Abstract: Tetrahydrofurans, tetrahydrothiophenes, pyrrolidines and cyclopentanes are disclosed that reduce the chemotaxis and respiratory burst leading to the formation of damaging oxygen radicals of polymorphonuclear leukocytes during an inflammatory or immune response. It has been determined that 5-lipoxygenase activity, oral availability, and stability in vivo (for example, glucuronidation rate) can vary significantly among the optical isomers of the disclosed compounds.

Abstract: The invention provides a method for the treatment of endotoxic shock comprising administering to a human or other mammal in need of such a treatment an effective amount of choline for reducing endotoxin-induced injury and mortality and a nutritional composition comprising choline, whereby the composition provides a daily dosage of at least 1.5 g choline, the upper limit being 20 g of choline per day.

Abstract: There are disclosed cosmetics which comprise N-acylamino acids containing acyl groups having specifically numbered carbon atoms, or derivatives thereof and which are well suited for hair growth, skin care and the like; N-acylamino acid compositions which are favorably usable for detergents, dispersants, emulsifying agents, antimicrobial drugs, antiseptics, ultraviolet absorbers and the like. The invention provides cosmetics which comprise N-acylamino acids containing acyl groups having odd-numbered carbon atoms, salts thereof or esters thereof; N-acylamino acid compositions; and further N-acylamino acids containing acyl groups having carbon atoms in an odd number in the range of 13 to 17 along with salts and esters thereof.

Abstract: A topical composition for healing treatment of burns and wounds and scarring therefrom has as the active ingredient cereal-derived (1-3) (1-4) .beta.-D-glucan at about 0.5-15 w/w percent. The composition may be formulated in various forms with creams and gels being preferred for application to the skin.

Abstract: A patch for topical application of an anti-acne formulation has in various embodiments a backing film, a release layer and at least one adhesive polymeric matrix layer located between the backing film and the release layer. The anti-acne formulation is uniformly distributed throughout one or more polymeric matrix layers and has an anti-acne effective amount of at least two agents selected from the group consisting of an anti-microbial, an antiseptic, an anti-irritant, a keratolytic agent, a hormone, a hormone agonist and a hormone antagonist.

Abstract: The invention provides high purity branched alkylsilsesquioxane containing fluids of the general formula Me.sub.3 SiO--(Me.sub.3 SiORSiO).sub.x --SiMe.sub.3, wherein Me is methyl, R is a monovalent hydrocarbon substituent, and x is 1 to 6, and an essentially zero waste process for their synthesis in quantitative yield; and especially n-octylsilsesquioxane containing fluids which are structural analogs of phenylsilsesquioxane containing fluids of the general formula Me.sub.3 SiO--(Me.sub.3 SiOPhSiO).sub.x --SiMe.sub.3, wherein Me is methyl, Ph is phenyl, x is 1 to 6, and have substantially identical sensory properties to their phenylsilsesquioxane counterparts.

Abstract: The present invention provides consumable, gummy delivery systems and methods of making the same. The gummy delivery systems include an active ingredient admixed with a glycerylated gelatin matrix prepared by heating an aqueous solution of gelatin and glycerin to a temperature and for a time sufficient to remove some of the moisture content of the initial aqueous solution. The active ingredient can be delivered from a shearform matrix carrier.

Abstract: The natural poison skin treatment method of the present invention includes applying to skin a composition including an effective amount of natural poison skin treatment medication selected from the group consisting of benzoyl peroxide and salicylic acid, an effective amount of a vasoconstrictor and an inert carrier. The natural poison skin treatment medication is therapeutic to natural poison skin conditions by acting as an antibacterial agent. The vasoconstrictor removes the redness normally associated with natural poison skin conditions as well as additional redness which may be caused by the benzoyl peroxide itself. The carrier is simply an inert flowing carrier to permit the application of the active ingredients to the skin. In preferred embodiments about 1 to 15% of the natural poison skin treatment medication based on the total weight of the composition is included.

Abstract: The acne treatment composition of the present invention includes an effective amount of acne treatment medication selected from the group consisting of benzoyl peroxide and salicylic acid, and effective amount of a vasoconstrictor and an inert carrier. The acne treatment medication is therapeutic to acne conditions by acting as an antibacterial agent. The vasoconstrictor removes the redness normally associated with acne conditions as well as additional redness which may be caused by the benzoyl peroxide itself. The carrier is simply an inert flowing carrier to permit application of the active ingredients to the skin. In preferred embodiments about 1 to 15% of the acne treatment medication based on the total weight of the composition is included. The preferred acne treatment medication is benzoyl peroxide and the preferred vasoconstrictor is tetrahydrozoline hydrochloride or a combination of tetrahydrozoline hydrochloride and zinc sulfate.

Abstract: Stable reverse water-in-fluorocarbon emulsions and water-in-fluorocarbon-in-water multiple emulsions comprising the reverse fluorocarbon emulsions. The reverse emulsions comprise a continuous phase which is a highly fluorinated or perfluorinated compound, a discontinuous aqueous phase and a fluorinated surfactant or mixture of surfactants. The multiple emulsions comprise an aqueous continuous phase and a discontinuous phase comprising globules formed of aqueous droplets dispersed into a highly fluorinated or perfluorinated compound. The emulsions can contain pharmacologically active agents, and are particularly suitable for pulmonary drug delivery.

Abstract: Provided are enteric coating compositions which utilize a low viscosity cellulose acetate phthalate polymer as a film former. The cellulose acetate phthalates have an inherent viscosity of about 0.2 to 0.6 dL/g and phthalyl values of from 30 to 40% and can be applied to solid oral medicaments with less solvent than conventional cellulose acetate phthalate polymers. Also provided is a process for preparing the low viscosity cellulose acetate phthalate polymers.

Abstract: A make-up cosmetic product, which enhances the appearance of complexion, is evaluated by irradiating lights having a wavelength range of visible light onto a surface on which the make-up cosmetic product is applied, from at least two directions with different incident angles, measuring a plurality of spectra of reflected lights obtained from the irradiated lights, respectively, and comparing the spectrum patterns with each other. This clarifies the optical theory by which the skin looks beautiful and provides a method for evaluating a make-up cosmetic product making the skin look beautiful.

Abstract: The present invention relates to a composition for topical use comprising a hydroxycarboxylic acid and oat extract. The present invention also relates to a method of enhancing the rate of skin desquamation by incorporating oat extract into a composition containing hydroxycarboxylic acid. The composition can be topically applied.

Abstract: Coatings for hard tissue and surfaces of the oral environment are provided that reduce adhesion of bacteria and proteinaceous substances to these surfaces. Methods of reducing adhesion of these materials to such surfaces, and polymers for incorporation into such coatings are also provided.

Abstract: The present invention provides for an antifungal, antibacterial and antiviral filter comprising in laminations a dust collecting filter and a filter impregnated with a tea extract. The filter having nonwoven fabric is impregnated with a polyphenol tea extract, which can be easily produced commercially and is capable of maintaining a high virus trapping performance, inactivating the trapped viruses and preventing them from being rescattered.

Abstract: The present invention relates to oral compositions having enhanced organoleptic characteristics of fattiness, creaminess, soothing, satisfaction, and full mouthfeel, and comprises acylglycerol compounds having substituents R.sub.1, R.sub.2, and R.sub.3 attached at the positions of the OH.sup.31 groups of a glycerol backbone. The substituents R.sup.1 and R.sub.2 are independently selected from conjugated polyunsaturated fatty acids having from 16 carbon atoms to 22 carbon atoms and R.sub.3 is selected from the group consisting of R.sub.1, OH, PO.sub.3 HR.sub.4, and C.sub.6 -C.sub.12 carboxylic acids, wherein R.sub.4 is selected from the group consisting of OH, choline, inositol, serine, and ethanolamine. The oral compositions of the present invention being substantially free of free conjugated polyunsaturated fatty acids.

Abstract: The wax combination for the cosmetic compositions contains from 2 to 70 percent by weight of apple wax; from 5 to 70 percent by weight of orange wax and/or citric wax; and from 10 to 70 percent by weight of jojoba oil. The cosmetic compositions advantageously contain a portion of the wax combination in free form or an effective ingredient complex consisting of capsules, each containing some of the wax combination.

Abstract: The present invention relates to a poison bait for controlling pest insects comprising (a) an insecticidally active ingredient, (b) a sauce for seasoning or a sauce spice flavor, (c) a vegetable oil and, if necessary, (d) at least one of grain powder, dextrin and sugar. The inventive poison bait controls pest insects such as cockroaches and the like based on feeding preference.

Abstract: It has long been the practice to treat the skin of individuals to clean and soften the skin with soaps and detergents. A compound containing glycerin, alcohol, jojoba oil, aloe vera, silk extracts, glyceryl monostearate, decyl oleate, propylene glycol, isopropyl palmitate, dimethicone, magnesium ascorbyl phosphate, sodium dodecyl sulfate, methyl paraben, xanthan gum, propyl paraben, and deionized water are formed into a silk cream composition in order to clean and soften skin. A lotion form of the compound that adds natural fragrances and mineral oil is also disclosed. A method of using the skin cream and or the lotion is also disclosed.

Abstract: The present invention provides a method of treating anxiety and related disorders using an agonist which acts at negatively coupled cAMP-linked metabotropic glutamate receptors.