Abstract: Devices, methods, and systems are provided for occluding a collateral flow channel between a target lung compartment and an adjacent lung compartment. A video-assisted thoracoscopic device is inserted into a thoracic cavity of a patient and positioned at a fissure between a target lung compartment and an adjacent lung compartment. A collateral flow channel between the target lung compartment and the adjacent lung compartment is then identified using the video-assisted thoracoscopic device and an agent is injected into the collateral flow channel, thereby reducing the collateral flow channel.

Abstract: A device (901) is manufactured from a sheet layer (100) defining a plurality of panels (101,102,103). Each panel is connected to at least one other panel along a common edge (104). A perforation (105) extends along the common edge and defines a separation location allowing the each panel to be separated from adjoining panels when an applied force pulls each panel away from the adjoining panels. A score line (115) bisects each panel and is oriented orthogonally with the perforation. The score line allows a first portion (116) of each panel to fold about the score line to abut a second portion (117) of each panel. An adhesive (501), disposed along the first portion, retains the first portion to the second portion, as well as retains the filament between the first portion and the second portion.

Abstract: A biopsy needle unit includes a biopsy needle and an elastically deformable safety tube for partially covering the biopsy needle inserted to a lumen extending in a longitudinal direction. A marker is arranged on the biopsy needle at a position protruding from an end portion of the safety tube on an opposite side of a needle tip of the puncture needle when the needle tip portion is accommodated in the lumen. The safety tube has portions in which the lumen is curved at least partially with respect to the longitudinal direction so that the safety tube is elastically deformed due to contact between an inner circumferential face of the lumen and an outer circumferential face of the biopsy needle when the biopsy needle is inserted to the lumen to cause frictional resistance between the inner circumferential face of the lumen and the outer circumferential face of the biopsy needle.

Abstract: Methods of compensating for ambient temperature using a single temperature sensor, the method comprising detecting a first temperature measurement from a temperature sensor; and determining, with a processor, an ambient-compensated temperature from the first temperature measurement using an offset term. The method may also include receiving a sensor signal from an in vivo analyte sensor; and determining, with a processor, a temperature-compensated analyte sensor signal with the ambient-compensated temperature.

Abstract: The present invention provides an improved breath analyzer and breath test method to determine the presence of a gastrointestinal disorder in a subject's digestive tract.

Abstract: A blister strip which can be stuck onto the skin, is formed from at least two sheets and has an applicator for applying a medium contained in the blister to the skin, wherein the blister strip includes an upper sheet, with at least one protuberance, wherein the underside of the upper sheet, the underside enclosing the protuberance, is of adhesive configuration. The blister strip has a lower sheet, which covers the lower surface of the blister strip and can be drawn off from the adhesive underside of the upper sheet. The protuberance contains an applicator, separating the protuberance into at least two sub-volumes. Wherein the applicator has at least one opening, which connects two sub-volumes, wherein one sub-volume is located between the applicator and the lower sheet, and wherein at least one sub-volume is entirely surrounded by the inner surface of the protuberance and the applicator, and contains the medium.

Abstract: Devices, systems, and methods for visually depicting a vessel and evaluating treatment options are disclosed.

Abstract: A protective liner for use with a blood pressure measuring cuff includes three layers of material configured to protect a person's skin, wick moisture away from the person's skin, and provide a moisture permeable, microporous barrier to microbes. The protective liner is porous and sufficiently thin so that the protective liner will not substantially interfere with blood pressure monitoring through the protective liner. The three layers of material are configured to wick moisture therethrough away from the person's skin, while substantially preventing passage of microbes therethrough.

Abstract: A synthetic aperture photoplethysmography (PPG) sensor is disclosed. A group or matrix of contiguous PPG sensors located on a toilet seat are conditionally combined based on sensor measurements. Conditional combinations may be based on timing data and signal-to-noise ratio data of each of the PPG measurements. Measurements associated with the conditional combinations are then used to determine a cardiac function of a toilet user.

Abstract: A method for continuously detecting body physiological information trajectories through the use of a personal wearable device. Through short-distance wireless transmission, a smartphone or a computer first transmits basic information, including a personal ID of a user of the device, a device ID, an ID of the smartphone or the computer, and communication links, to a remote medical data center. In this case, the device continuously detects body physiological information which can be transmitted to the remote medical data center. Corrective body physiological information data of the user is measured and transmitted to the remote medical data center. The remote medical data center processes the data and periodic pulse volume curves. The remote medical data center then transmits the numeral data converted from periodic pulse volume curves back to the personal wearable device and continuously constructs a periodic trajectory of detected personal body physiological information.

Abstract: Device for contactless monitoring of a patient's vital signs in the form of a measuring mat comprising at least one measuring element. The measuring element comprises a piezoelectric sensor with a first and a second conductive electrode and a piezoelectric element. Near the piezoelectric sensor is a third conductive electrode. The exertion of a mechanical force on the cover of the measuring element results in a change in the distance between at least one of the electrodes of the piezoelectric sensor and the third conductive electrode. This change in distance is expressed as a difference in the detected parameter corresponding to a change in the patient's vital signs.

Abstract: Systems and methods of use involving sensors having a signal-to-noise ratio that is substantially unaffected by non-constant noise are provided for continuous analyte measurement in a host. In some embodiments, a continuous analyte measurement system is configured to be wholly, transcutaneously, intravascularly or extracorporeally implanted.

Abstract: A medical device includes an antenna external to a case, package, or encapsulant for the electronic systems of the medical device. In one embodiment, a diabetes infusion pump is enclosed within a metal case, the pump including a processor and a communication module for wireless communications. An antenna is disposed in the delivery tubing of the pump outside the case with an antenna feed interconnecting the external antenna with the internal communication module. In another aspect, a thin film antenna is formed on the outer surface of the case in which a physiological parameter sensor, such as a glucose sensor, is enclosed. Multiple antennas may be used for communications on different frequencies.

Abstract: Systems and methods for analyte monitoring, particularly systems and methods for monitoring and managing life of a battery in an analyte sensor system worn by a user, are provided.

Abstract: Gated physiological monitoring systems and methods are described that utilize a photoplethysmogram (PPG) monitoring device and another (different) physiological monitoring device, where the PPG monitoring device is operated based on timing information obtained from the other physiological monitoring device. In some implementations, control circuitry can be configured to operate the PPG monitoring device based on timing information from a physiological waveform detected by the physiological monitoring device. For example, the control circuitry can operate the PPG monitoring device to capture one or more selected portions of a measured PPG waveform that can then be used to estimate the full PPG waveform or portions of interest.

Abstract: A method and apparatus for monitoring a cardiovascular pressure signal in a medical device that includes determining whether the sensed pressure signal is greater than a first pressure threshold, determining a first metric of the pressure signal in response to the sensed pressure signal being greater than the first pressure threshold, determining whether the sensed pressure signal is greater than a second pressure threshold not equal to the first pressure threshold, determining a second metric of the pressure signal in response to the sensed pressure signal being greater than the first pressure threshold, and determining at least one of a systolic pressure or a diastolic pressure, wherein the at least one of a systolic pressure or a diastolic pressure is determined based on the first metric in response to the pressure signal not being greater than the second threshold, and based on the second metric in response to the pressure signal being greater than the second threshold.

Abstract: A device for generating alerts for Hypo and Hyperglycemia Prevention from Continuous Glucose Monitoring (CGM) determines a dynamic risk based on both information of glucose level and a trend obtainable from a CGM signals. The device includes a display whose color depends on the DR (for example, red for high DR, green for low risk). When DR exceeds a certain threshold, alerts are generated to suggest the patient to pay attention to the current glucose reading and to its trend, both of which are shown on the display in numbers and symbols (e.g. an arrow with different slope or color).

Abstract: A system for measuring blood pressure of a user that comprises an ElectroCardioGram (ECG) circuit with at least two ECG electrodes configured to obtain an electrical activity of a heart of the user by measuring the electrical signals detected at the at least two ECG electrodes as an electrocardiogram waveform, and a pulse oximeter circuit configured to obtain a pulse waveform corresponding to a blood flow on user's vessels. The system further comprises a processor that is in electrical contact with the electrocardiogram circuit and the pulse oximeter circuit. The processor is configured to simultaneously analyze the electrocardiogram waveform and the pulse waveform. The processor is further configured to identify a “Zero Voltage Crossing” point on the electrocardiogram waveform and to determine time delays from this point to respective different determined points of the pulse waveform; and to use the time delays to compute the blood pressure values.

Abstract: An implantable pressure sensor device (100) has a housing (10) which is at least partially made of a pressure transmitting membrane (20), and which includes one or more regions which can reversibly deform while maintaining the surface area of the membrane (20) when the internal volume of the housing (10) is changed. The housing (10) has a non-circular cross-section which can deform to a more circular shape when pressure in the internal volume increases. An inner housing is preferably situated within the housing, with its exterior spaced from the interior of the housing, and has its inner volume in fluid communication with the space between the housing and inner housing.

Abstract: Airway impedance of a subject using a respiratory treatment device can be measured, in accordance with one or more embodiments. A conduit is configured to communicate a flow of inhaled gas and a flow of exhaled gas to and from an airway of the subject using the respiratory treatment device. A first valve is disposed within the conduit and configured to affect the flow of exhaled gas. One or more sensors are disposed within the conduit and are configured to provide a signal conveying information associated with one or more characteristics of gas exhaled by the subject while the flow of exhaled gas is affected or unaffected by the first valve. An airway impedance monitoring module can be executed by a processor to determine an impedance metric of the airway of the subject based on the information conveyed by the signal provided by the one or more sensors.