Patents Examined by Danielle B Henkel
  • Patent number: 10760042
    Abstract: The present invention is directed to a method and automated transfer means for transferring a container within an apparatus. The apparatus of the present invention may include a means for automated loading, a means for automated transfer and/or a means for automated unloading of a container (e.g., a specimen container). In one embodiment, the apparatus can be an automated detection apparatus for rapid non-invasive detection of a microbial agent in a test sample. The detection system also including a heated enclosure, a holding means or rack, and/or a detection unit for monitoring and/or interrogating the specimen container to detect whether the container is positive for the presence of a microbial agent. In other embodiment, the automated instrument may include one or more, bar code readers, scanners, cameras, and/or weighing stations to aid in scanning, reading, imaging and weighing of specimen containers within the system.
    Type: Grant
    Filed: September 1, 2015
    Date of Patent: September 1, 2020
    Assignee: bioMerieux, Inc.
    Inventors: James Clement Bishop, Mark Joseph Fanning, Lawrence E Guerra
  • Patent number: 10736314
    Abstract: The invention provides, in various embodiments, systems, devices and methods relating to ex-vivo organ care. In certain embodiments, the invention relates to maintaining an organ ex-vivo at near-physiologic conditions. The present application describes a method for using lactate measurement in the arterial and the venous blood lines of the Organ Care System Heart perfusion device to evaluate the: 1) The overall perfusion status of an isolated heart and 2) The metabolic status of an isolated heart and 3) the overall vascular patency of an isolated donor heart. This aspect of the present invention uses the property of myocardial cell's unique ability to produce/generate lactate when they are starved for oxygen and metabolize/utilize lactate for energy production when they are well perfused with oxygen.
    Type: Grant
    Filed: April 26, 2019
    Date of Patent: August 11, 2020
    Assignee: TRANSMEDICS, INC.
    Inventors: Waleed H. Hassanein, Tamer I. Khayal, Ahmed Elbetanony, Paul Lezberg, Giovanni Cecere, Dennis Sousa, Elizabeth (Hansen) Bulger
  • Patent number: 10738270
    Abstract: Microfluidic devices and methods for perfusing a cell with perfusion fluid are provided herein, wherein the gravitational forces acting on the cell to keep the cell at or near a retainer or a retaining position exceed the hydrodynamic forces acting on the cell to move it toward an outlet. Also provided, are methods for assaying cell products within the microfluidic device.
    Type: Grant
    Filed: March 13, 2020
    Date of Patent: August 11, 2020
    Assignee: The University of British Columbia
    Inventors: Carl L. G. Hansen, Veronique Lecault, James M. Piret, Anupam Singhal
  • Patent number: 10738269
    Abstract: An algal growth system includes a first flexible sheet material mounted on a first frame in a first mounted geometry having a first height and a first width, the first height being greater than the first width, and a second flexible sheet material mounted on a second frame in a second mounted geometry having a second height and a second width, the second height being greater than the second width. The first flexible sheet and the second flexible sheet material are noncontiguous. The algal growth system also includes a motor, the motor being coupled with an actuator system, where the motor actuates the actuator system, and a reservoir.
    Type: Grant
    Filed: September 30, 2019
    Date of Patent: August 11, 2020
    Assignees: Gross-Wen Technologies, Inc., Iowa State University Research Foundation, Inc.
    Inventors: Martin Anthony Gross, Zhiyou Wen
  • Patent number: 10731120
    Abstract: The present invention discloses a flow electroporation device comprising a three-dimensional electrode device and a flow electroporation chamber, the three-dimensional electrode device comprising an electrode array and an electrode fixing assembly for fixing electrodes in the electrode array, the flow electroporation chamber comprising a cavity, an inlet, an outlet and an opening, the inlet, the outlet and the opening on the cavity, and the electrode array being inserted into the cavity through the opening By means of the above-mentioned manner, the flow electroporation device of the present invention can achieve a high throughput cell treatment, and also can work under a low voltage condition, can avoid damages to cells brought by liquid flow, can reduce effects brought by heat and cathode effect induced by electric pulses, and can maintain an closed aseptic environment.
    Type: Grant
    Filed: November 11, 2014
    Date of Patent: August 4, 2020
    Assignee: ETTA BIOTECH CO., LTD.
    Inventor: Edward Dai
  • Patent number: 10730013
    Abstract: A system for removing undesirable compounds from contaminated air includes a biofilter having porous glass media. Hydrogen sulfide is removed from contaminated air by passing the contaminated air through the biofilter.
    Type: Grant
    Filed: October 19, 2018
    Date of Patent: August 4, 2020
    Assignee: Evoqua Water Technologies LLC
    Inventor: Timothy Frank Matheis
  • Patent number: 10723989
    Abstract: The invention relates to a container device (1), comprising: a container receiving portion (4) for receiving a container; at least one valve (6) for controlling a flow of fluid in a fluid line connected to said container; a pump device (8) for generating a conveyor pressure of the fluid in the fluid line; a control device (10) which can be connected to the valve (6) and/or the pump device (8) in order to control the valve (6) and/or pump device (8); and a frame (2) which supports said container receiving portion (4), valve (6), pump device (8) and control device (10).
    Type: Grant
    Filed: May 12, 2016
    Date of Patent: July 28, 2020
    Assignee: Sartorius Stedim Biotech GmbH
    Inventors: Jan Schaefer, Christian Manzke, Etienne Evrard
  • Patent number: 10717961
    Abstract: A cell culture system having a cell culture vessel, a composition controlling fluid storage vessel, a culture fluid composition controlling means having an inlet and an outlet for a cell culture fluid, an inlet-connected fluid feeding circuit from the cell culture vessel to the inlet of the culture fluid composition controlling means, an outlet-connected fluid feeding circuit from the cell culture vessel to the outlet of the culture fluid composition controlling means, a means which perfuses the cell culture fluid from the inlet-connected fluid feeding circuit to the outlet-connected fluid feeding circuit through the culture fluid composition controlling means, and a means which controls the amount of fluid in the cell culture vessel, in which compositions of the cell culture fluid in the cell culture vessel and compositions of the composition controlling fluid in the composition controlling fluid storage vessel can be controlled in a continuous manner.
    Type: Grant
    Filed: April 24, 2013
    Date of Patent: July 21, 2020
    Assignees: ASAHI KASEI KABUSHIKI KAISHA, TOKYO WOMEN'S MEDICAL UNIVERSITY
    Inventors: Ushio Iwamoto, Michi Sato, Kanako Konishi, Katsuhisa Matsuura, Tatsuya Shimizu, Teruo Okano
  • Patent number: 10703683
    Abstract: A facility for treating and recycling animal waste (2), including a unit (6) for methanizing the waste including treatment of the obtained biogases, a cogeneration unit (8) delivering electricity and heat (32) from the biogases, and a unit for hydroponically cultivating microalgae (14) in photo-bioreactors supplied by the liquid phase (12) of the organic residues from the methanization. The facility further includes a unit for cultivating macrophytes (22) supplied with water (20) leaving the unit for cultivating microalgae, and a vermiculture unit (24) fed by harvesting the macrophytes (22) and by the sludge (36) coming from the raw digestate from the methanization.
    Type: Grant
    Filed: June 30, 2014
    Date of Patent: July 7, 2020
    Assignee: SKYWORLD INTERNATIONAL OVERSEAS LIMITED
    Inventor: René-Jean Guillard
  • Patent number: 10704018
    Abstract: Microfluidic devices and methods for perfusing a cell with perfusion fluid are provided herein, wherein the gravitational forces acting on the cell to keep the cell at or near a retainer or a retaining position exceed the hydrodynamic forces acting on the cell to move it toward an outlet. Also provided, are methods for assaying cell products within the microfluidic device.
    Type: Grant
    Filed: July 30, 2019
    Date of Patent: July 7, 2020
    Assignee: THE UNIVERSITY OF BRITISH COLUMBIA
    Inventors: Carl L. G. Hansen, Veronique Lecault, James M. Piret, Anupam Singhal
  • Patent number: 10683476
    Abstract: A bioreactor system for preparing a cardiac organoid chamber and for subsequent testing thereof is described herein and shown in the exemplary drawing figures. The bioreactor system includes a first vessel having a hollow interior and an open top. A first cover is mated with the open top of the first vessel. The first cover has a first opening formed therein. The system further includes a cannula having a lumen that extends from an open first end to an open second end. The cannula is disposed within the first opening of the first cover such that a portion of the cannula lies below the first cover and for insertion into the hollow interior of the first vessel. A porous ring is coupled to the cannula at or proximate the open second end thereof. The system also includes a balloon catheter having an inflatable balloon at a distal end of a catheter shaft. The balloon catheter is adapted to pass through the lumen of the cannula when the balloon is in a deflated state.
    Type: Grant
    Filed: May 29, 2015
    Date of Patent: June 16, 2020
    Assignee: Icahn School of Medicine at Mount Sinai
    Inventors: Kevin David Costa, Timothy James Cashman, Peter Constantine Backeris
  • Patent number: 10676705
    Abstract: The invention provides an automated apparatus of cell culture having tanks of culture medium, of growth factors and of cells to be cultured, an incubator having a thermostated enclosure which houses a cell culture vessel, and control computer system. A supporting and agitation device of the culture vessel is provided in the enclosure, and the culture vessel is formed by a bag having at least one inlet port connected to the tanks and one outlet port connected devices for harvesting and storage of the cells after culture, these harvesting and storage devices and tanks being located outside the enclosure and being connected to the cell expansion bag ports by conduits which together with the cell expansion bag form a preassembled module passing through a wall of the enclosure.
    Type: Grant
    Filed: June 8, 2012
    Date of Patent: June 9, 2020
    Assignee: CELLPROTHERA
    Inventors: Philippe Henon, Claire Saucourt, Patrick Gasse, Alain Sundas, Pierre Sugranes, Amandine Verdier, Frederic Demonchy
  • Patent number: 10669517
    Abstract: The present invention relates to an apparatus and a method that can accelerate reproduction of odor from an air-conditioner by segmenting microorganisms, a temperature/humidity condition and nutrients for metabolism of the microorganisms as conditions for reproducing the odor from the air-conditioner and setting the segmented microorganisms, a temperature/humidity condition and nutrients for metabolism of the microorganisms according to an accelerated condition thereof.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: June 2, 2020
    Assignees: Hyundai Motor Company, Kia Motors Corporation
    Inventors: Tae Hee Lee, Ki Young Yoon, Jae Sik Choi, Ji Wan Kim, So Yoon Park
  • Patent number: 10663989
    Abstract: A micro channel device processing apparatus includes a heating/cooling chamber configured to receive at least a sub-portion of a micro channel device and a fluid control system that controls a flow of a heating/cooling fluid in the chamber. A method includes controlling a temperature of a sample carried by a micro channel device installed in a micro channel device processing apparatus via a heating/cooling chamber of the processing apparatus. A micro channel device processing apparatus includes a heating/cooling chamber configured to receive a micro channel device carrying a sample and means for controlling a temperature of the sample in the chamber.
    Type: Grant
    Filed: September 6, 2018
    Date of Patent: May 26, 2020
    Assignee: Analogic Corporation
    Inventor: Louis Poulo
  • Patent number: 10655159
    Abstract: A locating method and system of determining a microorganism concentration of a fluid in a Petri dish is disclosed. The Petri dish includes a culture medium on which a seeding device is rotatable relative to the Petri dish. The seeding device distributes the fluid and includes at least one point of contact with the culture medium. The point of contact is associated with a contact zone.
    Type: Grant
    Filed: March 11, 2019
    Date of Patent: May 19, 2020
    Assignee: BIOMERIEUX
    Inventors: Laurent Drazek, Corine Fulchiron, Frederic Pinston, Herve Rostaing
  • Patent number: 10626358
    Abstract: The present invention provides for methods and at least partially automated devices suitable for producing a transplantable cellular suspension of living tissue suitable for promoting tissue regeneration in an epithelium-related procedure, as well as compositions produced therefrom. Tissue regeneration in humans is extremely limited and constitutes a major challenge to the repair of damaged organ function. Wound treatment is a typical area where tissue regeneration is required. Wounds (lacerations or openings) in mammalian tissue can result in tissue disruption and coagulation of the microvasculature at the wound face.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: April 21, 2020
    Assignee: AVITA MEDICAL LTD
    Inventors: Andrew Perry Quick, David Allen Fencil, William Ford Dolphin
  • Patent number: 10610910
    Abstract: A waste disposal apparatus for disposing of waste materials using aerobic decomposition includes a decomposition chamber, a waste inlet configured to admit waste materials into the decomposition chamber, a water feed system configured for supplying feed water to the decomposition chamber and a drain system configured for draining drain liquid from the decomposition chamber. The apparatus also includes a sensing system configured to sense the volume VF of feed water supplied to the decomposition chamber and the volume VD of drain liquid drained from the decomposition chamber, and a computing device that is configured to determine the quantity of waste material processed by the waste disposal apparatus from the sensed volumes VF and VD.
    Type: Grant
    Filed: January 20, 2015
    Date of Patent: April 7, 2020
    Assignee: Mechline Developments Limited
    Inventor: Peter Sage-Passant
  • Patent number: 10611993
    Abstract: A multichannel in-vitro metabolism real-time monitoring apparatus includes a radiation probing apparatus and a constant flow culture apparatus. The constant flow culture apparatus includes a liquid supply bottle, a waste liquid bottle, a multichannel infusion apparatus, and a multichannel liquid separation apparatus. The radiation probing apparatus has two groups of probing modules with flat structures, which are separately disposed on two sides of multichannel biochemical culture apparatuses and are used for recording radiation activities in the multichannel biochemical culture apparatuses in real time.
    Type: Grant
    Filed: February 27, 2014
    Date of Patent: April 7, 2020
    Assignee: Raycan Technology Co., Ltd. (Suzhou)
    Inventors: Gang Huang, Xiaoke Wu, Luyao Wang, Jun Zhu, Qingguo Xie
  • Patent number: 10611699
    Abstract: A method of determining the volume of organic material in a composting device includes rotating a mixing paddle in a composting bin that stores the organic material; monitoring the torque from a motor that rotates the mixing paddle as the mixing paddle rotates; and determining the height of the organic material in the composting bin based on the motor torque and the angular displacement of the mixing paddle. The resulting height can be used to determine the volume of the organic material.
    Type: Grant
    Filed: November 17, 2016
    Date of Patent: April 7, 2020
    Inventors: Alexander Joseph Halbleib, Gregory Samuel Lieto, Matthew MacLean
  • Patent number: 10590046
    Abstract: The disclosure relates to a composting device including a housing defining an interior with an access opening providing access to the interior, a composter bin located within the interior and in communication with the access opening, and a door mounted to the housing that includes a fascia.
    Type: Grant
    Filed: May 19, 2016
    Date of Patent: March 17, 2020
    Assignee: Whirlpool Corporation
    Inventors: Abhishek P. Buzruk, Christopher C. Wilcox