Patents Examined by Emily L Schmidt
  • Patent number: 10980949
    Abstract: A cap assembly for a medicament delivery device is disclosed. The cap assembly includes a cap configured to be mounted to a proximal end of the medicament delivery device, wherein the cap comprises a cam surface. The cap assembly further includes a squeezer comprising (i) a body defining a first longitudinally extending channel configured to receive a delivery member shield and (ii) a plurality of radial arms flexible in a radial direction. The cap assembly also includes a spinner comprising (i) a proximal end face configured to cooperate with the cam surface of the cap, (ii) a body defining a second longitudinally extending channel configured to receive the squeezer, and (iii) a plurality of holes in the body of the spinner configured to receive the plurality of radial arms of the squeezer.
    Type: Grant
    Filed: December 26, 2018
    Date of Patent: April 20, 2021
    Assignee: SHL MEDICAL AG
    Inventor: Brian Maxfield
  • Patent number: 10980992
    Abstract: Disclosed herein are microneedle devices, kits comprising the microneedle devices, and methods of using the microneedle devices. Specifically, disclosed is a device for transport of a material across a biological barrier of a subject comprising: a plurality of microneedles each having a base end and a tip, with at least one pathway disposed at or between the base end and the tip; a substrate to which the base ends of the microneedles are attached or integrated; and at least one reservoir which is in connection with the base ends of the microneedles array, wherein the reservoir comprises an agent delivery system, wherein the agent delivery system comprises an agent to be transported across the biological barrier, or a means for producing an agent to be transported across the biological barrier, and a means for detecting a physiological signal from the recipient.
    Type: Grant
    Filed: February 17, 2017
    Date of Patent: April 20, 2021
    Assignee: North Carolina State University
    Inventors: Zhen Gu, Yanqi Ye
  • Patent number: 10973539
    Abstract: The present disclosure relates to a basket for a catheter designed to be deployed in complex vasculature to optimally treat vascular and arterial disease conditions such as blood clots, blood emboli, and deep vein thrombosis. The basket may comprise a shaft with a plurality of cuts along a portion of its length to form a plurality of tines that provide support for a plurality of porous tubes to form the limbs of the basket. The limbs of the basket expand radially away from the longitudinal axis of the basket when the longitudinal length of the basket is reduced. The limbs may also be connected to a drug delivery system, and in this manner, baskets of the present disclosure allow for the use of both mechanical and pharmaceutical means of thrombolysis.
    Type: Grant
    Filed: October 19, 2018
    Date of Patent: April 13, 2021
    Assignee: THROMBOLEX, INC.
    Inventor: Nicholas Green
  • Patent number: 10960146
    Abstract: A drug delivery device includes an inner body adapted to receive a pre-filled syringe with an injection needle, one or more flexible arms on the inner body extending in a distal direction, and one or more support members slidably arranged to operatively outwardly support the flexible arms. The flexible arms have respective inwardly directed protrusions adapted to engage a neck of the syringe. When the support member is in a distal position, it does not support the flexible arms. When the support member is in a proximal position, the support member supports the flexible arms and prevents them from being outwardly deflected.
    Type: Grant
    Filed: July 12, 2017
    Date of Patent: March 30, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventor: Michael Helmer
  • Patent number: 10960155
    Abstract: An apparatus includes a label configured to be coupled to a medicament delivery device. The label includes a first surface and a second surface. The first surface is configured to be coupled to an outer surface of the medicament delivery device. The second surface includes a textual indicia. The label further includes an electronic circuit system configured to output an electronic signal.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: March 30, 2021
    Assignee: kaleo, Inc.
    Inventors: Eric S. Edwards, Evan T. Edwards, Mark J. Licata, Paul F. Meyers, David A. Weinzierl
  • Patent number: 10953159
    Abstract: A cannula comprising a hollow tube made of a biocompatible, thermoplastic polymer, memory shape material, tipped with an injection needle at it distal end, assumes desired shapes as it distally emerges from a lumen or channel of an instrument such as an introducer or endoscope. The desires shape includes a curvature conforming to an inverse tangent function. The cannula may be supplied alone, with or without an injection needle, and in a sterile pouch, for use with a device of an user's choice that has a suitable lumen or channel to guide the cannula, of the cannula may be used without such an instrument.
    Type: Grant
    Filed: September 9, 2019
    Date of Patent: March 23, 2021
    Assignee: URO-1, Inc.
    Inventors: Phillip Jack Snoke, Philip Morrison Allred, III, John Joseph Smith, Ted Belleza
  • Patent number: 10946182
    Abstract: A subcutaneous vein access port implanted into a living body to be connected to a subcutaneous vein, includes: a housing formed therein with a receiving portion to which a medicine is supplied; a cover membrane disposed at an upper end of the housing and sealing an upper side of the receiving portion; a conduit provided to the housing and inserted into the subcutaneous vein to connect the subcutaneous vein to the receiving portion; and a light source emitting light such that the light from the light source is discharged outside through the cover membrane.
    Type: Grant
    Filed: March 5, 2018
    Date of Patent: March 16, 2021
    Assignee: MEDI TULIP CO., LTD.
    Inventor: Min Woong Kang
  • Patent number: 10933216
    Abstract: An intravascular device delivery system includes an elongated member with a proximal end, a distal end, and a longitudinal axis therebetween. The elongated member includes a multilumen catheter having a catheter wall with a plurality of lumen in the catheter wall. The plurality of lumen extends from a proximal end of the elongated member to a distal end of the elongated member. A lumen ratio of the cross-sectional area of the plurality of lumen and the cross sectional area of the catheter wall is greater than 30%.
    Type: Grant
    Filed: July 27, 2017
    Date of Patent: March 2, 2021
    Assignee: CEPHEA VALVE TECHNOLOGIES, INC.
    Inventors: Randolf von Oepen, Sean A. McNiven, Francisco Valencia
  • Patent number: 10933195
    Abstract: A syringe having a mechanical ejection mechanism. The ejection mechanism includes an actuator and a rotational gear. The actuator has a retractable pawl configured to engage the gear when the actuator is displaced from a non-depressed position into a depressed position. Displacement of the actuator causes the gear to rotate by a predetermined angle. The rotation of the gear is translated into linear displacement of the plunger within the barrel, thereby ejecting a predetermined amount of solution from the barrel.
    Type: Grant
    Filed: January 21, 2019
    Date of Patent: March 2, 2021
    Inventors: Andriy Lytvyn, Irina M. Lytvyn
  • Patent number: 10926061
    Abstract: An innovative medical device that permits rapid, minimally invasive restoration of blood flow across a vascular blockage. A system allowing for lysis or removal of said blockage. Said device creates a temporary bypass using longitudinal structure configured for insertion into the blood vessel and adapted to deliver a side hole to a target area. The side hole defines a distal first segment and a proximal second segment with a lumen to allow blood flow therethrough to at least one distal end hole. Said device includes at least one semi-permeable membrane which may act as a filter that located circumferentially around outer surface of at least one of said device segments. In an alternate embodiment, a slidable outer sheath can cover the side hole to permit reversal of blood flow from the distal end hole to a proximal end hole located outside a patient's body by means of an aspiration controller.
    Type: Grant
    Filed: February 5, 2018
    Date of Patent: February 23, 2021
    Inventor: Daniel Ezra Walzman
  • Patent number: 10926036
    Abstract: One embodiment is directed to a system for injecting, comprising a syringe body defining an interior medicine chamber; a stopper member configured to be inserted into the interior medicine chamber to contain medicine within the medicine chamber; a plunger member configured to be manually manipulated to insert the stopper member relative to the syringe body; and a needle having proximal and distal ends, the proximal end comprising an anchoring geometry configured to be at least partially inserted into the stopper member such that upon retraction of the stopper member, the needle is pulled proximally along with the stopper to be at least partially contained within the interior medicine chamber.
    Type: Grant
    Filed: December 27, 2018
    Date of Patent: February 23, 2021
    Assignee: Credence Medsystems, Inc.
    Inventors: Alan E. Shluzas, Stephen H. Diaz, John F. Shanley, Jeff Tillack, Dan Thayer, Gary Steese-Bradley
  • Patent number: 10918798
    Abstract: A medicament injection device includes a main body configured to receive a medicament cartridge sealed by a penetrable barrier, a cap assembly having an inner needle part and an outer needle part, wherein the inner needle part is movable in a proximal direction with respect to the outer needle part, a needle carrier carrying a needle, the needle carrier being releasably coupled to the inner needle part, wherein, when the inner needle part is displaced in the proximal direction, the inner needle part causes the needle carrier to be displaced axially in the proximal direction, and wherein, subsequent to the axial displacement of the inner needle part, the cap assembly is separable from the main body by movement of the cap assembly in a distal direction.
    Type: Grant
    Filed: November 21, 2016
    Date of Patent: February 16, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventor: Michael Helmer
  • Patent number: 10912923
    Abstract: A catheter assembly includes an inner liner made of flexible material and an outer layer having a steering mechanism. The steering mechanism includes at least one flat wire and a corresponding lumen through which the flat wire may travel. The steering mechanism may also include at least one pull ring to which the flat wires are attached. A layer of heat shrink material may encompass the outer layer. A braided wire assembly may also be provided in the outer layer, and may be formed by braiding a plurality of flat wires into a wire mesh. The overall cross-section of the catheter assembly is preferably substantially circular. A catheter shaft may include a plurality of segments of differing hardness characteristics. The outer layer typically comprises a melt processing polymer such that the catheter assembly may be laminated using heat.
    Type: Grant
    Filed: October 4, 2018
    Date of Patent: February 9, 2021
    Assignee: St. Jude Medical, Atrial Fibrillation Division, Inc.
    Inventors: Wayne Heideman, Allan M. Fuentes, Richard E. Stehr, Sarah Cumming, Mark Dustrude
  • Patent number: 10912584
    Abstract: A trocar seal membrane with multi-dimensional pleats. The seal membrane includes a proximal opening, a distal aperture, and a sealing wall from the distal aperture ex-tending to the proximal opening, the sealing wall includes a proximal surface and a distal surface. The distal aperture formed by a sealing lip for accommodating the inserted instrument forms a gas-tight seal. In the lip-adjacent area, the sealing wall simultaneously has a plurality of transverse pleats extending laterally outwardly from the sealing lip and a plurality of tangential pleats uniformly distributed around the sealing lip. The pleated sealing wall can enlarge hoop circumference in the lip-adjacent area, and reduce overall deformation when a large-diameter instrument is inserted, thereby reducing friction and improving sealing reliability.
    Type: Grant
    Filed: January 16, 2019
    Date of Patent: February 9, 2021
    Inventor: Moshu Zhu
  • Patent number: 10898658
    Abstract: An injection device uses telescoping and/or nested components and other features to make the overall device compact in size. The device is configured to have a storage position and an extended position, such that its needle is positioned within the housing of the device in a storage position, with the needle extending beyond the device housing when needed for an injection. The telescoping plunger mechanism has a storage position and an extended position for use. The device includes a needle depth cover, which extends from the device housing for use, and guides the user as to the correct depth for the needle to penetrate the user's skin. A switch allows different depth settings, for example allowing a deeper penetration for injection into a leg, and shallower penetration for injection into an arm.
    Type: Grant
    Filed: July 5, 2017
    Date of Patent: January 26, 2021
    Assignee: LynJohnston, LLC
    Inventors: Linda J. Waller, Paul Henninge
  • Patent number: 10888688
    Abstract: An insertion device for delivering media inside a patient includes an outer guide tube having a side port. An inner guide tube is nested within the outer guide tube and movable axially within the outer guide tube. The inner guide tube includes a deflector at an end within the outer guide tube. The device also includes a catheter nested within the inner guide tube and movable axially within the inner guide tube. The deflector of the inner guide tube is positionable such that it deflects the dispensing end of the catheter outward through the opening in the outer guide tube when the catheter is advanced axially within the inner guide tube. A therapeutic delivery cannula may be nested within the catheter, such that the deflected end of the catheter determines the direction of travel of the therapeutic delivery cannula into patient tissue when the cannula emerges from the catheter.
    Type: Grant
    Filed: October 1, 2018
    Date of Patent: January 12, 2021
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Daniel A. Lim, Matthew Silvestrini, Tejal Desai
  • Patent number: 10864330
    Abstract: A system for mixing drug products and injecting includes a syringe body, proximal and distal stopper members disposed in the syringe body, a plunger member, and a needle hub assembly coupled to the distal needle interface of the syringe body. The proximal and distal stopper members form a proximal drug chamber between there between and a distal drug chamber between the distal stopper member and a distal end of the syringe body. The plunger member includes a needle retention feature, an energy-storage member, and an energy-storage member latching member all disposed in disposed in a plunger interior. First and second sizes of the respective proximal and distal drug chambers can be modified by movement of the proximal and distal stopper members relative to the syringe body. The needle is at least partially retractable into plunger interior upon manipulation of the plunger member relative to the syringe body.
    Type: Grant
    Filed: November 1, 2017
    Date of Patent: December 15, 2020
    Assignee: CREDENCE MEDSYSTEMS, INC.
    Inventors: Gary Steese-Bradley, Stephen H. Diaz, Alan E. Shluzas, John F. Shanley, Jeff Tillack, Dan Thayer, John Merhige
  • Patent number: 10857328
    Abstract: An innovative medical device that permits rapid, minimally invasive restoration of blood flow across a vascular blockage. A system allowing for lysis or removal of said blockage. Said device creates a temporary bypass using longitudinal structure configured for insertion into the blood vessel and adapted to deliver a side hole to a target area. The side hole defines a distal first segment and a proximal second segment with a lumen to allow blood flow therethrough to the distal end hole. In an alternate embodiment, a slidable outer sheath can cover the side hole to permit reversal of blood flow from the distal end hole to a proximal end hole located outside a patient's body by means of an aspiration controller. Alternate embodiments include an optional anchoring balloon, a macerating stent or wires, perforations for fluid delivery, and an backflow valve.
    Type: Grant
    Filed: January 16, 2018
    Date of Patent: December 8, 2020
    Inventor: Daniel Ezra Walzman
  • Patent number: 10849658
    Abstract: Disclosed is a seal membrane and assembly including the concave-channel. The seal membrane includes a proximal opening, a distal aperture, and a sealing wall from the distal aperture extending to the proximal opening. The sealing wall includes a proximal surface and a distal surface. The distal aperture is formed by a sealing lip for accommodating the inserted instrument and forming a gas-tight seal. The sealing wall includes a main rotary-wall and multiple concave-channels.
    Type: Grant
    Filed: January 9, 2019
    Date of Patent: December 1, 2020
    Inventor: Moshu Zhu
  • Patent number: 10849655
    Abstract: Disclosed is a trocar seal membrane and assembly including normal concave-channels and reverse concave-channels. The seal membrane includes a proximal opening, a distal aperture, and a sealing wall from the distal aperture extending to the proximal opening. The distal aperture formed by a sealing lip for accommodating the inserted instrument forms a gas-tight seal. The sealing wall includes a proximal surface and a distal surface. The sealing wall is a seamless sealing body with multiple normal concave-channels and multiple reverse concave-channels surrounding the sealing lip in an alternating manner. The normal concave-channels and reverse concave-channels has the functions of enlarging hoop circumference, reducing the wrapped-area, improving lubrication reliability, increasing the axial tensile stiffness, etc., thereby, the frictional resistance and the stick-slip can be greatly reduced.
    Type: Grant
    Filed: January 9, 2019
    Date of Patent: December 1, 2020
    Inventor: Moshu Zhu