Patents Examined by Dennis White
  • Patent number: 11986299
    Abstract: Methods and systems are provided for point-of-care nucleic acid amplification and detection. One embodiment of the point-of-care molecular diagnostic system includes a cartridge and an instrument. The cartridge can accept a biological sample, such as a urine or blood sample. The cartridge, which can comprise one or more of a loading module, lysis module, purification module and amplification module, is inserted into the instrument which acts upon the cartridge to facilitate various sample processing steps that occur in order to perform a molecular diagnostic test.
    Type: Grant
    Filed: November 2, 2020
    Date of Patent: May 21, 2024
    Assignee: Talis Biomedical Corporation
    Inventors: Sayeed Andeshmand, Thomas H. Cauley, III, John Dixon, David Glade, Hédia Maamar, Michael John McAdams, Dzam-Si Jesse Ng, David Alexander Rolfe
  • Patent number: 11982636
    Abstract: Provided are a method and a device for acquiring a temperature and a computer-readable storage medium. The method for acquiring a temperature includes: building a temperature acquisition model, wherein the temperature acquisition model is configured to acquire, based on an operating parameter of the radioactive substance treatment system input to the temperature acquisition model, a temperature of different parts of the radioactive reactant in the radioactive substance treatment system under a condition of the parameter; inputting a current operating parameter of the radioactive substance treatment system into the temperature acquisition model during the treatment for the radioactive substance; and acquiring a current temperature of different parts of the radioactive reactant in the radioactive substance treatment system output by the temperature acquisition model.
    Type: Grant
    Filed: June 17, 2022
    Date of Patent: May 14, 2024
    Assignee: China Institute of Atomic Energy
    Inventors: Shengdong Zhang, Dongdong Zhu, Yusong Li, Dongsheng Qie, Liang Xian, Runci Wang, Lijun Liu
  • Patent number: 11977085
    Abstract: The present invention relates to devices and methods for detecting date rape drugs (DRDs) in beverages during social events. The device includes a cellphone, and further includes one or more protective covers, screen cover, stylus, or other add-ons, either individually or in combination. The device incorporates a user-friendly DRD detection system physically attached or integrated with the cellphone or any one of its accessories, ensuring uninterrupted use of the device's primary functions, wherein this physical attachment and/or integration minimizes the likelihood of users forgetting the device elsewhere and/or removing the DRD detection system, thus ensuring its immediate availability when needed. The DRD detection system's operation does not significantly impact the regular use of the cellphone or its accessories, maintaining convenience and safety in social settings.
    Type: Grant
    Filed: September 6, 2023
    Date of Patent: May 7, 2024
    Inventor: Elan Ehrlich
  • Patent number: 11974732
    Abstract: A system for urine analysis and personal health monitoring includes a testing box, including a testing chamber, a camera aperture, a visual check aperture, and a test slot, an interchangeable color pattern chart, including a bar code, a base color calibration strip, a test result area, and a test lookup area; a diagnostic analysis server, and a diagnostic analysis device, including a processor, a diagnostic manager, a camera manager, an image analyzer, a camera calibrator, and a camera; such that the diagnostic analysis device captures an original image of the testing chamber interior with a test strip inserted, and analyzes a diagnostic portion of the original image and calculates a test result. Also disclosed is a method for diagnostic analysis, including installing interchangeable color pattern chart, depositing sample, inserting test strip, capturing image, performing color calibration, reading bar code, extracting test strip image, performing color conversion, and calculating test result.
    Type: Grant
    Filed: October 14, 2020
    Date of Patent: May 7, 2024
    Inventors: Chun S. Li, Richard Y. Li
  • Patent number: 11964272
    Abstract: Disclosed are a detection chip, a preparation method and use method thereof, and a detection device. The detection chip comprises a substrate and a reservoir chamber. The reservoir chamber is configured to contain a liquid and comprises a support frame, and a first seal layer and a second seal layer for sealing the support frame. The support frame comprises a support frame body and a cavity formed in the middle of the support frame body. The second seal layer is configured to be concaved into the cavity. The substrate comprises a piercing structure.
    Type: Grant
    Filed: June 15, 2021
    Date of Patent: April 23, 2024
    Assignee: BOE Technology Group Co., Ltd.
    Inventors: Chenyu Wang, Yufan Zhang, Jing Zhao
  • Patent number: 11958048
    Abstract: A plasmon resonance system, instrument, cartridge, and methods for analysis of analytes is disclosed. A PR system is provided that may include a DMF-LSPR cartridge that may support both digital microfluidic (DMF) capability and localized surface plasmon resonance (LSPR) capability for analysis of analytes. In some examples, the DMF portion of the DMF-LSPR cartridge may include an electrode arrangement for performing droplet operations, whereas the LSPR portion of the DMF-LSPR cartridge may include an LSPR sensor. In other examples, the LSPR portion of the DMF-LSPR cartridge may include an in-line reference channel, wherein the in-line reference channel may be a fluid channel including at least one functionalized LSPR sensor (or sample spot) and at least one non-functionalized LSPR sensor (or reference spot). Additionally, methods of using the PR system for analysis of analytes are provided.
    Type: Grant
    Filed: February 27, 2022
    Date of Patent: April 16, 2024
    Assignee: National Research Council of Canada
    Inventors: Ryan Denomme, Lidija Malic, Daniel Brassard, Keith Morton, Teodor Veres
  • Patent number: 11946843
    Abstract: Sample filtration devices are provided. The devices can comprise a filter membrane positioned between an input and output substrate and joined using an adhesive layer. The filter assembly can be used with various sample collection and dispensing devices, such as a flexible container, a bulb pipette, a micropipette, etc. Applying pressure to the filter assembly, e.g., using a flexible container, a bulb pipette or a micropipette can force the fluid through the filter membrane and onto a test strip or cartridge.
    Type: Grant
    Filed: June 26, 2018
    Date of Patent: April 2, 2024
    Assignee: SPLITRX LLC
    Inventor: Estevan Mendoza
  • Patent number: 11927560
    Abstract: Described are methods and devices that can accelerate the process and quantify the parameters for bio/chemical material samples. In some embodiments, a QMAX (Q: quantification; M: magnifying; A: adding reagents; X: acceleration) device having two or more electrodes capable of accelerating the electrical measurement process of the samples. In addition, the electrical measurement technology of the QMAX device enables for extraction, separation, and purification of sample components, such as but not limited to nucleic acids. In some embodiments, the QMAX device includes a plate for hosting a small sensing chip to facilitate a bio/chemical sensing of the sensing chip.
    Type: Grant
    Filed: February 8, 2018
    Date of Patent: March 12, 2024
    Assignee: Essenlix Corporation
    Inventors: Stephen Y. Chou, Wei Ding, Yufan Zhang
  • Patent number: 11918358
    Abstract: A test strip eject mechanism for a fluid testing device comprising an actuation button and a lever having a distal end movably engaged with the button, the lever configured to rotate about a fulcrum, wherein the lever has a proximal end movably engaged with a sled which slides to transport the test strip, the device configured such that a user's insertion of a test strip onto the sled and in an insertion direction into the device causes the sled to contact the lever arm and the lever arm to contact and move the actuation button in an outward direction of the medical device and into a position where the actuation button can be actuated by the user.
    Type: Grant
    Filed: September 24, 2020
    Date of Patent: March 5, 2024
    Assignee: Roche Diabetes Care, Inc.
    Inventors: Michel Alain Jean Marie Cadio, Ahmet Konya
  • Patent number: 11890620
    Abstract: Miniaturized DNA microarrays are described to be used in conjunction with microfluidic channels or microcentrifuge tubes and microcentrifuge filters to reduce sample size, incubation time and to increase overall binding efficiency.
    Type: Grant
    Filed: October 12, 2018
    Date of Patent: February 6, 2024
    Assignee: The Charles Stark Draper Laboratory, Inc.
    Inventors: Kirsty A. McFarland, Charles A. Lissandrello, Andrew P. Magyar, Erin Rosenberger
  • Patent number: 11892393
    Abstract: A system and method for treating water containing at least one contaminant. The system and method include a water treatment module such as a reverse osmosis unit. An electrochemical contaminant detection system is positioned in the waste water stream of the water treatment module. The contaminant detection system includes a contaminant sensor and a water quality sensor module. The contaminant sensor measures the concentration of the contaminant in the waste water stream and the water quality sensor module measures one or more water quality parameters of the waste water stream. A processor uses an algorithm to determine the concentration of the contaminant in the feed water based on the measurements of the contaminant sensor and water quality sensor module.
    Type: Grant
    Filed: October 26, 2020
    Date of Patent: February 6, 2024
    Assignee: A.O. Smith Corporation
    Inventor: Gusphyl Antonio Justin
  • Patent number: 11883012
    Abstract: Various systems, devices, components, and methods are disclosed for measuring the concentration of an analyte, such as acetone, in a breath sample. The disclosed devices include a breath sample analysis device having a mouthpiece configured to facilitate engagement with a user's mouth to receive a breath sample. The disclosed devices also include a breath sample capture cartridge containing an interactant that extracts the analyte from a breath sample passed through the cartridge. Also disclosed are devices for routing the breath sample through the cartridge during exhalation, and for analyzing a reaction in the cartridge to measure a concentration of the analyte.
    Type: Grant
    Filed: November 18, 2022
    Date of Patent: January 30, 2024
    Assignee: Invoy Holdings Inc.
    Inventors: Zachary B. Smith, Marcus Goudie, Lubna M. Ahmad
  • Patent number: 11885952
    Abstract: A method of assaying an analyte in a sample is disclosed. The method includes having a sample holder with a sample contact area for contacting a sample with an analyte, having a plurality of calibration structures on the sample contact area of the sample holder, imaging a part of the sample contact area that has the calibration structures, and using an algorithm that includes an image, calibration structures in the image, and artificial intelligence and/or machine learning to identify the analyte and/or determine the analyte concentration.
    Type: Grant
    Filed: July 30, 2019
    Date of Patent: January 30, 2024
    Assignee: Essenlix Corporation
    Inventors: Stephen Y. Chou, Wei Ding, Ji Qi, Yuecheng Zhang, Wu Chou, Mingquan Wu, Xing Li, Jun Tian
  • Patent number: 11879330
    Abstract: Embodiments of a device, system and method are disclosed herein. In one embodiment, a device comprises a sample cell configured to interact a fluid sample with an ion selective substrate to modify an optical characteristic of the ion selective substrate according to an ion concentration of the fluid sample, wherein the sample cell is also configured to optically interact an illumination light with the ion selective substrate to generate a sample light; an optical element configured to interact with the sample light to provide a modified light that has a property of the fluid sample; and a detector that receives the modified light and provides an electrical signal proportional to the property of the fluid sample indicated by the modified light; and wherein the ion selective substrate comprises a membrane, the membrane configured to change an optical property in a selected wavelength range, according to the property of the fluid sample.
    Type: Grant
    Filed: June 28, 2022
    Date of Patent: January 23, 2024
    Assignee: Halliburton Energy Services, Inc.
    Inventors: Michel Joseph LeBlanc, Bin Dai, James M. Price
  • Patent number: 11874269
    Abstract: A testing pad comprising a water-resistant base layer, a water-transmissive top layer coupled with said base layer, an hydrophilic intermediate layer contained between said top layer and said base layer, and a color-changing chemical reagent contained between said top layer and said base layer adapted an configured to allow an animal or person to urinate on the testing pad and the chemical reagent to present testing results related to the presence, absence and/or concentration of substances within the urine.
    Type: Grant
    Filed: June 8, 2020
    Date of Patent: January 16, 2024
    Inventors: Bonnie Goodman, Jeff Goodman
  • Patent number: 11860129
    Abstract: Devices that include a low sensitivity bulk acoustic wave (BAW) resonator sensor including a surface to which a low recognition component is immobilized, the low recognition component being configured to selectively bind the analyte, an analyte molecule to which a tag is linked, or a tag, or any one of these molecules to which an amplification element-linked second recognition component is bound; a high sensitivity BAW resonator sensor including a surface to which a high recognition component is immobilized, the high recognition component being configured to selectively bind the analyte, an analyte molecule to which a tag is linked, or a tag, or any one of these molecules to which an amplification element-linked second recognition component is bound; one or more containers housing an amplification molecule, the amplification element-linked second recognition component, and optionally one or both of the tag and the analyte molecule.
    Type: Grant
    Filed: July 6, 2022
    Date of Patent: January 2, 2024
    Assignee: Zomedica Biotechnologies LLC
    Inventors: James Russell Webster, Ian Robert Harmon
  • Patent number: 11837339
    Abstract: A portable data-management system based on an analyte testing device which communicates wirelessly with a mobile device. The mobile device runs an application to manage and analyze data obtained by the analyte testing device. The mobile device may assist the user in displaying testing data, identifying patterns to assist healthy behavior or issue warnings based on the collected data. The mobile device may be connected to a network to store user health data for use by other parties.
    Type: Grant
    Filed: June 22, 2020
    Date of Patent: December 5, 2023
    Assignee: Ascensia Diabetes Care Holdings AG
    Inventors: Jun Chen, Harris Lieber, Erik Nelson, Jeffery S. Reynolds, Kevin Curran, Aseem Mehta, Dawn Rountree
  • Patent number: 11835486
    Abstract: A test kit that is configured for bioanalysis, such as an immunoassay, is provided. The test kit includes at least one measuring sensor for quantitative detection of a substance, and at least one reference sensor that is already supplied with the substance in a defined manner. In a method for analyzing a test kit, the at least one measuring sensor is read, and a measurement value for a concentration, a substance quantity, or a mass is obtained. A read value of the at least one measuring sensor is scaled using read values of the at least one reference sensor, or a measured value that corresponds to the read value is obtained using a compensation curve that puts the read values of the at least one reference sensor into relationship with the defined supply of the substance to the at least one reference sensor.
    Type: Grant
    Filed: September 28, 2022
    Date of Patent: December 5, 2023
    Assignee: BioMensio Ltd.
    Inventors: Evamaria Stütz, Stephan Buchholz, Matthias Schreiter, Alexander Michael Gigler
  • Patent number: 11828756
    Abstract: Disclosed herein is a lateral flow test arrangement suitable for detection of an analyte in saliva. The arrangement can comprise a carrier and a sequence of different polymeric pads arranged on said carrier, wherein said sequence of polymeric pads comprises in flow direction.
    Type: Grant
    Filed: October 29, 2020
    Date of Patent: November 28, 2023
    Assignee: Feral GmbH
    Inventors: Gianluca Adornetto, Fabio La Manna, Eirini Rapti
  • Patent number: 11813611
    Abstract: A refrigerator, comprising: a refrigerator body internally defining a storage space for storing articles, a door connected to the refrigerator body and used for opening and/or closing the storage space, and a microfluidic detection system which is provided on the door and comprises: a microfluidic biochip having a sample inlet, a communication port, and a detection pool formed in the microfluidic biochip, the sample inlet, the detection pool, and the communication port being connected in sequence by means of a microfluidic channel to allow a sample fluid in contact with the sample inlet to enter the microfluidic channel and flow into the detection pool by means of the microfluidic channel; and a detection mechanism used for detecting the detection pool after the sample fluid in the detection pool reacts with a detection reagent in the detection pool to obtain a preset detection parameter of the sample fluid.
    Type: Grant
    Filed: September 9, 2021
    Date of Patent: November 14, 2023
    Inventors: Haoquan Liu, Bin Fei, Bintang Zhao, Jing Wang