Patents Examined by David W Berke-Schlessel
  • Patent number: 11560544
    Abstract: The present invention concerns a process for isolating an archaeon of the order of commensal clade Methanomassiliicoccales, the use of a culture and/or isolation medium comprising a sterile extract of a bacterial culture of a bacterium of genus Eggerthella, for the isolation and/or culture of an archaeon of the order of commensal clade Methanomassiliicoccales, and a pure, isolated archaeon Methanomethylophilus alvus Mx-05. It also concerns a culture method of an archaeon of the order of commensal clade Methanomassiliicoccales.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: January 24, 2023
    Assignees: LESAFFRE ET COMPAGNIE, UNIVERSITÉ CLERMONT AUVERGNE, INSTITUT DE RECHERCHE POUR LE DÉVELOPPMENT
    Inventors: Wajdi Ben Hania, Jean-François Brugere, Marie-Laure Fardeau, Bernard Ollivier
  • Patent number: 11559554
    Abstract: A composition composed of xylooligosaccharide, arabinogalactan, inulin, Ganoderma lucidum beta glucan, insoluble yeast ? (1, 3/1, 6)-glucan, soluble oat ? (1,3/1, 4)-glucan, and insoluble dried Saccharomyces cerevisiae fermentate, with a Bacillus coagulans component, for use in improving or maintaining digestive health, weight and glucose balance and boosting immunity is provided.
    Type: Grant
    Filed: April 10, 2018
    Date of Patent: January 24, 2023
    Assignee: KIBOW BIOTECH INC.
    Inventor: Natarajan Ranganathan
  • Patent number: 11559483
    Abstract: Methods and compositions for delivering medicine and other substances to the brain and the body via the cribriform plate using foamable compositions are described. Methods and compositions for improving nasal hygiene and moisturizing the nasal cavity using foamable compositions are also described.
    Type: Grant
    Filed: July 8, 2016
    Date of Patent: January 24, 2023
    Inventor: Sanjay Gupta
  • Patent number: 11555157
    Abstract: A method of producing liquid fuel and/or chemicals from a carbonaceous material entails combusting a conditioned syngas in pulse combustion heat exchangers of a steam reformer to help convert carbonaceous material into first reactor product gas which includes carbon monoxide, hydrogen, carbon dioxide and other gases. A portion of the first reactor product gas is transferred to a hydrogen reformer into which additional conditioned syngas is added and a reaction carried out to produce an improved syngas. The improved syngas is then subject to one or more gas clean-up steps to form a new conditioned syngas. A portion of the new conditioned syngas is recycled to be used as the conditioned syngas in the pulse combustion heat exchangers and in the hydrocarbon reformer. A system for carrying out the method include, a steam reformer, a hydrocarbon reformer, first and second gas-cleanup systems, a synthesis system and an upgrading system.
    Type: Grant
    Filed: March 10, 2020
    Date of Patent: January 17, 2023
    Assignee: ThermoChem Recovery International, Inc.
    Inventors: Ravi Chandran, Dave G. Newport, Daniel A. Burciaga, Daniel Michael Leo, Justin Kevin Miller, Brian Christopher Attwood
  • Patent number: 11548802
    Abstract: A composition for remediation of soil and groundwater containing halogenated compounds. The remediation composition includes an elemental iron-based composition, which may include activated carbon capable of absorbing the halogenated compounds with numerous pores impregnated with elemental iron. The remediation composition further includes a first bioremediation material including a blend of one-to-many organisms capable of degrading the halogenated compounds. The remediation composition includes an organic compound or polymeric substance and a second bioremediation material including a blend of one-to-many organisms capable of degrading the organic compound or polymeric substance over time (e.g., 20 to 365 or more days to provide a time release substrate-creating material or platform) into smaller molecules or compounds used by the organisms in the first bioremediation material while degrading the halogenated compounds.
    Type: Grant
    Filed: November 18, 2019
    Date of Patent: January 10, 2023
    Assignee: Remediation Products, Inc.
    Inventor: Scott Noland
  • Patent number: 11549100
    Abstract: A method of producing a cell mass by three-dimensional culture of primary cancer cells having proliferative ability and properties of handleability, versatility, and high-throughput performance, in which a tumor tissue is used as a starting material, proliferation of cells such as fibroblasts other than cancer cells is inhibited, and the cell mass includes primary cancer cells as a main component. The object is achieved by providing a method of producing a cell mass by three-dimensional culture of primary cancer cells using a tumor tissue, including: a three-dimensional culture step of culturing cells obtained from the tumor tissue in a medium containing a 5% v/v or less extracellular matrix on a substantially low-adhesive cell culture substrate.
    Type: Grant
    Filed: March 15, 2018
    Date of Patent: January 10, 2023
    Assignee: LSI MEDIENCE CORPORATION
    Inventors: Hideaki Kakinuma, Yukiko Shimada, Hiroaki Inoue, Takashi Morikawa
  • Patent number: 11548785
    Abstract: The invention is directed to a control method for a process to convert bisulphide to elemental sulphur in an aqueous solution comprising sulphide-oxidising bacteria wherein the process is controlled by applying a potential between the anode electrode and the cathode electrode or between the anode electrode and the reference electrode of an electrochemical cell resulting in a current between the cathode electrode and the anode electrode, measuring a current as measured by an electrochemical cell and adapting the process in response to the measured current. The process to convert bisulphide may comprise the following steps: (a) contacting bisulphide with oxidised sulphide-oxidising bacteria in the aqueous solution and elemental sulphur, (b) oxidizing the reduced sulphide-oxidising bacteria, (c) using the oxidised sulphide-oxidising bacteria obtained in step (b) in step (a) and (d) isolating elemental sulphur from the aqueous solution obtained in step (a) and/or step (b).
    Type: Grant
    Filed: May 30, 2018
    Date of Patent: January 10, 2023
    Assignee: PAQELL B.V.
    Inventors: Johannes Bernardus Maria Klok, Annemiek Ter Heijne, Frederikus De Rink, Cees Jan Nico Buisman
  • Patent number: 11535880
    Abstract: Described herein are engineered organelles comprising multi-component proteins from different species incorporated into a membrane structure with interior and exterior aspects. In one embodiment the artificial organelle incorporates one or more protein complexes that absorb optical energy and catalyze electron transfer in biochemical reactions that can be used to reduce NAD+ to NADH or analogues thereof.
    Type: Grant
    Filed: January 7, 2021
    Date of Patent: December 27, 2022
    Assignee: ENSOVI, INC.
    Inventors: Kyle A. Minor, Carlo D. Montemagno, David W. Wendell
  • Patent number: 11523614
    Abstract: A water soluble granule (SG) of Bacillus velezensis, including 0.1-97 parts by weight of the stock powder of B. velezensis or/and its secondary metabolic active bacteriostatic substances, 1-5 parts by weight of a binder, 1-10 parts by weight of a disintegrant, 1-5 parts by weight of a dispersant, and other filler making up to 100 parts by weight. The soluble granule of B. velezensis has advantages of good storage resistance, easy use, strong activity and high safety.
    Type: Grant
    Filed: November 14, 2019
    Date of Patent: December 13, 2022
    Inventor: Zhijun Lu
  • Patent number: 11511017
    Abstract: The present disclosure describes methods of treating a ligament injury with ligament grafting.
    Type: Grant
    Filed: March 11, 2020
    Date of Patent: November 29, 2022
    Assignee: ARTHREX, INC.
    Inventors: David O. Shepard, Robert Harrison, Robert Benedict
  • Patent number: 11485948
    Abstract: The present invention relates to a process for depositing at least a culture of microorganisms to an elongated element, preferably a yarn, comprising the steps of: providing at least a first feeding device comprising at least a first outlet; supplying at least one elongated element to said at least first feeding device; feeding to said first outlet at least a first culture comprising at least one microorganism; dispensing said first culture from said at least first outlet; contacting at least part of said elongated element with said first culture of microorganisms, to provide at least a part of said elongated element with an amount of said first culture of microorganisms.
    Type: Grant
    Filed: June 10, 2019
    Date of Patent: November 1, 2022
    Assignee: Sanko Tekstil Isletmeleri San. Ve Tic. A.S.
    Inventors: Jitka Eryilmaz, Ece Senel, Seref Agzikara, Nejdiye Gunes, Fehim Caglar, Semih Kazanc, Ozgur Cobanoglu
  • Patent number: 11479746
    Abstract: The disclosure relates to methods, systems and compositions for use in the production of milk. More specifically, the disclosure is directed to systems, compositions and methods for in-vitro production of milk using an array of mammary organoids seeded on tertiary-branched, resilient duct scaffolding.
    Type: Grant
    Filed: December 6, 2021
    Date of Patent: October 25, 2022
    Assignee: Biomilk Ltd.
    Inventor: Sharon Fima
  • Patent number: 11473053
    Abstract: A hydrogel capsule comprising a stem cell core that has been induced to differentiate into a hematopoietic lineage cell, and methods for the production of hematopoietic lineage cells from stem cells encapsulated in a hydrogel.
    Type: Grant
    Filed: October 31, 2019
    Date of Patent: October 18, 2022
    Assignee: PLASTICELL LTD.
    Inventors: Marina Tarunina, Cedric Humbert, Shahzad Ali, Yen Choo, Aaron Tsu Tshen Chuang, Dennis Saw
  • Patent number: 11453852
    Abstract: The disclosure relates to methods, systems and compositions for use in the production of milk. More specifically, the disclosure is directed to systems, compositions and methods for in-vitro production of milk using an array of mammary organoids seeded on tertiary-branched, resilient duct scaffolding.
    Type: Grant
    Filed: December 6, 2021
    Date of Patent: September 27, 2022
    Assignee: Biomilk Ltd.
    Inventor: Sharon Fima
  • Patent number: 11448644
    Abstract: The invention relates generally to compositions and methods for the detection of zinc. In particular, compositions and methods are provided to detect changes in cellular zinc concentration and to correlate them to cellular phenomena.
    Type: Grant
    Filed: July 16, 2019
    Date of Patent: September 20, 2022
    Assignee: Northwestern University
    Inventors: Teresa K. Woodruff, Thomas V. O'Halloran, Alison M. Kim, Emily Que, Betty Kong, Miranda Bernhardt
  • Patent number: 11447738
    Abstract: The disclosure provides compositions comprising a disaccharide, a nutrient, and a buffer, which may be used for the preservation of bacteria, such as during lyophilization and/or extended storage. Provided herein are methods for preserving bacteria, involving adding bacteria to the compositions and subjecting the compositions to a lyophilization cycle. Also provided herein are methods for generating compositions that may be used, for example for the preservation of bacteria.
    Type: Grant
    Filed: October 27, 2017
    Date of Patent: September 20, 2022
    Assignee: Vedanta Biosciences, Inc.
    Inventors: Daniel E. Couto, Shilpa Reddy, Jil Ulrich, Scott Michonski
  • Patent number: 11446337
    Abstract: This document discusses, among other things, receiving a plurality of donor fecal samples from a plurality of donors and storing and indexing each respective donor fecal samples using at least one characteristic of the respective donor fecal sample. In an example, the donor fecal sample can be screened and processed for subsequent use in fecal bacteriotherapy to displace pathogenic or undesired organisms in the digestive track of a patient with healthy or desirable gut microbiota.
    Type: Grant
    Filed: April 27, 2018
    Date of Patent: September 20, 2022
    Assignee: REBIOTIX, INC.
    Inventor: Edwin J. Hlavka
  • Patent number: 11441111
    Abstract: The disclosure relates to methods, systems and compositions for use in the production of milk. More specifically, the disclosure is directed to systems, compositions and methods for in-vitro production of milk using an array of mammary organoids seeded on tertiary-branched, resilient duct scaffolding.
    Type: Grant
    Filed: December 6, 2021
    Date of Patent: September 13, 2022
    Assignee: Biomilk Ltd.
    Inventor: Sharon Fima
  • Patent number: 11433108
    Abstract: Therapeutic methods for administering gut microbiota and oncolytic viruses to a subject are provided. The gut microbiota serve to pre-condition, the subject's immune system to antitumor responses and augments anticancer activity of the oncolytic vims. Combinations of the gut. microbiota and viruses and uses thereof for treating and preventing cancer are provided. The present disclosure also provides methods for building elite responder selection platforms through hierarchical clustering analysis of genomic profiles for human gut microbiome.
    Type: Grant
    Filed: March 28, 2017
    Date of Patent: September 6, 2022
    Assignee: SUZHOU PRAJNA BIOTECH CO., LTD.
    Inventors: Minjie Hu, Yu Li, Xiaoling Liu, Rebecca Hu
  • Patent number: 11434466
    Abstract: The present invention provides a process of cultivating microalgae and a joint method of same jointed with denitration. During the microalgae cultivation, EM bacteria is added into the microalgae suspension. In the nutrient stream for cultivating microalgae, at least one of the nitrogen source, phosphorus source and carbon source is provided in the form of a nutrient salt. During the cultivation, the pH of the microalgae suspension is adjusted with nitric acid and/or nitrous acid. The joint method includes (1) a step of cultivating microalgae; (2) a separation step of separating a microalgae suspension obtained from step (1) into a wet microalgae (microalgae biomass) and a residual cultivation solution; and (3) a NOx absorbing/immobilizing step of denitrating an industrial waste gas with the residual cultivation solution obtained from step (2). The nutrient stream absorbed with NOx obtained from step (3) is used to provide nitrogen source to the microalgae cultivation of step (1).
    Type: Grant
    Filed: March 17, 2015
    Date of Patent: September 6, 2022
    Assignees: CHINA PETROLEUM & CHEMICAL CORPORATION, RESEARCH INSTITUTE OF PETROLEUM PROCESSING, SINOPEC
    Inventors: Junfeng Rong, Xuhua Zhou, Lin Cheng, Junying Zhu, Xugeng Huang, Baoning Zong