Patents Examined by Colin T Sakamoto
  • Patent number: 11123033
    Abstract: Disclosed is a molecular imaging method for evaluating liver regeneration ability after ALPPS. The method includes steps of: 1) preparing a VX2 rabbit liver cancer model; 2) performing ALPPS for the VX2 rabbit liver cancer model; 3) synthesizing 18F-Fluoromethylcholine (18F-Methylcholine, 18F-FCH); 4) PET/CT imaging and data processing for 18F-FCH. The disclosure is the first to propose the use of 18F-FCH PET/CT to monitor the proliferative capacity of residual liver, and further indirectly reflect the increased ability of cell membrane synthesis on the basis that 18F-FCH has higher choline metabolism in residual liver tissue, so that the liver regeneration ability after ALPPS is evaluated by the molecular imaging method, thereby providing important new ideas for the clinical selection of ALPPS to choose the best time for second-stage surgery.
    Type: Grant
    Filed: September 30, 2020
    Date of Patent: September 21, 2021
    Assignee: Harbin Medical University
    Inventors: Xilin Sun, Zhen Quan, Ruifeng Wang, Kai Wang, Lili Yang, Zunyu Xiao, Yang Liu, Zhaoguo Han, Xiang Liu, Mingxing Ke
  • Patent number: 11123034
    Abstract: An imaging system includes radiation source that emits radiation that traverses an examination region and a portion of a subject therein and a detector array that detects radiation that traverses the examination region and the portion of the subject therein and generates a signal indicative thereof. A volume scan parameter recommender recommends at least one spectral scan parameter value for a volume scan of the portion of the subject based on a spectral decomposition of first and second 2D projections acquired by the radiation source and detector array. The first and second 2D projections have different spectral characteristics. A console employs the recommended at least one spectral scan parameter value to perform the volume scan of the portion of the subject.
    Type: Grant
    Filed: October 25, 2019
    Date of Patent: September 21, 2021
    Inventors: Dirk Schaefer, Axel Thran, Thomas Koehler
  • Patent number: 11103135
    Abstract: Surgical devices and methods for utilizing optical coherence tomography (OCT) to monitor and control tissue sealing are disclosed. The surgical device includes an end effector assembly that includes first and second jaw members that are movable between a first, spaced-apart position and a second proximate position. An OCT system, at least a portion of which is incorporated into the end effector assembly, is configured to sense properties of the tissue, e.g., the structural density of the tissue, disposed between the first and second jaw members. A tissue-sealing energy source may be disposed within at least one of the jaw members and may provide tissue-sealing energy to tissue disposed between the jaw members. A controller, which is coupled to the OCT system and the tissue-sealing energy source, controls the tissue-sealing energy generated by the tissue-sealing energy source based on the properties of the tissue sensed by the OCT system.
    Type: Grant
    Filed: February 14, 2019
    Date of Patent: August 31, 2021
    Assignee: Covidien LP
    Inventor: William H. Nau, Jr.
  • Patent number: 11064973
    Abstract: An ultrasound probe according to an embodiment includes: transducer elements, phase reversal processing circuitry, and delay processing circuitry. The transducer elements, each of which is configured to generate a first echo signal by receiving a reflected wave of a first ultrasound wave and to generate a second echo signal by receiving a reflected wave of a second ultrasound wave corresponding to an ultrasound wave obtained by reversing the phase of the first ultrasound wave. The phase reversal processing circuitry is configured to reverse the phase of the second echo signal. The delay processing circuitry is configured to delay the first echo signal and the phase-reversed second echo signal.
    Type: Grant
    Filed: July 5, 2018
    Date of Patent: July 20, 2021
    Inventor: Masaaki Ishitsuka
  • Patent number: 11051761
    Abstract: Intravascular imaging catheters are provided that include a distal sheath portion having a lumen that is configured to optionally receive a guidewire or an imaging assembly. The distal sheath portion may be configured to have dimensions such that when a guidewire is inserted through the lumen and extends through a distal exit port, the distal sheath portion may be employed as a microcatheter. External tissue may be imaged at a location at or near the distal end of the catheter, enabling, for example, the controlled imaging of a total occlusion, and the positioning of the distal end (and guidewire) within a true lumen associated with a total occlusion. A structural stop may be provided at or near the distal end of the distal sheath portion to prohibit extension of the imaging assembly out of the distal exit port, while permitting the extension of the guidewire through the distal exit port.
    Type: Grant
    Filed: June 15, 2016
    Date of Patent: July 6, 2021
    Inventors: Brian Courtney, Isaac Jourard, Deniz Jafari
  • Patent number: 11026656
    Abstract: The invention relates to an ultrasound data visualization apparatus for visualizing ultrasound data showing an object during an interventional procedure. A reference image (65) and a current image (68) of the object are simultaneously displayed, wherein the current image corresponds to a current time interval and the reference image corresponds to a reference time interval and wherein the current time interval and the reference time interval correspond to different phases of the interventional procedure. The current image can be shown therefore with, for instance, a relatively high temporal resolution for allowing a user to observe detailed object changes, which may be caused by the interventional procedure, while an overview over different phases of the interventional procedure can still be provided, because also the reference image is displayed and can be used by a user for comparing the current image with the reference image.
    Type: Grant
    Filed: September 12, 2013
    Date of Patent: June 8, 2021
    Inventors: Harm Jan Willem Belt, Godefridus Antonius Harks, Steven Antonie Willem Fokkenrood, Monica Tavanti, Alexander Franciscus Kolen
  • Patent number: 11013414
    Abstract: A multispectral synchronized imaging system is provided. A multispectral light source of the system includes: blue, green and red LEDs, and one or more non-visible light sources, each being independently addressable and configured to emit, in a sequence: at least visible white light, and non-visible light in one or more given non-visible frequency ranges. The system further includes a camera and an optical filter arranged to filter light received at the camera, by: transmitting visible light from the LEDs; filter out non-visible light from the non-visible light sources; and otherwise transmit excited light emitted by a tissue sample excited by non-visible light. Images acquired by the camera are output to a display device. A control unit synchronizes acquisition of respective images at the camera for each of blue light, green light, visible white light, and excited light received at the camera, as reflected by the tissue sample.
    Type: Grant
    Filed: May 10, 2016
    Date of Patent: May 25, 2021
    Inventors: Ze Shan Yao, Piotr Kuchnio, Michael Frank Gunter Wood, Tammy Kee-Wai Lee, Yanhui Bai, Michael Peter Bulk, Christopher Thomas Jamieson
  • Patent number: 10987069
    Abstract: An N-M tomography system comprising: a carrier for the subject of an examination procedure; a plurality of detector heads; a carrier for the detector heads; and a detector positioning arrangement operable to position the detector heads during performance of a scan without interference or collision between adjacent detector heads to establish a variable bore size and configuration for the examination. Additionally, collimated detectors providing variable spatial resolution for SPECT imaging and which can also be used for PET imaging, whereby one set of detectors can be selectably used for either modality, or for both simultaneously.
    Type: Grant
    Filed: May 8, 2013
    Date of Patent: April 27, 2021
    Assignee: Spectrum Dynamics Medical Limited
    Inventors: Nathaniel Roth, Yoel Zilberstein, Shlomo Ben-Haim, Benny Rousso
  • Patent number: 10987187
    Abstract: The present invention generally relates to a medical device including a movable instrument (MI) which is activated only when its movement is within an optimal range of acceleration. More particularly the invention relates to a fetal heart rate monitor (FHRM) having a movable Doppler transducer which transceives ultrasound energy only when found within a certain optimal range of acceleration.
    Type: Grant
    Filed: November 10, 2014
    Date of Patent: April 27, 2021
    Assignee: Hera Med Ltd.
    Inventors: David Groberman, Tal Slonim, Shimon Hayun, Joel Rotem, Michael Nenner
  • Patent number: 10987492
    Abstract: A guidewire providing imaging and light for photoactivation of therapeutic agents. Using optical fibers with Bragg gratings, electromagnetic waves are coupled to photoacoustic materials thereby providing acoustic energy for imaging tissues. The reflected acoustic waves can be sensed with photoreflective materials coupled to different optical fibers. Additional optical fibers allow photoactivated therapeutics to be activated in proximity to the imaged tissues. The photoactivated therapeutics may be administered intravenously or with a drug-delivery catheter.
    Type: Grant
    Filed: December 18, 2013
    Date of Patent: April 27, 2021
    Inventor: Paul Hoseit
  • Patent number: 10973493
    Abstract: Disclosed is an ultrasound diagnostic apparatus. The ultrasound diagnostic apparatus includes a holder implemented to hold a probe; an object sensor for detecting physical changes around the holder; an electromagnetic wave sensor for detecting electromagnetic waves around the holder; and a controller for determining a port name for a probe held in the holder, based on sensing values from the object sensor and electromagnetic wave sensor.
    Type: Grant
    Filed: April 8, 2016
    Date of Patent: April 13, 2021
    Inventor: Chil Su Kim
  • Patent number: 10966685
    Abstract: A method of providing an ultrasound elastography image that includes inducing a shear wave by transmitting a first ultrasound signal pushing an object to the object, transmitting a second ultrasound signal tracing the shear wave to the object to receive a response signal to the second ultrasound signal from the object; acquiring an elastography image of the object, based on the response signal, and providing the elastography image of the object and transmission position information of the first ultrasound signal.
    Type: Grant
    Filed: September 29, 2014
    Date of Patent: April 6, 2021
    Inventors: Ji-young Park, Jun-ho Park, Ki-wan Choi, Hyoung-ki Lee
  • Patent number: 10966688
    Abstract: A method for fusion of live ultrasound imagery with computed tomography (CT) scan images or magnetic resonance images, the method comprising steps of acquiring a series of CT scan images or magnetic resonance images, acquiring a series of ultrasound images, applying a manual registration process on a computing device to register each of the CT scan images or magnetic resonance images with corresponding ultrasound images, and displaying on a display associated with the computing device the live ultrasound imagery and corresponding CT scan images or magnetic resonance images.
    Type: Grant
    Filed: March 16, 2015
    Date of Patent: April 6, 2021
    Assignee: Rational Surgical Solutions, LLC
    Inventor: Jonathan Fialkov
  • Patent number: 10908238
    Abstract: A magnetic resonance (MR) coil unit, comprising: —an MR coil body which houses at least one MR coil, the MR coil body having a front surface for facing a patient, a reverse surface opposite to the front surface, and at least one opening through the MR coil body which connects the front and reverse surfaces; —at least one MR marker located at least partly in said at least one opening in the MR coil body; and—at least one optical marker located above the reverse surface of the MR coil body.
    Type: Grant
    Filed: October 25, 2013
    Date of Patent: February 2, 2021
    Inventors: Patrick Gross, Tilman Niederführ, Brian Vasey, Nadja Heindl, Dimitrios Sapnaras
  • Patent number: 10856840
    Abstract: A universal ultrasound device having an ultrasound includes a semiconductor die; a plurality of ultrasonic transducers integrated on the semiconductor die, the plurality of ultrasonic transducers configured to operate a first mode associated with a first frequency range and a second mode associated with a second frequency range, wherein the first frequency range is at least partially non-overlapping with the second frequency range; and control circuitry configured to: control the plurality of ultrasonic transducers to generate and/or detect ultrasound signals having frequencies in the first frequency range, in response to receiving an indication to operate the ultrasound probe in the first mode; and control the plurality of ultrasonic transducers to generate and/or detect ultrasound signals having frequencies in the second frequency range, in response to receiving an indication to operate the ultrasound probe in the second mode.
    Type: Grant
    Filed: January 25, 2017
    Date of Patent: December 8, 2020
    Assignee: Butterfly Network, Inc.
    Inventors: Jonathan M. Rothberg, Susan A. Alie, Nevada J. Sanchez, Tyler S. Ralston, Christopher Thomas McNulty, Jaime Scott Zahorian, Paul Francis Cristman, Matthew de Jonge, Keith G. Fife
  • Patent number: 10856749
    Abstract: A monitoring device includes a biasing element having opposite first and second end portions, an earbud attached to the biasing element first end portion, and a sensing element attached to the biasing element second end portion. The earbud has a first mass, and the sensing element has a second mass that is less than the first mass. The biasing element is configured to urge the sensing element into contact with a portion of the ear when the earbud is inserted into the ear. The biasing element decouples motion of the earbud from the sensing element. The sensing element includes at least one energy emitter configured to direct energy at a target region of the ear and at least one detector configured to detect an energy response signal from the target region or a region adjacent the target region.
    Type: Grant
    Filed: January 24, 2014
    Date of Patent: December 8, 2020
    Assignee: Valencell, Inc.
    Inventors: Steven Matthew Just, Jesse Berkley Tucker, Robert Splinter, Steven Francis LeBoeuf
  • Patent number: 10849546
    Abstract: Discussed herein is a parametric model for DTI MD histogram fitting, named the Generalized Voss-Dyke function, which is highly successful in segregating NPH cases from potential confounders without reliance on operator dependent region-of-interest analyses or inter-subject registration. The Generalized Voss-Dyke function is useful for managing the imaging of any tissue interfaces.
    Type: Grant
    Filed: November 11, 2014
    Date of Patent: December 1, 2020
    Inventors: Milos Ivkovic, Norman Relkin, Henning U. Voss, Jonathan P. Dyke
  • Patent number: 10835202
    Abstract: A system and method for determining tissue changes. Shear waves are transmitted across the tissue in response to an ultrasonic signal input exterior to the tissue surface. Adaptive beam forming signal processing is applied to signal returns and arrivals to remove distortions by targeting velocity contrasts. Shear-wave dispersion, such as due to viscosity and mass changes in the tissue, are then estimated and compared to reference data to determine tissue health.
    Type: Grant
    Filed: November 11, 2014
    Date of Patent: November 17, 2020
    Assignee: Massachusetts Institute of Technology
    Inventor: Robert W. Haupt
  • Patent number: 10806430
    Abstract: A probe transmission device comprises a drive shaft which is provided with a radial hole and an axial hole, wherein the radial hole is in communication with the axial hole. A rope extends into the axial hole via the radial hole. A fixing component is arranged within the axial hole and fixes the rope within the radial hole. The probe transmission device is provided with the radial hole and the axial hole on the drive shaft. The rope extends into the radial hole and is fixed via the fixing component which is arranged with the axial hole. The structure of the present probe transmission is simple. The surface of the drive shaft does not require a component for fixing the rope, and the surface of the drive shaft is smooth. Interference produced by the rope and components on the surface of the drive shaft is avoided.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: October 20, 2020
    Inventors: Ming Tang, Zhenyu Chen, Leyun Bai
  • Patent number: 10799212
    Abstract: Provided are a portable ultrasound apparatus, a portable ultrasound system, and an ultrasound diagnosis method performed by using the portable ultrasound apparatus. The portable ultrasound apparatus includes at least two probes having different specifications; a first display unit for displaying an ultrasound image; and a second display unit for displaying a control screen.
    Type: Grant
    Filed: October 22, 2013
    Date of Patent: October 13, 2020
    Assignee: Samsung Medison Co., Ltd.
    Inventors: Gil-ju Jin, Mi-jeoung Ahn, Hyoung-jin Kim