Abstract: Systems, devices, and methods are described for providing orthopedic implants that reduces the negative effects of stress shielding on surrounding bone structure. The orthopedic implants are comprised of two portions, a shell portion that forms an articulation interfaces and an intermediate portion that forms a bone interface. The shell portion is designed to reduce absorption of articulation forces and evenly distribute incident forces to the intermediate portion. The intermediate portion is designed to form a strong interface with native bone and transmit forces from the shell into the bone.

Abstract: A prosthetic heart valve includes a stent having a collapsed condition and an expanded condition. The stent has a proximal end, a distal end and a plurality of cells, each cell being formed by a plurality of struts. A valve assembly is secured to the stent and includes a cuff and a plurality of leaflets. The plurality of leaflets are attached to the cuff adjacent an underwire that extends about the perimeter of the cuff.

Abstract: Bone implant compositions and methods are provide that have a first surface and a second surface, the first surface and the second surface comprising a demineralized bone matrix and having a plurality of perforations configured to receive demineralized bone; and a third surface of the bone implant comprising cortical bone, the third surface disposed between the first surface and the second surface. The bone implant compositions and methods provided are osteoinductive and allow rapid bone fusion.

Abstract: A trochlear groove prosthesis includes a base plate and cap. The base plate and cap are shaped to correspond to the shape of the trochlear groove. A cut is made in the femur to remove the worn or damaged trochlear groove. The base plate is attached to the cut portion of the femur. The cap is mated with the base plate. The prosthesis and procedure provide a properly shaped prosthesis with a single planar cut of the femur.

Abstract: Knee prostheses that more faithfully replicate the structure and function of the human knee joint in order to provide, among other benefits: greater flexion of the knee in a more natural way by promoting or accommodating internal tibial rotation, replication of the natural screw home mechanism, and controlled articulation of the tibia and femur respective to each other in a natural way. Such prostheses may include an insert component disposed between a femoral component and a tibial component, the insert component featuring, among other things, a reversely contoured posterolateral bearing surface that helps impart internal rotation to the tibia as the knee flexes. Other surfaces can be shaped using iterative automated techniques that allow testing and iterative design taking into account a manageable set of major forces acting on the knee during normal functioning, together with information that is known about natural knee joint kinetics and kinematics.

Abstract: This invention relates to an implant having the capability of being adjusted to fit symmetrical and asymmetrical shaped voids formed in the bone or outside the bone of a patient. The implant can be individualized so as to accommodate various distortion in the void and can be disposed as a series of similar shaped implants that have different dimensions and/or characteristics to allow the surgeon to select an appropriate implant from said series.

Abstract: A prosthetic heart valve includes a collapsible and expandable stent having a proximal end, a distal end, an annulus section adjacent the proximal end and an aortic section adjacent the distal end, the stent including a plurality of struts. The heart valve further includes a collapsible and expandable valve assembly including a cuff and a plurality of leaflets, the cuff being coupled to selected ones of the plurality of struts and having microspheres disposed therein. The microspheres are capable of expanding upon contact with blood.

Abstract: A growth control device includes a bone plate having a stepped profile defined by a first level, a second level and an intermediate ramp connecting the first and second levels. The first level includes a first threaded hole for receiving a first bone fastener and the second level includes a second threaded hole for receiving a second bone fastener. The bone plate includes a proximal pair of side female notches, a distal pair of side female notches, a proximal guide hole and a distal guide hole.

Abstract: Spacer device for the two-phase treatment of infections of anatomic and reverse shoulder prostheses, including a humeral component equipped with a stem, a head component and means for connecting or articulating the humeral component with the head component.

Abstract: An accommodating intraocular lens (IOL) comprises an anterior lens, a posterior surface and an articulating member joining the anterior lens and the posterior surface to define an enclosed cavity. The articulating member comprises anterior and posterior arms coupling the anterior lens and the posterior surface, respectively. The articulating member further comprising a peripheral portion. A posterior flex region is disposed about the posterior arm and at a distance from the peripheral portion. The posterior flex region permits the flexible posterior surface to articulate relative to the posterior arm, to decrease the radius of curvature of the posterior surface as the peripheral portions on opposing sides of the IOL move toward one another in a first state and to increase the radius of curvature of the posterior surface as the peripheral portions on opposite sides of the IOL move away from one another in a second state.

Abstract: A retractor blade comprising a blade body having first and second ends, the first end including means to allow connection of the blade body to a support member, the second end including a first part disposed in a first plane and a second part disposed in a second plane, wherein the first and second parts are orthogonal and at least one of said first and second parts terminates in an end at least part of which includes a contour which generally conforms to a contour of a spinal vertebrae.

Abstract: A prosthesis and a method for directing flow through a passageway formed between a first bodily lumen and a second bodily lumen are provided. The prosthesis includes a body having a proximal portion, a distal portion and a lumen extending therethrough. The prosthesis also includes a sleeve operably connected to the body at a connected portion. The sleeve has a proximal portion, a distal portion, and a sleeve lumen extending therethrough. At least a portion of the body is positioned within at least a portion of the sleeve lumen and the distal portion of the sleeve is free from connection to the distal portion of the body and extendable away from the body to contact a wall of the first bodily lumen. The sleeve is configured to allow fluid flow through the sleeve lumen from the first bodily lumen to the second bodily lumen.

Abstract: An orthopedic surgical instrument includes a patella trial and drill guide that may be used to both perform a surgical trial of the patellofemoral joint and guide the surgeon in drilling a number of anchor holes in the patella of the patient.

Abstract: An adjustable construct for fixation of a tendon or ligament graft in a tunnel. The construct comprises a flexible, adjustable loop connected to tissue (for example, graft, ligament or tendon). The adjustable loop may be integrated with an additional tissue supporting device (for example, a wedge or a plug). The tissue is secured within a bone socket/tunnel by adjusting the length of the flexible adjustable loop.

Abstract: An implantable ophthalmic device with flexible, fluid-filled membranes provide dynamically variable optical power to restore lost accommodation in individuals suffering from presbyopia or aphakia without moving parts or reducing the amount of transmitted light. Actuating the device causes the fluid-filled membrane to change curvature, which produces a corresponding change in optical power. For instance, squeezing the edge of the membrane causes the center of the membrane to bulge by an amount proportional to the squeezing force. Alternatively, heating or applying a voltage to the membrane may cause the liquid in the membrane to undergo a phase transition accompanied by a corresponding change in volume that causes the membrane to inflate so as to change the optical power of the device.

Abstract: Dimensionally adjustable spinal prostheses are adjustable in an axial or superior to inferior dimension such that spinal prostheses may assume variations in height. The height adjustable spinal prostheses are characterized by first and second portions that are configured for adjustable coupling with one another. Spatial adjustment between the first and second portions is provided by an adjustment assembly. The adjustment mechanism preferably, but not necessarily, provides infinite adjustment over a minimum prosthesis height to a maximum prosthesis height. In one form, first and second ends of the height adjustable spinal prostheses are configured to receive an endplate. The endplates aid in attachment and/or anchoring of the spinal prosthesis within the spine. The endplates may be fashioned in various configurations such as circular or anatomical. In one form, the adjustment assembly utilizes rotational motion for varying the axial position of one prosthetic portion relative to the other prosthetic portion.

Abstract: An orthopaedic knee prosthesis includes a femoral component which exhibits enhanced articular features, minimizes removal of healthy bone stock from the distal femur, and minimizes the impact of the prosthesis on adjacent soft tissues of the knee.

Abstract: An intraocular lens includes an optic, which includes a first lens having a first optical axis for alignment with an optical axis of the human eye having a macula; and a second lens having a second optical axis. The second optical axis and the first optical axis enclose an angle between 0.5 and 10 degrees. The first and second lens are arranged next to one another in a direction transverse to the first optical axis to provide no overlap in a direction along the first optical axis such that the first lens and the second lens each, independent from one another, image onto the macula of the eye. The angle and a direction of the second optical axis are chosen such that the second lens images onto a functional part of the macula of the human eye, which functional part is not compromised by a defect, such as a scotoma.

Abstract: An intervertebral implant system installable between a pair of vertebrae. The implant includes a spacer that fits between the pair of vertebrae with a screw aperture for passage of a first screw and angled to orient the first screw into a first vertebrae at an angle relative to the rear sidewall of the spacer so that the first screw will enter an endplate of the first vertebrae. A plate is installable onto the rear sidewall of the polymeric spacer. The plate includes an angled screw aperture that is aligned with the screw aperture of the spacer when the plate is installed on the spacer. An elevated screw support extends upwardly or downwardly from the plate so as to extend opposite the direction of the angled screw aperture. The elevated screw support locates a second screw to enter a second vertebrae through an anterior surface of the second vertebrae.

Abstract: There is provided a tibial component comprising: a tibial tray with an inferior side; and a support member connected to the inferior side of the tibial tray, the support member having a stem portion, the support member further comprising at least one opening. In one embodiment, the at least one opening is constructed and arranged to receive a sawblade or an osteotome. In another embodiment, the at least one opening is comprised of solid material but is radio-lucent. In yet another embodiment, the at least one opening is comprised of solid material and is frangible.