Patents Examined by Dwayne K. Handy
  • Patent number: 11965898
    Abstract: An automatic nucleic acid detection system and a method thereof are disclosed. The automatic nucleic acid detection method includes: performing, by an automatic control subsystem, on a nucleic acid extraction machine platform, a nucleic acid extraction on one or more specimens in a sample tray to generate one or more corresponding nucleic acids in the sample tray; distributing, by the automatic control subsystem, on a nucleic acid distribution machine platform, the nucleic acid in each hole of the sample tray and a first reagent into a plurality of holes of a detection tray, wherein the number of holes of the detection tray is greater than that of the sample tray; and performing, by the automatic control subsystem, on a nucleic acid detection machine platform, a nucleic acid detection on the detection tray.
    Type: Grant
    Filed: July 23, 2020
    Date of Patent: April 23, 2024
    Assignees: TCI GENE INC, TCI CO., LTD
    Inventors: Yung-Hsiang Lin, Cheng-Hong Hsieh, Ciao-Ting Chen, Tsung-Cheng Chen
  • Patent number: 11927576
    Abstract: A compact rock pyrolytic analysis and evaluation instrument comprises a sample introduction system, a pyrolytic furnace, a bypass system, a total hydrocarbon amount and methane content analysis system, a signal acquisition control system and a computer. The pyrolytic furnace is respectively connected with the sample introduction system and the bypass system, the total hydrocarbon amount and methane content analysis system is connected with the bypass system, the signal acquisition control system is used for controlling and connecting the total hydrocarbon amount and methane content analysis system, and meanwhile, the signal acquisition control system is communicated with the computer. The disclosure simultaneously detects the total amount of hydrocarbons produced by rock pyrolysis and the content of methane gas produced by rock pyrolysis, and the obtained data are reliable.
    Type: Grant
    Filed: October 13, 2020
    Date of Patent: March 12, 2024
    Inventors: Shujuan Kang, Rixiang Zhu
  • Patent number: 11927600
    Abstract: A fluidic bridge device for transport of a fluid sample between a first sample processing device and a second sample processing device. The fluidic bridge may include one or more fluid channels extending between fluid-tight couplings attachable to transfer ports of the first and second sample processing device. In one aspect the first device is a sample preparation device and the second device is an assay device. The fluidic bridge can include at least two fluid conduits, at least one for transport of the prepared sample, and at least one other to facilitate displacement of air to allow flow of the prepared sample through the other fluid conduit. The fluid channels can include one or more of an amplification chamber, a processing chamber, a gas-permeable vent, a bubble trap, a filter, and an external port. Methods of preparing and transporting a fluid sample between devices are provided herein.
    Type: Grant
    Filed: September 28, 2017
    Date of Patent: March 12, 2024
    Assignee: Cepheid
    Inventor: Douglas B. Dority
  • Patent number: 11904289
    Abstract: Systems, methods, and devices for generating radionuclides for use in production of radiopharmaceuticals; synthesizing the radionuclides generated and removing any unwanted products; measuring the quantity and activity level of the synthesized radionuclides; distributively delivering the radionuclides in appropriate quantities to modular cassette synthesis units in a modular cassette subsystem for contemporaneous/parallel production of radiopharmaceutical output and that allow reuse and/or quick, safe, and disposable replacement of portions of the subsystem; delivering non-radionuclide components to the modular cassette synthesis units as part of production of radiopharmaceutical output; measuring the quantity and activity level of each stream of radiopharmaceutical output; purifying the radiopharmaceutical output; dispensing individual doses in sterile vial(s); automatically producing labeling and dose related information; performing automated quality control on extracted samples of produced radiopharmaceuti
    Type: Grant
    Filed: December 22, 2020
    Date of Patent: February 20, 2024
    Assignee: Cardinal Health 414, LLC
    Inventors: Dennis Eshima, Mehmet Husnu, James Stone, Derrick Alcaide, Joseph E. Zambanini, Thomas A. Klausing, Chad E. Bouton, Henry Padgett, Brian C. Kelley, Scott N. Danhof, David A. Holley, Jeffrey T. Stroup, James B. Gleeson, Eric Hassenpflug, James A. Prescott, Herman Benecke, Daniel B. Garbark
  • Patent number: 11904321
    Abstract: A container includes a lower portion and a lid to connect with the lower portion. The lid includes a fluidic interface, a swing bar, and a counter structure disposed on an opposite side of the fluidic interface relative to the swing bar. The fluidic interface includes a first liquid port, a second liquid port, a gas port, and a seal ring disposed around the first liquid port, the second liquid port, and the gas port, the first liquid port disposed along a center axis of the container.
    Type: Grant
    Filed: May 28, 2020
    Date of Patent: February 20, 2024
    Assignee: LIFE TECHNOLOGIES CORPORATION
    Inventors: Mark Reed, Rui Zheng
  • Patent number: 11899033
    Abstract: The analyzer of the present invention is specifically adapted to provide moisture determinations for foods and other agricultural material. It allows the operator to introduce a precise weight of sample into a crucible in a closed furnace in a controlled environment through an access port in the furnace cover. The access port in the cover can be tapered to allow easy access to an underlying aligned crucible and allow an operator to add and remove sample material from the crucible until a precise desired sample weight is reached as measured by a balance within the furnace. The access port is enclosed by an insulated cover after the samples are sequentially placed in the crucibles.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: February 13, 2024
    Assignee: Leco Corporation
    Inventor: Larry S. O'Brien
  • Patent number: 11896975
    Abstract: The invention having functional vertical disposable reaction systems having a vertically mounted semipermeable membrane for sample preparation, chemical reactions, dialysis, enzymatic/microbiological fermentation, multistage processes, in vitro protein biosynthesis on a laboratory scale, formed from a base body and an exchangeable lid having different functions. For exchange across the membrane, the system is placed vertically into an outer volume consisting of gas, liquid or solid constituents. The system consists of a dimensionally stable base body and a liquid-tight lid having a functional support going toward the base of the base body, the dimensionally stable base body forming at least one noncapillary reaction space as inner volume with at least one semipermeable membrane as lateral wall. The high flexibility in use results from the combination of variants of the base bodies with different lid variants for different areas of use.
    Type: Grant
    Filed: January 30, 2019
    Date of Patent: February 13, 2024
    Assignee: Scienova GmbH
    Inventors: Stefan Kreusch, Thomas Richter, Raffael Rubick
  • Patent number: 11890613
    Abstract: The present invention relates to a recovery system for drops comprising: a conduit for the circulation of a working fluid comprising a plurality of pockets that are isolated by separators, a recovery substrate comprising multiple compartments, a displacement device that is able to successively position the outlet of the conduit opposite at least two different compartments, a preparation device that is able to inject, into the conduit, an additional volume of separator fluid and an additional volume of carrier fluid, such that the volume of at least one separator is greater than or equal to a critical separation volume, and that the volume of at least one bubble formed by a pocket and a part of the separator is greater than or equal to a critical detachment volume.
    Type: Grant
    Filed: January 4, 2018
    Date of Patent: February 6, 2024
    Assignee: GOLD STANDARD DIAGNOSTICS MILLIDROP
    Inventors: Laurent Boitard, Jairo Garnica Rodriguez
  • Patent number: 11891414
    Abstract: Sample plates and methods for exchanging buffer solutions are disclosed herein. The sample plates and methods may be used with automated buffer exchange systems where high pressures, for example, pressures of at least about 30 psig, are applied across a filtering membrane. Methods for manufacturing the sample plates are further disclosed.
    Type: Grant
    Filed: March 21, 2018
    Date of Patent: February 6, 2024
    Assignee: Unchained Labs
    Inventors: David Wesley Wyrick, Stuart Kazumi Morita, Lynn Comiskey, David Eugene Eberhart
  • Patent number: 11883817
    Abstract: A tube for sample collection and sample processing in a tube rack includes an upper section, an intermediate section, and a lower section. The intermediate section connects the upper section and the lower section of the tube, and an inner diameter of the intermediate section can decrease from top to bottom. A fastening means can fix the tube in a tube rack. The tube can include a pierceable tube cap sealing the tube, and the tube rack can be configured such that the tube may be pulled off the tube cap by a centrifugation force. The tube can include a volume of density gradient medium covered by a separating gel to enhance sample separation.
    Type: Grant
    Filed: January 25, 2017
    Date of Patent: January 30, 2024
    Inventor: Zhaoqiang Wang
  • Patent number: 11874288
    Abstract: A well plate includes a frame section that defines a plane, and a plurality of well structures. Each well structure extends in a direction away from the plane defined by the frame section, and each well structure defines a well for holding a fluid. The well plate further includes an artifact connected to at least one well structure. The artifact uniquely identifies a type of the well plate among other types of well plates. Along these lines, a result of a well plate type identification operation, which indicates whether the well plate includes the artifact, may determine whether a predefined pressure is applied to the well plate to facilitate fluid sampling in response to the result, whether fluid level sensing can be performed to gauge amounts of fluids drawn from the wells and/or identify how much fluid is left in the wells, etc.
    Type: Grant
    Filed: January 15, 2019
    Date of Patent: January 16, 2024
    Assignee: RedShift BioAnalytics Inc.
    Inventors: Charles McAlister Marshall, Richard C. Sharp, Frederick Milton Blodgett, Jr., Vlorent Morina, Jerry E. Hurst, Jr.
  • Patent number: 11857962
    Abstract: The present disclosure provides systems and methods for sample analysis. The system comprises a container. The container comprises a sample receptacle and a cap, and the cap comprises a reservoir for retaining a composition, a first piercing member and a first pierceable barrier for sealing said composition within said reservoir. There is also provided a method for sample analysis.
    Type: Grant
    Filed: August 2, 2022
    Date of Patent: January 2, 2024
    Assignee: APTITUDE MEDICAL SYSTEMS, INC.
    Inventors: Brian Scott Ferguson, Wentao Shi, Hui Kang, Tyler Chozinski, Jinpeng Wang, Qiang Gong
  • Patent number: 11814196
    Abstract: A pressure-tight storage vessel contains a liquid, has an elongated main body rotationally symmetrical with respect to an axis of symmetry, and forms, at least partially, a rotationally symmetrical hollow space in which the liquid is substantially received, wherein the main body is terminated at its bottom side by a base. Furthermore, at its top side, the storage vessel has an opening which is closed off in a pressure-tight manner by a closure, has a plurality of reinforcement elements, which bears against the main body at the outside, which extends parallel to the axis of symmetry of the main body, and arranged rotationally symmetrically about the axis of symmetry of the main body. In each case between adjacent reinforcement elements, respective externally exposed wall sections of the main body are formed, and the composition of the exposed wall sections permits a pressure-tight insertion by at least two hollow needles.
    Type: Grant
    Filed: December 18, 2019
    Date of Patent: November 14, 2023
    Assignee: EUROIMMUN Medizinische Labordiagnostika AG
    Inventors: Bianca Huth, Alexander Kowtun, Lars Koschinat, Frank Mollenhauer, Winfried Stoecker
  • Patent number: 11801507
    Abstract: The present invention is a cuvette assembly for use in optically measuring at least one characteristic of particles within a plurality of liquid samples. The cuvette assembly comprises a main body having internal walls and external walls, and a plurality of cuvettes within the main body at least partially being defined by the internal walls. Each of the plurality of cuvettes has a liquid-input chamber for receiving a respective one of the plurality of liquid samples, a filter, and an optical chamber for receiving a respective filtered liquid sample caused by passing the respective one of the plurality of liquid samples through the filter. Each of the optical chambers includes an entry window for allowing transmission of an input light beam through the filtered liquid sample and an exit window for transmitting a forward scatter signal caused by the particles within the filtered liquid sample.
    Type: Grant
    Filed: May 29, 2020
    Date of Patent: October 31, 2023
    Assignee: IP Specialists Ltd.
    Inventors: Dana A. Marshall, Theodore S. McMinn, Dan Vadim Regelman
  • Patent number: 11789007
    Abstract: The present invention provides a test barrel for placing a test paper card. The test barrel comprises a barrel body and a barrel lid; wherein the barrel body comprises a place reminding board arranged on the barrel body; and the barrel lid comprises an elastic piece arranged on the barrel lid and mating with the place reminding board. The test barrel for placing a test paper card according to the present invention is simple in structure and convenient in operation, and greatly reduces time for test. In addition, a place reminding structure is arranged on the test barrel, which facilitates use of the test barrel for the user and achieves sealing reminding. Further, the test result is accurate, the reusage rate is high, and cleaning is convenient.
    Type: Grant
    Filed: May 7, 2020
    Date of Patent: October 17, 2023
    Assignee: Zhejiang Orient Gene Biotech Co., Ltd.
    Inventor: Siyu Lei
  • Patent number: 11752501
    Abstract: A silicone member used for a micro device and a micro device which achieve both electrification suppression and light transmittance are provided. The silicone member is used as a micro device and has a holding part for holding samples, or defines the holding part through the combination with a counterpart member. The silicone member includes a silicone material which has silicone and an ionic conductive agent, and the content of the ionic conductive agent is 0.01 part by mass or higher and 1 part by mass or lower with respect to 100 parts by mass of the silicone. The micro device includes the silicone member.
    Type: Grant
    Filed: September 15, 2020
    Date of Patent: September 12, 2023
    Assignee: Sumitomo Riko Company Limited
    Inventors: Koji Morihara, Katsumi Okashita, Yasunori Nimura, Kazumi Yoshida
  • Patent number: 11738347
    Abstract: A liquid handling system and method, e.g., for testing blood samples. The system comprises a cartridge, and a transfer device couplable to a liquid reservoir. The cartridge comprises compartments with an inlet, closed by a seal, and an outlet, closed by a gas-permeable liquid-tight filter. Keying portions define a relative position and orientation of the cartridge and the transfer device. Penetrating elements of the transfer device penetrate the seal of each compartment, the penetrating elements having lumina for fluidly connecting the reservoir and each compartment cavity of the cartridge.
    Type: Grant
    Filed: August 24, 2018
    Date of Patent: August 29, 2023
    Assignee: INNATOSS LABORATORIES B.V.
    Inventors: Wolfram Julius Paul Peters, Michiel De Haan, Cornelia Maria De Jong, Freerk Van Oudheusden, Ingmar Christiaan Maurice, Marlies Van Dullemen, Antonius Franciscus Cornelia Maria Smetsers, Anja Garritsen
  • Patent number: 11731135
    Abstract: A specimen cap. The specimen cap allows material to be transferred out of a specimen cup without exposing the user (clinician, lab tech, phlebotomist) to the sample. The cap employs a double cap system with a secondary cap providing access to a needle holder that holds a needle assembly. The needle assembly has an upward extending needle, with an optional needle cover, and a downward extending draw or sample tube extending downward to reach the sample contained in the specimen cup.
    Type: Grant
    Filed: November 2, 2020
    Date of Patent: August 22, 2023
    Inventor: Marc Kopoian
  • Patent number: 11724261
    Abstract: A synthesizer system includes a vacuum block, a sealing plate coupled to the vacuum block, a synthesis plate having a plurality of wells, and an inflatable seal coupled to both the sealing plate and the synthesis plate and forming a seal between the sealing plate and the synthesis plate.
    Type: Grant
    Filed: May 12, 2020
    Date of Patent: August 15, 2023
    Assignee: INTEGRATED DNA TECHNOLOGIES, INC.
    Inventors: Robert West, Gregory Hodges, Justin Kline, Scott Steburg
  • Patent number: 11712697
    Abstract: A multi-well microtiter plate is provided designed for high-throughput screening of piercing-sucking arthropods,such as insects exposed to various compounds. The microtiter plates comprise a base comprising a plurality of sample wells, a covering made from pierceable material, a housing unit comprising a plurality of housing wells providing a predetermined fit in the plurality of sample wells, and an air-penetrable seal. Methods for containing, screening, and/or imaging piercing-sucking pests andarthropods utilizing the multi-chambered microtiter plates are also provided.
    Type: Grant
    Filed: November 20, 2018
    Date of Patent: August 1, 2023
    Assignee: BASF Agricultural Solutions Seed US LLC
    Inventors: Marion Ellis Driver, Justin Jeong Dailey