Abstract: A method for making at least 2 kg (dry weight) of a lactic acid bacteria composition formulated with from 1% to 50% of ascorbate or ascorbic acid (w/w?dry matter) as antioxidant, wherein the pH is controlled so 3?pH?8 during at least the majority of the fermentation process by addition of a base not comprising NH3 (ammonia).
Abstract: Processes using Allium tissue homogenates and extracts in a simple and cost-effective manner to maximize the yields and recovery of thiosulfinates from Allium tissues and related organisms possessing alliinase, LF synthase and/or S-alk(en)yl-L-cysteine sulfoxides are disclosed.
Abstract: Provided is an age-related apolipoprotein B oxidase (apoBNOX) found tightly associated with the low-density lipoprotein particles and believed to be responsible for oxidizing lipoprotein particles and initiating atherogenesis. It causes damage by directly oxidizing the apolipoprotein B protein and indirectly oxidizing the lipids in the particles due to superoxide formation by the apoBNOX and its conversion into hydrogen peroxide. apoBNOX activity is inhibited by tyrosol and hydroxytyrosol and components of white wine, important components of French and Mediterranean diets, which seem to be a very good source of inhibitors of the apolipoprotein B oxidase. Agents comprising at least one naturally-occurring apoBNOX inhibitor and compositions lessen, ameliorate or treat disorders and complications resulting from cell damage caused by oxidation of apolipoprotein B.
Abstract: The present invention generally relates to the field of obesity. In particular the present invention relates to the use of probiotics to support weight management and to treat or prevent obesity. One embodiment of the present invention relates to the use of Lactobacillus helveticus CNCM I-4095 for the preparation of a composition to support weight management, promote weight loss and/or to treat obesity.
Type:
Grant
Filed:
February 4, 2010
Date of Patent:
June 4, 2013
Assignee:
Nestec S.A.
Inventors:
Fabrizio Arigoni, Christian Darimont-Nicolau, Catherine Mace
Abstract: There is provided an anti-cancer composition comprising an aquatic microbial extract, and there is more particularly provided an anti-cancer composition comprising a Bacillus sp. strain extract.
Type:
Grant
Filed:
June 26, 2008
Date of Patent:
May 14, 2013
Assignee:
Ajou University Industry-Academic Cooperation Foundation
Abstract: The present invention generally relates to the field of obesity. In particular the present invention relates to the use of probiotics to treat obesity. One embedment of the present invention relates to the use of Lactobacillus rhamnosus CGMCC 1.3724 and/or Lactobacillus rhamnosus NCC 4007 for the preparation of a composition to support weight management, promote weight loss and/or to treat obesity.
Type:
Grant
Filed:
July 24, 2008
Date of Patent:
May 14, 2013
Assignee:
Nestec S.A.
Inventors:
Christian Darimont, David Philippe, Catherine Mace, Fabrizio Arigoni
Abstract: An embodiment of the present invention is a Trichoderma atroviride SC1, CBS no 122089, as a biocontrol agent, i.e. to treat fungal diseases of plants. The second embodiment of the present invention is an agricultural composition comprising the Trichoderma atroviride SC1 as the active principle in an effective amount. The compositions of the present invention may further comprise a second biocontrol agent and/or an additive, an emulsifier, a plant nutrient, a wetting-agent, a plant micro-nutrient or a substratum, wherein said substratum is selected from the group consisting of: a nutrient culture medium, a cereal or a derivative thereof, an amendant, a vegetable or a part thereof, peat, wood or a piece thereof, clay or barks.
Type:
Grant
Filed:
March 21, 2008
Date of Patent:
April 30, 2013
Assignees:
Trentino Sviluppo S.p.A., Fondazione Edmund Mach
Abstract: There is presently provided a complex of a micelle formed from a cationic polymer and a protein, and a method using the complex to deliver the protein into a cell.
Type:
Grant
Filed:
April 30, 2008
Date of Patent:
April 23, 2013
Assignee:
Agency for Science, Technology and Research
Inventors:
Yi-Yan Yang, Yong Wang, Ashlynn Lingzhi Lee
Abstract: The present invention is directed to a microorganism having an ability of converting daidzein to equol in 24 hours of 50% or higher; a food/beverage or pharmaceutical composition containing the microorganism; an equol production method employing the microorganism; and a nucleic acid fragment which can specifically detect the microorganism.
Type:
Grant
Filed:
February 25, 2010
Date of Patent:
April 16, 2013
Assignee:
Kabushiki Kaisha Yakult Honsha
Inventors:
Hirokazu Tsuji, Koji Nomoto, Kaoru Moriyama, Hideyuki Akaza
Abstract: The disclosed subject matter relates generally to a method for modifying oil, and specifically to a process for increasing the concentration of polyunsaturated fatty acid in an oil composition.
Type:
Grant
Filed:
July 11, 2008
Date of Patent:
April 16, 2013
Assignee:
Ocean Nutrition Canada Limited
Inventors:
Jaroslav A. Kralovec, Weijie Wang, Colin James Barrow
Abstract: A pre-treatment method for analyzing a specified portion in a specimen composed of a biological tissue includes the steps of preparing a specimen to be analyzed, determining a specified portion in the specimen; and applying an analysis inhibitor to a portion except the specified portion of the specimen using a droplet spray method.
Type:
Grant
Filed:
May 1, 2008
Date of Patent:
April 9, 2013
Assignee:
Canon Kabushiki Kaisha
Inventors:
Yohei Murayama, Hiroyuki Hashimoto, Manabu Komatsu, Kazuhiro Ban
Abstract: Administration of an exogenous pulmonary surfactant in combination with antioxidant enzymes is effective for the prevention of bronchopulmonary dysplasia (BPD) and decreases the markers of pulmonary oxidative stress.
Abstract: The present invention relates to an improved culture medium and method for the enhanced growth and detection of Mycobacterium growth. The invention further relates to an improved mycobacterial reagent system or kit that can be used for the enhanced growth and detection of Mycobacterium.
Type:
Grant
Filed:
June 30, 2010
Date of Patent:
March 5, 2013
Assignee:
bioMérieux, Inc.
Inventors:
Parampal Deol, Leticia Barton, Yoany Portilla, Douglas Lovern
Abstract: The present invention relates to an improved culture medium and method for the enhanced growth and detection of Mycobacterium growth. The invention further relates to an improved mycobacterial reagent system or kit that can be used for the enhanced growth and detection of Mycobacterium.
Type:
Grant
Filed:
June 30, 2010
Date of Patent:
March 5, 2013
Assignee:
bioMérieux, Inc.
Inventors:
Parampal Deol, Leticia Barton, Yoany Portilla, Douglas Lovern
Abstract: The invention herein disclosed provides for compositions, methods for synthesizing said compositions, and methods for using said compositions, wherein the compositions and methods may be used to bind to and/or deactivate a poison oak oil, such as urushiol. The compositions and methods can be used to treat and/or reduce an inflammatory reaction and/or hypersensitivity to natural compounds found in poison oak, poison ivy, poison sumac, mango, lac tree, and cashew nut.
Type:
Grant
Filed:
May 13, 2009
Date of Patent:
March 5, 2013
Assignee:
The Regents of the University of California
Abstract: The present invention provides a method for producing a useful substance by supplying, to a fixed-bed reactor packed with an immobilized enzyme, a liquid mixture containing two liquid phases, in which the two liquid phases are allowed to flow in an identical, parallel direction, which method employs a fixed-bed reactor equipped with an insertion unit or tubes, so as to form a plurality of lumens in the fixed-bed reactor, each lumen having a cross section of a circular shape with a diameter of 100 mm or less or having a polygonal shape with a diagonal line of 100 mm or less, wherein the lumens are packed with an immobilized enzyme and the liquid mixture is supplied. In a reaction performed by passing a reaction mixture exhibiting two liquid phases through a fixed-bed reactor equipped with an immobilized enzyme, overall flow of the reaction liquid is made uniform.
Type:
Grant
Filed:
October 4, 2006
Date of Patent:
February 19, 2013
Assignee:
Kao Corporation
Inventors:
Jun Saito, Yoshitaka Senda, Toshiteru Komatsu
Abstract: Provided are methods for preparing gelled, solubilized extracellular matrix (ECM) compositions useful as cell growth scaffolds. Also provided are compositions prepared according to the methods as well as uses for the compositions. In one embodiment a device, such as a prosthesis, is provided which comprises an inorganic matrix into which the gelled, solubilized ECM is dispersed to facilitate in-growth of cells into the ECM and thus adaptation and/or attachment of the device to a patient.
Type:
Grant
Filed:
February 29, 2008
Date of Patent:
January 29, 2013
Assignee:
University of Pittsburgh—Of the Commonwealth System of Higher Education
Abstract: A process for stabilizing a bioactive composition includes forming hydrogel matrix pores around protein molecules and reducing a water content within the hydrogel matrix pores while keeping the protein molecules biologically active.
Type:
Grant
Filed:
June 18, 2012
Date of Patent:
January 29, 2013
Assignees:
Regents of the University of Minnesota, Toyota Motor Engineering & Manufacturing North America, Inc., Toyota Motor Corporation
Abstract: The present invention relates in general to edible compositions comprising probiotics. One embodiment of the present invention relates to an edible composition comprising Bifidobacterium longum ATCC BAA-999. This composition can be used to attenuate reductions in hippocampal BDNF expression and/or to treat or prevent anxiety and related disorders.
Type:
Grant
Filed:
April 8, 2009
Date of Patent:
January 1, 2013
Assignee:
Nestec S.A.
Inventors:
Gabriela Bergonzelli, Kurt Ornstein, Christine Cherbut
Abstract: A method for fabricating a micro-organ device comprises providing a microscale support having one or more microfluidic channels and one or more micro-chambers for housing a micro-organ and printing a micro-organ on the microscale support using a cell suspension in a syringe controlled by a computer-aided tissue engineering system, wherein the cell suspension comprises cells suspended in a solution containing a material that functions as a three-dimensional scaffold. The printing is performed with the computer-aided tissue engineering system according to a particular pattern. The micro-organ device comprises at least one micro-chamber each housing a micro-organ; and at least one microfluidic channel connected to the micro-chamber, wherein the micro-organ comprises cells arranged in a configuration that includes microscale spacing between portions of the cells to facilitate diffusion exchange between the cells and a medium supplied from the at least one microfluidic channel.
Type:
Grant
Filed:
March 28, 2008
Date of Patent:
January 1, 2013
Assignee:
The United States of America as represented by the Administrator of the National Aeronautics and Space Administration
Inventors:
Steve R. Gonda, Iris von Gustedt-Gonda, legal representative, Robert C. Chang, Binil Starly, Christopher Culbertson, Heidi L. Holtorf, Wei Sun, Julia Leslie