Abstract: Data about concentration of one or more types of molecules present within a human body are determined noninvasively using radio frequency signals. These signals generated at very low power levels are emitted and acquired using an antenna mounted to a wearable device. Information about changes to the signals is indicative of the concentration of one or more types of molecules within the user. The antenna includes two or more elements with a varying distance between them which reduces or eliminates power reflection and improves overall efficiency. The varying distance provides a first impedance at terminals of the antenna and a second impedance elsewhere on the antenna, such as midway along a long axis of the antenna. The first impedance matches an impedance of a transmitter output, a receiver input, or both. The second impedance results in the signal extending away from the antenna towards the user.

Abstract: Systems, devices, and methods are described herein for ensuring constant contact of a physiological sensor with a subject. A device may include a wearable band wearable by the subject, an elastic coupling member, a sensor module coupled by the elastic coupling member to the wearable band, a housing attached to the wearable band, a processor, and a user interface. The wearable band may include a recess extending into the wearable band. The elastic coupling member and/or the sensor module may be disposed within the recess. As the subject wears the wearable band, the elastic coupling member may press the sensor module against the subject and may cause constant contact between the sensor module and the subject. Electrical tracing embedded in the wearable band and extending from the sensor module to the housing may couple the sensor module to the processor or the user interface.

Abstract: An apparatus for measuring foot blood flow has a platform with a platform contact surface configured to receive a foot force from a user placing their foot on the contact surface. The apparatus also has a plurality of PPG sets (having at least one light source and at least one detector) extending through the platform contact surface, and a plurality of springs. Each PPG set is coupled with one or more of the springs to movably couple with the platform. In addition, each spring is biased to produce a biasing force via its coupled PPG set when the contact surface of the platform receives the foot. To maintain consistent pressure against the skin and good signal to noise ratio, each PPG set and its corresponding one or more springs are configured so that the biasing force has a magnitude that is substantially independent of the foot force magnitude.

Abstract: Systems and methods to monitor and track the treatment of bones using a bone correction system are provided. The method includes implanting growth modulating implants of a bone correction system in two or more bones of a patient. Each growth modulating implant includes an implant body having at least one sensor device embedded in the implant body. The method includes receiving sensor data from the sensor devices and determining an operational status of the growth modulating implants, based on the received sensor data. The method includes determining, by the processor, a longitudinal growth or growth rate between the two or more bones, based on the received sensor data and causing a display device to selectively display a graphical user interface (GUI) representative of at least one of the longitudinal growth and the growth rate of the patient.

Abstract: Disclosed are a method for diagnosing a vascular disease and an apparatus therefor. A vascular disease diagnosing method according to an exemplary embodiment of the present disclosure includes: an information acquiring step of acquiring patient information for a diagnosis subject; an FFR processing step of applying a geometric feature parameter information generated based on the patient information to a first learning model to calculate fractional flow reserve (FFR) information; a CFD processing step of applying the geometric feature parameter information to computational fluid dynamics (CFD) to calculate flow feature information; and a diagnosing step of determining a vascular disease based on the fractional flow reserve information and the flow feature information and determine whether to perform a surgery on the vascular disease.

Abstract: Devices and methods are provided for performing remote physiological monitoring of vital signs from one or more subjects. Camera pairs including an intensity camera and a depth camera are used to obtain intensity image data and depth image data that are then processed using one or more ROIs for extracting heart rate and respiratory waveforms from which the heart rate and respiratory rate may be estimated. In other embodiments, multiple ROIs may be used to obtain several heart rate and respiratory rate values which are then fused together. In some embodiments motion compensation may be used prior to generating the heart rate and respiratory waveforms. In other embodiments, multiple camera pairs may be used to obtain intensity and depth data from multiple fields of view which may be used to obtain several heart rate and respiratory rate values which are then fused together.

Abstract: Drug delivery articles, resident articles, and retrieval systems e.g., for gram-level dosing, are generally provided. In some embodiments, the residence articles are configured for transesophageal administration, transesophageal retrieval, and/or gastric retention to/in a subject. In certain embodiments, the residence article includes dimensions configured for transesophageal administration with a gastric resident system. In some cases, the residence article may be configured to control drug release e.g., with zero-order drug kinetics with no potential for burst release for weeks to months. In some embodiments, the residence articles described herein comprise biocompatible materials and/or are safe for gastric retention. In certain embodiments, the residence article includes dimensions configured for transesophageal retrieval. In some cases, the residence articles described herein may comprise relatively large doses of drug (e.g., greater than or equal to 1 gram).

Abstract: Systems and methods for diagnosing a condition in an individual by analyzing the individual's breath are provided. Sensors may be configured to capture data associated with the breath of an individual. The data captured by the sensors may include a change in resistance measurements recorded by solid-state sensors when the sensors are exposed to the individual's breath at several different temperatures. This captured data may be analyzed to identify one or more volatile organic compound (VOC) biomarkers in the individual's breath. Based on the identified VOC biomarkers, a condition associated with the individual may be determined. For example, a medical condition, or a condition of drowsiness or fatigue associated with the individual may be determined based on the VOC biomarkers in the individual's breath. In some examples, the sensors may be positioned inside a vehicle for determination of condition associated with a driver of the vehicle.

Abstract: A sphygmomanometer includes a main body mounted with a pump, a belt, and a cuff structure. The cuff structure having a band shape is disposed facing an inner circumferential surface of the belt in a freely separable manner from the inner circumferential surface of the belt. One end of the cuff structure is attached to the main body. The cuff structure includes a bag-shaped pressure cuff that extends along a circumferential direction of a measurement target site, a bag-shaped sensing cuff that extends in the circumferential direction across an artery passing portion of the measurement target site, and a back plate that is inserted between the pressure cuff and the sensing cuff. A blood pressure is calculated based on a pressure of a pressure transmission fluid contained in the sensing cuff.

Abstract: An apparatus for monitoring biometric information blood of a user that contains a housing that includes an electropermanent magnet, a battery, a processor, and a radio transmitter. A cap is magnetically coupled to the housing when a current is passed through a coil of the electropermanent magnet thereby compressing a portion of tissue of the user between the housing and the cap. By varying the compressive force applied to the tissue, the apparatus monitors at least one of blood pressure and heart rate from the response.

Abstract: An audiometric test method is provided where a noise stress test is applied to a subject, during the application of the noise stress test measuring one or more indicators reflecting a subjects purinergic hearing adaptation to noise exposure. The measured indicators are analysed to quantify degree of change and rate of change of the subjects purinergic hearing adaptation to noise exposure. An audiometric test system and audiometer configured to perform the test is also provided.

Abstract: An automatic system for making clinical decisions, especially with relation to cannabis use, that incorporates data from multiple personal tracking devices such as fitness trackers, analyzes that data using machine learning techniques to determine which data points are relevant to account for changes over time, and offers predictions, insights, and/or suggestions to support clinical decision making.

Abstract: A transdermal oxygen patch measures an oxygen concentration based on transcutaneous oxygen diffusing through an epidermal surface of a patient. Transcutaneous oxygen differs from hemoglobin-bound oxygen often measured in a patient blood flow. The patch employs an indicator responsive to an oxygen presence for emitting light having an intensity and lifetime (duration) based on the oxygen presence. An optical receptor is in communication with logic for receiving the intensity of emitted light and computing the oxygen concentration based on the received intensity and lifetime (duration). A wireless transmitter conveys the results to a base station or monitoring counterpart for untethered patient monitoring. Low power demands and circuit footprint are amenable to a wearable device such as a patch for continuous use.

Abstract: Systems and methods to determine a composite respiration phase of a patient are disclosed, including a signal receiver circuit to receive first and second physiologic information of a patient, and an assessment circuit to determine first respiration phase information of the first physiologic information and to determine the composite respiration phase of the patient using the determined first respiration phase information and the second physiologic information.

Abstract: A system and method for cardiovascular monitoring and reporting are disclosed. The system (CV monitoring system) includes a data analysis system and an in-ear biosensor system that preferably includes left and right earbuds. The earbuds include infrasound/vibration sensors that detect biosignals from the individual including signals associated with cardiovascular activity (CV signals). The analysis system calculates cardiovascular function measurements (CV function measurements) based upon the CV signals. The CV monitoring system uses machine learning to predict blood pressure (BP) measurements of the individual based upon the CV signals and the calculated CV function measurements. In an embodiment, the CV monitoring system includes an EKG detection system that detects EKG signals associated with heart function.

Abstract: An apparatus for sleep tracking may include (i) a sensor that detects whether a wearable device is being worn by a user, (ii) a mode-switching module that switches the wearable device between an active mode when the sensor detects that the wearable device is being worn by the user and a sleep-tracking mode when the sensor detects that the wearable device is not being worn by the user, (iii) a detector that, when the wearable device is in the sleep-tracking mode, detects signals associated with sleep behavior of the user, and (iv) a sleep-tracking module that, when the wearable device is in the sleep-tracking mode, monitors the user's sleep based at least in part on an evaluation of the signals associated with the sleep behavior of the user. Various other methods, systems, and computer-readable media are also disclosed.

Abstract: The invention provides a neck-worn sensor (referred to herein as the ‘necklace’) that is a single, body-worn system that measures the following parameters from an ambulatory patient: heart rate, pulse rate, pulse oximetry, respiratory rate, temperature, thoracic fluid levels, stroke volume, cardiac output, and a parameter sensitive to blood pressure called pulse transit time. From stroke volume, a first algorithm employing a linear model can estimate the patient's pulse pressure. And from pulse pressure and pulse transit time, a second algorithm, also employing a linear algorithm, can estimate systolic blood pressure and diastolic blood pressure. Thus, the necklace can measure all five vital signs along with hemodynamic parameters. It also includes a motion-detecting accelerometer, from which it can determine motion-related parameters such as posture, degree of motion, activity level, respiratory-induced heaving of the chest, and falls.

Abstract: A medical device such as an oximeter includes a marking feature. In an implementation, a marking mechanism of the device marks tissue based on a location of where a measurement was taken by the device. In an implementation, the marking mechanism of the device marks tissue based on an oxygen saturation measurement obtained by the device.

Abstract: There is provided an apparatus (100) for monitoring swallowing in a subject. The apparatus (100) comprises a processor (102) configured to acquire, from a motion sensor (104), motion signals obtained from a feeding tube, when placed in the esophagus of the subject. The motion signals are indicative of swallowing motions transmitted along the feeding tube. The processor (102) is also configured to process the acquired motion signals to classify the acquired motion signals as indicative of the subject swallowing healthily or unhealthily.

Abstract: A robust alarm system has an alarm controller adapted to input an alarm trigger and to generate at least one alarm drive signal in response. Alarm subsystems input the alarm drive signal and activate one or more of multiple alarms accordingly. A subsystem function signal provides feedback to the alarm controller as to alarm subsystem integrity. A malfunction indicator is output from the alarm controller in response to a failure within the alarm subsystems.