Patents Examined by Dwayne K. Handy
  • Patent number: 10888260
    Abstract: A biological fluid collection device that allows a blood sample to be collected anaerobically is disclosed.
    Type: Grant
    Filed: June 20, 2016
    Date of Patent: January 12, 2021
    Assignee: Becton, Dickinson and Company
    Inventors: Adam Edelhauser, Anthony V. Torris, Robert G. Ellis, Bradley M. Wilkinson, Joseph Nathan Pratt, Bartosz Marek Korec
  • Patent number: 10884008
    Abstract: Provided are: a device for storing biochemical reagents wherein an amount of a reagent can be hermetically stored and dropped from a storage site without coming into contact with the outside air; and a biochemical analyzer using the device. The device (10) is constituted by: sticking a top sheet (32) to a base sheet (31) provided with a convex-shaped hollow pocket (16) in which a reagent can be housed; a reagent container as a PTP packaging sheet (30) wherein an opening of the pocket in the base sheet (31), in which a reagent is preliminarily housed, is hermetically sealed with the top sheet (32); and sticking the film sheet surface as the top sheet (32) of the PTP packaging sheet (30), in which the reagent is hermetically packaged, to a cartridge surface of a device body (20) to thereby hermetically seal the inside of the device body too.
    Type: Grant
    Filed: April 27, 2015
    Date of Patent: January 5, 2021
    Inventors: Taro Nakazawa, Motohiro Yamazaki, Tatsuya Yamashita, Yoshitaka Kodama
  • Patent number: 10876936
    Abstract: A thermal system for controllably altering a temperature within a reaction chamber in a sample processing assembly is described. The reaction chamber is bounded by a substrate and cover member in the sample processing assembly. The thermal system includes at least one thermal generator for generating temperature changes, one or more transfer layers for transferring temperature changes between the thermal generator and the sample on the substrate and a fluid isolator for isolating the thermal generator from fluid dispensed into the reaction chamber.
    Type: Grant
    Filed: December 3, 2013
    Date of Patent: December 29, 2020
    Inventors: Peter Toogood, Kenneth Heng-Chong Ng, Anthony Favaloro, Stephen John Bagnato, Gregory William Boyes
  • Patent number: 10870109
    Abstract: A cup used to receive, hold, measure and pour liquids, such a specimens, such as for a medical assay, is described. The cup comprises an open receiving upper chamber, two or more open sample-directing channels, and an open, calibrated and marked measuring column. When sitting on a level surface, fluid flows freely from the upper chamber through the sample-directing channels into the measuring column. A foot is under each fluid-directing channel. The base of the measuring column functions as an additional, such as a third, foot. Cups nest, with the two feet of the upper cup sitting into two sample-directing columns of lower cup. The measuring column and upper chamber taper to permit nesting. If the cup is tipped, it rests on two of three of: the two feet and the base of the measuring column, and a point on a lower perimeter of the upper chamber, such that fluid will not spill.
    Type: Grant
    Filed: May 20, 2017
    Date of Patent: December 22, 2020
    Assignee: Sandstone Diagnostics, Inc.
    Inventors: Ulrich Schaff, Jon Epperson, Laura Fredriksen, Kirk Harmon
  • Patent number: 10871427
    Abstract: A biological liquid collection vessel is adapted to contain a biological liquid to be centrifuged. The collection vessel has a vessel body having an open upper end and a closed lower end, a continuous wall, a target area at the upper end, and a solids area at the lower end that is connected to the target area. The target area is extended in length. In some embodiments, a volume capacity of both of the target area and the solids area are configured so that a red blood cell portion of the centrifuged biological liquid (e.g., blood) is substantially contained in the solids area, and the serum or plasma portion of the centrifuged biological liquid is substantially contained in the target area. Methods of and systems using the liquid collection vessels are provided, as are other aspects.
    Type: Grant
    Filed: August 1, 2013
    Date of Patent: December 22, 2020
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Alex Hsu, Scott Salmon, Radu Saftoiu
  • Patent number: 10863736
    Abstract: An aliquoting and freezing storage device comprises a test tube and at least one capillary tube. The capillary tube is inserted into a test tube, and the capillary tube is provided with an inner long hole which penetrates throughly. The device utilizes the capillarity to quickly and easily store biological samples in the capillary tubes. When needed, the operator only needs to remove one or several of the tubes, without affecting the remaining biological samples, so as to avoid repeated freezing and thawing of biological samples.
    Type: Grant
    Filed: July 27, 2016
    Date of Patent: December 15, 2020
    Inventor: Xiaomin Cai
  • Patent number: 10866237
    Abstract: Disclosed is an ultrahigh-sensitivity two-dimensional chromatography-based biosensor, wherein cross-flow of high driving force across a narrow membrane is applied, thereby enabling the elimination of background noise, efficient supply of a large-sized polymeric or high-molecular-weight signal tracer, sequential material supply for increased reactivity, and simultaneous washing and signal generation when additional signal generation is required, as in an enzyme.
    Type: Grant
    Filed: January 26, 2017
    Date of Patent: December 15, 2020
    Assignee: Korea University Research and Business Foundation
    Inventor: Se-Hwan Paek
  • Patent number: 10850279
    Abstract: A bottom opening pod utilizing magnetic coupling for securing one or more cassettes within. The pod includes magnetic couplers that provide magnetic coupling between the cassette(s) and the bottom door of the pod. The magnetic couplers may include magnetic elements disposed on a base of the cassette and on the bottom door of the pod. The magnetic coupling secures the cassette(s) to the bottom door without imposition of separation forces between the housing and the bottom door of the pod.
    Type: Grant
    Filed: March 27, 2016
    Date of Patent: December 1, 2020
    Assignee: ENTEGRIS, INC.
    Inventor: Gregory Bores
  • Patent number: 10773849
    Abstract: A system (10) for removing a pipettable substance from a pre-filled container (20), which is closed off by a lid (30) having at least one opening area (40), comprises an opening tool (100) having a tube (110), which has a cross-section corresponding substantially to the shape of the opening area and which comprises at a distal end (120) an endpiece (140) extending substantially obliquely relative to the longitudinal axis of the tube, which moves a part of the lid (30) located inside the opening area (40) towards the container when the opening tool is applied, so as to form an opening in the lid, and a point of attack (150) for a transporting tool (200). The opening tool (100) is designed to remain on the container (20) after use.
    Type: Grant
    Filed: March 4, 2015
    Date of Patent: September 15, 2020
    Assignee: Qiagen GmbH
    Inventors: Thomas Voit, Andrea Wildhaber
  • Patent number: 10758901
    Abstract: An apparatus and a system for filtering a liquid sample in a sample well (310) by transferring the liquid out of the sample well (310) through a filter member (320) situated at a bottom part of the sample well (310). The apparatus and the system include a syringe (100), and a seal member (200) arranged around a nozzle (140) of the syringe (100) in such a way that the syringe (100) is adjustable in connection with an upper part of the sample well (310) in a substantially airtight manner. A method for filtering a liquid sample and use of the system for filtering eluted blood are also disclosed.
    Type: Grant
    Filed: September 1, 2009
    Date of Patent: September 1, 2020
    Assignee: WALLAC OY
    Inventors: Kauko Lehtinen, Jarmo Korpi
  • Patent number: 10744473
    Abstract: An ammonia oxidation catalyst basket design has two support grids. A first grid supports the primary catalyst and a separate, second grid supports the secondary catalyst. This dual grid design separates the two catalysts, and enables the catalysts to be independent of each other. Any interruption in the primary or the secondary catalyst does not impede or adversely impact on the structure or function of the other catalyst.
    Type: Grant
    Filed: August 17, 2015
    Date of Patent: August 18, 2020
    Inventor: F. Burke Allen
  • Patent number: 10737262
    Abstract: The invention relates to devices, methods and kits for separating biological materials, particularly populations of cells of different densities. The invention finds particular utility in the separation of blood into its different component parts or cellular populations. An insert for a centrifuge tube is disclosed that facilitates the effective separation of blood fractions by achieving a sharp and distinct interface between the density gradient medium and the blood sample. Methods and kits involving the use of the insert in separating cells are described.
    Type: Grant
    Filed: October 15, 2015
    Date of Patent: August 11, 2020
    Assignee: GE Healthcare US Limited
    Inventors: Michelle Louise Janas, Michael John Smith
  • Patent number: 10730071
    Abstract: A method for producing a plurality of measurement regions on a chip, and a chip having a plurality of measurement regions which is obtainable by the method.
    Type: Grant
    Filed: December 2, 2016
    Date of Patent: August 4, 2020
    Inventors: Axel Niemeyer, Heinz-Ulrich Schoeder, Matthias Griessner
  • Patent number: 10722893
    Abstract: A mounting and heating mechanism of sample collection containers for heating sample collection containers includes cup-shaped container heat transfer members for heating sample collection containers from the bottom surface and the side surface, a plate-like bottom surface member heated by a heater, frame members attached to an upper side of the bottom surface member and vertically movably storing the container heat transfer members, and sheet-like elastic heat transfer member disposed between the bottom surfaces of the container heat transfer members stored in the frame members and the upper surface of the bottom surface member.
    Type: Grant
    Filed: January 13, 2017
    Date of Patent: July 28, 2020
    Inventor: Tomoyuki Yamazaki
  • Patent number: 10722891
    Abstract: The present invention relates to a storage container for liquids, comprising a liquid-tight tank with an upwardly directed opening, wherein the opening is closed in a leaktight fashion by a protective film comprising an outer layer and an inner layer, wherein the outer layer is an aluminium foil and the inner layer is a plastic film, wherein the outer layer can be removed from the storage container separately from the inner layer, and wherein the inner layer can be pierced by a hollow needle; an assembly comprising at least two storage containers according to the invention; and a method for producing the assembly according to the invention, comprising the steps of providing at least two storage containers according to the invention, and applying a continuous layer of an adhesive film on the outer layers of the protective films of the at least two storage containers.
    Type: Grant
    Filed: December 1, 2015
    Date of Patent: July 28, 2020
    Inventor: Lars Koschinat
  • Patent number: 10703771
    Abstract: The present invention provides a new chemical process, a new cassette configuration, and new software for the automated production of multiple batches of an [18F]labelled compound on a single cassette. The invention allows one synthesizer in one hot cell to produce sequentially a plurality of batches of [18F]-labelled PET tracer in the same day. In particular, the present invention provides a novel arrangement useful for the trapping of [18F]fluoride and recovery of [18O]water.
    Type: Grant
    Filed: November 12, 2015
    Date of Patent: July 7, 2020
    Inventors: Xavier Franci, Steve Lignon, Audrey Marie Lange, Nicolas Verbrugge
  • Patent number: 10701961
    Abstract: An electric spraying device includes a spray emitter made of electrically conductive material, an electrode container made of electrically conductive material, and a voltage source. The electrode container has an opening at an upper end thereof, and the voltage source has a first pole electrically coupled to the spray emitter and a second pole electrically coupled to the electrode container. The spray emitter has an exit end disposed at or within the opening of the electrode container. The exit end of the spray emitter has a surface with a set of projections extending therefrom, and the set of projections are configured to form a concentrated electric field in response to an applied voltage from the voltage source between the first pole and the second pole. The spray emitter is constructed and arranged to conduct liquid along the surface to the set of projections, so as to polarize the liquid under the concentrated electric field and to dispense the liquid into the electrode container.
    Type: Grant
    Filed: October 21, 2016
    Date of Patent: July 7, 2020
    Inventors: Yixin Zhu, Tingting Lu, Linze Ge, Shengchun Wang
  • Patent number: 10694984
    Abstract: There is provided a test method for analysing a body fluid in which a test tape is used in a test device to successively provide analytical test fields stored on the test tape, wherein body fluid is applied by a user to the test field provided at a time and the said test field is photometrically scanned using a measuring unit of the device to record measurement signals. To increase the measurement reliability, it is proposed that a control value is determined from a time-dependent and/or wavelength-dependent change in the measurement signals and that the measurement signals are processed as valid or discarded as erroneous depending on the control value.
    Type: Grant
    Filed: February 18, 2019
    Date of Patent: June 30, 2020
    Assignee: Roche Diabetes Care, Inc.
    Inventors: Karl Miltner, Robert Lorenz, Ulrich Porsch, Clemens Knapp
  • Patent number: 10668466
    Abstract: The present invention is a cuvette assembly for use in optically measuring at least one characteristic of particles within a plurality of liquid samples. The cuvette assembly comprises a main body having internal walls and external walls, and a plurality of cuvettes within the main body at least partially being defined by the internal walls. Each of the plurality of cuvettes has a liquid-input chamber for receiving a respective one of the plurality of liquid samples, a filter, and an optical chamber for receiving a respective filtered liquid sample caused by passing the respective one of the plurality of liquid samples through the filter. Each of the optical chambers includes an entry window for allowing transmission of an input light beam through the filtered liquid sample and an exit window for transmitting a forward scatter signal caused by the particles within the filtered liquid sample.
    Type: Grant
    Filed: July 31, 2018
    Date of Patent: June 2, 2020
    Inventors: Dana A. Marshall, Theodore S. McMinn, Dan Vadim Regelman
  • Patent number: 10668471
    Abstract: The present invention provides microfabricated substrates and methods of conducting reactions within these substrates. The reactions occur in plugs transported in the flow of a carrier-fluid.
    Type: Grant
    Filed: August 10, 2017
    Date of Patent: June 2, 2020
    Assignee: The University of Chicago
    Inventors: Rustem F. Ismagilov, Joshua David Tice, Helen Song Baca, Lewis Spencer Roach