Patents Examined by Dominic Lazaro
  • Patent number: 12213484
    Abstract: The present invention relates to solvent-free aqueous suspension concentrates having high active ingredient concentration, good biological efficacy and good rheological stability, and to processes for production thereof. The formulations of the invention are suitable for the field of plant protection.
    Type: Grant
    Filed: April 12, 2019
    Date of Patent: February 4, 2025
    Assignee: BAYER AKTIENGESELLSCHAFT
    Inventors: Gorka Peris, Pierre Philippe Haas, Stefan Herrmann
  • Patent number: 12208116
    Abstract: The invention concerns biocompatible polymer systems comprising at least one polymer with a plurality of pores, said polymer comprising a sulfonic acid salt functionality designed to adsorb a broad range of protein based toxins from less than 0.5 kDa to 1,000 kDa and positively charged ions including but not limited to potassium.
    Type: Grant
    Filed: June 30, 2023
    Date of Patent: January 28, 2025
    Assignee: CytoSorbents, Inc.
    Inventors: Thomas Golobish, Maryann Gruda, Tamaz Guliashvili, Pamela O'Sullivan, Andrew Scheirer, Vi Dan, Wei-Tai Young, Vincent Capponi, Phillip Chan
  • Patent number: 12201660
    Abstract: The present disclosure relates to a herbo-mineral kit for alleviating adverse effects of chemotherapy resulting into improved quality of life of patients. The herbo-mineral kit comprises a first container containing Padmakadi Ghrut (PDG) in a thick, viscous form; a second container containing Mouktikyukta Kamdudha Vati (MKD) in a solid dosage form; a third container containing Praval Pishti Vati (PPV) in a solid dosage form; and a fourth container containing Ananta vati in a solid dosage form. The herbo-mineral kit of the present disclosure can be used for alleviating adverse effects of chemotherapy such as nausea, vomiting, constipation, diarrhea, stomatitis, and skin discoloration in cancer treatment. Use of the herbo-mineral kit of the present disclosure may prove to be beneficial in all types of cancers and diseases for which chemotherapy is treatment of choice.
    Type: Grant
    Filed: February 12, 2020
    Date of Patent: January 21, 2025
    Inventor: Sadanand Prabhakar Sardeshmukh
  • Patent number: 12186449
    Abstract: The disclosure herein relates to photoinitiated dermal fillers, hyaluronic acid-rhCollagen double crosslinked dermal fillers and hyaluronic acid-rhCollagen semi interpenetrated network, each comprising plant-derived human collagen, as well as methods of using the same.
    Type: Grant
    Filed: October 12, 2023
    Date of Patent: January 7, 2025
    Assignee: CollPlant Ltd.
    Inventors: Oded Shoseyov, Nadav Orr, Jasmine Seror Maknouz, Revital Zarka
  • Patent number: 12171909
    Abstract: Provided is a compression resistant implant configured to fit at or near a bone defect to promote bone growth. The compression resistant implant comprises a biodegradable polymer in an amount of about 0.1 wt % to about 20 wt % of the implant and a freeze-dried oxysterol in an amount of about 5 wt % to about 90 wt % of the implant. Methods of making and use are further provided.
    Type: Grant
    Filed: November 24, 2021
    Date of Patent: December 24, 2024
    Assignee: Warsaw Orthopedic, Inc.
    Inventors: Benjamin T. Reves, David S. Scher, Roger E. Harrington, Jerbrena C. Jacobs
  • Patent number: 12168026
    Abstract: The present invention relates to large scale manufacture of nanoscale microsheets for use in applications such as wound healing or modification of a biological or medical surface.
    Type: Grant
    Filed: October 3, 2023
    Date of Patent: December 17, 2024
    Inventors: Nicholas L. Abbott, Jonathan F. McAnulty
  • Patent number: 12168033
    Abstract: A method for treating a disease condition such as inflammation, arthritis, joint pain, rheumatoid arthritis, osteoarthritis, chronic non-rheumatoid arthritis, and collagen degradation in a patient in need thereof involves administering to the patient an effective amount of a composition: a) a Tamarindus indica seed extract comprising an alcohol or hydroalcohol extract of a Tamarindus indica seed, wherein the alcohol or hydroalcohol extract comprises proanthocyanidins; and b) a Curcuma longa rhizome extract comprising curcuminoids, wherein the Tamarindus indica seed extract and the Curcuma longa rhizome extract are used in a ratio ranging from 1:4 to 4:1.
    Type: Grant
    Filed: September 30, 2021
    Date of Patent: December 17, 2024
    Assignee: LAILA NUTRACEUTICALS
    Inventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Venkata Kanaka Ranga Raju Gokaraju, Trimurtulu Golakoti, Kiran Bhupathiraju
  • Patent number: 12168108
    Abstract: Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent.
    Type: Grant
    Filed: October 12, 2023
    Date of Patent: December 17, 2024
    Assignee: Urotronic, Inc.
    Inventors: Lixiao Wang, Peter Barnett
  • Patent number: 12161685
    Abstract: A multi-efficacy traditional Chinese medicine compound composition and application thereof in pharmaceutical preparations are disclosed. The traditional Chinese medicine extracts are combined with the glucosamine, the collagen and the chondroitin sulfate, so that the multi-efficacy traditional Chinese medicine compound composition is prepared. The traditional Chinese medicine compound composition starts from improving the health of bone and joint and accompanying cardiovascular disease, selects the medicinal materials, and optimizes the extraction process of the traditional Chinese medicine for the diseases dominated by degenerative osteoarthritis. The disclosure has the efficacious of improving the symptoms of degenerative osteoarthritis, reducing blood pressure, improving the symptoms with osteoporosis, improving the symptoms with cardiovascular disease, improving the symptoms with urinary system disease, etc.
    Type: Grant
    Filed: March 26, 2021
    Date of Patent: December 10, 2024
    Inventors: Shengcan Zou, Zengliang Zhang, Min Wang, Zhuqing Liu, Sai Lu, Li Li, Shanglong Wang
  • Patent number: 12150930
    Abstract: The present invention relates to oral liquid formulations of Enzalutamide or pharmaceutically acceptable salt thereof and one or more pharmaceutically acceptable excipient. Further, the invention relates to providing an economical and technically advanced dosage form over existing dosage forms. In addition, the present invention also provides an improved process for preparation of Enzalutamide oral liquid formulation. The present invention further provides such compositions for the treatment of for the treatment of patients with metastatic castration-resistant prostate cancer who have previously received docetaxel.
    Type: Grant
    Filed: July 31, 2023
    Date of Patent: November 26, 2024
    Assignee: BDR Pharmaceuticals Int'l Pvt. Ltd.
    Inventors: Shah Dharmesh Mahendrabhai, Badiger Aravind Manappa, Sharma Mukeshkumar Subhashchandra, Trivedi Madhavkumar Dilipbhai, Choksi Rakshit Ketanbhai, Vora Pratik Ashwinbhai, Agrawal Vijay Ashok, Gandhi Prashant Kanaiyalal, Panchal Nimitkumar Harishchandra, Mori Nitin Merubhai, Jayaswal Nilay Manikant, Darji Hirenkumar Jitendrakumar
  • Patent number: 12151045
    Abstract: Compositions and methods related to powdered hemostats that crosslink during and/or after application to a bleeding site are described. The compositions may comprise a first component comprising a multifunctionalized polymeric composition (e.g., multifunctionalized polyethylene glycol) functionalized with electrophilic reactive groups, and a second component that comprises a protein such as albumin. The compositions may in certain applications act as hemostats when applied in dry powder form to a bleeding wound, whereupon the first component and the second component of the composition crosslink to form a hydrogel.
    Type: Grant
    Filed: December 27, 2021
    Date of Patent: November 26, 2024
    Assignee: Davol Inc.
    Inventors: Keith Greenawalt, Frederick H. Strickler, Jr.
  • Patent number: 12121031
    Abstract: The present invention provides a magnetic biochar-quaternary phosphonium salt bactericidal material, a preparation method therefor and usage thereof, and belongs to the field of water treatment. The preparation method comprises: 1) using corn straw biochar as a precursor to prepare magnetic biochar by a co-precipitation method; and 2) adding the magnetic biochar into deionized water, then adding a quaternary phosphonium salt, performing the magnetic stir at room temperature, raising the temperature after sufficient impregnation, carrying out a hydrothermal reaction, and then cooling to the room temperature to obtain the bactericidal material. The temperature is raised to 60° C.˜70° C.
    Type: Grant
    Filed: April 21, 2020
    Date of Patent: October 22, 2024
    Assignee: INSTITUTE OF SOIL SCIENCE, CHINESE ACADEMY OF SCIENCES
    Inventors: Fang Wang, Yuhao Fu, Hongjie Sheng, Yongrong Bian, Xin Jiang
  • Patent number: 12115187
    Abstract: Ready-to-use (RTU) Sodium Phosphates solutions for phosphorus replacement therapy are presented that include Sodium phosphate with/without sodium chloride at a fixed volume with 1.5 to 15 mmol/100 mL phosphorus, no more than 20 mEq/100 mL Sodium and less than 50 mcg/L aluminum.
    Type: Grant
    Filed: May 17, 2024
    Date of Patent: October 15, 2024
    Assignee: Nivagen Pharmaceuticals, Inc.
    Inventors: Niravbhai Jayantibhai Patel, Robert Miller, Maheshkumar Kalubhai Bhalaria, Rucha Abhijit Kelekar, Brijeshkumar B Pandya, Sunil Dnyanu Khandekar, Sudhir Shantarum Jagdale, Dasaradhi Lakkaraju, Jay Shukla
  • Patent number: 12115286
    Abstract: Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent.
    Type: Grant
    Filed: June 17, 2022
    Date of Patent: October 15, 2024
    Assignee: Urotronic, Inc.
    Inventors: Lixiao Wang, Peter Barnett, David Hendrickson
  • Patent number: 12115235
    Abstract: The disclosure relates to oral delivery compositions that transition from a flowable state to a hardened or semi-hardened state. The flowable hardening composition may be delivered to oral tissues, including teeth and/or gums, directly or using a barrier strip or a tray-like device. Such compositions may be configured as a multi-part system wherein reactive materials (e.g., catalyst and reactive resins) are kept separate until use. Dispersion of the agents in a viscous carrier within the hardened composition enables a gradual release the desired agent(s) to reduce or eliminate sensitivity that may be caused by certain agents (e.g., dental whitening agents). The hardened delivery composition may include a reverse image of the oral tissue, allowing it to be removed and replaced multiple times during a single use, giving users more flexibility during treatment.
    Type: Grant
    Filed: February 1, 2023
    Date of Patent: October 15, 2024
    Assignee: ULTRADENT PRODUCTS, INC.
    Inventors: Brittany Shepler, Andy Kawamoto
  • Patent number: 12108759
    Abstract: The present invention relates to antibacterial carbon dots, having aminoguanidine functionality on their outermost surface. The invention further relates to the synthesis of said antibacterial carbon dots, and to the uses of these carbon dots for inhibiting a biofilm formation in the presence of said carbon dots and as fluorescent labeling markers for specific bacteria.
    Type: Grant
    Filed: October 31, 2019
    Date of Patent: October 8, 2024
    Assignee: B.G. NEGEV TECHNOLOGIES & APPLICATIONS, LTD., AT BEN-GURION UNIVERSITY
    Inventors: Raz Jelinek, Sagarika Bhattacharya, Gil Otis
  • Patent number: 12102737
    Abstract: Embodiments of the present invention provide a method of treating a stricture in a nonvascular body lumen such as urethral strictures, benign prostatic hyperplasia (BPH) strictures, ureteral strictures, esophageal strictures, sinus strictures, and biliary tract strictures. Embodiments of the present invention provide a method for treating at least one of benign prostatic hyperplasia (BPH), prostate cancer, asthma, and chronic obstructive pulmonary disease (COPD). The method can include delivering, for example, via drug coated balloon catheters, anti-inflammatory and anti-proliferative drugs (e.g., rapamycin, paclitaxel, and their analogues) and one or more additives.
    Type: Grant
    Filed: June 26, 2023
    Date of Patent: October 1, 2024
    Assignee: Urotronic, Inc.
    Inventors: Lixiao Wang, Peter Barnett
  • Patent number: 12104041
    Abstract: Biodegradable resin particles including a polyhydroxy alkanoate. In the biodegradable resin particles, an amount of a Ca component present in the particles is 10 to 10,000 ppm, the biodegradable resin particles have a volume average particle diameter of 2 to 50 ?m, the biodegradable resin particles have a BET specific surface area of 0.8 to 10 m2/g, and the biodegradable resin particles have a linseed oil absorption of 50 to 300 ml/100 g. The resin particles of the present invention can be suitably used by being included in an external preparation, such as a cosmetic or a quasi-drug.
    Type: Grant
    Filed: June 25, 2020
    Date of Patent: October 1, 2024
    Assignee: SEKISUI KASEI CO., LTD.
    Inventors: Kengo Nishiumi, Shinya Matsuno
  • Patent number: 12083200
    Abstract: Zinc oxide particles are prepared as a dry powder through a vapor phase formed by a plasma process, or by introducing defects into stoichiometric zinc oxide particles in a liquid carrier through mechanical stress. The zinc oxide has an O:Zn ratio of at least 0.99, an average particle size of 10 to 300 nm, and a sufficient concentration of oxygen vacancies and zinc vacancies to give a dispersion of the particles in C12-C15 alkyl benzoate an orange to tan color corresponding to a ?E value of at least 15 in a Dispersion Color Test. The particles contain no aggregates and have no detectable particles 500 nm or larger, on a number-weighted basis.
    Type: Grant
    Filed: April 24, 2023
    Date of Patent: September 10, 2024
    Assignee: Nanophase Technologies Corporation
    Inventors: Harry W. Sarkas, Christopher C. Boffa
  • Patent number: 12076389
    Abstract: The invention relates to medicine and veterinary medicine, and more specifically to pharmacology, and can be used to prevent viral infections caused be RNA viruses that have a lipid capcid. An agent for prevention viral infections comprises viral material from RNA viruses that have a lipid capcid and stabilized colloidal selenium at a 1:1 ratio. The viral material from RNA viruses has titres of 6.0-8.0 lg TCD50/ml. To obtain colloidal selenium having particle sizes from 10 to 15 nm the colloidal selenium is stabilized with polyethylene glycol, and for colloidal selenium having particle sizes from 20 to 40 nm, the colloidal selenium is stabilized with cysteine.
    Type: Grant
    Filed: April 18, 2019
    Date of Patent: September 3, 2024
    Inventors: Vladislav Nikolaevich Laskavy, Sergei Ivanovich Ivanenko