Patents Examined by Chris R Tate
  • Patent number: 10166270
    Abstract: The present invention discloses a composition and method for effecting various cytokines and NF-?B by administering an effective amount of a phyto-percolate composition to an individual. In various exemplary embodiments, the composition is claimed to be useful for the effective treatment of inflammation, cancer, and/or various infections including HIV by regulation of various interleukins, such as IL-10 and IL-2, and of transcription factors including NF-?B.
    Type: Grant
    Filed: December 2, 2014
    Date of Patent: January 1, 2019
    Assignee: Zivo Bioscience, Inc.
    Inventors: Tiffany Thomas, Fazlul Sarkar, Denis Callewaert, Andrew Dahl, Enrique Martinez
  • Patent number: 10118827
    Abstract: The invention relates to a synthetic bone material and a process for making the same. The synthetic bone material may comprise multiple phases of calcium phosphate. Another aspect of the invention is a porous filter, and the method of making the same, and wherein the porous filter is substantially similar to the process for forming the synthetic bone material.
    Type: Grant
    Filed: May 12, 2014
    Date of Patent: November 6, 2018
    Inventors: Reed A. Ayers, Nina L. Vollmer
  • Patent number: 10111910
    Abstract: Described herein are compositions and methods of treating a cardiac condition using modified placental tissue or an extract of a placental tissue, capable of recruiting stem cells or promoting healing in vivo and in vitro.
    Type: Grant
    Filed: January 17, 2014
    Date of Patent: October 30, 2018
    Assignee: MiMedx Group, Inc.
    Inventors: Thomas J. Koob, Hubbard Frank Burrows, III
  • Patent number: 10086029
    Abstract: The present disclosure concerns plant extracts which have been fermented with kefir grains, methods of production of these extracts, a powder comprising these extracts and compositions comprising these extracts. Since these extracts have a high content of aglycone active principles, their biological activities are high and their applications are varied.
    Type: Grant
    Filed: April 20, 2015
    Date of Patent: October 2, 2018
    Assignee: KEFIPLANT INC.
    Inventors: Chantale Houle, Serge Rollan, Christian Deshayes
  • Patent number: 10076550
    Abstract: The present invention relates to a mainly herbal composition comprising Terminalia bellerica fruits (1-5% w/w) more particularly the extract of dried fruits. The composition further has exogenously added malonic acid, glutamic acid, eicosenoic acid and linolenic acid. The composition of present invention is useful in treatment and control of gastro intestinal problems like diarrhea, dysentery, ulcers etc. and used as an oral dosage form.
    Type: Grant
    Filed: November 19, 2014
    Date of Patent: September 18, 2018
    Inventors: Garima Pandey, Chandana Venkateswara Rao, Om Prakash Sidhu, Ajay Kumar Singh Rawat, Chandra Shekhar Nautiyal
  • Patent number: 10076527
    Abstract: The present invention refers to a medicament which activates gastrointestinal movement. The medicament consists essentially of Cucurbitacin D and one or more substances form the group including Cucurbitacin A, Cucurbitacin B, Cucurbitacin E, Isocucurbitacin B and Isocucurbitacin D. The medicament is made from an extract obtained from Muskmelon Base, the fruit stem of Cucumis melo L. The medicament can promote enterokinesia in both normal animals and in animal models where gastrointestinal movement is inhibited. It has also been demonstrated to activate the movements of the stomach, small and large intestines. The extract may be used alone or in combination with the other botanical ingredients or chemical substances to form the pharmaceutical preparation.
    Type: Grant
    Filed: June 10, 2015
    Date of Patent: September 18, 2018
    Assignee: Botanic Century (Beijing) Co., Ltd.
    Inventors: Chen Xie, Xiuzhen Luo, Yun Qi
  • Patent number: 10071049
    Abstract: Compositions for reducing skin aging are disclosed herein. The compositions can be topically applied to a skin region to reduce or prevent skin wrinkles, fine lines, thinning skin, sagging skin, skin dryness, and skin itchiness.
    Type: Grant
    Filed: April 30, 2014
    Date of Patent: September 11, 2018
    Assignee: Kimberly-Clark Worldwide, Inc.
    Inventors: Scott W. Wenzel, David J. Tyrrell, Alencia Vanay Grice, Stephanie VandeVen Teat
  • Patent number: 10040833
    Abstract: The present invention relates to fermentation processes. The objective of the invention was to provide methods for producing nisin containing ferments and formulating such ferments into preservatives. It was in particular an object of the present invention to provide improved processes for producing nisin containing ferments by simple and efficient (batch) culturing and allowing for simple down-stream processing either into a liquid, semi-liquid or a dry powder product, having sufficient nisin content and stability, good handling properties and satisfactory organoleptic properties. Such processes are provided, as well as the products that can be obtained with it and their use.
    Type: Grant
    Filed: January 15, 2014
    Date of Patent: August 7, 2018
    Assignee: PURAC BIOCHEM B.V.
    Inventors: Arne Olav Sliekers, Jasper Meijer, Diana Visser
  • Patent number: 10039877
    Abstract: Methods and systems for obtaining platelets are disclosed. Platelets are collected in a pre-determined volume of plasma and a determined amount of a combined storage medium including the pre-determined amount of plasma and a volume of a synthetic additive solution.
    Type: Grant
    Filed: August 23, 2013
    Date of Patent: August 7, 2018
    Assignee: FENWAL, INC.
    Inventors: Katherine Radwanski, Kyungyoon Min
  • Patent number: 10028970
    Abstract: The invention concerns a cashew apple extract and a composition comprising a cashew apple extract and optionally a carrier, in particular for use for allowing reduction of body weight gain or limitation of increasing body weight, reduction or limitation of fat storage, of fatty liver, of liver triglycerides level, of hypertriglyceridemia, of glycemia level, of insulinemia, of insulin resistance, and/or of one or several factors of metabolic syndrome.
    Type: Grant
    Filed: June 7, 2012
    Date of Patent: July 24, 2018
    Assignee: NATUREX
    Inventors: Nicolas Chapal, Max Reynes, Vickram Beejmohun, Manuel Dornier
  • Patent number: 10028988
    Abstract: Synthesis of Nuxia oppositifolia nanoparticles includes providing an extract of Nuxia oppositifolia, dissolving the extract in alcohol to provide a mixture, adding water to the mixture to provide an aqueous solution, adding an acidic solution to the aqueous solution to form a final solution including Nuxia oppositifolia nanoparticles; and centrifuging the final solution to isolate the Nuxia oppositifolia nanoparticles.
    Type: Grant
    Filed: June 1, 2017
    Date of Patent: July 24, 2018
    Inventors: Manal Ahmed Gasmelseed Awad, Rabab Abd El Moneim Khalil El Dib, Shaza Mohamed Adel Al-Massarani, Ali Ali El-Gamal
  • Patent number: 10017797
    Abstract: The present invention discloses a novel method for biological reduction of the carboxylic acids to their corresponding aldehydes and/or alcohols with high productivity and high yield by using fungus in the category of basidiomycetes. This reduction is specific and selective for its functional group (—COOH), without affecting other functional group such as—R groups (—OH, —NH2, -alkyl, -alkyoxy) and their position, number on aromatic ring. The method of the invention relates to reduction of aryl acids to aldehyde and/or alcohols by employing a white rot fungus—Pycnoporus cinnabarinus, an organism of basidiomycete species, grown in vessel/column. The biotransformation was performed in vessel/column/fermentor with pH control, dissolved oxygen, membrane system, product extractor is attached.
    Type: Grant
    Filed: August 28, 2013
    Date of Patent: July 10, 2018
    Inventors: Mahendra M Yeole, Arvind M. Lali
  • Patent number: 10016474
    Abstract: An extract from leaves of mulberry is disclosed. The extract has an IC50 value sufficient to inhibit ?-glucosidase I. The extract may comprise 5-40% (w/w) total imino sugars and 20-70% (w/w) total amino acids. The extract may reduce the production of melanin for the treatment of such ailments or diseases caused by pigmentation as freckle, chloasma, striae gravidarum, sensile plaque and melanoma. The extract may also control blood glucose level.
    Type: Grant
    Filed: February 12, 2015
    Date of Patent: July 10, 2018
    Assignee: Botanic Century Beijing Co. Ltd.
    Inventors: Chen Xie, Yingshu Zou
  • Patent number: 10010564
    Abstract: The present invention relates to a novel pharmaceutical composition with milk of immunized camelid, particularly Camelus dromedarius as the main component (i.e. active ingredient) and a method for the treatment or prevention of skin or mucus membrane infections, particularly Acne vulgaris. The present invention also discloses a process of preparing said composition.
    Type: Grant
    Filed: September 11, 2012
    Date of Patent: July 3, 2018
    Inventors: Khaled Mahmood Al-Qaoud, Penelope Agmad Shihab, Luay Fawzi Abu-Oatousch, Christopher R. Lowe
  • Patent number: 10004827
    Abstract: Provided are methods for preparing gelled, solubilized extracellular matrix (ECM) compositions useful as cell growth scaffolds. Also provided are compositions prepared according to the methods as well as uses for the compositions. In one embodiment a device, such as a prosthesis, is provided which comprises an inorganic matrix into which the gelled, solubilized ECM is dispersed to facilitate in-growth of cells into the ECM and thus adaptation and/or attachment of the device to a patient.
    Type: Grant
    Filed: February 18, 2014
    Date of Patent: June 26, 2018
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Stephen F. Badylak, Donald Freytes
  • Patent number: 10004772
    Abstract: The subject invention provides compositions and methods for treating human dermatological conditions by employing a microbiome-centered treatment approach. Preferred embodiments of the invention provide pharmaceutical and cosmetic compositions, and the methods of using the same, comprising a strain of Lactobacillus fermentum bacterium, or bioactive extracts thereof, derived from human microbiota and capable of growing in biofilm phenotype.
    Type: Grant
    Filed: April 25, 2017
    Date of Patent: June 26, 2018
    Inventors: Eva A. Berkes, Nicholas T. Monsul, Frederick T. Boehm
  • Patent number: 9999643
    Abstract: A therapeutic composition for wet and dry gangrene includes an herbal composition alone, or in combination with one or more animal-derived products. The herbal composition can include a mixture of Saussurea acrophila Diels, Saussurea ceratocarpa, and Aucklandia lappa Decne. The mixture can include, for example, a mixture of extracts or whole herbs of Saussurea acrophila Diels, Saussurea ceratocarpa, and Aucklandia lappa Decne. The one or more animal-derived products can include at least one of camel milk and camel saliva.
    Type: Grant
    Filed: October 16, 2017
    Date of Patent: June 19, 2018
    Inventors: Sidgi Syed Anwer Abdo Hasson, Ali A. H. Al-Jabri
  • Patent number: 9999589
    Abstract: Provided are a culture medium of an adipose-derived stem cell, a method for preparing the same, and a composition for promoting hair growth, in which the composition includes the culture medium. The adipose-derived stem cell (ADSC-T) according to the present invention exhibits long lifespan, improved cell proliferation rate, and extended proliferation period, as compared with a primary adipose-derived stem cell (ADSC), and thus, the adipose-derived stem cell (ADSC-T) can be usefully used for the study about the adipose-derived stem cell and the mass production of the culture medium of the adipose-derived stem cell. In addition, according to the present invention, the culture medium of the adipose-derived stem cell (ADSC-T) that expresses a T antigen of SV40 exhibits excellent hair growth effectiveness and can be usefully used as a raw material for the hair loss prevention and hair growing agents.
    Type: Grant
    Filed: August 29, 2012
    Date of Patent: June 19, 2018
    Inventors: Dong Wan Kim, Mi Jung Seo, Gwang Lee, Woo Hong Joo, Sun Hee Kim
  • Patent number: 9993505
    Abstract: Methods of generating an innervated muscle structures are disclosed as well as bioengineered structures for tissue repair or regeneration. The methods can include the steps of obtaining populations of smooth muscle cells and neuronal progenitor cells and then seeding the cells together onto a matrix material, followed by culturing the seeded cells to form an innervated smooth muscle cell construct of directionally oriented smooth muscle cells. In one embodiment, the neuronal progenitor cells can be seeded first as neurospheres in a biocompatible solution, e.g., a collagen/laminin solution, and allowed to gel. Next, a second suspension of smooth muscle cells can be deposited as separate layer. Multiple layer structures of alternating muscle or neuron composition can also be formed in this manner. Differentiation of the neuronal progenitor cells can be induced by exposure to a differentiation medium, such as Neurobasal A medium and/or exposure to a differentiating agent, such as B-27 supplement.
    Type: Grant
    Filed: January 31, 2013
    Date of Patent: June 12, 2018
    Assignee: Wake Forest University Health Sciences
    Inventor: Khalil Bitar
  • Patent number: 9987318
    Abstract: An anti-inflammatory composition for inhibiting the secretion of cytokines, with the composition being based on a decoction of papaya leaves, a method of obtaining such a composition and a method of manufacturing an anti-inflammatory remedy for inhibiting cytokine secretion, having the composition the anti-inflammatory composition as its active principle. The method of obtaining the composition includes the steps of producing a decoction from papaya leaves, filtering the decoction in order to obtain a filtrate and atomizing the filtrate.
    Type: Grant
    Filed: April 2, 2012
    Date of Patent: June 5, 2018
    Assignee: Esprit D'Ethique
    Inventor: Christophe Binachon