Abstract: A device for scanning measurement of the distance to an object comprises a light source that produces optical signals each having a varying frequency. An optical distribution matrix comprising optical switches and/or optical splitters distributes the optical signals simultaneously or successively onto optical output waveguides. A deflection optical unit deflects the optical signals when exiting from the optical output waveguides so that they are emitted in different directions from the device. A plurality of detectors detect a superposition of one of the optical signals produced by the light source with an optical signal which was reflected from the object. Input waveguides, which are independent of the output waveguides, guide the optical signals reflected from the object to the detectors while bypassing the optical distribution matrix. An evaluation unit determines a distance to the object from the superposition detected by the detectors.

Abstract: Closed-system sorting flow cytometer adapters for converting a sorting flow cytometer having a sort block into a closed-system sorting flow cytometer are provided. Adapters of interest include a sort block coupler for operably connecting to the sort block, an external chamber, and a connector for gaseously coupling the sort block to the external chamber, optionally via a sort bucket that is in cellular-receiving relationship with the sort block coupler. Flow cytometers having closed-system sorting flow cytometer adapters are also disclosed. Methods, computer systems and kits for carrying out the invention are additionally provided.

Abstract: Disclosed are an ultrafast electric pulse generation and detection device and a use method thereof. The device includes a laser and an electric pulse generator. The electric pulse generator includes: a photoelectric material layer including an optically controlled switching region for responding to excitation light generated by the laser; an insulating layer formed on the photoelectric material layer, wherein a switch structure exists at a position of the insulating layer corresponding to the optically controlled switching region, so that the optically controlled switching region is partially exposed or completely exposed; transmission lines are formed on the insulating layer.

Abstract: An imaging device and method for imaging an object, such as for multispectral or hyperspectral imaging, are disclosed. The imaging device includes an image sensor located in an image plane of the imaging device. The image sensor includes photosensitive elements. A first imaging system is configured to generate an intermediate image of the object in an intermediate image plane. A second imaging system is configured to generate an image of the intermediate image on the image sensor in the image plane. A diffractive optical element is arranged in the intermediate image plane. An aperture is arranged in a beam path of the second imaging system between the intermediate image plane and the image sensor. The diffractive optical element, the second imaging system, and the aperture are arranged such that different images for different wavelengths of the intermediate image are generated on different groups of the photosensitive elements.

Abstract: A characteristic information extraction method of a small-molecule volatile substance, including: dividing a surface-enhanced Raman scattering (SERS) spectrum of the small-molecule volatile substance to obtain n wavelength subintervals, where n is a positive integer; sampling the n wavelength subintervals through weighted bootstrap sampling (WBS) to obtain W wavelength subintervals, where W is a positive integer less than n; and screening the W wavelength subintervals to obtain desired wavelength subintervals. This application also provides a rapid detection method and a portable detection system of a small-molecule volatile substance.

Abstract: Methods, systems and devices are described that enable measurement and characterization of complex laser pulses by relying on three interferograms that are measured simultaneously. The described three-phase spectral interferometry (3PSI) can meet the growing demand for optical recorders with long record and 1 ps or finer resolution. An example three-phase interferometric system includes a three-output optical splitter with a first input port to receive the input optical signal, a second input port to receive a reference optical signal with one or more unknown spectral characteristics. The three output ports of the optical splitter produce interferograms that correspond to relative phase shifts of substantially 120 degrees. Detectors are positioned to receive and measure the interferograms, which allows determination of the amplitude and phase of the input optical signal with very high accuracy.

Abstract: A three-dimensional profiler includes a broadband radiation source. An interferometric system receives the radiation and includes first and second beam splitters, a moving time delay-inducing reflector, and a stationary reflector. The interferometric system creates a time-delayed optical sample radiation source and an optical reference incident radiation source with the first beam splitter. A stationary sample holder receives the optical sample incident radiation. A reference plane receives the optical reference incident radiation. A detector receives an interference signal from reflected or scattered optical sample radiation and reflected or scattered optical reference radiation. A processor extracts an optical path difference between the reference plane and the sample and reconstructs a three-dimensional morphology of the sample.

Abstract: An optical measurement apparatus includes a light source unit generating and outputting light, a polarized light generating unit generating polarized light from the light, an optical system generating a pupil image of a measurement target, using the polarized light, a self-interference generating unit generating multiple beams that are split from the pupil image, and a detecting unit detecting a self-interference image generated by interference of the multiple beams with each other.

Abstract: This flow cytometer includes a flow path through which an observation object flows with a fluid; an optical illumination system including a spatial optical modulation device, and a first optical element; and an optical detection system including a first light detector, wherein the optical illumination system further includes a first spatial filter disposed in a first optical path between a light source and an image position of light imaged in the flow path by the first optical element and having a first region which hinders traveling of light emitted from the light source towards the observation object, the optical detection system further includes a second light detector disposed in a second optical path between the first light detector and the image position and having a second region which directs the light modulated by the observation object towards the first light detector, and the position of the first region and the position of the second region are in a substantially optically conjugate relationship.

Abstract: Described here are optical sampling architectures and methods for operation thereof. An optical sampling architecture can be capable of emitting a launch sheet light beam towards a launch region and receiving a detection sheet light beam from a detection region. The launch region can have one dimension that is elongated relative to another dimension. The detection region can also have one dimension elongated relative to another dimension such that the system can selectively accept light having one or more properties (e.g., angle of incidence, beam size, beam shape, etc.). In some examples, the elongated dimension of the detection region can be greater than the elongated dimension of the launch region. In some examples, the system can include an outcoupler array and associated components for creating a launch sheet light beam having light rays with different in-plane launch positions and/or in-plane launch angles.

Abstract: A device is for analyzing a heterogeneous sample (S). The device includes a measurement module having a reservoir configured to accommodate the sample (S), a first infrared spectroscopy subassembly and a second fluorescence spectroscopy subassembly. The first subassembly includes a diffusing optical element which is positioned so as to allow the implementation of reliable infrared spectroscopy measurements with a high precision without degrading the fluorescence spectroscopy measurements which take place on the same sample. The device includes a processing module connected to the measurement module by a communication network and a processor configured to analyze the data obtained by infrared spectroscopy and fluorescence spectroscopy.

Abstract: Apparatus and methods for spectral analysis of a sample are described, for example for carrying out Raman or other optical or spectroscopic analysis of samples such as pharmaceutical dosage forms, including oral solid dosage forms such as tablets or capsules. Such apparatus may comprise delivery optics arranged to direct probe light to a delivery region of the sample, collection optics arranged to collect probe light scattered from a collection region of the sample, and a spectrometer having an entrance port, the spectrometer being arranged to receive the collected probe light from the collection optics at the entrance port of the spectrometer, and to detect spectral features in the received probe light. In particular, the collection optics may comprise Koehler integration optics arranged to process the collected probe light such that the collected light from each point of the collection region is distributed across the entrance port of the spectrometer.

Abstract: The inventive concept relates to an apparatus for treating a substrate. The apparatus includes a liquid supply unit that supplies a liquid to a substrate, a cover that is formed of a light transmitting material and installed on a component provided in the liquid supply unit and that provides an inspection area, and an inspection unit that inspects bubbles contained in the liquid flowing in the component provided in the inspection area. The inspection unit includes a light source that applies light toward the inspection area from outside the cover, a light receiving part that is located outside the cover and that receives the light passing through the inspection area, and an inspection part that inspects the bubbles from the light received by the light receiving part.

Abstract: Provided herein are interference objective modules comprising an objective, and an interference module comprising a reference plate disposed apart from the objective to provide a reference arm, a beam splitter to split a source light processed from the objective, and a sample plate to translate the split light from the beam splitter to provide a sample arm, wherein the interference module is configured to make a distance of a focal plane and an interference plane of the interference objective module varied during a measurement, and wherein the focal plane and the interference plane of the interference objective module intersect during the measurement.

Abstract: A filter array includes optical filters arranged in two dimensions. The optical filters include a first filter and a second filter. The first filter includes a first multimode filter having, within a target wavelength range, first peak wavelengths at each of which the optical transmittance is at a local maximum, and a first band-limiting filter having, as a limiting band, a first sub-wavelength range that is a part of the target wavelength range. The second filter includes a second multimode filter having, within the target wavelength range, second peak wavelengths at each of which the optical transmittance is at a local maximum, at least one of the second peak wavelengths being different from the first peak wavelengths, and a second band-limiting filter restricting transmission of light in a second sub-wavelength range that is a part of the target wavelength range and that is different from the first sub-wavelength range.

Abstract: The present disclosure pertains to two-photon microscopy, and specifically to methods and systems for optimizing the performance of entangled two-photon absorption (ETPA) microscopy. An ETPA microscope is described with time delay tunability to optimize the coincidence of entangled photons on a sample. The optimization allows for increased two-photon absorption by the sample, resulting in increased luminescence of the sample. The ETPA microscopy systems and methods described allow for nonlinear imaging using excitation energy intensities six orders of magnitude lower than comparable two-photon absorption microscopy techniques using classical light.

Abstract: A computer implemented methods for estimating at least one quality function of a given layered coating on a transparent substrate allows to predict at least one non in-process measured quality function of a given layered coating on a transparent substrate from an in-process measured quality function which can be acquired on the coated substrate as deposited at any location, preferably at the end of a coating process. The method allows to get rid of in-process real-time continuous measurements of quality functions of the coated transparent substrate and real-time monitoring of coating process parameters.

Abstract: A filter and a miniature spectrum measuring device are provided. The filter includes a plurality of film structures. Each of the film structures includes an H-type structural film, an L-type structural film, and a cavity film disposed between the H-type structural film and the L-type structural film.

Abstract: A spectroscopic assembly may include a spectrometer. The spectrometer may include an illumination source to generate a light to illuminate a sample. The spectrometer may include a sensor to obtain a spectroscopic measurement based on light, reflected by the sample, from the light illuminating the sample. The spectroscopic assembly may include a light pipe to transfer the light reflected from the sample. The light pipe may include a first opening to receive the spectrometer. The light pipe may include a second opening to receive the sample, such that the sample is enclosed by the light pipe and a base surface when the sample is received at the second opening. The light pipe may be associated with aligning the illumination source and the sensor with the sample.

Abstract: In some examples, fiber optic cable location may include transmitting a coherent laser pulse into a device under test (DUT). Based on an analysis of reflected light resulting from the transmitted coherent laser pulse, changes in intensity of the reflected light caused by a plurality of signals directed towards the DUT may be determined. Further, based on the changes in intensity of the reflected light, a location of the DUT may be determined.