Abstract: Methods and devices for reducing inflammation, reducing pro-inflammatory cytokines molecules and increasing anti-inflammatory signaling molecules in a mammal is provided. In at least one embodiment, a device comprising, a power supply; an amplifier; an antenna and a waveform generator is provided and the one or more signals have an aperiodic continuous waveform function or an aperiodic pulse train that reduce inflammation, reduce pro-inflammatory cytokines molecules and/or increases anti-inflammatory signaling molecules in a mammal.

Abstract: A method used for planning radiation treatment accessing information that includes calculated doses and calculated dose rates for sub-volumes in a treatment target, and also accessing information that includes values of a measure of the sub-volumes as a function of the calculated doses and the calculated dose rates. A graphical user interface includes a rendering that is based on the calculated doses, the calculated doses rates, and the values of the measure.

Abstract: A diagnostic hub located in a toilet receives a wireless signal from a mobile device of a user and determines that the user is proximate to the toilet based on the wireless signal. An identification of the user is determined based on the wireless signal. A geolocation of the diagnostic hub is determined. Sensor data generated by biometric sensors and environmental sensors is received. The diagnostic intakes a mixture of water and urine from the toilet into an intake chamber of the diagnostic hub through an inlet line or one or more openings in a housing of the diagnostic hub. A lab-on-a-chip of the diagnostic hub executes a biochemical assay on a fluid volume of the mixture using a reagent. Substance levels present in the urine are determined based on the biochemical assay. Results based on the substance levels are determined, indicating a diagnosis of one or more diseases or medical conditions.

Abstract: An intraosseous access system can include a needle that defines a lumen and a longitudinal axis about which the needle can be rotated during an insertion event. The needle can include a proximal end that remains at an exterior of a patient during use, a distal end that can be inserted through the skin of the patient into contact with a bone of the patient, and a distal tip at a distalmost point of the distal end of the needle that is positioned at the longitudinal axis of the needle. The system can further include an obturator sized to be received within the lumen of the needle that can inhibit material from entering the needle as the system is inserted into the bone.

Abstract: To provide a surgical clip capable of being held by, in particular, a robot arm or other device, thus promoting automation of a procedure. A surgical clip to pull an organ or other body tissue so as to provide an area necessary for an operation includes: a pair of upper and lower holders to hold the organ or other body tissue therebetween; a grip to open and close the holders; an urger to constantly urge the holders in a holding direction; and an engagement portion provided on the grip. The engagement portion comes into engagement with a hole defined in a functional part provided on a medical device that includes any one of a robot, forceps, and an applier. The functional part is configured to open and close so as to perform a holding, incising, or other operation.

Abstract: An adult toy is configured to communicate with a user device of a human user. Receipt of a plurality of input parameters is accumulated via the user device. In response to the accumulation satisfying a preset condition, the accumulation is stopped and a control signal is sent to actuate the adult toy to perform a series of predefined acts. The series of predefined acts are used to sexually stimulate the human user. The control signal includes one or more control sub-patterns, each of the one or more control sub-patterns being configured by each of the plurality of input parameters.

Abstract: The invention relates to a tissue receiving bag for use in surgery, especially laparoscopic surgery, wherein the bag comprises at least one tissue receiving opening for receiving tissue and/or an instrument opening, especially a morcellator opening, wherein the bag comprises at least one further opening into the bag, wherein a flexible tube extends from said further opening having a free end comprising an insertion opening for inserting an instrument into the bag, wherein the bag preferably is inflatable.

Abstract: A brachytherapy device including a base adapted for being at least partially introduced into a body of a subject and a plurality of radionuclide atoms of a first alpha-emitting isotope, coupled to the base in a manner that not more than 15% of the radionuclide atoms leave the base in 24 hours, in methods other than radioactive decay. When installed in a human subject, the brachytherapy device emits radionuclide atoms of the first alpha-emitting isotope at a rate of at least 0.1% of the number of radionuclide atoms of the first alpha-emitting isotope coupled to the base, per 24 hours.

Abstract: A method for treating a tumor, comprising identifying a tumor as a prostate cancer tumor and implanting in the tumor identified as a prostate cancer tumor, at least one diffusing alpha-emitter radiation therapy (DaRT) source with a suitable radon release rate and for a given duration, such that the source provides during the given duration a cumulated activity of released radon between 7 Mega becquerel (MBq) hour and 14.7 MBq hour, per centimeter length.

Abstract: This present invention is a novel method and wearable device for stimulating positive DNA gene expression and mitigating negative DNA gene expression in order to improve health and wellness. The invention's unique characteristics include the application of multiple modalities, their unique configuration for safe, low-power application, the wearable device's unique arrangement in a flat, flexible configuration for elastic contouring with comfort required for an extended period of wearing, and the ability to optimize and personalize the parameters and mixing among such modalities. The invention further combines biometric feedback data with Artificial Intelligence analytic capabilities, to facilitate the identification and characterization of DNA resonant frequencies, and associated “stimulus-response” modeling associated with such biological interactions.

Abstract: An interactive sex toy with sensory feedback is described herein. The sex toy may include a main body upper shell, a main body lower shell, and several trigger buttons, wherein the four trigger buttons are encased in the main body shell. Each of the four trigger buttons may include a mechanical spring and a conductive foam plastic. A motor maybe activated on a condition that at least one of the four trigger buttons is depressed. A pressure level may increase when an additional trigger button is depressed. A method for using an interactive sex toy with sensory feedback may include receiving physical pressure readings from an interactive sex toy with sensory feedback at a first device, converting the physical pressure readings to pressure parameter instructions, transmitting the pressure parameter instructions to a second device, and actuating a sex toy with the pressure parameter instructions.

Abstract: A system and a method for increasing permeability of a brain barrier selected from a blood-brain barrier or a blood-cerebrospinal fluid barrier by controlled application of pulsed electric fields.

Abstract: An implantable hearing unit is provided that includes an implantable microphone, a rechargeable power storage device and a speech signal processor. The hearing unit further includes a signal coupling device that is adapted for electrical interconnection to an implantable auditory stimulation device, which is operative to stimulate an auditory component of a patient. Such a stimulation device may include cochlear implants, brain stem stimulation systems, auditory nerve stimulation systems, and middle or inner ear transducer systems. The signal coupling device is operative to provide processed drive signals from the signal processor to the stimulation device as well provide power from the power storage device to operate the stimulation device. In one arrangement, the signal coupling device is a wireless coupling between first and second coils. In such an arrangement, the hearing unit may be utilized with an existing implanted stimulation device to make that device a fully implanted hearing system.

Abstract: The present disclosure provides for systems, methods, and devices for facilitating conception. According to the present disclosure, a conception facilitating device may comprise at least one frame and at least one base. In some embodiments, the at least one frame may be configured to at least partially surround the at least one base. In some aspects, the conception facilitating device may be configured to be insertable into a vaginal canal. The conception facilitating device may be comfortably inserted into a vaginal canal for a period of time, which may increase the possibility of conception.

Abstract: An implantable medical device, including a magnet and a body encompassing the magnet, wherein the implantable medical device includes structural components in the body configured to move away from one another upon initial rotation of the magnet relative to the body when the magnet is subjected to an externally generated magnetic field, thereby limiting rotation of the magnet beyond the initial rotation.

Abstract: A surgically implanted occluding assembly comprises an implant body having a longitudinally split generally “C”-shaped cross-section tube circumscribing an anatomical lumen. In one embodiment, the surgically implanted occluding assembly is a male continence device selectively occluding a urethra. In some embodiments an occluding magnet is rigidly affixed with the implant body, and an external selective occlusion control assembly is used to selectively activate the surgically implanted occluding assembly. The external assembly has a magnet, and body supporting the magnet. The external selective occlusion control assembly is configured to be selectively placed and retained adjacent to the surgically implanted occluding assembly.

Abstract: Methods, systems and devices for evaluating the integrity of a uterine cavity. A method comprises introducing transcervically a probe into a patient's uterine cavity, providing a flow of a fluid (e.g., CO2) through the probe into the uterine cavity and monitoring the rate of the flow to characterize the uterine cavity as perforated or non-perforated based on a change in the flow rate.

Abstract: Provided herein are devices, systems, and methods for monitoring lesion or treated area in a tissue during focal ablation or cell membrane disruption therapy.

Abstract: Examples relate to systems and methods for providing settings adjustments to auditory prostheses. One or more settings adjustments can be provided to an auditory device in response to a request for the adjustments or a notification that the recipient is experiencing poor quality. The technologies disclosed herein can dynamically adapt based upon information received from a set of auditory prostheses. The information received from the set of auditory prostheses can be used to update the settings adjustments.

Abstract: A tissue marking device enables the deployment of a hook to mark a location within a breast. The deployment is performed by inserting a needle in tissue until it arrives at a target location and pressing on the end of a rod that embeds the hook in the tissue. A thread is attached to the hook and is left exposed to facilitate locating the hook.