Patents Examined by Deborah Carr
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Patent number: 6087305Abstract: A mixture consisting essentially of:a) one or more dicarboxylic acid esters of the formula IROOC--A--COOR (I)in which the radicals R independently of one another are alkyl groups having 1 to 20 carbon atoms and A is alkylene having 1 to 20 carbon atoms, alkenylene or alkynylene each having 2 to 20 carbon atoms, cycloalkylidene or cycloalkenylidene each having 5 or 6 carbon atoms or phenyleneandb) the product (II) of the reaction of a triglyceride based on carboxylic acids having 2 to 30 carbon atoms and ethylene oxide and/or propylene oxide in the presence of a base,which is useful for the production of crop protection compositions, for herbicidal crop protection compositions, and for controlling undesired plant growth, and spray mixtures comprising the compositions.Type: GrantFiled: February 6, 1997Date of Patent: July 11, 2000Assignee: BASF AktiengesellschaftInventors: Reiner Kober, Karl-Heinrich Schneider, Wilhelm Rademacher, Reinhold Stadler, Bernd Burkhart, Guenter Oetter, Matthias Gerber, Wessel Nuyken, Oskar Schmidt, Hans Ziegler, Elmar Kibler, Thomas Kroehl
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Patent number: 6063947Abstract: An endogenous oil extracted from Brassica seeds is disclosed that contains, after crushing and extraction, greater than 86% oleic acid and less than 2.5% .alpha.-linolenic acid. The oil also contains less than 7% linoleic acid. The Brassica seeds are produced by plants that contain seed-specific inhibition of microsomal oleate desaturase and microsomal linoleate desaturase gene expression. Such inhibition can be created by cosuppression or antisense technology. Such an oil has a very high oxidative stability in the absence of added antioxidants.Type: GrantFiled: August 8, 1997Date of Patent: May 16, 2000Assignee: Cargill, IncorporatedInventors: Lorin R. DeBonte, William D. Hitz
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Patent number: 6060612Abstract: Disclosed herein is a ceramide-like compound having properties of the natural ceramides, and a method for producing the same, and a cosmetic composition containing the same as a active ingredient.Type: GrantFiled: December 10, 1997Date of Patent: May 9, 2000Assignee: Pacific CorporationInventors: Jong Eon Hong, Myeung Su Ku, Bo Sub Lee, Young Hun Byon, Duk Hee Kim, Sang Rhin Lee, Ok Sob Lee, Hae Kwang Lee, Jong Ho Park, Ki Wha Lee, Ki Tack Nam, Jong Il Kim, Hyun Jun Kim, Hey Jin Jung
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Patent number: 6054599Abstract: Novel phytosphingosine-based analogs of ceramide I, methods for the preparation of these novel compounds, cosmetic and pharmaceutical compositions containing such compounds, and methods for the use thereof are described.Type: GrantFiled: May 5, 1998Date of Patent: April 25, 2000Assignee: DSM N.V.Inventors: Pieter Gijsbert Weber, Johannes Wilhelmus Jacobus Lambers, Hein Simon Koger, Jan Verweij
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Patent number: 6037338Abstract: The present invention relates to a biodegradable plastic made from a combination of at least one synthetic plastic polymer, at least one natural polymer and a natural polymer attacking agent and articles made therefrom.The present invention further relates to a method of eliminating hydrocarbon contaminating a region subjected to extreme temperatures by contacting the region with hydrocarbon-degrading microorganisms and adjusting the temperature of the region for optimum growth.The present invention also relates to a method of treating aspirin-treatable conditions comprising administering to a patient in need of such treatment a compound of Formula I ##STR1## In addition, the present invention relates to a method of protecting a philatelic item bearing a mark identifying an expert or owner of the item and possibly an additional distinguishable mark specific to the philatelic item from alteration.Type: GrantFiled: November 14, 1997Date of Patent: March 14, 2000Inventor: Alvin Guttag
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Patent number: 6034257Abstract: In a process for preparing an alkoxylated amide of the formula (I)R.sup.1 --CO--NR.sup.2 --CHR.sup.3 --CHR.sup.4 --O--(CHR.sup.5 --CHR.sup.6 --O).sub.n --H (I)(1) glycerides of the fatty acids, specified later on, of the formula (II):R.sup.1 --COOH (II)are reached with amines of the formula (III)HNR.sup.2 R.sup.7 (III)to give amides of the formula (IV)R.sup.1 --CO--NR.sup.2 --R.sup.7 (IV)and glycerol,(2) then the glycerol which has been formed is separated off by adding of aqueous acid solution to the reaction mixture until it has a pH in the range 1-7, in order to bring about phase separation into a glycerol-containing aqueous phase and an organic phase containing amides of the formula (IV), and separating off the aqueous phase, and(3) subsequently the amide of the formula (IV) is reacted with ethylene oxide and/or propylene oxide and/or butylene oxide to give alkoxylated amides of the formula (I).Type: GrantFiled: June 3, 1999Date of Patent: March 7, 2000Assignee: BASF AktiengesellschaftInventors: Alfred Oftring, Gunter Oetter, Richard Baur, Oliver Borzyk, Bernd Burkhart, Christian Ott, Martin aus dem Kahmen
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Patent number: 6028229Abstract: A process for the production of end-capped nonionic surfactants corresponding to formula (I): ##STR1## in which R.sup.1 is an alkyl or alkenyl group containing 6 to 22 carbon atoms, n1 and n2 independently of one another represent 0 or a number from 1 to 10, m represents a number from 1 to 20 and R.sup.2 represents methyl or ethyl, by(a) etherifying a fatty alcohol polyglycol ether corresponding to formula (II): ##STR2## in which R.sup.1, n1, n2 and m are as defined above, with a dialkyl sulfate in the presence of a solid substantially water-free base and an alkali metal or alkaline earth metal hydride,(b) adding water to the crude ethers in such a quantity that phase separation occurs, and(c) removing the organic phase.Type: GrantFiled: August 11, 1997Date of Patent: February 22, 2000Assignee: Henkel Kommanditgesellschaft auf AktienInventors: Joaquim Bigorra Llosas, Nuria Bonastre, Rafael Pi Subirana, Antonio Trius Oliva
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Patent number: 6025511Abstract: A method of inhibiting parasitic activity is disclosed in which the biosynthesis, structure and/or function of the glycosyl phosphatidylinositol (GPI) anchor of said parasite may be affected by incorporating into said GPI anchor selected analogs of myristic acid containing various heteroatoms, substituents and unsaturated bonds, including ester-containing analogs, ketocarbonyl-containing analogs, sulfur-containing analogs, double bond- and triple bond-containing analogs, aromatic moiety-containing analogs, nitrated analogs and halogenated analogs.Type: GrantFiled: March 31, 1998Date of Patent: February 15, 2000Assignees: Washington University, Johns Hopkins UniversityInventors: Jeffrey I. Gordon, George W. Gokel, Paul T. Englund
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Patent number: 6025509Abstract: Soybeans (ie., Glycine max L. Merr.) possessing a novel genetic determinant for the enhanced production of palmitic acid in the endogenously formed vegetable oil of the seeds are provided. Such genetic determinant is the homogeneous recessive fap5fap5 gene pair that has been found to be capable of formation through mutagenesis. Once formed, such genetic determinant can be readily transferred to other soybean lines and cultivars where it is similarly expressed on a reliable basis under conventional field growing conditions. In a preferred embodiment when a soybean plant possesses the combined presence of the homogeneous recessive genes (1) fap2-bfap2-b, (2) fap4fap4, as well as (3) fap5fap5 for enhanced palmitic acid formation in the seeds, it has been found that an unusually high expression for palmitic acid production in the resulting vegetable oil of the seeds is provided that is in excess of 30 up to approximately 37 percent by weight based upon the total fatty acid content.Type: GrantFiled: March 23, 1998Date of Patent: February 15, 2000Assignee: Iowa State University Research Foundation, Inc.Inventors: Walter R. Fehr, Earl G. Hammond
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Patent number: 6020317Abstract: The object of the invention is to provide a lipid device functionally equivalent to the so-called cationic liposome and of lesser toxicity and a lipid or the like as a component of the device.The compound of the invention includes but is not limited to 3-O-(4-dimethylaminobutanoyl)-1,2-O-dioleylglycerol, 3-O-(2-dimethylaminoethyl)carbamoyl-1,2-O-dioleylglycerol, 3-O-(2-diethylaminoethyl) carbamoyl-1,2-O-dioleylglycerol and 2-O-(2-diethylaminoethyl) carbamoyl-1,3-O-dioleoylglycerol. The device of the invention comprises such a lipid and a phospholipid.By administering a double-stranded RNA, for instance, together with the device of the invention, the double-stranded RNA can be safely delivered to the site of action.Type: GrantFiled: October 23, 1995Date of Patent: February 1, 2000Assignee: Nippon Shinyaku Co. Ltd.Inventors: Yano Junichi, Tadaaki Ohgi
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Patent number: 6020509Abstract: A process for producing a surfactant composition by partially saponifying an alkoxylated triglyceride having the formula: ##STR1## with an alkali metal hydroxide such as sodium hydroxide and recovering a surfactant composition comprising soap and moisturizing agents comprised of alkoxylated monoglycerides and unreacted alkoxylated triglycerides.Type: GrantFiled: December 22, 1998Date of Patent: February 1, 2000Assignee: Condea Vista CompanyInventors: Upali Weerasooriya, Paul A. Filler, Janet L. Watson
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Patent number: 5846955Abstract: This invention relates to a method for improving the efficiency of a drug containing a free carboxy group, the improvement comprising esterifying said carboxy group to the hydroxy group of the glycerol portion of a glycerolphospholipid ester having the formula: ##STR1## or pharmaceutically acceptable salts thereof wherein one of R.sub.1 and R.sub.2 is hydrogen and the other is hydrogen, a hydrocarbyl fatty acid acyl group having 4-26 carbon atoms or a hydrocarbyl heteroatom fatty acid acyl group having 3-25 carbon atoms, or ##STR2## and R is a naturally occurring polar head group characteristic of a glycerophospholipid isolated from endogenous sources;R.sub.3 is hydrogen or lower alkyl andR.sub.Type: GrantFiled: June 6, 1995Date of Patent: December 8, 1998Assignee: Research Corporation Technologies, Inc.Inventors: Charles Pidgeon, Robert J. Markovich
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Patent number: 5808119Abstract: Process for esterifying a polyphenolic oligomer extract of plant origin by the action of an acid chloride, the compositions obtained by this process and their use in human therapy or in cosmetics are described. The extract is placed in a liquid medium which is not a solvent for the extract but which is a solvent for the ester(s) to be obtained, so as to obtain a suspension. At least one aliphatic tertiary amine of low boiling point is added to the suspension in the presence of a catalytic amount of at least one organic base other than pyridine. At least one fatty acid chloride is introduced into this mixture, the reaction mixture being stirred at a temperature below 40.degree. C. and then concentrated by evaporation in order to obtain an esterified extract.Type: GrantFiled: August 23, 1995Date of Patent: September 15, 1998Assignee: BerkemInventor: Jean Nkiliza
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Patent number: 5523433Abstract: Disclosed is a process for making di(acyloxyalkyl) di(alkyl) ammonium compounds useful as fabric softeners. The corresponding di(hydroxyalkyl) tertiary amine is diesterified under conditions determined to minimize the formation of monoester side product and then the diester is quaternized under conditions effective to minimize degradation of the quaternized diester.Type: GrantFiled: September 29, 1994Date of Patent: June 4, 1996Assignee: Witco CorporationInventors: Christopher J. Toney, Phillip S. Welte, Robert K. Lagerman
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Patent number: 5380894Abstract: A process for the production of hydroxy fatty acids and novel estolide compounds, each of which may be used as lubricants, greases, plasticizers and printing inks, as well as in cosmetics. The estolides are of the formula (I): ##STR1## wherein R.sub.1 is selected from C.sub.6 -C.sub.16 hydrocarbons which may be saturated or unsaturated, and branched or straight chain, and optionally substituted, such as with one or more hydroxy groups; R.sub.2 is independently selected from C.sub.2 -C.sub.17 hydrocarbons which may be saturated or unsaturated, and branched or straight chain, and optionally substituted, such as with one or more hydroxy groups; A is selected from C.sub.3 -C.sub.14 hydrocarbons which may be saturated or unsaturated, and branched or straight chain, and optionally substituted; n is greater than or equal to 1; y is an integer from 3-13; x is 1 or 2; and . . . designates a single or double carbon/carbon bond.Type: GrantFiled: March 1, 1991Date of Patent: January 10, 1995Assignee: The United States of America as represented by the Secretary of AgricultureInventors: Douglas A. Burg, Robert Kleiman, Selim M. Erhan
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Patent number: 5175322Abstract: A continuous process for preparing a metallic soap by a double decomposition process is disclosed, in which an aqueous solution of an alkali soap and an inorganic metal salt are separately fed directly on the surface of the rotating impeller of a mixer to instantaneously mix them together and the resulting metallic soap aqueous slurry is discharged out from the mixer without delay. Metallic soaps free from contamination with unreacted starting materials or by-products can be continuously obtained using small-sized reactor vessels with a reduced energy.Type: GrantFiled: November 27, 1989Date of Patent: December 29, 1992Assignee: Nippon Oil and Fats Co., Ltd.Inventors: Fumihiko Yoshizawa, Fumio Kikuchi, Seiichi Kojima, Kenichi Yuasa
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Patent number: 5153341Abstract: An improved process for preparing alkanoyloxyacetyloxybenzenesulfonate salts in which phenyl esters of alkanoyloxyacetic acids (alkanoyloxyacetyloxybenzenes) are sulfonated to yield novel alkanoyloxyacetyloxybenzenesulfonic acids which, on neutralization, yield the corresponding alkanoyloxyacetyloxybenzenesulfonate salts.Type: GrantFiled: March 25, 1991Date of Patent: October 6, 1992Assignee: E. I. Du Pont de Nemours and CompanyInventors: Bijan Amini, Donald J. Dumas, George C. Sonnichsen
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Patent number: 5102581Abstract: Process for the preparation of: ##STR1## by oxidative decarboxylation of an allyl .beta.-ketoester: ##STR2## in an organic solvent, in the presence of a palladium-based catalyst. The organic solvent selected from an amide, a nitrile, or a dinitrile.Type: GrantFiled: June 21, 1990Date of Patent: April 7, 1992Assignee: Rhone-Poulenc SanteInventors: Claude Mercier, Gerard Mignani
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Patent number: 4966897Abstract: This invention is directed to 4-substituted 17.beta.-(cyclopropyloxy)androst-5-en-3.beta.-ols and related compounds and also to a method for using such compounds in the treatment of androgen-dependent disorders. The ethers are prepared by using the Simmons-Smith reaction and an appropriate vinyl ether.Type: GrantFiled: August 15, 1989Date of Patent: October 30, 1990Assignee: Merrell Dow Pharmaceuticals Inc.Inventors: Michael R. Angelastro, Thomas R. Blohm