Abstract: A method can classify cervical accelerometry data acquired for a swallowing event to identify a possible swallowing impairment in a candidate. The method can include receiving axis-specific vibrational data for an anterior-posterior (A-P) axis and a superior-inferior (S-I) axis and representative of the swallowing event, for example from an accelerometer operatively coupled to a processing module that is a local or remote computing device. The method can include extracting one or more specific meta-features from the data and then outputting from the processing module a classification of the swallowing event based on the extracted meta-features, for example a first classification indicative of normal swallowing or a second classification indicative of possibly impaired swallowing.

Abstract: Described herein are a computer enhanced medical method and device for generating an asthmatic condition indication. The apparatus receives a lung signal from a stethoscope, the lung signal having been converted from an analog signal to a digital signal. Furthermore, circuitry included in the apparatus performs, inter alia, the following: displays a patient recording canvas corresponding to physical locations on a body of the patient, the canvas including an anterior patient orientation and a posterior patient orientation, generates a recording process, the recording process including recording, for a predetermined period of time, the detected lung signal, and associates the recording with a marked location. Furthermore, the circuitry merges the recorded lung signal from each marked location on the patent recording canvas as merged information, and applies processing to the merged information to generate the asthmatic condition indication.

Abstract: This document discusses, among other things, systems and methods to compensate for the effects of temperature on sensors, such as analyte sensor. An example method may include determining a temperature-compensated glucose concentration level by receiving a temperature signal indicative of a temperature parameter of an external component, receiving a glucose signal indicative of an in vivo glucose concentration level, and determining a compensated glucose concentration level based on the glucose signal, the temperature signal, and a delay parameter.

Abstract: The sensor includes a working electrode having a first wire with a first flat surface and an electrochemical element on the first flat surface. A reference electrode includes a second wire with a second flat surface and a counter electrode includes a third wire with a third flat surface. The first wire is a first sensor wire for the working electrode, the second wire is a second sensor wire for the reference electrode and the third wire is a third sensor wire for the counter electrode in a plurality of sensor wires. The second flat surface and the third flat surface face toward each other.

Abstract: A method of calibrating an analyte measurement system is provided.

Abstract: Provided herein are microelectrodes and methods of localizing and targeting the same. The microelectrodes include electrochemical or biological sensors, an array of electrical contacts along a long axis of the microelectrode, or both. The methods of localizing and targeting use statistical manipulations to reduce the errors inherent in spike train analyses.

Abstract: A middle ear sound transmission characteristics evaluation system includes a probe; a measuring probe that includes an actuator that vibrates the probe and a force sensor that outputs a voltage in accordance with a reaction force exerted to the actuator when a tip of the probe is brought into contact with ossicles; an electrode that is installed on or near a round window and detects a potential value of a cochlear microphonic when vibration is applied to the ossicles by the probe; a database that stores a sensor voltage value output by the force sensor before surgical treatment, the potential value detected by the electrode, and surgical details; and a surgical details proposing unit that proposes selected surgical details on the basis of the magnitude of at least one of the sensor voltage value and the potential value measured before surgery with reference to the database.

Abstract: An apparatus includes a body and an actuator is coupled to the body. A needle is mounted to the actuator. The needle comprises a slot along a length to a tip. A sensor is coupled to a plurality of wires. A base is configured to be moveable by the actuator and includes a cutout, a circuit board having a microprocessor, and a plurality of contacts. Each contact is coupled to a wire of the plurality of wires. A power source is connected to the circuit board and to the base. A bracket is coupled to the bottom surface of the body and configured to receive the base. A patch is coupled to the bracket and has an adhesive. A needle is configured to be moveable by the actuator. The plurality of wires extend from the circuit board of the base, through the needle and out of the slot.

Abstract: A sphygmomanometer includes a frame that spatially demarcates a region in which a display screen is displayed. On the display screen, a scale indication for making a value of pressure readable is displayed along one direction. On the display screen, a mark that represents a pressure of a cuff by a position of the mark with respect to the scale indication is displayed. When the pressure changes, a display control unit performs control to slide the scale indication with respect to the frame along the one direction at a slide speed corresponding to a predetermined pressure change rate or a pressure change rate obtained by actual measurement in a pressurizing process or a depressurizing process of the cuff so that the mark falls within the frame.

Abstract: Systems and methods for wireless communication of analyte information are disclosed. Example embodiments include an analyte sensor system. The analyte sensor system may include an analyte sensor to gather information related to a level of an analyte in a host. The analyte sensor system may include circuitry to transmit and receive wireless signals using a first antenna. The analyte sensor may be coupled to the circuitry before the analyte sensor system is transitioned into an operational state. The analyte sensor system may include a second antenna to receive an input signal from a source external to the analyte sensor system and to transmit a modified signal. The circuitry may use the first antenna to receive the modified signal. The analyte sensor system may transition into the operational state in response to the modified signal received using the first antenna.

Abstract: Method and apparatus for providing an integrated transmitter unit and sensor insertion mechanism is provided.

Abstract: Biological chemicals, potentially found in blood are measured by collecting sweat and determining the concentration or meaning of the selected chemical in sweat. The sweat can be collected using a time based, interval collector and analyzed using an external device. It can also be collected on a one time basis, using a flexible, chemical capacitor, or on a continuous basis using a chemical, field effect transducer.

Abstract: The invention relates to a device for capture of cellular biomarkers circulating in an animal or human biological flow, characterised in that it is suitable for use in vivo and in that it comprises a means of filtration intended to retain the said cellular biomarkers, the said means of filtration comprising at least one through-aperture the dimensions of which are suitable for retaining the said cellular biomarkers and being integral with a support, the support taking the form of a hollow component.

Abstract: The present invention disclosed a device and method for assessing in real time the hypnotic and analgesic effect in a subject during wakefulness, sedation and general anaesthesia via drug interactions and physiological signals. In a preferred embodiment of the present invention, the analgesic and hypnotic effect of drug(s) infused in a subject could be accurately assessed in real time through the device and method disclosed in the present invention, comprising steps of receiving data from electroencephalography (EEG) device, receiving data from brain impedance tomography device, obtaining pharmacodynamic and pharmacokinetic parameters of drug(s) infused in the subject, defining initial indices of consciousness and nociception as a function of said EEG and brain impedance tomography data, and generating output of final indices of consciousness and nociception in real time from processing input of EEG, brain tomography and drug interaction data using established mathematical manipulation.

Abstract: A monitoring system for cardiac operations with cardiopulmonary bypass comprising: a processor operatively connected to a heart-lung machine; a pump flow detecting device connected to a pump of the heart-lung machine to continuously measure the pump flow value and send it to the processor; a hematocrit reading device inserted inside the arterial or venous line of the heart-lung machine to continuously measure the blood hematocrit value and to send it to the processor; a data input device to allow the operator to manually input data regarding the arterial oxygen saturation and the arterial oxygen tension; computing means integrated in the processor to compute the oxygen delivery value on the basis of the measured pump flow, the measured hematocrit value, the preset value of arterial oxygen saturation, and the preset value of arterial oxygen tension; and a display connected to the processor to display in real-time the computed oxygen delivery value.

Abstract: According to various aspects, a new concept of Steady-State Visually Evoked Potential (SSVEP) based Brain-Computer Interface (BCI) is described where brain-computer communication occurs by capturing SSVEP induced by consciously imperceptible visual stimuli integrated into, for example, a virtual scene. These consciously imperceptible visual stimuli are able to convey subliminal information to a computer. In various embodiments, computer based operations can be mapped to visual elements with associated flickering stimuli, and induced SSVEP can be detected when the user focused upon them. In various embodiments, these visual elements can be introduced into existing display without any perceivable change to content being displayed.

Abstract: A medical monitoring system for identifying an end-exhalation carbon dioxide value of enhanced clinical utility is described herein. The medical monitoring system can include a capnometer for generating an output corresponding to a time-series of exhaled carbon dioxide values from a patient during an exhalation and a processor programmed to analyze the exhalation. In some examples, the processor can also be programmed to identify a peak carbon dioxide value at an end of the exhalation, determine if the peak carbon dioxide value may have been higher if the exhalation had been prolonged, and provide an output responsive to said determination.

Abstract: Systems and methods for detecting noise episodes and processing analyte sensor data responsive thereto. In some embodiments, processing analyte sensor data includes filtering the sensor data to reduce or eliminate the effects of the noise episode on the signal.

Abstract: Embodiments include a system for determining patient cardiovascular information which includes at least one computer system configured to receive patient-specific data regarding a geometry of an anatomical structure of a patient; create a model representing at least a portion of the anatomical structure of the patient based on the patient-specific data; determine a first blood flow rate at at least one point of interest in the model by using relations of individual-specific anatomic data to functional estimates of blood flow characteristics generated from a plurality of individuals; modify the model; determine a second blood flow rate at a point in the modified model corresponding to the at least one point of interest by using the relations of individual-specific anatomic data to functional estimates of blood flow characteristics; and determine a fractional flow reserve value as a ratio of the second blood flow rate to the first blood flow rate.

Abstract: An apparatus for estimating an anaerobic threshold may include a heart rate detector configured to detect a heart rate from a signal sensed from a user, and an anaerobic threshold estimator configured to estimate an anaerobic threshold of the user based on a change in the detected heart rate.