Abstract: Aspects relate to a portable device that may be used to identify a critical intensity and an anaerobic work capacity of an individual. The device may utilize muscle oxygen sensor data, speed data, or power data. The device may utilize data from multiple exercise sessions, or may utilize data from a single exercise session. The device may additionally estimate a critical intensity from a previous race time input from a user.

Abstract: The present disclosure provides methods and apparatus for evaluating the flow of blood in damaged or healing tissue. The present disclosure also provides methods of identifying a patient at the onset of risk of pressure ulcer or at risk of the onset of pressure ulcer, and treating the patient with anatomy-specific clinical intervention selected based on perfusion or blood oxygenation values, or a combination thereof. The present disclosure also provides methods of stratifying groups of patients based on risk of wound development and methods of reducing incidence of tissue damage in a care facility. The present disclosure also provides methods to analyze trends of perfusion or oxygenation measurements to detect tissue damage before it is visible, and methods to compare bisymmetric perfusion values to identify damaged tissue.

Abstract: A measurement engine of a wearable electronic device may compensate for wavelength variations of light emitted as part of blood-oxygen saturation measurements. In some cases, determining an estimated blood-oxygen saturation value is based at least partially on temperature data that may be used to compensate for temperature-based wavelength variations of the emitted light, drive current data that may be used to compensate for drive-current-based wavelength variations of the emitted light, and/or calibration information that may be used to compensate for manufacturing variability across different light emitters. In various embodiments, the measurement engine may use temperature data, the drive current data, and/or calibration information in a variety of ways to determine estimated blood-oxygen saturation values, including using lookup tables or calibration curves, applying functions, and the like.

Abstract: A wearable electronic device may include a display and a housing. The housing may include a chassis defining a first portion of a rear exterior surface of the wearable electronic device, a first portion of a side exterior surface of the wearable electronic device, and an internal wall. The housing may also include a glass shell defining a front wall positioned over the display and defining a front exterior surface of the wearable electronic device and a side wall extending from the front wall and overlapping the internal wall, the side wall defining a second portion of the side exterior surface of the wearable electronic device. The wearable electronic device may also include a touch sensing system within the housing and configured to detect a touch input applied to the front exterior surface of the wearable electronic device.

Abstract: Estimation of a characteristic of a user's physiological signals can be improved using one or more calibration relationships that may be dependent on a characteristic of the optical sensor. For example, different calibration relationships can be used that are dependent on a spatial characteristic and/or that are dependent on a wavelength characteristic of the light emitting component(s) of the respective emitter of a channel. In some examples, a unique calibration relationship can be used for each channel. In some examples, a common calibration relationship can be used for multiple channels with shared distance and/or wavelength characteristics. Utilizing distance-dependent and/or wavelength-dependent calibration relationships can improve robustness of pulse oximetry measurements.

Abstract: A physiological signal monitoring device includes a base including a base body that has a bottom plate and an opening, a biosensor mounted to the base, and a transmitter removably mounted to the base body. The base further includes a first coupling structure disposed on a top surface of the bottom plate, and the transmitter includes a second coupling structure coupled to the first coupling structure when the transmitter is mounted to the base body. When the first and second coupling structures are coupled to each other, they are disposed to be distal from a periphery cooperatively defined by the base and the transmitter. They are uncoupled from each other when an external force is applied through the opening of the base body to separate the transmitter from the base.

Abstract: A device, a substrate including a connection port. The substrate includes traces to enable a circuit of the substrate. The circuit is connected to the connection port. A light sensor mechanically and electrically attached respectfully to a first planar surface of the substrate and the circuit. A light source is mechanically and electrically attached respectively to the first planar surface and the circuit. The light source is located lateral to the light sensor at a first distance. A light signal of the light source emanates from the light source at an angle perpendicular to the first planar surface and a reflector mechanically attached to the first planar surface and located between the light sensor and the light source. The light signal is substantially reflected by the reflector away from the light sensor.

Abstract: An active-pulse blood analysis system has an optical sensor that illuminates a tissue site with multiple wavelengths of optical radiation and outputs sensor signals responsive to the optical radiation after attenuation by pulsatile blood flow within the tissue site. A monitor communicates with the sensor signals and is responsive to arterial pulses within a first bandwidth and active pulses within a second bandwidth so as to generate arterial pulse ratios and active pulse ratios according to the wavelengths. An arterial calibration curve relates the arterial pulse ratios to a first arterial oxygen saturation value and an active pulse calibration curve relates the active pulse ratios to a second arterial oxygen saturation value. Decision logic outputs one of the first and second arterial oxygen saturation values based upon perfusion and signal quality.

Abstract: Systems and methods are disclosed in which changes in the position and/or orientation of an anatomical structure or of a surgical tool can be measured quantitatively during surgery. In some embodiments, the systems and methods disclosed herein can make use of inertial motion sensors to determine a position or orientation of an instrument or anatomy at different times and to calculate changes between different positions or orientations. In other embodiments, such sensors can be utilized in conjunction with imaging devices to correlate sensor position with anatomical landmarks, thereby permitting determination of absolute angular orientation of a landmark. Such systems and methods can facilitate real-time tracking of progress during a variety of procedures, including, e.g., spinal deformity correction, etc.

Abstract: A physiological monitor is provided for determining a physiological parameter of a medical patient with a multi-stage sensor assembly. The monitor includes a signal processor configured to receive a signal indicative of a physiological parameter of a medical patient from a multi-stage sensor assembly. The multi-stage sensor assembly is configured to be attached to the physiological monitor and the medical patient. The monitor of certain embodiments also includes an information element query module configured to obtain calibration information from an information element provided in a plurality of stages of the multi-stage sensor assembly. In some embodiments, the signal processor is configured to determine the physiological parameter of the medical patient based upon said signal and said calibration information.

Abstract: A system with an analyzer device in fluid communication with a sample of a bodily fluid is configured to chemically or electrochemically convert at least a portion of ammonium (NH4+) contained within the bodily fluid into ammonia (NH3) and dispel the converted ammonia (NH3) into a gas sensing chamber. An ammonia (NH3) sensor located within the gas sensing chamber in conjunction with a processor can quantify an amount of ammonia (NH3) present in the gas sensing chamber in relation to the total ammonia of the bodily fluid.

Abstract: A guidewire formed from drawn filled tubing having an inner core member encased in an outer layer. The inner core member is formed from a linear elastic or superelastic material and the outer layer is formed from a metal alloy such as 35N LT. A portion of the outer layer is ground down to form a feather edged joint between the outer layer and the inner core member.

Abstract: A robust alarm system has an alarm controller adapted to input an alarm trigger and to generate at least one alarm drive signal in response. Alarm subsystems input the alarm drive signal and activate one or more of multiple alarms accordingly. A subsystem function signal provides feedback to the alarm controller as to alarm subsystem integrity. A malfunction indicator is output from the alarm controller in response to a failure within the alarm subsystems.

Abstract: Instrumented mouthguards include components such as accelerometer modules that enable monitoring of head movements of a mouthguard wearer. Various embodiments that provide instrumented mouthguard devices and components configured for use in instrumented mouthguard devices, including flexible circuit board substrates. In some embodiments, the flexible circuit board substrate is configured to allow sizing irregularities resultant from customization of the mouthguard body to a specific wearer.

Abstract: A blood pressure measurement device includes: a case including; a strap; a plurality of valves; a pump; and a power supply unit. The pump and the power supply unit are disposed with a gap therebetween. The pump is provided with a suction hole on a surface thereof opposite to the power supply unit. The device comprises a hole portion formed between each of a pairs of lugs of an outer case, an opening end being located at a position opposed to the gap in a first direction. The hole portion extends linearly, and one opening end of the hold portion is provided on the outer surface of the outer case closer to a wrist, and other opening end thereof is provided on the inner surface of the outer case closer to a windshield than the one opening end.

Abstract: The invention provides a controller and method for deriving a measure of arterial compliance based on an acquired arterial volume variation signal and an acquired pulse arrival time signal. An oscillometric blood pressure measurement device is used to acquire the arterial volume variation signal. Arterial volume and variation in pulse arrival time are both measured as an applied pressure to an artery are varied by the oscillometric blood pressure measurement device. The arterial volume signal is transformed into a corresponding signal representative of variation in peak-to-peak amplitude of the arterial volume.

Abstract: An electronic valve with: a yoke including an end plate portion and a side plate portion; a pole piece; a solenoid coil; and a diaphragm made of a plate-shaped magnetic material. The pole piece has an opening at one end portion and a first fluid inlet/outlet communicating with the opening at the other end portion. A biasing unit biases the diaphragm in a direction away from one end portion of the pole piece in a manner of moving the diaphragm translationally in one direction. In a non-operating time, the electronic valve comes into an open state where the opening is open. In an operating time, the diaphragm approaches the one end portion of the pole piece against the biasing force of the biasing unit by a magnetic force generated by the solenoid coil, and the electronic valve can come into a closed state where the opening is closed.

Abstract: Systems, methods and apparatus are provided for determining an estimate of an analyte level over time. The invention includes sampling sensor data using an analyte sensor positioned at least partially subcutaneously; storing a plurality of datasets of sensor data, each at a different rate; determining an estimated analyte level based on the datasets; and outputting the estimated analyte level to a display. Numerous additional aspects are disclosed.

Abstract: The present invention relates to a body attachment unit for continuous glucose monitoring.

Abstract: In some examples, a medical system includes a medical device. The medical device may include a housing configured to be implanted in a target site of a patient, a light emitter configured to emit a signal configured to cause a fluorescent marker to emit a fluoresced signal into the target site, and a light detector that may be configured to detect the fluoresced signal. The medical system may include processing circuitry configured to determine a characteristic of the fluorescent marker based on the emitted signal and the fluoresced signal. The characteristic of the fluorescent marker may be indicative of a presence of a compound in the patient, and the processing circuitry may be configured to track the presence of the compound of the patient based on the characteristic of the fluorescent marker.