Patents Examined by Danah Al-Awadi
  • Delayed-release formulation for reducing the frequency of urination and method of use thereof
    Patent number: 8445011
    Abstract: Methods and compositions for reducing the frequency of urination are disclosed. One method comprises administering to a subject in need thereof an effective amount of a pharmaceutical composition comprising an analgesic agent formulated in a delayed-release formulation. Another method comprises administering to a subject in need thereof an effective amount of a pharmaceutical composition comprising multiple active ingredients. Yet another method comprises administering to a subject in need thereof an effective amount of a diuretic followed with another administration of an pharmaceutical composition comprising an analgesic agent.
    Type: Grant
    Filed: July 27, 2012
    Date of Patent: May 21, 2013
    Assignee: Wellesley Pharmaceuticals, LLC
    Inventor: David A. Dill
  • Coated medical devices for abluminal drug delivery
    Patent number: 8431149
    Abstract: The invention relates generally to an implantable medical device for delivering a therapeutic agent to the body tissue of a patient, and a method for making such a medical device. In particular, the invention pertains to an implantable stent, such as an intravascular stent, having a coating comprising an inorganic or ceramic oxide, metal or inert carbon and a plurality of reservoirs in such material that contain a therapeutic agent.
    Type: Grant
    Filed: February 27, 2008
    Date of Patent: April 30, 2013
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: David McMorrow, Barry Heaney, Anthony Malone, Aiden Flanagan, Tim O'Connor
  • Cyclodepsipeptides with antineoplastic activity and methods of using to inhibit cancer and microbial growth
    Patent number: 8415294
    Abstract: The present invention is directed to cyclodepsipeptide compounds having antineoplastic and/or antimicrobial activity, preferably Kitastatin 1. The present invention is further directed to methods of inhibiting cancer cell growth and/or microbial growth in a host inflicted therewith by administering cyclodepsipeptide compounds to the inflicted host.
    Type: Grant
    Filed: June 5, 2008
    Date of Patent: April 9, 2013
    Assignee: Arizona Board of Regents
    Inventors: George R. Pettit, Rui Tan, Robin K. Pettit
  • Oral particle compositions containing a core and an acid-soluble coat
    Patent number: 8399011
    Abstract: The present invention relates to an oral particle composition as an ingredient in an extended-release tablet formulation, comprising a core and a coat, wherein the coat is acid-soluble.
    Type: Grant
    Filed: August 10, 2012
    Date of Patent: March 19, 2013
    Assignee: Magnifica Inc.
    Inventors: David Wong, James A Lee
  • Dry hemostatic compositions and methods for their preparation
    Patent number: 8383141
    Abstract: Dry cross-linked gelatin compositions are prepared that rapidly re-hydrate to produce gelatin hydrogels suitable as hemostatic sealants. Gelatin is cross-linked in the presence of certain re-hydration aids, such as polyethylene glycol, polyvinylprovidone, and dextran, in order to produce a dry cross-linked gelatin powder. The use of the re-hydration aids has been found to substantially increase the re-hydration rate in the presence of an aqueous re-hydration medium, typically thrombin-containing saline.
    Type: Grant
    Filed: July 21, 2008
    Date of Patent: February 26, 2013
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Zhen Qian, A. Edward Osawa, Cary J. Reich
  • Preparation and use of sleeve and micro-encapsulated topical analgesic patch for treating pain
    Patent number: 8367100
    Abstract: Novel micro-encapsulated topical analgesics are provided to treat pain and may be applied via sleeves having dosed therapeutic sections, especially to joints and extremities. Sleeves may be prepared and packaged inside-out and inverted when positioned by the wearer.
    Type: Grant
    Filed: August 24, 2010
    Date of Patent: February 5, 2013
    Assignee: Chattem, Inc.
    Inventors: Shane C Smith, Joseph Czerwinski, Mike Davies, Don Moak, Blair Ramey
  • Method for modifying the wettability and/or other biocompatibility characteristics of a surface of a biological material by the application of gas cluster ion beam technology and biological materials made thereby
    Patent number: 8367092
    Abstract: The invention provides methods for surgical grafting of a tissue. The method comprises the steps of explanting a graft tissue from a donor, irradiating at least a first portion of the graft tissue with an ion beam, and surgically grafting the graft tissue into a recipient.
    Type: Grant
    Filed: March 11, 2010
    Date of Patent: February 5, 2013
    Assignee: Exogenesis Corporation
    Inventors: Joseph Khoury, Laurence B. Tarrant, Sean R. Kirkpatrick, Richard C. Svrluga
  • Implantable drug delivery devices having alternating hydrophilic and amphiphillic polymer layers
    Patent number: 8343529
    Abstract: An implantable drug delivery medical device with alternating hydrophilic and amphiphilic polymer layers and methods of using for the treatment of vascular disease are disclosed.
    Type: Grant
    Filed: May 17, 2012
    Date of Patent: January 1, 2013
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Syed F. A. Hossainy, Mikael O. Trollsas, Lothar W. Kleiner
  • Process of manufacturing a solid cosmetic product
    Patent number: 8337894
    Abstract: A process of manufacturing a solid cosmetic product, includes the steps of applying to a composition based on powder and fluid binder, introduced into a mould, a sheet of porous material having an average pore diameter ranging from 5 to 180 ?m; then passing at least some of the volatile solvent through the sheet; removing the volatile solvent that has passed through the sheet and drying the composition in order to solidify it before depositing it in a packaging. The solid product obtained according to this process and to its uses as a face and/or body makeup product are also described.
    Type: Grant
    Filed: June 25, 2008
    Date of Patent: December 25, 2012
    Assignee: Chanel Parfums Beaute
    Inventors: Nadine Goetz, Blandine Hingant, Christian Salciarini, Jean-Luc Lambrecq, Michel Siodmak, Michele Mousset, Marie-Anne Sanchez, Helene De Clermont Gallerande
  • Reduction of infection associated with medical device
    Patent number: 8337877
    Abstract: Anti-infective articles capable of preventing infection associated with implantation of medical devices include low levels of anti-infective agents, may cover only a fraction of the portion of the medical device and be effective, or may rapidly elute anti-infective agent, without sustained elution, and still be effective.
    Type: Grant
    Filed: April 11, 2011
    Date of Patent: December 25, 2012
    Assignee: Medtronic, Inc.
    Inventors: Thomas C. Bischoff, William V. Ferris, Jr.
  • Flexible, compressed intravaginal rings, methods of making and using the same, and apparatus for making the same
    Patent number: 8323679
    Abstract: The present invention is directed to flexible, compressed intravaginal rings comprising a substantially homogeneous compressed mixture comprising a polymethacrylate, a plasticizer, and an active agent, and methods of making and using the same, and apparatus for making the same.
    Type: Grant
    Filed: January 5, 2011
    Date of Patent: December 4, 2012
    Assignee: TEVA Women's Health, Inc.
    Inventors: Salah U. Ahmed, Tahseen A. Chowdhury, Yi Luo
  • Poly(ester-amide) and poly(amide) coatings for implantable medical devices for controlled release of a protein or peptide and a hydrophobic drug
    Patent number: 8323676
    Abstract: This invention is generally related to coatings for implantable medical devices, such as drug delivery vascular stents. The coating includes a drug reservoir layer above the outer surface of the device body, the drug reservoir layer with a peptide or protein, a hydrophobic drug, and a polymer with a weight average molecular weight between about 10,000 to about 150,000 Daltons. A preferred polymer is a poly(ester amide) polymer.
    Type: Grant
    Filed: June 30, 2008
    Date of Patent: December 4, 2012
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Florencia Lim, Mikael O. Trollsas, Xinmin Xu, Bozena Zofia Maslanka
  • Drug delivery system for the prevention of cerebral vasospasm
    Patent number: 8303974
    Abstract: The present invention relates to the treatment and prevention of vasospasm. The present invention provides a system for treating a cerebral vasospasm in a human utilizing a pharmaceutical composition and administrating a therapeutically effective amount of the pharmaceutical composition to a predetermined location in close proximity to a cerebral artery within a subarachnoid space wherein the pharmaceutical composition produces a localized pharmacologic effect thereby treating the cerebral vasospasm.
    Type: Grant
    Filed: June 11, 2008
    Date of Patent: November 6, 2012
    Assignee: Edge Therapeutics, Inc.
    Inventors: R. Loch Macdonald, Brian Leuthner
  • Use of long carbon chain quaternary ammonium salt phosphoric acid ester as conditioner for hair
    Patent number: 8293219
    Abstract: Use of long carbon chain quaternary ammonium salt phosphoric acid ester of formula (I) as conditioner for hair.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: October 23, 2012
    Assignee: Nanjing Huashi Chemical Co., Ltd
    Inventors: Changguo Wang, Evelyn Su
  • Sleeve and micro-encapsulated topical analgesic for pain relief
    Patent number: 8282607
    Abstract: Novel micro-encapsulated topical analgesics are provided to treat pain and may be applied via sleeves having dosed therapeutic sections, especially to joints and extremities. Sleeves may be prepared inside-out and inverted when positioned by the wearer.
    Type: Grant
    Filed: May 13, 2004
    Date of Patent: October 9, 2012
    Assignee: Chattem, Inc.
    Inventors: Shane C Smith, Joseph Czerwinski, Mike Davies, Don Moak, Blair Ramey
  • Polymer nanofilm coatings
    Patent number: 8263104
    Abstract: Disclosed herein are nanofilm coatings for implantable medical devices comprising a diblock or triblock copolymer (PEO-PMMA or PMOXA-PDMS-PMOXA, respectively). Such nanofilms, may be used, for example, as amphiphilic supports for therapeutic agents. These materials are conducive towards the formation of active substrates for a suite of biological and medical applications.
    Type: Grant
    Filed: June 9, 2008
    Date of Patent: September 11, 2012
    Assignees: Northwestern University, The Regents of the University of California
    Inventors: Dean Ho, Mark Chen, Erik Pierstorff, Houjin Huang, Edward K Chow, Genhong Cheng
  • Methods and compositions to treat hemorrhagic conditions of the brain
    Patent number: 8252302
    Abstract: The described invention provides a nonhuman animal model system for hemorrhagic brain conditions, methods for evaluating a substance for treating the hemorrhagic brain condition in a mammal, methods for treating hematoma expansion or recurrent rebleeding resulting from hemorrhagic brain conditions in a mammal, and pharmaceutical compositions for administration into or at a distance proximal to the hemorrhagic brain condition.
    Type: Grant
    Filed: February 22, 2011
    Date of Patent: August 28, 2012
    Assignee: Edge Therapeutics, Inc.
    Inventor: R. Loch Macdonald
  • Multi-polymer hydrogels
    Patent number: 8236342
    Abstract: The invention provides a multi-polymer hydrogel article having a first polymeric, water-swellable material and a second polymeric material, organized such that a first region substantially comprises the first polymeric, water-swellable material, a second region adjacent the first region comprises a mixture of the first polymeric, water-swellable material and the second polymeric material, and a third region adjacent the second region substantially comprises the second polymeric material. The article exhibits an increasing concentration gradient of the second polymeric material moving from the first region, through the second region, to the third region.
    Type: Grant
    Filed: April 26, 2010
    Date of Patent: August 7, 2012
    Assignee: Zimmer, Inc.
    Inventors: Brian Thomas, Kai Zhang
  • Particle stabilised emulsion composition
    Patent number: 8236332
    Abstract: The present invention relates to emulsifier system comprising food-grade gelled particles and the preparation of particle stabilised emulsions with this emulsifier. The emulsifier system can be used in any fields of applications, such as food products, home and personal care applications and pharmaceutical applications.
    Type: Grant
    Filed: September 23, 2008
    Date of Patent: August 7, 2012
    Assignee: Conopco Inc.
    Inventor: Nicholas David Hedges
  • Endosseous implant
    Patent number: RE43793
    Abstract: Endosseous implant to be applied to a human or animal bone, wherein the surface of the implant is made from titanium or a titanium alloy, said implant having a smooth or rough surface texture, which is characterized in that said surface has been treated with at least one selected organic phosphonate compound or a pharmaceutically acceptable salt or ester or an amide thereof; process for producing said implants.
    Type: Grant
    Filed: November 19, 2001
    Date of Patent: November 6, 2012
    Assignees: Universite de Geneve, Ecole Polytechnique Federale de Lausanne
    Inventors: Pierre Descouts, Bjorn-Owe Aronsson, Michael Gratzel, Carine Viorney, Peter Pechy