Abstract: A non-aqueous medicinal aerosol formulation comprising rosiglitazone maleate, a fluid carrier, and an amino acid stabilizer. The aerosol formulation may also include drug combination formulations comprising rosiglitazone maleate and a second anti-diabetic medicament.
Type:
Grant
Filed:
October 31, 2000
Date of Patent:
October 22, 2002
Assignee:
Aeropharm Technology, Inc.
Inventors:
Anthony J. Cutie, Akwete L. Adjei, Frederick A. Sexton
Abstract: The aerosol hair spray composition contains a hair-setting polymer in a solvent/propellant system containing a C1 to C4 alcohol, water, a cosolvent selected from among acetone and methyl acetate or a mixture thereof, and aerosol propellants, particularly a combination of dimethyl ether and a fluorocarbon. The composition according to the invention makes it possible to produce low-cost, water-containing aerosol hair sprays with a reduced VOC content and at the same time to optimize their use properties.
Abstract: A non-aqueous medicament aerosol formulation comprising troglitazone, or a derivative thereof, a fluid carrier, and an amino acid stabilizer. The aerosol formulation may also include drug combination formulations comprising troglitazone and a second anti-diabetic medicament.
Abstract: A cosmetic consists of a cosmetic raw material in the form of an emulsion of silicone or organic oil containing crosslinked particles mixed with other cosmetic raw materials. Its touch on fingers and skin is good, spreading and feel during use are good, and it can also prevent unruly hair, stray hair, and tangling of hair, so hair can easily be arranged. It imparts a fresh, dry feeling without any stickiness. The cosmetic raw material consists of the silicone or organic oil emulsion containing crosslinked particles with a mean particle diameter of 0.05 to 100 &mgr;m. Crosslinking is obtained by an hydrosilylation of liquid crosslinkable compositions consisting of (A) organic compounds with at least two aliphatic unsaturated bonds per molecule, (B) silicon containing organic compounds with at least two hydrogen atoms bonded to silicon atoms in each molecule, and (C) hydrosilylation reaction catalysts.
Abstract: The present invention relates to a method for transferring one or more active ingredients between different phase carriers, which includes: (a) providing a solid, semi-solid, or nonaqueous liquid drug which contains at least one active ingredient; (b) admixing said drug with water or water solution to form an admixture; and (c) nebulizing said admixture to form liquid fine drops containing said active ingredient. This method enables the active ingredient stored in a solid phase carrier to transfer into an aqueous phase carrier, or enables the active ingredient stored in a non-aqueous liquid carrier to transfer into an aqueous phase carrier. The aqueous phase carrier contains the active ingredient can then be nebulized with a nebulizer by means of ultrasonic vibration. The present invention provides a new method for controlling administration by transferring the active ingredient between different phase carriers.
Abstract: A cosmetic composition is provided which includes at least about 2% solid asymmetric particles, a retinoid solubilized in a fluid oil and wherein the fluid oil to solid particles are present in a weight ratio such that the composition exhibits a normal force value of less than −100 milli-Newton containing a retinoid. The composition diminishes the appearance and feel of oily skin and is capable of delivering benefits associated with retinoids.
Type:
Grant
Filed:
July 26, 2001
Date of Patent:
September 17, 2002
Assignee:
Unilever Home & Personal Care, USA, division of Conopco,
Inc.
Abstract: Cosmetic skin care compositions containing a high performing retinyl ester which is an ester of retinol with C18, unsaturated, non-essential, cis-6 and/or cis-12 fatty acid. The ester is preferably selected from the group consisting of gamma-retinyl linolenate, retinyl petroselinate, and retinyl cis-12-octadecenoate.
Type:
Grant
Filed:
April 18, 2001
Date of Patent:
August 20, 2002
Assignee:
Unilever Home & Personal Care USA, division of Conopco,
Inc.
Inventors:
Stewart Paton Granger, Susanne Teklits Iobst, Marieann Barratt, Richard John Kosturko, Victor DeFlorio, Ian Richard Scott
Abstract: Described is a process for preparing beclomethsaone dipropionate Freon® clathrate comprising the use of an agent which selectively binds methanol to selectively remove methanol from a mixture of methanol and Freon® 11 containing beclomethasone dipropionate.
Abstract: The invention relates to a device and method for the treatment of Alzheimer's dementia with desoxypeganine and/or a pharmaceutically acceptable acid addition salt of desoxypeganine.
Type:
Grant
Filed:
August 16, 2001
Date of Patent:
August 20, 2002
Assignee:
LTS Lohman-Therapie Systeme AG
Inventors:
Bodo Asmussen, Thomas Hille, Hans-Rainer Hoffmann, Klaus Opitz
Abstract: Oral composition comprises a wintergreen flavor imparting ingredient and having an alkaline pH, wherein the wintergreen flavor imparting ingredient is 2′-hydroxypropiophenone.
Type:
Grant
Filed:
March 13, 2001
Date of Patent:
August 20, 2002
Assignee:
Unilever Home & Personal Care USA, division of Conopco,
Inc.
Abstract: A substantially alcohol-free composition for treatment of acne contains about 0.05 to 26% by weight salicylic acid and about 0.05 to 28% by weight of a solubilizing agent for the salicylic acid, which is sodium tetraborate, sodium carbonate or sodium bicarbonate, dissolved in a cosmetically acceptable aqueous medium.
Abstract: Cosmetic compositions comprising, in a cosmetically acceptable medium:
(1) at least one film-forming polymer (A), wherein a film obtained by drying a mixture of said polymer (A) with ethanol or water, at room temperature and at a relative humidity of 50%, has a mechanical profile defined by at least:
(i) a degree of elongation at break (&egr;r) of greater than or equal to 300%;
(ii) a recovery at 300 seconds (R300) of greater than or equal to 45%; and
(iii) if the recovery at 300 seconds (R300) is from 45% to 60%, then the elongation at break is less than or equal to 1300%; and
(2) at least one crosslinked thickening polymer (B) comprising at least one (meth)acrylic acid monomeric, wherein said at least one polymer (B) is present in the composition in an amount ranging from at least 0.6% by weight, relative to the total weight of the composition.
Abstract: Cosmetic compositions comprising at least one film-forming polymer, in a cosmetically acceptable medium, wherein said at least one film-forming polymer has, at the polymer concentration of the composition, a mechanical profile, measured in an aqueous-alcoholic medium comprising 20% by volume of ethanol, defined by at least:
(i) an attachment angle &agr; of greater than 47°, and
(ii) if &agr; is greater than or equal to 90°, a maximum detachment force Fmax<5 newtons.
Abstract: A composition for topical aerosol application contains, by weight, a) about 20 to 90% of an active mixture in the form of a solution, gel or lotion with salicylic acid or benzoyl peroxide as active ingredient, and optionally, a polymeric thickening agent for a gel or lotion, and b) about 10 to 80% of a propellant system which includes dimethyl ether. The composition has a temperature in the range of 3 to 25° C. when dispensed.
Abstract: A composition having analgesic, antiseptic and skin healing promoting activity, suitable for the treatment of burns, sunburns, scalds, irritation, sores and abrasions which includes, as active ingredients, chlorophyll, cod liver oil, and camphor, preferably together with a natural antiseptic agent chosen from niaouli oil, thyme oil, and mixtures thereof, in a pharmaceutically acceptable vehicle for topical application.
Abstract: Disclosed is a composition including a lower alcohol and water in a weight ratio of about 35:65 to 100:0, between at least 0.5% and 8.0% by weight thickener system comprised of at least two emulsifiers, each emulsifier present in at least 0.05% by weight wherein the composition free of auxiliary thickeners has a viscosity of at least 4,000 centipoise at 23 degrees C. and wherein each emulsifier is comprised of at least one hydrophobic group and at least one hydrophilic group. The composition is useful as a presurgical scrub replacement, a lotion or other hand preparation.
Type:
Grant
Filed:
May 27, 1999
Date of Patent:
March 5, 2002
Assignee:
3M Innovative Properties Company
Inventors:
Matthew T. Scholz, Robert A. Asmus, Jill R. Charpentier
Abstract: A cosmetic or dermatological composition, comprising:
in combination, at least one extract of mulberry or an active substance isolated from the extract, at least one extract of skullcap or an active substance isolated from the extract and at least one salicylic acid derivative or salt thereof.
Abstract: A transfer-resistant make-up or care composition, comprising:
a fatty phase, and
a volatile solvent comprising a linear decamethyltetrasiloxane and at least one additional solvent which has an evaporation speed that is greater than the evaporation speed of the linear decamethyltetrasiloxane.
Abstract: An analgesic/anti-inflammatory pharmaceutical dosage form which comprises an effective amount of an active ingredient selected from the group consisting of racemic 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid, optically active forms thereof and pharmaceutically acceptable salts thereof, in combination with a pharmaceutically acceptable excipient or diluent, said dosage form being an intranasally administrable dosage form.
Type:
Grant
Filed:
February 1, 1995
Date of Patent:
December 25, 2001
Assignee:
Recordati, S.A. Chemical and Pharmaceutical Company
Inventors:
Giancarlo Santus, Giuseppe Bottoni, Ettore Bilato
Abstract: A structured cosmetic material which includes water, a fat component, an o/w emulsifier, a w/o emulsifier, a polysaccharide such as &kgr;-carragheen forming a three-dimensional network, and optionally conventional components.
Type:
Grant
Filed:
October 31, 2000
Date of Patent:
August 14, 2001
Assignee:
Schwan-Stabilo Cosmetics GmbH & Co.
Inventors:
Werner Bruechert, Willy Weiss, Michael Healy