Patents Examined by Elizabeth Weimar
  • Process for preparation of propionic acid
    Patent number: 4732855
    Abstract: An improved process for the production of propionic acid comprises cultivating a propionic acid-producing bacterium anaerobically in a medium which contains a simple carbohydrate, which can be converted by the bacterium to pyruvate, as well as essential minerals, vitamins, and growth factors under an overpressure of hydrogen which is effective to cause a hydrogenase produced by the bacterium to suppress the oxidation of pyruvate to acetate and carbon dioxide and to promote the formation of propionic acid.
    Type: Grant
    Filed: April 3, 1984
    Date of Patent: March 22, 1988
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Joseph G. Zeikus, Thomas E. Thompson
  • Method of producing reverse transcriptase
    Patent number: 4729955
    Abstract: A method of producing reverse transcriptase, which comprises isolating a fraction containing retrovirus from a tissue culture fluid supernatant of retrovirus producing cells which are able to grow and propagate in vitro, treating said fraction at least once by sucrose density gradient centrifugation to thereby obtain a purified retrovirus, and extracting reverse transcriptase from said purified retrovirus.
    Type: Grant
    Filed: December 8, 1983
    Date of Patent: March 8, 1988
    Assignee: Director of The National Institute of Animal Health
    Inventors: Michi Kodama, Kiichi Sekiguchi, Masanori Kubo
  • Process of stabilizing aspartame sweetness in water-containing foods
    Patent number: 4722844
    Abstract: A sweetening agent or sweetened food which comprises .alpha.-L-aspartyl-L-phenylalanine methyl ester (Aspartame) and an aqueous dispersing agent, wherein the Aspartame is present in an amount sufficient to saturate the aqueous dispersing agent and further to provide undissolved Aspartame, is disclosed along with a method for producing such foods and sweetening agents.
    Type: Grant
    Filed: August 28, 1985
    Date of Patent: February 2, 1988
    Assignee: Ajinomoto Co., Inc.
    Inventors: Toshiyuki Ozawa, Hideki Hattori
  • Heat stabilized sweetener composition containing APM
    Patent number: 4704288
    Abstract: This invention encompasses a heat stabilized composition of aspartame, its salts or metal complexes and a partially hydrogenated vegetable oil melting at about 120.degree. F. or above. This composition is particularly useful in baking applications for aspartame.
    Type: Grant
    Filed: December 19, 1986
    Date of Patent: November 3, 1987
    Inventors: Josef H. Tsau, James G. Young
  • Method for isolating product-producing cells
    Patent number: 4659655
    Abstract: The invention relates to techniques for isolating from a mixed population of cells disired living cells either producing and releasing a particular product or having a characteristic molecule on their surface. The isolation techniques depend upon the localized interaction between the product (or molecule) and other agents added to the system such that distinguishable conditions can be caused to occur (or not occur) only in the immediate vicinity of desired cells which produced and released the product or which contain the molecule on their surface.
    Type: Grant
    Filed: November 23, 1982
    Date of Patent: April 21, 1987
    Assignee: Bio-Response, Inc.
    Inventor: Sam Rose