Abstract: Embodiments disclosed herein improve digital stethoscopes and their application and operation. A first method detects of a respiratory abnormality using a convolution. A second method counts coughs for a patient. A third method predicts a respiratory event based on a detected trend. A fourth method forecasts characteristics of a future respiratory event. In a fifth embodiment, a base station is provided for a digital stethoscope.

Abstract: Catheter systems and methods for determining blood flow rates based on temperature measurements by thermodilution. The catheter may include a fluid lumen defined between inner and outer tubular members for delivering an indicator fluid, and a guidewire lumen defined by the inner tubular member. The catheter may include fluid infusion openings at the distal end region of the outer tubular member configured to permit the indicator fluid to exit the catheter from the fluid lumen, and a fluid hole located at the distal end region of the inner tubular member configured to permit the indicator fluid to pass from the fluid lumen into the guidewire lumen. A temperature sensor positioned on a guidewire may be positioned within the guidewire lumen to measure the temperature of the indicator fluid entering the guidewire lumen through the fluid hole. A blood flow rate may be calculated based on the measured temperature.

Abstract: Analyte sensor faults are detected. Datasets of glucose values sensor electronics are coupled to a glucose sensor in fluid contact with interstitial fluid under a skin surface. Baseline median glucose value and glucose variability values are computed, based on the first dataset. A baseline data point is stored. Evaluation median glucose value and variability are computed, based on the second dataset of glucose values. An evaluation data point is stored. A magnitude of a vector that extends between the baseline data point and the evaluation data point is computed. A component of the magnitude of the vector that is parallel to a hypoglycemia risk contour line is computed and compared to a predefined threshold value. An indication that a sensor fault has been detected if the component is greater than a threshold is displayed.

Abstract: Embodiments disclosed herein improve digital stethoscopes and their application and operation. A first method detects of a respiratory abnormality using a convolution. A second method counts coughs for a patient. A third method predicts a respiratory event based on a detected trend. A fourth method forecasts characteristics of a future respiratory event. In a fifth embodiment, a base station is provided for a digital stethoscope.

Abstract: The present system is directed in various embodiments to devices, systems and methods for detection, evaluation and/or monitoring olfactory dysfunction by measuring and determining the patient's olfactory detection threshold for the left and the right nostril. In some cases, the present invention relates to devices, systems and methods for detecting an asymmetric differential in a patient's relative olfactory detection and/or identification threshold (left vs right nostril) which, when present, may be used as a device to detect, diagnose and/or monitor olfactory deterioration resulting from Alzheimer's disease, and/or the efficacy of treatment regimens therefor over time. Alternatively, general olfactory dysfunction may be evaluated and/or monitored without regard to the individual nostril's performance.

Abstract: A blood pressure estimation apparatus includes: a pulse wave measurement unit measuring a user's pulse wave signal; an electrocardiogram signal measurement unit measuring a user's electrocardiogram signal; and a processing circuit estimating a user's blood pressure value by using the pulse wave and electrocardiogram signals, wherein the processing circuit (a) acquires a pulse wave signal feature by using the pulse wave signal, (b) acquires an electrocardiogram signal feature by using the electrocardiogram signal, (c) acquires a pulse wave propagation time by using the pulse wave and electrocardiogram signals, (d) selects a blood pressure group indicating a relationship between a pulse wave propagation time and blood pressure of the user by using the pulse wave signal feature, electrocardiogram signal feature, and pulse wave propagation time, and (e) estimates the blood pressure value by using the blood pressure group, pulse wave signal feature, electrocardiogram signal feature, and pulse wave propagation time

Abstract: The present document describes a pressure guidewire. It comprises a shaft tube having a proximal section and a sensor housing having a distal end, the proximal section and the sensor housing being the continuity of the same shaft tube. A fiber optic pressure sensor is embedded in the sensor housing and comprises an optical fiber extending within the sensor housing, the sensor adapted to measure a pressure of a fluid which is substantially applied in an axis collinear with the longitudinal axis of the guidewire. A marker band, to help in localizing the pressure guidewire in a patient's vessels, is embedded inside the sensor housing and fixed to the optical fiber for holding the pressure sensor inside the sensor housing.

Abstract: Embodiments disclosed herein improve digital stethoscopes and their application and operation. A first method detects of a respiratory abnormality using a convolution. A second method counts coughs for a patient. A third method predicts a respiratory event based on a detected trend. A fourth method forecasts characteristics of a future respiratory event. In a fifth embodiment, a base station is provided for a digital stethoscope.

Abstract: In some aspects, an apparatus for a biosensor includes a sensor wire and a rigid member. The rigid member may be coupled to the sensor wire and include a contact surface. The contact surface may be sized to enable a suction head of a robotic placement device to create a vacuum seal on the contact surface for lifting the sensor wire and rigid member.

Abstract: Aspects of the disclosure can provide a method and device for detecting EEG signals of a first person in proximity to the device. The device can include a non-contact EEG directional circuit having non-contact sensors, the non-contact EEG directional circuit being configured to detect the EEG signals produced by a brain of the first person without making contact with the first person. The device can further include a processor coupled to the non-contact EEG directional circuit that is configured to analyze the EEG signals to detect patterns in the EEG signals that correspond to a state of the first person in proximity to the non-contacting sensor and a feedback device that is configured to provide a second person with an indication of the state of the first person in proximity to the non-contacting sensor.

Abstract: A sensor system comprises first and second PPG sensors. A monitoring system monitors detection by at least one of the first and second detectors an optical calibration signals, for performing time calibration between the first and second PPG sensors. This system makes use of two PPG sensors. To enable these sensors to be independent units, rather than being fully integrated into a combined system, a calibration system is provided. Based on detected optical signals, the behavior over time of each PPG sensor can be monitored and thus calibration can take place.

Abstract: A sensor system comprises first and second PPG sensors. A monitoring system monitors detection by at least one of the first and second detectors an optical calibration signals, for performing time calibration between the first and second PPG sensors. This system makes use of two PPG sensors. To enable these sensors to be independent units, rather than being fully integrated into a combined system, a calibration system is provided. Based on detected optical signals, the behavior over time of each PPG sensor can be monitored and thus calibration can take place.

Abstract: A device system and method for wirelessly communicating through tissue is provided. The device system comprises an implanted device with an array of antennas aligned with a tandem device with an array of antennas outside of the body. The two devices wirelessly communicate in a bi-directional manner. The implanted device can act as a physiological sensor and stimulator, and the external device can act as a controller and relay. Such configurations allow for a range of uses within research and clinical settings.

Abstract: An olfactory examination apparatus includes: an odor generating unit having an odorant generating mechanism that stores an odorant and generates an odorous gas having a defined concentration or an defined intensity and an odorless gas generating mechanism; a gas supply unit configured to alternately supply an odorous gas or an odorless gas having a defined concentration or a defined intensity of the odor from the odorant generating mechanism and the odorless gas generating mechanism to an examinee through an odor presentation mechanism placed on a nostril portion of the examinee, and a reply unit that allows the examinee to express an answer when smelling the odorant in order to examine an olfactory function.

Abstract: Devices and methods of making and using the device for the non-invasive detection of volatile anesthetics are provided. The devices are capable of measuring the concentration of volatile anesthetics transdermally and in a non-invasive manner. The devices and methods can be applied in detection of volatile anesthetics in samples collected from human skin perspiration.

Abstract: An implantable medical device comprising a battery cell including: an anode; a cathode including fluorinated carbon particles; a separator between the anode and the cathode; and an electrolyte contacting the anode, the cathode, and the separator; wherein greater than 50 vol-% of the fluorinated carbon particles have a particle size within a range of 2 microns to 10 microns, and greater than 50% by number have an aspect ratio within a range of 1:1.2 to 1:8.

Abstract: Implantable sensor apparatus and methods of implantation. In one embodiment, a fully implantable, biocompatible sensor is disposed within a cavity or pocket formed within a living being, such that the sensor remains in a desired orientation and placement so as to enhance the performance of the sensor, and mitigate the effects of one or more factors potentially deleterious to the operation of the sensor and the host being. In one implementation, the sensor comprises an implantable biocompatible oxygen-based glucose sensor which is implanted deep within the being's torso tissue proximate the extant fascia, and oriented such that an active detector aspect of the device faces away from the being's skin surface. In one variant, the deep placement, orientation, and construction of the sensor itself cooperate to enhance the performance of the sensor, especially over extended periods of time, with little need for external calibration.

Abstract: The system and method for measuring arterial pressure by its effects consists of a six-stage procedure and three devices; the procedure to indirectly measure diastolic arterial pressure controls the tasks of a first device applying a measured gradual external contact force, a second sensor device of arterial that records arterial expression, and a third device which is a device to measure and detect the arterial cycle diastolic and systolic period in order to provide the diastolic arterial pressure value using an indirect method. Additionally, systolic arterial pressure is measured with no overpressure due to heartbeats produced after arterial occlusion.

Abstract: Athletic activity may be monitored using heart rate in addition to or instead of other types of metrics. Accordingly, multiple different activity types may be compared based on heart rate information. Additionally, the heart rate information may be visualized by displaying the heart rate data over time or relative to pace or distance. Additionally, the system may allow a user to analyze his or her heart rate performance by identifying one or more portions of the athletic activity in which a user exhibited a specified range of heart rates. Athletic activity sessions may further be tagged with various indicators including weather, terrain, difficulty and intensity. According to one or more aspects, data for different types of activity metrics may be polled and/or transmitted to a system at different rates or based on different schedules. Moreover, users may specify whether sensed data may be uploaded, recorded and/or visualized prior to or during an activity session.

Abstract: Approaches presented herein enable performing an oral health diagnosis of a user using an oral monitoring device fixed in the oral cavity. Specifically, an oral monitoring device collects jaw movement data as a user goes about daily living. An oral healthcare analysis is performed comparing current measurement data against abnormality classifications to identify abnormal jaw movement. If an abnormality is identified, an oral healthcare professional can be notified.