Patents Examined by Douglas F White
  • Patent number: 8334131
    Abstract: A a multivitamin and mineral dietary supplement includes a base composition of whole aphanizomenon flos-aqua, phycocyanin and phenylethylamine for promoting the body's natural production of stem cells. The production, support and maintenance of these stem cells is enhanced with vitamins and/or minerals. The vitamins and minerals when combined with the base composition promote good health, body repair and longevity.
    Type: Grant
    Filed: March 21, 2012
    Date of Patent: December 18, 2012
    Inventor: John V. Cappello
  • Patent number: 8329165
    Abstract: The present invention relates to a composition for the treatment of ballast water containing bacteriophage capable of killing specific target bacteria as an active ingredient in order to eliminate or reduce bacteria including pathogenic bacteria present in ballast water, and a biological treatment method of ballast water.
    Type: Grant
    Filed: September 5, 2008
    Date of Patent: December 11, 2012
    Assignee: Intron Biotechnology, Inc.
    Inventors: Seongjun Yoon, Sooyoun Jun, Sanghyeon Kang, Yunjaie Choi, Jeesoo Son
  • Patent number: 8318151
    Abstract: The present invention generally relates to the field of weight management and obesity. In particular the present invention relates to the use of probiotics in combination with prebiotics to treat or prevent obesity. One embodiment of the present invention relates to the use of Lactobacillus rhamnosus NCC 4007 in combination with a specific probiotic mixture for the preparation of a composition to support weight management, promote weight loss and/or to treat obesity.
    Type: Grant
    Filed: February 4, 2010
    Date of Patent: November 27, 2012
    Assignee: Nestec S.A.
    Inventors: Christian Darimont-Nicolau, David Philippe, Catherine Mace, Fabrizio Arigoni
  • Patent number: 8318150
    Abstract: The present invention generally relates to the field of obesity. In particular the present invention relates to the use of probiotics to support weight management and to treat or prevent obesity. One embodiment of the present invention relates to the use of Lactobacillus rhamnosus CNCM I-4096 for the preparation of a composition to support weight management, promote weight loss and/or to treat obesity.
    Type: Grant
    Filed: February 4, 2010
    Date of Patent: November 27, 2012
    Assignee: Nestec S.A.
    Inventors: Fabrizio Arigoni, Christian Darimont-Nicolau, Catherine Mace
  • Patent number: 8313744
    Abstract: The present invention relates to a composition comprising PKC agonist as an active ingredient. More precisely, the present inventors confirmed that absence seizure specific SWD was reduced by administrating PKC agonist into an animal model. Therefore, the composition of the present invention comprising PKC agonist as an active ingredient can be effectively used for the prevention and treatment of absence seizure and for the production of health improving functional food.
    Type: Grant
    Filed: August 5, 2010
    Date of Patent: November 20, 2012
    Assignee: Korea Institute of Science and Technology
    Inventors: Eunji Cheong, Hee-Sup Shin, Yihong Zheng, Kyoobin Lee, Jungryun Lee, Seongwook Kim, Maryam Sanati, Sukyung Lee, Yeon-Soo Kim, Sukchan Lee
  • Patent number: 8298566
    Abstract: The invention provides a bone material having a specific surface area of at least 80 m2/g and a protein content of less than 1800 ppm.
    Type: Grant
    Filed: October 19, 2006
    Date of Patent: October 30, 2012
    Inventor: Dimitrios Markoulides
  • Patent number: 8298822
    Abstract: Disclosed is a method for forming epithelial cells. Said method comprises the steps of aggregating stem cells from differentiated exocrine gland tissue to obtain an organoid body and differentiating at least one portion of the organoid body or a tissue body grown therefrom to obtain epithelial cells. Also disclosed is a cultivation device, particularly for forming differential epithelial cells.
    Type: Grant
    Filed: April 1, 2005
    Date of Patent: October 30, 2012
    Assignee: Fraunhofer-Gesellschaft zur Förderung der Angewandten Forschung E.V.
    Inventors: Charli Kruse, Gunter Fuhr, Thilo Wedel
  • Patent number: 8278053
    Abstract: Embodiments of the present disclosure provide for methods of studying (e.g., detecting, localizing, and/or quantifying) biomarker(s) and the like.
    Type: Grant
    Filed: May 18, 2009
    Date of Patent: October 2, 2012
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Gary M. Glazer, Samira Guccione, Sanjiv S. Gambhir, Aloma L. D'Souza
  • Patent number: 8278068
    Abstract: The present invention relates to the use of an ex vivo human skin sample as a biological model, particularly for the assessment of pharmacological and cosmetic effects.
    Type: Grant
    Filed: June 19, 2008
    Date of Patent: October 2, 2012
    Assignees: Symrise AG, Cutech SRL
    Inventors: Gabriele Vielhaber, Paolo Pertile
  • Patent number: 8273526
    Abstract: The present invention provides methods of cryopreserving stem and progenitor cells in a mammalian placenta; and methods of obtaining fetal stem and progenitor cells from a cryopreserved mammalian placenta. Cells obtained by carrying out the methods can be used in a variety of therapeutic applications.
    Type: Grant
    Filed: June 13, 2008
    Date of Patent: September 25, 2012
    Assignee: Children's Hospital & Research Center at Oakland
    Inventors: Frans A. Kuypers, Vladimir B. Serikov
  • Patent number: 8252560
    Abstract: The present invention relates to a process for producing a fatty acid, which includes feeding a liquid mixture formed of two liquid phases that flow in a co-current manner into a fixed bed-type reaction column packed with immobilized lipase, and performing a hydrolysis reaction when the two liquid phases are in contact with the immobilized lipase in the fixed-bed reaction column; wherein the fixed-bed reaction column comprises partition plates so as to comprise a plurality of tube- shaped structures, wherein each tube-shaped structure has a cross -section which is rectangular, circular, oval, or polygonal in shape with at least a part being unclosed and the cross-section has a representative length of 100 mm or less.
    Type: Grant
    Filed: December 14, 2007
    Date of Patent: August 28, 2012
    Assignee: Kao Corporation
    Inventors: Jun Saito, Yoshitaka Senda, Keigo Hanaki, Toshiteru Komatsu
  • Patent number: 8241672
    Abstract: A composition is provided which includes an enriched fish oil as a lipid source. Also provided is a composition which includes a fatty acid of a fish oil and a medium-chain triglyceride, wherein the composition is an oil-in-water emulsion.
    Type: Grant
    Filed: March 11, 2009
    Date of Patent: August 14, 2012
    Assignee: Stable Solutions LLC
    Inventor: David F. Driscoll
  • Patent number: 8227205
    Abstract: A method to detect live and dead cells in a sample with one bioluminogenic reagent is provided.
    Type: Grant
    Filed: April 10, 2008
    Date of Patent: July 24, 2012
    Assignee: Promega Corporation
    Inventor: Andrew Niles
  • Patent number: 8222015
    Abstract: A bioactive composition includes a hydrogel matrix. At least one protein is immobilized in the hydrogel matrix. The digestive protein has a half-life at least 1000 times longer than the half-life of a free digestive protein counterpart.
    Type: Grant
    Filed: May 9, 2008
    Date of Patent: July 17, 2012
    Assignees: Toyota Motor Engineering & Manufacturing North America, Inc., Toyota Motor Corporation, Regents of the University of Minnesota
    Inventors: Ping Wang, Songtao Wu, Hongfei Jia, Masahiko Ishii, Xiaodong Tong, Minjuan Zhang
  • Patent number: 8216817
    Abstract: The invention relates to an improved process of producing a fermentation product, such as ethanol, from starch-containing material using an increased dosage of alpha-amylase during liquefaction, which results in increased conversion of dextrins compared to conventional processes, and/or a reduced dosage of carbohydrate-generating enzyme during simultaneous saccharification and fermentation compared to a conventional process carried out at the same conditions. A process of the invention results in an increased yield. The invention also relates to an improved process of producing a fermentation product resulting in substantially the same yield as a conventional process, wherein reduced dosage of carbohydrate-source generating enzyme is used during simultaneous saccharification and fermentation.
    Type: Grant
    Filed: September 19, 2006
    Date of Patent: July 10, 2012
    Assignee: Novozymes North America, Inc.
    Inventors: George E. Gill, Billie Jean Savage, Swapnil Bhargava
  • Patent number: 8211677
    Abstract: A photocatalytic method for the hydroxylation of alkanes involving the use of a Cytochrome P450 class of enzyme as a catalyst which is activated by exposure to a pulsed blue light emitted from a light emitting diode (LED) at 450 nm±25 nm.
    Type: Grant
    Filed: October 19, 2010
    Date of Patent: July 3, 2012
    Assignee: Saudi Arabian Oil Company
    Inventor: Norman John Sheppard
  • Patent number: 8202514
    Abstract: A novel strain of Bacillus subtilis EB120 shows high antagonistic activity for controlling various plant diseases including barley powdery mildew, cucumber powdery mildew, red pepper anthracnose, rice blast, tomato gray mold, tomato late blight and wheat leaf rust, it can be effectively used as a microbioside for biologically controlling the plant diseases.
    Type: Grant
    Filed: March 23, 2005
    Date of Patent: June 19, 2012
    Assignee: Korea Research Institute of Chemical Technology
    Inventors: Kwang Yun Cho, Jin-Cheol Kim, Gyung Ja Choi, Seon-Woo Lee, Yong Ho Choi, Kyoung Soo Jang, He Kyoung Lim
  • Patent number: 8198058
    Abstract: The invention provides methods for producing methanol, higher alcohols (containing 2 or more carbons), in particular ethanol, or diesel fuel from biological wastes such as manure, sewage, and crop wastes, as well as from other organic materials. In the methods, organic material is first fermented by anaerobic microorganisms to a biogas consisting primarily of methane and carbon dioxide. The biogas is then converted to synthesis gas consisting primarily of CO and H2. The synthesis gas is then contacted with a liquid fuel production catalyst to synthesize higher alcohols or other liquid fuels. The invention involves converting CO2 in the biogas to synthesis gas by combining a CO2 reforming reaction with steam reforming or partial oxidation to convert the biogas to synthesis gas. The invention also provides methods involving recirculating CO2 from the output of the liquid fuel production reaction to one or more of the fermentation reaction, the CO2 reforming reaction, or the liquid fuel production reaction.
    Type: Grant
    Filed: March 5, 2008
    Date of Patent: June 12, 2012
    Inventor: John D. Offerman
  • Patent number: 8187852
    Abstract: A porous film is used as a cell culture substrate that is a scaffold for a spheroid. The porous film has a plurality of pores whose diameters gradually increase in a direction A. The diameters of the pores gradually increase from a first area P1 to a third area P3 in this order. The first to the third areas P1 to P3 are located on the porous film along the direction A. The diameters and depths of the pores increase in proportion to the distance in the direction A.
    Type: Grant
    Filed: March 26, 2009
    Date of Patent: May 29, 2012
    Assignee: FUJIFILM Corporation
    Inventors: Hidekazu Yamazaki, Tsukasa Ishihara
  • Patent number: 8187825
    Abstract: It is an object of the present invention to provide: a novel thiol-detecting reagent, which can be used in vivo and which solves the problem regarding the generation of background fluorescence due to hydrolysis; and a method for detecting thiol using the aforementioned reagent. The present invention provides a compound represented by the following formula (1): wherein each R2 independently represents an alkyl group containing 1 to 6 carbon atoms, a halogen atom, or a hydrogen atom.
    Type: Grant
    Filed: January 30, 2009
    Date of Patent: May 29, 2012
    Assignee: Riken
    Inventors: Hiroshi Abe, Yoshihiro Ito, Aya Shibata, Mika Ito