Abstract: Fluorenes bearing a 9-aminoalkyl substituent are useful antiarrhythmic agents. Pharmaceutical formulations containing such compounds are provided, as well as a method of treatment.

Abstract: Aromatic nitrile-containing compounds are provided of the formula: ##STR1## where n is 1 or 2; R is selected from H, Cl, Br, NO.sub.2, a lower alkyl group containing from 1 to about 4 carbon atoms, and a lower alkoxy group containing from 1 to about 4 carbon atoms; R.sub.1 is selected from H and CH.sub.3 ; and R.sub.2 is selected from CH.sub.2 CH.sub.2 CN, an alkyl group containing from 1 to about 6 carbon atoms and: ##STR2## where R.sub.1 has the value given above.

Abstract: Subjecting 1,4-bis-[(pyrrolin-3-onyl)methylamino]-2-butyne to ultraviolet irradiation effects rearrangement in greater than 80% yield to 1,4-bis-[(isocyanatocycloprolpyl)methylamino]-2-butyne. The diisocyanate is useful in the synthesis of polyurethanes and polyureas and also for the in situ photochemical generation of a cross-linking agent for polyurethanes and structurally related polymers.

Abstract: A process for the production of tertiary benzyl isocyanates by reaction of the corresponding olefin with a carbamoyl halide to form the benzyl halide followed by the reaction of the benzyl halide with an excess of isocyanic acid to form the isocyanate and carbamoyl halide which can be recovered and recycled.

Abstract: The invention provides a process for the preparation of ortho- and para-hydroxybenzyl cyanides. The process of the invention comprises the reaction of an aromatic alcohol selected from ortho- and para-hydroxybenzyl alcohols with a cyanide reagent and an ester capable of esterifying the hydroxyl group of the benzyl alcohol.In a preferred form of the process there is employed a route via the reaction of an ortho- or para-hydroxybenzyl formate with a cyanide reagent preferably selected from sodium and potassium cyanides.

Abstract: The invention relates to cyclopropanecarboxylic acid esters of the formula ##STR1## wherein X.sub.1 is methyl or halogen, R.sub.1 is hydrogen, cyano, --CSNH.sub.2, allenyl, C.sub.2 -C.sub.3 alkenyl or C.sub.2 -C.sub.3 alkynyl, and R.sub.2 is unsubstituted or substituted alkenyl or alkynyl.A process for obtaining these compounds and their use in pest control are also disclosed.

Abstract: Herbicidal compositions comprising or consisting of a compound of the formula ##STR1## in which R is an aliphatic, straight chain, branched or cyclic, saturated or unsaturated hydrocarbon residue of 1 to 6 carbons, R.sub.1 is hydrogen or methyl, R.sub.2 is cyanoalkyl or alkoxyalkyl, R.sub.3 is the same or different if more than one and is hydrogen, alkyl, alkoxy, alkylthio or halogen and n is 1 or 2. The compounds have a broad soil and leaf herbicidal effect and are suited particularly for selective weed suppression in cultures like soybeans, peas, alfalfa, potatoes, maize, sorghum, rice, wheat and barley.

Abstract: The invention relates to .alpha.-isopropyl- and .alpha.-cyclopropylphenylacetates of the formula ##STR1## wherein R.sub.1 is hydrogen, cyano, --CSNH.sub.2, allenyl, C.sub.2 -C.sub.3 alkenyl or C.sub.2 -C.sub.3 alkynyl, R.sub.2 is unsubstituted or substituted alkenyl or alkynyl, R.sub.3 is isopropyl or cyclopropyl, and each of R.sub.4 and R.sub.5 is halogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 haloalkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 haloalkoxy, or both together are the methylenedioxy radical.A process for the production of these compounds and their use in pest control are disclosed.

Abstract: A method for the alkylation of certain substituted phenylacetonitriles with alkylhalides in the presence of solid particulated alkali metal hydroxides under essentially anhydrous conditions. Trialkylamine catalysts may optionally be utilized. Compounds obtained by this method, some of which are valuable intermediates in the preparation of pyrethroid pesticides, are described.

Abstract: A process for producing aromatic mono- and polyisocyanates by the addition reaction of isocyanic acid with vinyl aromatics is disclosed. The process is characterized by the slow addition of the olefin to a reaction mass of solvent and isocyanic acid to maintain the isocyanic acid in high excess to unreacted olefin.

Abstract: The invention relates to 3-phenoxybenzyl compounds of the formula ##STR1## wherein R.sub.1 is hydrogen, cyano, --CSNH.sub.2, C.sub.2 -C.sub.3 alkenyl or C.sub.2 -C.sub.3 alkynyl and R.sub.2 is alkenyl or alkynyl, as intermediates for the production of biocides.The preparation of the 3-phenoxybenzaldehydes employed as intermediates is described. Novel 3-phenoxybenzaldehydes used as starting materials and the production thereof are also disclosed.

Abstract: 4-Fluoro-3-phenoxy-benzyl 3-alken-1-yl-2,2-dimethylcyclopropanecarboxylates have the general formula ##STR1## wherein R represents alkyl or alkenyl,R.sup.1 represents hydrogen or alkyl, with the proviso that R and R.sup.1 are different, andR.sup.2 represents hydrogen, cyano or alkyl, alkenyl or alkynyl having in each case up to 4 carbon atoms,are obtained if 3-alken-1-yl-2,2-dimethyl-cyclopropanecarboxylic acids of the general formula ##STR2## wherein R and R.sup.1 have the meaning given above, or reactive derivatives of these acids, are reacted with 4-fluoro-3-phenoxy-benzyl alcohols of the general formula ##STR3## wherein R.sup.2 has the meaning given above, or with reactive derivatives of these alcohols, if appropriate in the presence of an acid acceptor and/or catalyst, and if appropriate using a diluent. The compounds of the formula (I) have a high pesticidal activity, especially against insects or acarids.

Abstract: The present invention relates to cyclopropanecarboxylates of the formula (I), ##STR1## wherein R and X may be same or different, each is a chlorine or bromine atom, and their production and use as an insecticide and/or acaricide.

Abstract: Novel N-(sulphenamide)-acyl isocyanates of the formula ##STR1## in which R.sup.1 represents a thrihalogenomethyl radical andR.sup.2 represents an aliphatic, cycloaliphatic, araliphatic, aromatic or heterocyclic radicalare useful as intermediates for reaction with amines to produce the corresponding fungicidally active biurets.

Abstract: 2'-Phenylhydrazino-2-cyanoacrylic acid esters of the formula ##STR1## wherein R.sup.1 is methyl, trifluoromethyl, chlorine or bromine, R.sup.2 is chlorine, bromine, iodine or methylsulfonyl, R.sup.3 is hydrogen, chlorine or bromine, or methoxy in the 5-position, in which case R.sup.1 and R.sup.2 are chlorine, or R.sup.3 is chlorine in the 3-position, in which case R.sup.2 is hydrogen, and R.sup.4 is alkyl of 1 to 3 carbon atoms, allyl or propargyl, and herbicides containing these compounds.

Abstract: The invention relates to a process for the production of chloroalkylsulfonyl isocyanates of the formula ##STR1## by a catalytically induced reaction of chlorosulfonyl isocyanate with one or more C.sub.2 -C.sub.4 -olefins. The reaction is carried out in a continuous manner in a tubular reactor.

Abstract: The disclosed [[2-(substituted amino)-2-phenylethyl]nitrosoamino]acetonitrile derivatives and the ring closed oxadiazolium salts thereof as well as their pharmaceutically acceptable acid addition salts are antihypertensive agents useful in the treatment of hypertension.

Abstract: A process is provided for hydroxyalkylation of cyanoethylanilines, which comprises reacting an alkylene oxide of the formula: ##STR1## wherein R.sub.1 is selected from H, Cl, Br, OH, a lower alkyl group containing from 1 to about 4 carbon atoms, or phenyl with a cyanoethyl aniline in a molar ratio of from about 1:1 to about 2:1 in a reaction medium at a temperature of from about 40.degree. C. to about 130.degree. C. in the presence of an acid catalyst provided in an amount sufficient to catalyze said reaction to thereby provide the corresponding hydroxyalkylated cyanoethyl aniline.

Abstract: Polymeric residue including toluene diisocyanate is combined with a solvent having a low affinity for polymer solution and a high affinity for toluene diisocyanate to dissolve toluene diisocyanate leaving the polymeric materials in suspension. The polymeric compounds are precipitated and filtered, the filtrate solution distilled and the toluene diisocyanate recovered as a pure product.

Abstract: The present invention relates to a process for the production of specific polyisocyanates by reacting diamines containing hydrogen atoms which are active in the context of the isocyanate addition reaction with excess quantities of organic diisocyanates. The invention also relates to a modification of the above process characterized in that the diamines are reacted first with excess quantities of a first diisocyanate after which the thus obtained reaction product which contains a urea group and a biuret group is reacted in a second stage with a second diisocyanate. The invention also relates to the use of polyisocyanates as the isocyanate component in the production of polyurethane plastics by the isocyanate-polyaddition process.