient. The positioning stent is configured separately from the heart valve stent (10) so that the two stents respectively interact in their expanded states such that the heart valve stent (10) is held by the positioning stent (20) in a position in the patient's aorta relative the heart valve predefinable by the positioning stent (20).Type: GrantFiled: August 7, 2014Date of Patent: November 3, 2015Assignee: JENAVALVE TECHNOLOGY GMBHInventors: Hans-Reiner Figulla, Markus Ferrari, Christoph Damm
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Patent number: RE45962Abstract: A device for the transvascular implantation and fixation of prosthetic heart valves having a self-expanding heart valve stent (10) with a prosthetic heart valve (11) at its proximal end is introducible into a patient's main artery. With the objective of optimizing such a device to the extent that the prosthetic heart valve (11) can be implanted into a patient in a minimally-invasive procedure, to ensure optimal positioning accuracy of the prosthesis (11) in the patient's ventricle, the device includes a self-expanding positioning stent (20) introducible into an aortic valve positioned within a patient. The positioning stent is configured separately from the heart valve stent (10) so that the two stents respectively interact in their expanded states such that the heart valve stent (10) is held by the positioning stent (20) in a position in the patient's aorta relative the heart valve predefinable by the positioning stent (20).Type: GrantFiled: August 7, 2014Date of Patent: April 5, 2016Assignee: JenaValve Technology GmbHInventors: Hans-Reiner Figulla, Markus Ferrari, Christoph Damm