Patents Examined by Daniel F Coughlin
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Patent number: 8999376Abstract: Tissue patches and associated systems and methods are described. Certain embodiments are related to inventive systems and methods in which tissue patches can be made quickly and robustly without the use of complicated fabrication or sterilization equipment.Type: GrantFiled: October 4, 2012Date of Patent: April 7, 2015Assignee: Xcede Technologies, Inc.Inventor: Daniel Grant Ericson
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Patent number: 8992890Abstract: The invention discloses pharmaceutical compositions in the form of a dusting powder or dry spray, possessing a high absorbent capacity, painkilling activity and wound-healing action, which compositions consist of croscarmellose sodium, a non-steroidal anti-inflammatory drug (NSAID) and hyaluronic acid, and optionally also contain other pharmacologically active substances and/or excipients. The compositions disclosed herein are suitable for use in the treatment of skin lesions wherein the presence of exudate limits wound healing and causes pain; they are therefore particularly suitable for chronic ulcerous skin lesions of various origins and burns.Type: GrantFiled: February 13, 2012Date of Patent: March 31, 2015Assignee: Fidia Farmaceutici S.p.A.Inventors: Andrea Pastorello, Devis Galesso, Fabio Bettella
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Patent number: 8978666Abstract: A method for reducing irritation on an intimate area comprising: applying an intimate cleansing product to the intimate area; rinsing the intimate cleansing product from the intimate area; applying a shave preparation to the intimate area; shaving the intimate area; wherein the intimate cleansing product comprises a malodor active.Type: GrantFiled: February 16, 2011Date of Patent: March 17, 2015Assignee: The Procter & Gamble CompanyInventor: James Robert Schwartz
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Patent number: 8940324Abstract: The invention relates to octenidine or a pharmaceutical salt thereof, in particular octenidine dihydrochloride, which is intended for mutual therapeutic administration of the octenidine in solution with a polyalcohol of formula 1: (H—C—OH)a(HO—C—OH)b(H—C—H)c, where a, b, c are whole numbers, where a+b is at least 2, preferably at least 3, c is selected from 0, 1 or a number from 2 to a+b, optionally in addition to one or more aldehyde groups provided that they form (cyclic) acetals with one of the hydroxy groups or one or more keto groups optionally as acetal with one of the hydroxy groups, optionally in addition to one or more carboxylic acid groups if the polyalcohol is a cyclic acetal or acetal, preferably with ring sizes of 5 to 7 atoms, or a polymer, polyether or polyester thereof, provided that the polyalcohol exists as a polymer, polyether or polyester with at least two units of formula 1 if a+b is 2 or 3.Type: GrantFiled: November 13, 2009Date of Patent: January 27, 2015Assignee: Artan Holding AGInventor: Ahmet Melih Aydinoglu
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Patent number: 8906408Abstract: The invention relates to octenidine or a pharmaceutical salt thereof, in particular octenidine dihydrochloride, which is intended for mutual therapeutic administration of the octenidine in solution with a polyalcohol of formula 1: (H—C—OH)a(HO—C—OH)b(H—C—H)c, where a, b, c are whole numbers, where a+b is at least 2, preferably at least 3, c is selected from 0, 1 or a number from 2 to a+b, optionally in addition to one or more aldehyde groups provided that they form (cyclic) acetals with one of the hydroxy groups or one or more keto groups optionally as acetal with one of the hydroxy groups, optionally in addition to one or more carboxylic acid groups if the polyalcohol is a cyclic acetal or acetal, preferably with ring sizes of 5 to 7 atoms, or a polymer, polyether or polyester thereof, provided that the polyalcohol exists as a polymer, polyether or polyester with at least two units of formula 1 if a+b is 2 or 3.Type: GrantFiled: November 13, 2009Date of Patent: December 9, 2014Assignee: Artan Holding AGInventor: Ahmet Melih Aydinoglu
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Patent number: 8889178Abstract: Bioactive porous bone graft implants in various forms suitable for use in bone tissue regeneration and/or repair, as well as methods of use are provided. The implants are formed of bioactive glass and have an engineered porosity. The implants may be contained in polymer for enhanced clinical results and better handling.Type: GrantFiled: March 14, 2013Date of Patent: November 18, 2014Assignee: Prosidyan, IncInventors: Charanpreet S. Bagga, Steve B. Jung, Hyun W. Bae
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Patent number: 8883195Abstract: Bioactive porous bone graft implants in various forms suitable for bone tissue regeneration and/or repair, as well as methods of use, are provided. The implants are formed of bioactive glass and have an engineered porosity. The implants may take the form of a putty, foam, fibrous cluster, fibrous matrix, granular matrix, or combinations thereof and allow for enhanced clinical results as well as ease of handling.Type: GrantFiled: March 14, 2013Date of Patent: November 11, 2014Assignee: Prosidyan, Inc.Inventors: Charanpreet S. Bagga, Steve B. Jung, Hyun W. Bae
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Patent number: 8865777Abstract: A kit for producing bone cement includes at least one paste A and one paste B. Paste A contains at least one monomer (a1) for radical polymerization; at least one polymer (a2) insoluble in monomer (a1); at least one polymer (a3) soluble in monomer (a1); and at least one radical polymerization initiator (a4). The weight ratio of the at least one polymer (a2) to the at least one polymer (a3) is at least 2 to 1. Paste B contains at least one monomer (b1) for radical polymerization; at least one polymer (b2) and at least one accelerator (b3) soluble in monomer (b1); and optionally a polymer (b4) insoluble in monomer (b1). The maximum quantity of polymer (b4) is 5% by weight, relative to the total weight of paste B. The weight ratio of polymer (b4) to the at least one polymer (b2) is no more than 0.2.Type: GrantFiled: July 26, 2012Date of Patent: October 21, 2014Assignee: Heraeus Medical GmbHInventors: Sebastian Vogt, Hubert Büchner
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Patent number: 8821942Abstract: A calcium carbonate granulation and a method for preparing a calcium carbonate granulation are provided. The method includes applying an atomized binder to powdered calcium carbonate in a fluid bed granulator at a relatively high atomization pressure to achieve a reduced binder droplet size, and drying the resulting composition at elevated temperatures in a fluidized bed dryer. The resulting granulation include porous granules having a lower density and reduced mean particle size with improved compressibility. In addition, the resulting granulation can be compacted into tablets having a hardness 50% greater than the hardness of tablets formed from commercially available granulations.Type: GrantFiled: April 5, 2012Date of Patent: September 2, 2014Assignee: Access Business Group International LLCInventors: David S. Chang, Huoy-Jiun Jean Wang
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Patent number: 8790709Abstract: Compositions and methods for delivering bioactive agents, such as vitamins, hormones, nutrients and drugs, by stabilizing and or solubilizing these agents in a polymer matrix. The carrier polymers can be used in drug delivery and are useful for delivery of small molecules. The carrier polymers also can be used in scaffolds for regenerative medicine.Type: GrantFiled: June 17, 2011Date of Patent: July 29, 2014Assignee: Polytechnic Institute of New York UniversityInventors: Jin Kim Montclare, Man Xia Lee, Jennifer Haghpanah
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Patent number: 8784877Abstract: Described are transdermal drug delivery systems for the transdermal administration of levonorgestrel, comprising a polymer matrix and levonorgestrel acetate. Methods of making and using such systems also are described.Type: GrantFiled: December 27, 2011Date of Patent: July 22, 2014Assignee: Noven Pharmaceuticals, Inc.Inventors: David W. Houze, Vincent Lau Chan
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Patent number: 8758818Abstract: Oral tablet compositions of dexlansoprazole or pharmaceutically acceptable salts or hydrated forms thereof having a gradual release and processes for the manufacture of the tablet composition and its use in the treatment of gastrointestinal disorders.Type: GrantFiled: September 23, 2013Date of Patent: June 24, 2014Assignee: Sanovel Ilac Sanayi ve Ticaret Anonim SirketiInventors: Umit Cifter, Ali Turkyilmaz, Ibrahim Murat Uzer, Alper Terkinli, Levent Oner
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Patent number: 8754134Abstract: Disclosed are compositions that include treated biodiesel glycerin. The disclosed compositions may be utilized as soil-amendments for controlling pests, weeds and for enhancing growth of plants. The biodiesel glycerin utilized in the disclosed compositions may be treated by one or more steps including neutralization, heating, refluxing, condensing, and distilling.Type: GrantFiled: March 15, 2013Date of Patent: June 17, 2014Assignee: Auburn UniversityInventors: Robert H. Walker, Rodrigo Rodríguez-Kábana
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Patent number: 8753682Abstract: Dual release oral tablet compositions of dexlansoprazole or pharmaceutically acceptable salts or hydrated forms thereof and processes for the manufacture of the tablet composition and its use in the treatment of gastrointestinal disorders.Type: GrantFiled: September 23, 2013Date of Patent: June 17, 2014Assignee: Sanovel Ilac Sanayi ve Ticaret Anonim SirketiInventors: Umit Cifter, Ali Turkyilmaz, Ibrahim Murat Uzer, Alper Terkinli, Levent Oner
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Patent number: 8741345Abstract: Modified release oral pharmaceutical compositions of dexlansoprazole or pharmaceutically acceptable salts or hydrated forms thereof in the form of a bilayer tablet and processes for the manufacture of the tablet composition and its use in the treatment of gastrointestinal disorders.Type: GrantFiled: May 5, 2011Date of Patent: June 3, 2014Assignee: Sanovel ILAC Sanayi Ve Ticaret Anonim SirketiInventors: Umit Cifter, Ali Turkyilmaz, Ibrahim Murat Uzer, Alper Terkinli, Levent Oner
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Patent number: 8741318Abstract: One aspect of the present invention relates to a method of synthesizing a multicomponent and biocompatible nanocomposite material, which includes: synthesizing a gold/hydroxyapatite (Au/HA) catalyst; distributing the Au/HA catalyst into a thin film; and heating the thin film in a reactor with a carbon source gas to perform radio frequency chemical vapor deposition (RF-CVD) to form the nanocomposite material, where the nanocomposite material includes a graphene structure and Au/HA nanoparticles formed by the Au/HA catalyst and distributed within the graphene structure. In another aspect, a multicomponent and biocompatible nanocomposite material includes: a graphene structure formed with a plurality of graphene layers and Au/HA nanoparticles distributed within the graphene structure. The nanocomposite material is formed by heating an Au/HA catalyst thin film with a carbon source gas to perform radio frequency chemical vapor deposition (RF-CVD).Type: GrantFiled: August 30, 2012Date of Patent: June 3, 2014Assignee: Board of Trustees of the University of ArkansasInventors: Alexandru S. Biris, Alexandru R. Biris
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Patent number: 8728546Abstract: The invention provides a medicament for the treatment of cancer, cardiovascular diseases and/or inflammation. The medicament may be administered orally, parenterally or topically.Type: GrantFiled: March 15, 2013Date of Patent: May 20, 2014Assignee: Swing Aerobics Licensing, Inc.Inventor: Brian Peskin
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Patent number: 8716279Abstract: The present invention includes benzodiazepine compositions formulated for intranasal administration, comprising a binary solvent system comprising a first solvent in which the benzodiazepine is soluble, the first solvent capable of penetrating nasal mucosal tissue, and a second solvent in which the benzodiazepine in less soluble. The compositions of the present invention may be used to treat a variety of disorders including, but not limited to, panic attacks, muscle spasms, anxiety, and seizures. In one aspect, the present invention relates to a fast-acting, clonazepam composition for transnasal administration that can be used for the treatment of seizure clusters.Type: GrantFiled: August 27, 2007Date of Patent: May 6, 2014Assignee: Jazz Pharmaceuticals, Inc.Inventors: Gene Jamieson, Michael Des Jardin, Clark Allphin, Sigridur Olafsdottir
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Patent number: 8710105Abstract: A method of preparing enteric hard capsules, and an enteric hard capsule prepared by the method. The method may include: dissolving an enteric base material, a capsule forming aid, and a neutralizing agent in water at room temperature to prepare an aqueous composition; heating the aqueous composition to a first temperature that is higher than a gelation start temperature of the aqueous composition; cooling the heated aqueous composition to a second temperature that is lower than the gelation start temperature; immersing a mold pin heated to a third temperature that is higher than the gelation start temperature into the aqueous composition; removing the mold pin from the aqueous composition to obtain a film coated on the mold pin; maintaining the film on the mold pin at a fourth temperature that is higher than the gelation start temperature for a first time period to fix the film onto the mold pin; and drying the fixed film at a fifth temperature for a second time period to obtain a capsule shell.Type: GrantFiled: February 21, 2011Date of Patent: April 29, 2014Assignee: Samsung Fine Chemicals Co., Ltd.Inventors: Jin Ryul Son, Hyon Ho Baek, Eun Hee Park, Sung Wan Lee, Min Gyu Song, Ja Hyun Cha, Jae Uk Cha, Won Hwa Ko
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Patent number: 8703187Abstract: New dosage forms of vitamin D and calcium carbonate having improved content uniformity are described. The improvements are realized through modifications to the formulation, the raw material specifications, and the process of manufacture.Type: GrantFiled: April 24, 2008Date of Patent: April 22, 2014Assignee: Warner Chilcott Company, LLCInventors: Gregory Paul Dittmar, Andrew Irvine Sokolik