Abstract: A functional food including a supplement composition in which the supplement composition includes a non-winterized marine source oil.

Abstract: The present invention relates to a core-shell network structure formed using a biocompatible biopolymer and to a composition comprising same. Said structure can be used as an alternative to synthetic chemical materials, such as polyethylene glycol (PEG), to effectively disperse an insoluble effective substance within a composition, thus addressing safety issues, and formulations can be preserved stably for a long time through said network structure. Furthermore, said structure and the composition comprising same may provide useful benefits for the skin in terms of skin barrier enhancement, skin moisturization, skin regeneration, or the like.

Abstract: A compound 4-bromo-2-(quinolin-2-yliminomethyl)-phenol imine]-Ru(III)-phenanthroline complex, its synthesis, and its use for pharmaceutical applications.

Abstract: This invention illustrates a composition which has a high antioxidant power in cosmetic products. The composition includes a combination of two critical ingredients, originating from two natural superfood products: olive and kale. This current technology utilizes the sprout of kale, instead of the whole plant, as one ingredient. In the perspective of olive extract, it is either in the form of a concentrated liquid syrup of olive tree and leaf, which is enriched with natural polyphenols, especially with high content of hydroxytyrosol, or in the form of pure liquid hydroxytyrosol. An enhanced antioxidant power is observed when incorporating the kale sprouts together with the olive leaf extract.

Abstract: Resorbable implants comprising poly(butylene succinate) and copolymers thereof have been developed. The implants are preferably sterilized, and contain less than 20 endotoxin units per device as determined by the limulus amebocyte lysate (LAL) assay, and are particularly suitable for use in procedures where prolonged strength retention is necessary, and can include one or more bioactive agents. The implants may be made from fibers and meshes of poly(butylene succinate) and copolymers thereof, or by 3d printing, and the fibers may be oriented. Coverings and receptacles made from forms of poly(butylene succinate) and copolymers thereof have also been developed for use with cardiac rhythm management devices and other implantable devices. These coverings and receptacles may be used to hold, or partially/fully cover, devices such as pacemakers and neurostimulators.

Abstract: A W/O emulsion composition having excellent storage stability under temperature cycle conditions is provided. A W/O emulsion composition including the following components (A), (B), (C), (D) and (E): (A) a glycerol monofatty acid ester having 12 to 26 carbon atoms; (B) a higher alcohol having 10 to 22 carbon atoms; (C) a ceramide; (D) one or more selected from the group consisting of sphingosine, a salt thereof and an ionic surfactant; and (E) a nonionic surfactant including the following (e1) and (e2): (e1) one or more selected from the group consisting of a crosslinked polyether-modified silicone and a crosslinked polyglycerol-modified silicone and (e2) one or more selected from the group consisting of a polyether-modified silicone, a polyglycerol-modified silicone and a polyglycerol fatty acid ester.

Abstract: Implants with fillable reservoirs have been developed that are suitable for rhinoplasty, breast reconstruction, ear reconstruction, and replacement, reconstruction or repair of other soft tissues. The implants can be filled with graft material prior to implantation. The implants are preferably made from resorbable polymers, can be tailored to provide different geometries, mechanical properties and resorption rates in order to provide more consistent surgical outcomes. The implants preferably have an interconnected network of unit cells with microporous outer layers and optionally some or all of the unit cells having at least one macropore in their outer layers. The implants can be loaded by injection with microfat, collagen, DCF, cells, bioactive agents, and other augmentation materials, prior to implantation.

Abstract: The invention provides a neural electrode, including a current generation device, a first and a second electrode. The current generation device is connected to the first and second electrodes through a conductive metal wire respectively. At least one of the first and second electrodes is a graphene electrode. The graphene electrode has soft texture and desirable stability to tolerate the repeated pressing and folding treatment, very high charge injection efficiency, and desirable in vivo stability, and is configured to electrically stimulate tissues and organs such as hearts and nerves to promote electrical stimulation and repair of neurons, to further promote regeneration of neural functions. The invention further provides use of a mineralized three-dimensional porous graphene foam material to prepare a bone defect filler. The bone defect filler has desirable biological compatibility, promotes cell proliferation, and accelerates and induces osteogenic differentiation of bone marrow mesenchymal stem cells.

Abstract: The core active components of the present composition, termed as de-ironizing inducers (DII), has a reducing agent and a precipitating agent. Molar ratios of the reducing agent with the precipitating agent range from 1:3-6 and the core components in the skincare product range from 0.1% to 10% w/w. The pH value of the skincare product is between 6.6 and 7.4. The skin care products can safely and effectively 5 remove iron in the skin, which has been shown to accelerate the visible signs of aging. The core components can also be used in combination with conventional skincare product compounds to achieve better anti-aging effects.

Abstract: A drug delivery system is provided in the form of a controlled release, bioerodible pellet for subdermal implantation. The pellet is bioerodible, and provides for the sustained release of a pharmacologically active agent over an extended time period. As such, the drug delivery system finds significant utility in chronic drug administration. Bioerosion products are water soluble, bioresorbed, or both, obviating the need for surgical removal of the implant. Methods for manufacturing and using the drug delivery system are also provided.

Abstract: A catheter (1) resector balloon (8) used in the treatment of any type of endoluminal-endobronchial tumoral or non-tumoral narrowing and occlusions and endovascular obstructions seen in the hollow tubular organs such as the trachea, esophagus, urinary tract, biliary tract, etc. and vessels, characterized in that, it comprises the following; at least one flexible pad section with pressure and proximity sensor and/or pad section without pressure and proximity sensor which provides soft stopping at the final wall section where the catheter (1) resector balloon (8) is applied in a soft, flexible and shock absorber manner at the tip (2) portion, prevents punctures, tears, bursts or vascular damages occurred in the tissues and vessels formed as a region, undesired complications, provides stopping without giving any damage to its location.

Abstract: An anhydrous and alcohol-free cosmetic product having a silky feel containing: 10 to 99, preferably 40 to 90, percent by weight dimethicone crosspolymer gel dispersed in a non-silicone fluid; and 1 to 30 percent by weight lipophilic actives, fragrance oils, or a combination thereof. The product can also contain 1 to 90 percent by weight non-silicone fluid to adjust the viscosity. This solvent can be volatile to produce a dry feel on the skin. One or more emollients can be used to moisturize the skin or to increase the miscibility of the actives and fragrance. Moreover, a preservative and some pigments can be added to the formula to preserve the product from bacteria contamination and to improve the aesthetics. The product can be used with a variety of cosmetic or fragrance products such as creams, gels, and lotions.

Abstract: The present invention relates to the field of antibodies useful in therapy and diagnosis. It specifically discloses bioconjugates comprising one or more antibodies bound to functionalized, magnetic nanoparticles. These bioconjugates are useful in cancer therapy, particularly for removing circulating tumor cells. The invention further pertains to specific functionalized, magnetic nanoparticles and to the manufacturing of such bioconjugates and such functionalized, magnetic nanoparticles.

Abstract: Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent.

Abstract: Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent.

Abstract: Provided are single-dose, ready-to-use formulations and methods for preparing the formulations that include a compound of Formula (I) including pharmaceutically acceptable salts and amorphous and polymorph forms thereof.

Abstract: This invention provides antibacterial and antiviral compositions and methods. The compositions possess prolonged and powerful antibacterial/antiviral functions under light exposure and even under completely dark conditions, while daylight exposures could recharge the functions repeatedly. In some embodiments, compositions of the invention can be employed in personal protective equipment (PPE) such as face masks, biologically self-cleaning air and water filters, medical devices, and products. The biocidal PPE can prevent transmission of infectious diseases such as Ebola and respiratory viruses. In some embodiments, compositions of the invention can be employed in food protectant materials to provide antimicrobial and antiviral bio-protection during food transportation and storage.

Abstract: The invention relates to a method for mending split ends of hair comprising contacting the hair with split ends with a composition comprising at least cationic polygalactomannan containing non-ionic hydroxyalkyl substituents and having a Brookfield RVT viscosity at 25° C. and 20 rpm greater than 700 mPa·s, at a concentration of 1 pbw in water, for instance comprised between 700 and 1,200 mPa·s.

Abstract: The porous-cellulose particles according to the present invention are constituted by gathered crystalline celluloses having a type I crystal form including a glucose molecule as a constitutional unit. That is, porous-cellulose particles having high sphericity have been achieved from a natural raw material. The porous-cellulose particles have an average particle diameter of 0.5 to less than 50 ?m, a specific surface area of 50 to 1000 m2/g, and a sphericity of 0.85 or more. Cosmetic products containing such porous-cellulose particles have excellent texture properties.

Abstract: Euphorbia dendroides silver nanoparticles can have a crystalline structure and an average particle size ranging from about 7 nm to about 13 nm. The Euphorbia dendroides silver nanoparticles may be synthesized by providing a Euphorbia dendroides extract and combining the Euphorbia dendroides extract with silver nitrate. The resultant Euphorbia dendroides silver nanoparticles may be useful in treating a variety of conditions including bacterial infections, diabetes, inflammation, and cancer.