Patents Examined by Chris R Tate
  • Patent number: 9913929
    Abstract: A method of preparing a bone graft. Mixing bone marrow aspirate with an effective amount of a binding reagent that is capable of binding with red blood cells in the bone marrow aspirate. The bound red blood cells are aggregated. The aggregated bound red blood cells are separated from the bone marrow aspirate to provide a supernatant. At least a portion of the supernatant is associated with an osteoconductive matrix to form the bone graft.
    Type: Grant
    Filed: October 17, 2014
    Date of Patent: March 13, 2018
    Assignee: Fortus Medical, Inc.
    Inventor: Robert Assell
  • Patent number: 9913870
    Abstract: The subject invention pertains to supercritical carbon dioxide extracts of Commiphora mukul resin (guggul), which can be modified or not modified by some ethanol addition; methods for their production; and methods of use, such as inhibiting HMG-CoA reductase, inhibiting transformation of pre-adipocytes to adipocytes, inhibiting triglyceride storage, promoting insulin sensitivity in adipocytes, treatment of disorders (for example, hypercholesterolemia, hyperlipidemia, hyperglycemia, obesity, metabolic syndrome, cardiovascular disease, atherosclerotic heart disease, autoimmune disorder, insulin resistance, leptin resistance, arthritis, cell proliferation disorder, such as cancer and atherosclerosis; damaged skin, sores, cuts, rashes, bruises, dryness, burns, sunburn, radiation burn, and infection), and regulating or suppressing appetite.
    Type: Grant
    Filed: January 11, 2013
    Date of Patent: March 13, 2018
    Assignees: DHARMA BIOMEDICAL, LLC, FLAVEX NATUREXTRAKTE GMBH
    Inventors: Steven J. Melnick, Karl-Werner Quirin, Cheppail Ramachandran, Melvin Rothberg
  • Patent number: 9913867
    Abstract: The present invention relates to a composition comprising an extract of a mixture of Undaria pinnatifida sporophylls and ascidian shells for treating atopic dermatitis, wherein the composition has the excellent effect of treating atopic dermatitis through the synergistic interaction of the anti-inflammatory effect of Undaria pinnatifida sporophylls and the cell regenerative effect of ascidian shells. The composition of the invention is not involved in the suppression of cytokine production. However, it is assumed that the composition has the effects of suppressing inflammation as well as regenerating skin.
    Type: Grant
    Filed: October 31, 2012
    Date of Patent: March 13, 2018
    Assignee: INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY
    Inventors: Beyong-dae Choi, Seong-hun Jeong, Shi-hyang Park, Myung-sook Kim, Soon-ok Choi
  • Patent number: 9907882
    Abstract: Methods of making and osteoinductive compositions are provided. The method includes mixing isolated periosteum tissue with a demineralized bone matrix to form the osteoinductive composition. The periosteum tissue is isolated from the surface of large bones such as femur, tibia, humerus or a mixture thereof. The demineralized bone matrix can include a plurality of surface demineralized or fully demineralized bone fibers, bone chips, bone particles or mixtures thereof. In the osteoinductive composition the substantially isolated periosteum tissue is from about 0.5% wt. to about 10% wt. A method for repairing a bone defect is also provided. The method of treatment includes applying to the bone defect a substantially effective amount of a mixture of isolated periosteum tissue and demineralized bone matrix.
    Type: Grant
    Filed: April 18, 2014
    Date of Patent: March 6, 2018
    Assignee: Warsaw Orthopedic, Inc.
    Inventor: William F. McKay
  • Patent number: 9907827
    Abstract: The present invention refers to a prebiotic mixture comprising at least one plant polysaccharide fiber and at least one of Propolis and/or Olea europaea and/or Aloe vera extracts, optionally comprising also Thymus vulgaris and/or Agrimonia eupatoria extracts. Moreover, the present invention also relates to said mixture for use in the preservation and/or in the restoration of the intestinal microbiota balance.
    Type: Grant
    Filed: March 7, 2013
    Date of Patent: March 6, 2018
    Assignee: ABOCA S.P.A. SOCIETÁ AGRICOLA
    Inventors: Valentino Mercati, Valentina Mercati, Andrea Lugli, Anna Maidecchi
  • Patent number: 9901608
    Abstract: Disclosed is a composition for enhancing alcohol metabolism in a subject, who overdrank, the composition comprises an effective amount of ginsenoside-free extract of steam-dried Korean ginseng berry (GFM) and one or more pharmaceutically or sitologically acceptable carriers. The composition of the present disclosure may be effective for alleviating hangover according to overdrink and for protecting liver from alcoholic injure.
    Type: Grant
    Filed: August 28, 2014
    Date of Patent: February 27, 2018
    Assignee: GANGNEUNG-WONJU NATIONAL UNIVERSITY INDUSTRY ACADEMY COOPERATION GROUP
    Inventor: Seong-Soo Joo
  • Patent number: 9901591
    Abstract: Disclosed are methods and preparations useful for reducing fat at a targeted area(s) on a human. The preparations comprise as an active ingredient an adipolysis enhancing (i.e., fat-melting) amount of an active ingredient, paeoniflorin (PF). The preparations may be provided as an injectable preparation or as a topically applied preparation, such as in the form of a crème or lotion. In topical preparations, the active ingredient paeoniflorin may be contained within nanospheres, such as albumin nanospheres. The PF-containing preparations may also include a permeant, such as azone. The method may be accompanied by the application of ultrasound to the area being treated prior to, during or after, or prior to, during, and after application of the paeoniflorin preparation to an area of the body in which fat reduction is desired.
    Type: Grant
    Filed: July 10, 2013
    Date of Patent: February 27, 2018
    Inventor: Bakr Rabie
  • Patent number: 9901600
    Abstract: The invention provides compositions comprising mesenchymal stem cell (MSC) derived exosomes, and methods of their use in subjects having certain lung diseases including inflammatory lung disease.
    Type: Grant
    Filed: March 9, 2012
    Date of Patent: February 27, 2018
    Assignee: Children's Medical Center Corporation
    Inventors: S. Alexander Mitsialis, Changjin Lee, Stella Kourembanas
  • Patent number: 9901610
    Abstract: Disclosed are compositions containing: a) Phaseolus vulgaris extract; b) Cynara scolymus extract; c) Echinacea angustifolia extract; d) Vitis vinifera extract and optionally e) Panax ginseng extract, mixed with suitable excipients.
    Type: Grant
    Filed: October 10, 2013
    Date of Patent: February 27, 2018
    Assignee: INDENA S.P.A.
    Inventors: Ezio Bombardelli, Fabrizio Corti
  • Patent number: 9901843
    Abstract: A method of capturing a vaporized component or components, and apparatus for same is provided. The method involves vaporization of desired components, and capture of the vaporized components in a material using a vapor trap device. Once captured, the material with the component stored therein may be used for any number of purposes including ingestion, topical administration, and/or aromatization.
    Type: Grant
    Filed: May 5, 2017
    Date of Patent: February 27, 2018
    Inventor: Geoff Todosiev
  • Patent number: 9895405
    Abstract: Present invention relates to a use of Radix Salviae Miltiorrhizae (Danshen) or its preparations in preparation of drugs for treating disease related to hepatic fibrosis.
    Type: Grant
    Filed: January 4, 2013
    Date of Patent: February 20, 2018
    Assignee: TASLY PHARMACEUTICAL GROUP CO., LTD.
    Inventors: Yonghong Zhu, Jinfang Hu, Jie Ma, Xiuping Shen
  • Patent number: 9895421
    Abstract: The present invention relates to a pharmaceutical composition, which contains a mixture of extracts of Stemonae Radix, Asparagi Tuber, Scutellariae Radix, Schisandrae Fructus, Rehmanniae Radix Preparata, Armeniacae Semen, and Moutan Cortex Radicis, for suppressing the occurrence of inflammatory bowel diseases due to cigarette smoke, a method for preventing or treating inflammatory bowel diseases, a method for suppressing the expression of inflammatory cytokines by using the composition, and to a food composition, which contains a mixture of extracts of Stemonae Radix, Asparagi Tuber, Scutellariae Radix, Schisandrae Fructus, Rehmanniae Radix Preparata, Armeniacae Semen, and Moutan Cortex Radicis, for preventing or ameliorating inflammatory bowel diseases due to cigarette smoke.
    Type: Grant
    Filed: July 3, 2013
    Date of Patent: February 20, 2018
    Assignee: University-Industry Cooperation Group of Kyung Hee University
    Inventors: Jin Ju Kim, Eun Jung Ko, Eui Jeoung Lee
  • Patent number: 9896643
    Abstract: Methods and systems for recovering a desired co-product from a feedstock to ethanol production process are provided. The methods involve a multi-step separation of a fermentation-derived feedstock, in which an initial separation produces a discharge stream and an output feed stream including the co-product, and a final separation further purifies the output feed stream while also producing a recycle stream that is reintroduced into the separation process. The systems include at least an initial and at least a final separation device which are in fluid communication in both upstream and downstream directions. The initial separation device separates at least a portion of a non-co-product containing phase from a feed stream comprising the non-co-product containing phase and a co-product containing phase, and the final separation device separates at least a portion of the co-product containing phase from a stream comprising the co-product containing phase and a non-co-product containing phase.
    Type: Grant
    Filed: January 16, 2014
    Date of Patent: February 20, 2018
    Assignee: POET RESEARCH, INC.
    Inventor: Steven Redford
  • Patent number: 9896656
    Abstract: Differentiation and stability of neural stem cells can be enhanced by in vitro or in vivo culturing with one or more extracellular matrix (ECM) compositions, such as collagen I, IV, laminin and/or a heparan sulfate proteoglycan. In one aspect of the invention, adult mammalian enteric neuronal progenitor cells can be induced to differentiate on various substrates derived from components or combinations of neural ECM compositions. Collagen I and IV supported neuronal differentiation and extensive glial differentiation individually and in combination. Addition of laminin or heparan sulfate to collagen substrates unexpectedly improved neuronal differentiation, increasing neuron number, branching of neuronal processes, and initiation of neuronal network formation. In another aspect, neuronal subtype differentiation was affected by varying ECM compositions in hydrogels overlaid on intestinal smooth muscle sheets.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: February 20, 2018
    Assignee: Wake Forest University Health Sciences
    Inventor: Khalil Bitar
  • Patent number: 9896712
    Abstract: The present disclosure relates to biosensing systems and biosensing elements having increased storage capability and increased functional lifetimes through using compositions and methods for recycling cofactors.
    Type: Grant
    Filed: October 6, 2015
    Date of Patent: February 20, 2018
    Assignee: Colorado State University Research Foundation
    Inventor: Kenneth F. Reardon
  • Patent number: 9889170
    Abstract: A method of preparing nanoparticles from desert date can include providing a metal salt solution comprising metal ions; providing desert date extract solution that comprises a reducing agent, and combining the metal ion solution and the desert date extract solution while stirring at a temperature in the range of 25° C. to 100° C. to produce metal or metal oxide nanoparticles. The metal nanoparticles can be gold nanoparticles. The metal oxide nanoparticles can be zinc oxide nanoparticles. The nanoparticles can be used to inhibit the growth or proliferation of a cancer cell and/or microorganisms.
    Type: Grant
    Filed: October 6, 2016
    Date of Patent: February 13, 2018
    Assignee: KING SAUD UNIVERSITY
    Inventors: Manal Ahmed Gasmelseed Awad, Rabab Abd El Moneim Khalil El Dib, Awatif Ahmed Hendi, Shaza Mohamed Adel Al-Massarani, Khalid Mustafa Osman Ortashi
  • Patent number: 9889173
    Abstract: The present invention provides a composition for improving macular pigment optical density and preventing or treating age-related macular optical degeneration. The composition comprises lutein, zeaxanthin and tea extracts, wherein the weight ratio of zeaxanthin to lutein is more than or equal to 1. The composition may prevent formation of choroidal neovascularization to achieve effects on comprehensively preventing or treating age-related macular optical degeneration (AMD).
    Type: Grant
    Filed: August 8, 2013
    Date of Patent: February 13, 2018
    Assignee: Zhejiang Medicine Co., Ltd. Xinchang Pharmaceutical Factory
    Inventors: Xinde Xu, Lihua Zhang, Xiaoxia Sun
  • Patent number: 9884006
    Abstract: A cosmetic composition comprises a coffee cherry preparation, and most preferably an extract from a sub-ripe quick-dried coffee cherry. Particularly contemplated cosmetic compositions are formulated as a shampoo, lotion, cream, balm, or ointment, and will have at least one of an antioxidant effect, an anti-inflammatory effect, a UV-protective effect, an antimutagenic effect, a chemoprotective effect, a scar reducing effect, a skin-lightening effect, a moisturizing effect, a wrinkle reduction effect, and an antibacterial effect.
    Type: Grant
    Filed: September 26, 2011
    Date of Patent: February 6, 2018
    Assignee: VDF Futureceuticals, Inc.
    Inventor: Dusan Miljkovic
  • Patent number: 9884083
    Abstract: Compositions are provided that include date palm pollen or an extract thereof. The compositions may be formulated use in methods of treatment or prophylaxis of inflammatory conditions such as adverse side effects of anti-cancer treatment or stomatitis conditions.
    Type: Grant
    Filed: June 9, 2014
    Date of Patent: February 6, 2018
    Assignee: ClinAvenir, LLC
    Inventors: Rashad Tawashi, Mona Tawashi
  • Patent number: 9885068
    Abstract: The disclosed subject matter relates generally to a method for modifying oil, and specifically to a process for increasing the concentration of polyunsaturated fatty acid in an oil composition.
    Type: Grant
    Filed: March 8, 2013
    Date of Patent: February 6, 2018
    Assignee: DSM IP Assets B.V.
    Inventors: Jaroslav A. Kralovec, Weijie Wang, James Colin Barrow