Patents Examined by Celeste A Roney
  • Bioactive borate glass and methods thereof
    Patent number: 11198638
    Abstract: A bioactive borate glass composition including, for example: 30 to 60% B2O3; 0.5 to 20% ZrO2; 3 to 30% Na2O; 0.1 to 15% K2O; 0.1 to 15% MgO; 5 to 30% CaO; and 1 to 5% P2O5 in mole percents based on 100 mol % of the total composition. Also disclosed is a method of making and method of using the compositions and the bioactive borate glass dentin treatment formulations.
    Type: Grant
    Filed: November 28, 2018
    Date of Patent: December 14, 2021
    Assignee: Corning Incorporated
    Inventors: Huayun Deng, Qiang Fu, Ying Wei
  • Liposomal nanoparticle essential oil composition for nostril administration
    Patent number: 11166909
    Abstract: The invention pertains to liposomes containing an oil-in-water emulsion of a selected combination of at least ten different essential plant oils produced with phospholipids found in human membranes and methods for treating respiratory diseases, disorders or conditions by administering the liposomes into the nose and respiratory system.
    Type: Grant
    Filed: April 20, 2021
    Date of Patent: November 9, 2021
    Assignee: King Abdulaziz University
    Inventors: Taha Kumosani, Elie Barbour, Werner Krull, Soonham Yaghmoor
  • Peroxymonosulfate toothpowder composition for tenacious stains
    Patent number: 11166890
    Abstract: A solid oral care composition, e.g., a tablet or powder, comprising an alkali metal peroxymonosulfate as an effective bleaching agent for the bleaching of tenacious tooth stains, such as tobacco stains and coffee stains.
    Type: Grant
    Filed: August 11, 2016
    Date of Patent: November 9, 2021
    Assignee: Colgate-Palmolive Company
    Inventors: Cajetan Dogo-Isonagie, Lin Fei, Suman Chopra, Jennifer Gronlund
  • Bioactive borate glass and methods thereof
    Patent number: 11161774
    Abstract: A bioactive borate glass composition including, for example: 30 to 60% B2O3; 0.5 to 20% ZrO2; 3 to 30% Na2O; 0.1 to 15% K2O; 0.1 to 15% MgO; 5 to 30% CaO; and 1 to 5% P2O5 in mole percents based on 100 mol % of the total composition. Also disclosed is a method of making and method of using the compositions and the bioactive borate glass dentin treatment formulations.
    Type: Grant
    Filed: November 28, 2018
    Date of Patent: November 2, 2021
    Assignee: Corning Incorporated
    Inventors: Huayun Deng, Qiang Fu, Ying Wei
  • Method for preparing liposomes containing an essential oil in an oil-in-water emulsion
    Patent number: 11160752
    Abstract: The invention pertains to liposomes containing an oil-in-water emulsion of a selected combination of at least ten different essential plant oils produced with phospholipids found in human membranes and methods for treating respiratory diseases, disorders or conditions by administering the liposomes into the nose and respiratory system.
    Type: Grant
    Filed: March 24, 2021
    Date of Patent: November 2, 2021
    Assignee: King Abdulaziz University
    Inventors: Taha Kumosani, Elie Barbour, Werner Krull, Soonham Yaghmoor
  • Connective tissues, such as bone, dentin or pulp, regenerative material comprising calcium silicate
    Patent number: 11160905
    Abstract: A regenerative material in the connective tissues (such as bone, dentin or pulp) regeneration field. More precisely, a connective tissue regenerative material, preferably a bone, dentin or pulp regenerative material, including: a porous polymer matrix having interconnected pores; and non-hydrated calcium silicate particles; wherein: the polymer matrix is anhydrous; the non-hydrated calcium silicate particles have a d50granulometry, preferably ranging from 0.05 ?m to less than the average diameter size of the pores of the matrix; and the non-hydrated calcium silicate particles being coated on the inside walls of the pores of the matrix. Also, a method for preparing the connective tissue regenerative material and uses of the regenerative materials, such as in the dental field; especially, for providing regenerative materials with improved biomechanical and osteoinductive properties (i.e.
    Type: Grant
    Filed: April 13, 2018
    Date of Patent: November 2, 2021
    Assignees: SEPTODONT OU SEPTODONT SAS OU SPECIALITES SEPTODONT, UNIVERSITE DE PARIS, INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), SORBONNE UNIVERSITE, ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS
    Inventors: Fleur Beres, Gilles Richard, Arnaud Dessombz, Stéphane Simon, Juliane Isaac
  • Lipid particle composition and pharmaceutical composition
    Patent number: 11154534
    Abstract: An object of the present invention is to provide a lipid particle composition containing panobinostat or a salt thereof and exhibiting a high bone marrow-targeting capability, and a pharmaceutical composition including the lipid particle composition. According to the present invention, provided is a lipid particle composition containing panobinostat or a salt thereof, in which a lipid particle contains a phospholipid and cholesterol.
    Type: Grant
    Filed: June 21, 2019
    Date of Patent: October 26, 2021
    Assignee: FUJIFILM Corporation
    Inventors: Yuta Yoshino, Hayato Ogura, Mikinaga Mori, Taisuke Endo, Kentaro Numajiri, Ritsuko Hori
  • Lecithin vesicles for oral delivery
    Patent number: 11154502
    Abstract: Giant multi-lamellar vesicles (GMVs) comprising lecithin are provided which are at least about 3 ?m in size. Methods for preparing the GMVs, and for preparing large unilamellar vesicles (LUVs) from the GMVs, are provided, as well as methods for encapsulating cargo within the GMVs and LUVs. The present vesicles are useful for the oral delivery of encapsulated cargo.
    Type: Grant
    Filed: January 24, 2019
    Date of Patent: October 26, 2021
    Assignee: CannaClear Inc.
    Inventor: Alejandro Marangoni
  • Sintered nanoparticles and use of the same against a virus
    Patent number: 11141382
    Abstract: A composition includes sintered nanoparticles prepared by sintering a chelate of ferrous ions with an amino acid. The sintered nanoparticles have an average particle diameter ranging from 10 to 400 nm as determined by Electron Probe X-ray Micro-Analyzer. Also disclosed herein are a method for inhibiting and/or killing a virus in a subject and applications of such method. The method includes administering to the subject the composition.
    Type: Grant
    Filed: December 27, 2019
    Date of Patent: October 12, 2021
    Assignee: PROFEAT BIOTECHNOLOGY CO., LTD.
    Inventors: Tsun-Yuan Lin, Mu-Kuei Chen, Kai-Ting Wang, Hsun-Jin Jan
  • Nanoemulsions comprising glycerol in aqueous phase
    Patent number: 11141362
    Abstract: The present invention relates to novel oil-in-water nanoemulsions. The oil phase contains oil selected from the group consisting of triglyceride oil and/or petrolatum as well as C8 to C18 fatty acid; and the aqueous phase contains specific N-acyl derivatives having specific counterions of amino acid salt as emulsifier, glycerol, and water. When (i) there is defined ratio of glycerol to water; (ii) specific counterion for amino acid surfactant and (iii) fatty acid in oil phase. Nanoemulsions are processed in a one-step process yielding droplets of size 20 to 400 nm. In one embodiment, droplets of size 20 to 400 nm can be made using rotor-stator device (in one-step process) and in the absence of pressure based homogenizer. This saves in energy and cost. Compositions prepared according to this processes are also contemplated.
    Type: Grant
    Filed: January 4, 2018
    Date of Patent: October 12, 2021
    Assignee: CONOPCO, INC.
    Inventor: Congling Quan
  • Low water dentifrice compositions
    Patent number: 11135144
    Abstract: The present disclosure provides low water dentifrice compositions comprising an effective amount of a zinc ion source, a tin ion source, a polyphosphate and an acid. The acid lowers the pH of the composition to enable stabilization of the metal ions and extend shelf-life of the composition.
    Type: Grant
    Filed: December 26, 2014
    Date of Patent: October 5, 2021
    Assignee: Colgate-Palmolive Company
    Inventors: Kavita Vemishetti, Linh Fruge, Michael Prencipe
  • Specially formulated compositions of inhaled nintedanib and nintedanib salts
    Patent number: 11123290
    Abstract: Disclosed herein are formulations of nintedanib and salts thereof, indolinone derivative compounds and salts thereof for aerosolization and use of such formulations for the prevention or treatment of various fibrotic, carcinogenic, vascular and viral infectious diseases, including diseases associated with the lung, heart, kidney, liver, eye, central nervous system and surgical sites. Formulations and delivery options described herein allow for efficacious local delivery of nintedanib or a indolinone derivative compound or salt thereof. Methods include inhalation procedures, indications and manufacturing processes for production and use of the compositions described. Also included are methods for identifying compounds and indications that benefit by reformulation and inhalation administration.
    Type: Grant
    Filed: August 22, 2019
    Date of Patent: September 21, 2021
    Assignee: AVALYN PHARMA INC.
    Inventors: Mark William Surber, Stephen Pham
  • Inhibitors of intracellular invasion
    Patent number: 11123333
    Abstract: The disclosure provides compounds that inhibit the invasion of host cells by intracellular parasites. These find use, for example, in treating and preventing periodontitis or a periodontitis-related condition or symptom.
    Type: Grant
    Filed: February 17, 2019
    Date of Patent: September 21, 2021
    Assignees: Meharry Medical College, Duke University
    Inventors: Hua Xie, Chin-Ho Chen
  • Methods and devices for repair of severed peripheral nerves with erythropoietin
    Patent number: 11116876
    Abstract: An implantable drug-delivery device for repairing a severed peripheral nerve. The drug-delivery device includes a matrix formed of a biopolymer and an erythropoietin (EPO) entrapped in the matrix. After in vivo implantation of the drug-delivery device, the EPO elutes over a period of 1 day to 12 weeks. Also disclosed is a method for repairing a severed peripheral nerve using the implantable drug-delivery device.
    Type: Grant
    Filed: February 20, 2019
    Date of Patent: September 14, 2021
    Assignee: Shu-Tung and Alice Li Foundation Inc.
    Inventor: Shu-Tung Li
  • Electrospun PNIPAAm/PCL fiber mats for aligned cell sheets
    Patent number: 11111611
    Abstract: The present invention provides compositions comprising aligned fibers of electrospun PNIPAAm and poly (?-caprolactone) (PCL) (denoted PNIPAAm/PCL fibers). The PNIPAAm/PCL compositions enable enhanced growth and detachment of intact anisotropic cell sheets. The compositions do not require chemical modification or resource-intensive techniques, thus saving time and expense, and have the potential to generate tissue-specific, aligned cell sheets for transplant studies.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: September 7, 2021
    Assignee: Board of Regents, The University of Texas System
    Inventors: Janeta Zoldan, Alicia Allen
  • Sintered ferrous amino acid particles and use of the same against a virus
    Patent number: 11110065
    Abstract: A composition includes sintered ferrous amino acid particles prepared by sintering a ferrous amino acid chelate which includes ferrous ions and an amino acid. The sintered ferrous amino acid particles have an average particle size ranging from 500 to 2600 nm and a weight average molecular weight ranging from 1,500 Dalton to 600,000 Dalton. Also disclosed herein are a method for inhibiting and/or killing a virus in a subject and applications of such method. The method includes administering to the subject the composition.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: September 7, 2021
    Assignee: PROFEAT BIOTECHNOLOGY CO., LTD.
    Inventors: Tsun-Yuan Lin, Mu-Kuei Chen, Kai-Ting Wang, Hsun-Jin Jan
  • Antimicrobials and methods of use thereof
    Patent number: 11103471
    Abstract: This disclosure provides generally for antimicrobial compositions and methods of use comprising an anthocyanin, an anthocyanidin or metabolites thereof. Methods for promoting healing of a wound using these compositions are also disclosed. These compositions have broad spectrum antimicrobial activity and are safe for human and animal uses. Further, these compositions are safe for medical uses and industrial uses as antiseptic preparations to reduce or prevent microbial growth, including killing bacterial biofilms.
    Type: Grant
    Filed: March 18, 2020
    Date of Patent: August 31, 2021
    Inventor: Lanny Leo Johnson
  • Lipids for therapeutic agent delivery formulations
    Patent number: 11103583
    Abstract: The description is directed to ionizable lipids useful for enhancing the delivery of therapeutic agents in liposomes.
    Type: Grant
    Filed: July 2, 2019
    Date of Patent: August 31, 2021
    Assignee: Nitto Denko Corporation
    Inventors: Joseph E. Payne, John A. Gaudette, Zheng Hou, Mohammad Ahmadian, Lei Yu, Victor Knopov, Violetta Akopian, Priya Karmali, Richard P. Witte, Neda Safarzadeh, Wenbin Ying, Jun Zhang
  • Hybrid muco-adhesive delivery systems and use thereof
    Patent number: 11096891
    Abstract: A composition and method for the administration of therapeutic and/or diagnostic agents is provided. Specifically, a hybrid system, composed of polymer that harbors drug-loaded lipid nanoparticles, and use thereof for the administration of active agents e.g., anti-cancer agents, is provided.
    Type: Grant
    Filed: June 21, 2017
    Date of Patent: August 24, 2021
    Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
    Inventors: Havazelet Bianco-Peled, Avi Schroeder, Shlomit Avidan-Shlomovich, Yarden Degani, Mor Goldfeder
  • Oral care composition
    Patent number: 11090243
    Abstract: An oral care composition, including a non-aqueous dispersant and an amphiphilic copolymer structure-building agent.
    Type: Grant
    Filed: December 20, 2019
    Date of Patent: August 17, 2021
    Assignee: Colgate-Palmolive Company
    Inventors: Shaotang Yuan, Guofeng Xu, Robert DiCosimo, Sharon L. Haynie