Abstract: A method for applying a cosmetic composition to skin is disclosed. The method can include applying a first composition to skin that includes at least about 50% by weight of a volatile hydrocarbon, a film former, a solvent comprising an ester group, and a combination of ultraviolet A (UVA) and ultraviolet B (UVB) sunscreen agents, wherein the UVA sunscreen agent comprises 4-tert-butyl-4?-methoxydibenzoylmethane, wherein the first composition has an SPF of at least about 15 and a PFA of at least about 5, and wherein the first composition dries within two minutes after topical application to skin, and subsequently applying the cosmetic composition onto the first composition.

Abstract: The present invention provides a medical device containing a cake composition comprising aripiprazole as an active ingredient and capable of suppressing agglomeration of aripiprazole in a suspension obtained by resuspending a freeze-dried substance; and a cake composition comprising aripiprazole as an active ingredient. The present invention relates to a medical device containing, in a storage container whose inner wall is treated with silicone, a freeze-dried cake composition comprising separately prepared aripiprazole as an active ingredient, wherein there is a space between the inner wall and the cake composition; and a cake composition comprising aripiprazole as an active ingredient and having a strength of 5 to 100 N.

Abstract: A transdermal therapeutic system containing rotigotine base in a self-adhesive layer structure. The system includes a backing layer, and a rotigotine-containing biphasic layer. The biphasic layer has an outer phase having a composition including 75% to 100% of a polymer or a polymer mixture, and an inner phase that forms dispersed deposits in the outer phase. The inner phase includes rotigotine base and a polymer mixture of at least two hydrophilic polymers. The hydrophilic polymers are selected from the group of polyvinylpyrrolidones having a K-Value of at least 80, polyvinylpyrrolidones having a K-Value of less than 80, copolymers of vinyl caprolactam, vinylacetate and ethylene glycol, copolymers of vinylpyrrolidone and vinylacetate, copolymers of ethylene and vinylacetate, polyethylene glycols, polypropylene glycols, acrylic polymers, and modified celluloses. The polymer mixture in the inner phase is present in an amount sufficient so that it forms a solid solution with the rotigotine base.

Abstract: Various embodiments disclosed relate to water-based nail-treatment compositions including a first film-forming copolymer that is a copolymer of a (C1-C5)alkyl ester of methacrylic acid, of a (C1-C5)alkyl ester of acrylic acid, or a combination thereof, and of methacrylic acid. The nail-treatment compositions also include a second film-forming copolymer that is a copolymer of isophorone diisocyanate, a poly((C2-C3)alkylene oxide), and 2,2-bis(methylol)propionic acid. Methods of using the nail-treatment compositions and cured products of the same are also provided. A cured product of the nail-treatment composition can be monolithically peelable from the nail.

Abstract: [Problem] To provide a decorating powder composition for decorating the surface of a solid cosmetic material, in particular, for obtaining a solid cosmetic material having a beautiful appearance which is decorated with a glossy powder, and a decorating method using the decorating powder composition. [Solution] Provided are a decorating powder composition including a glossy powder which has been surface-treated with a silane compound or a silazane compound, and a method for decorating a solid cosmetic material, the method including causing the decorating powder composition to adhere to a printing plate and then bringing the printing plate into contact with a surface of the solid cosmetic material to transfer the decorating powder composition to the surface of the solid cosmetic material and decorate the solid cosmetic material.

Abstract: The present technology generally relates to an encapsulation system for delivery of an active agent, the encapsulation system comprising a matrix of microcapsules, wherein a first portion of microcapsules in the matrix of microcapsules has an average diameter of from about 0.1 microns to about 10 microns; a second portion of the microcapsules has an average diameter of from about 10 microns to about 100 microns; and a third portion of the microcapsules has an average diameter of from about 100 microns to about 500 microns; and wherein the active agent is encapsulated in the microcapsules.

Abstract: Provided herein relates to methods and compositions for preparing a silk microsphere and the resulting silk microsphere. In some embodiments, the methods and compositions described herein are all aqueous, which can be used for encapsulating an active agent in a silk microsphere, while maintaining activity of the active agent during processing. In some embodiments, the resulting silk microsphere can be used for sustained delivery of an active agent encapsulated therein.

Abstract: The present invention provides aqueous formulations containing an anti-infection agent, a biocompatible polysaccharide, an osmotic pressure regulator, a pH regulator, and water, wherein a gel containing the therapeutic agent is formed in situ upon instillation of the formulations onto the skin and a body cavity of a subject. The formulations of this invention are useful for treating infectious diseases of skin or a body cavity (e.g., eye, nose, or vagina) of a subject.

Abstract: The present invention provides a skin care preparation for babies, comprising: pharma grade water; at least one stabilizer; at least one nutrient; at least one emulsifier; wherein said preparation further comprises Zinc gluconate & magnesium asparate & copper gluconate (“SEPITONIC™-M3”) and Dunaliella salina extract.

Abstract: A chemical-free, body cleansing cream formulation is provided comprising organic Aloe vera gel, coconut oil, sunflower oil, shea butter, witch hazel, one or more essential oils such as clary sage or distilled lime, and one or more pH-balancing agents such as apple cider vinegar or citric acid. The formulation is a natural alternative to soap which does not include chemicals such as sodium hydroxide. The cleansing cream has no soapsuds and produces no foam, and yet can still cleanse the most intimate areas of the body with very little to no risk of skin irritation. Alternatively, the cream or formulation can include Tribulus, witch hazel, horny goat weed (Epimedium), shea butter, ginseng, citric acid, coconut oil, almond oil, and flaxseed.

Abstract: The invention relates to a cosmetic composition comprising a blue dye powder containing an anthocyan, a metal ion and tannic acid and a cosmetic additive. The invention also relates to a process for making up keratin materials by applying the cosmetic composition to the keratin materials.

Abstract: The present invention relates to the use of citrus fruit pieces, obtained by controlled osmotic dehydration of said citrus fruit in a sugar syrup, for mechanically exfoliating dead cells from the epidermis of the skin of a person. Said citrus fruit pieces include the peel and/or epicarp of said citrus fruit and have a furocoumarin compound content of less than 50 ppm.

Abstract: A skin treatment composition is described comprising a cryopreserved blend of natural materials including at least two components selected from the group consisting of wheat grass juice, wheat grass pulp, shea butter, cocoa powder, rice flour, coffee, jojoba oil, hemp oil, castor oil, and sugarcane juice. The skincare treatment composition is applied with a specialty applicator that is frozen into the compound during processing. Methods of making, packaging and using the compositions also are disclosed.

Abstract: The present invention relates to a nanoemulsion comprising at least one aqueous component and a carrier, wherein the carrier comprises at least one lipophilic component, at least one surfactant and at least one alcohol. The present invention further relates to a composition comprising said nanoemulsion and an active agent. In particular, the composition is present as a gel and the active agent is 5-aminolevulinic acid, a derivative, precursor and/or metabolite thereof. The invention further relates to the preparation of said nanoemulsion and/or composition and to their use for the treatment of dermatological diseases, virus-associated diseases as well as diseases associated with cell proliferation, in particular, tumor diseases and/or psoriasis. The present invention is further directed to the use of said nanoemulsion in cosmetics.

Abstract: The present invention is directed to a flexible controlled release film for delivering a medicinal or cosmetic agent, e.g., through the skin of a subject, which delivery system comprises (a) a microembossed flexible film including microcells; (b) a liquid composition filled in the microcells wherein said liquid composition comprises the medicinal or cosmetic agent; and (c) a flexible sealing layer to enclose the liquid composition within the microcells.

Abstract: A sub-centimeter structure includes a first structural component, a second structural component arranged proximate the first structural component, and a joint connecting the first and second structural components. The joint includes a material that has a first phase that is substantially rigid to hold the first and second structural components in a substantially rigid configuration while the material is in the first phase. The material of the joint has a second phase such that the joint is at least partially fluid to allow the first and second structural components to move relative to each other while the material is in the second phase. The joint interacts with the first and second structural components while the material is in the second phase to cause the first and second structural components to move relative to each other. And, the first and second structural components include a polymer.

Abstract: The present invention relates to a pharmaceutical granulate composition comprising Palbociclib free base, having improved bioavailability.

Abstract: One larger [1] and one smaller tube [2], forming a functional unit with the smaller tube [2] positioned within the larger tube [1], both tubes are relocatable and demountable, both tubes with an aperture [3 and 4] at both ends, at least one aperture [5] being provided in the wall of the outer tube located at a distance of about between 1 mm and 10 cm from the tip [6], or several apertures positioned in a segment of 1-250 mm from the tip, wherein the diameter of the single aperture is between 70% and 120% of the inner diameter of the outer tube [1], or in case of several apertures, for each aperture 30-60% of the inner diameter of the outer tube, wherein the outer diameter of the inner tube is between 0.6 mm and 2.0 mm (F2 to F6), the outer diameter of the outer tube is between 1.3 mm and 3.6 mm (F4 to F11), and the distance between the outer wall of the inner tube and the inner wall of the outer tube is between 0.1 mm to 3.0 mm.

Abstract: A purpose of the present invention is to provide an oil-in-water emulsion cosmetic having a fresh feeling in use like that of a skin-care cosmetic such as a milky lotion, while also allowing titanium oxide or zinc oxide, which are ultraviolet scattering agents, to be stably blended into the oil phase, and also providing excellent sunscreen effects. The present invention relates to an oil-in-water emulsion cosmetic characterized by comprising (A) an ultraviolet scattering agent having a hydrophobic surface; (B) a water-soluble alkyl-substituted polysaccharide derivative; (C) a higher alcohol; and (D) a non-ionic surfactant. The emulsion cosmetic of the present invention preferably has a viscosity, measured by a B-type viscometer at 30° C., of 12,000 mPa·s or lower.

Abstract: In an embodiment, the present disclosure relates to a composition for treating or preventing a skin condition. In some embodiments, the composition includes zinc oxide with a concentration between about 5 and 30 wt/wt %, coconut oil with a concentration between about 0.1 and 5 wt/wt %, tea tree oil with a concentration between about 0.00025 and 0.1 wt/wt %, citronella oil with a concentration between about 0.00025 and 0.1 wt/wt %, and lemongrass oil with a concentration between about 0.01 and 1 wt/wt %. In a further embodiment, the present disclosure pertains to a composition for treating or preventing a skin condition including zinc oxide with a concentration of about 24 wt/wt %, coconut oil with a concentration of about 1 wt/wt %, tea tree oil with a concentration of about 0.001 wt/wt %, citronella oil with a concentration of about 0.001 wt/wt %, and lemongrass oil with a concentration of about 0.08 wt/wt %.