Abstract: The invention relates to substituted thiophenyl uracils of general formula (I) or the salts (I) thereof, wherein the groups in general formula (I) are as defined in the description, and to the use thereof as herbicides, in particular for controlling weeds and/or weed grasses in crops of cultivated plants and/or as plant growth regulators for influencing the growth of crops of cultivated plants.
Type:
Grant
Filed:
December 17, 2018
Date of Patent:
November 15, 2022
Assignee:
Syngenta Crop Protection AG
Inventors:
Ines Heinemann, Jens Frackenpohl, Lothar Willms, Roland Beffa, Hansjörg Dietrich, Elmar Gatzweiler, Anu Bheemaiah Machettira, Christopher Hugh Rosinger, Peter Lümmen, Elisabeth Asmus
Abstract: The present application relates to a method of weed control for a crop field using a synergistic effect of two herbicides cellulosin and isoxaben. A composition matter together with said method comprising cellulosin and isoxaben is within the scope of the present invention.
Abstract: An inhalable dry powder formulation containing SAE-CD and an active agent is provided. The formulation is adapted for administration by DPI. The SAE-CD serves as a carrier rather than as an absorption enhancer. The average particle size of the SAE-CD is large enough to preclude (for the most part) pulmonary deposition thereof. Following release from the DPI device, the SAE-CD-containing particles dissociate from the active agent-containing particles in the buccal cavity or throat, after which the active agent-containing particles continue deeper into the respiratory tract. The physicochemical and morphological properties of the SAE-CD are easily modified to permit optimization of active agent and carrier interactions. Drugs having a positive, neutral or negative electrostatic charge can be delivered by DPI when SAE-CD is used as a carrier.
Type:
Grant
Filed:
May 15, 2020
Date of Patent:
October 11, 2022
Assignee:
CyDex Pharmaceuticals, Inc.
Inventors:
James D. Pipkin, Gerold L. Mosher, Douglas B. Hecker
Abstract: Compounds of formula (I) as defined herein, to processes for preparing them, to pesticidal, in particular insecticidal, acaricidal, molluscicidal and nematicidal compositions comprising them and to methods of using them to combat and control pests such as insect, acarine, mollusc and nematode pests.
Type:
Grant
Filed:
October 4, 2018
Date of Patent:
October 4, 2022
Assignee:
Syngenta Participations AG
Inventors:
Aurelien Bigot, Myriem El Qacemi, Denis Gribkov, André Stoller
Abstract: The objective of the present invention is to provide a contact lens solution that is safer to eyes such that it has little or no effects on eye tissue and has the versatility that makes the solution applicable to a wide range of contact lenses, while exhibiting desirable anti-Acanthamoeba activity. The objective is achieved by the anti-Acanthamoeba contact lens solution containing a cationic polymer having an average molecular weight in a range of 150,000 to 1,600,000 and having in its molecule a diallyldimethylammonium chloride unit and an inorganic salt.
Abstract: Compositions, methods, and kits for treating dry eye and related diseases are provided. In one aspect, the present disclosure relates to administering thermoresponsive polymeric compositions to the tear duct of the subject. Administering a thermoresponsive polymeric composition to the tear duct of the subject may be useful in treating dry eye and related conditions.
Abstract: The present invention provides compositions and methods for the delivery of therapeutic agents to cells. In particular, these include novel, trialkyl, cationic lipids and nucleic acid-lipid particles that provide efficient encapsulation of nucleic acids and efficient delivery of the encapsulated nucleic acid to cells in vivo. The compositions of the present invention are highly potent, thereby allowing effective knock-down of a specific target protein at relatively low doses.
Abstract: The invention provides crystalline forms of biphenyl-2-ylcarbamic acid 1-(2-{[4-(4-carbamoylpiperidin-1-ylmethyl)benzoyl]methylamino}ethyl)piperidin-4-yl ester, and pharmaceutically acceptable solvates thereof. The crystalline form can be a freebase, or a salt such as a diphosphate, monosulfate or dioxalate salt. The invention also provides pharmaceutical compositions comprising these crystalline compounds or prepared using these compounds; processes and intermediates for preparing the crystalline compounds; and methods of using these compounds to treat a pulmonary disorder.
Abstract: Provided are bioactive compositions and metabolites derived from Bacillus and particularly Bacillus megaterium cultures responsible for controlling pests as well as their methods of use for controlling pests. Further provided are pesticidal Bacillus megaterium strains.
Type:
Grant
Filed:
March 30, 2020
Date of Patent:
July 12, 2022
Assignee:
MARRONE BIO INNOVATIONS, INC.
Inventors:
Ratnakar Asolkar, Ana Lucia Cordova-Kreylos, Margarita Rodriguez, Carly Todd, Debora Wilk, Pamela G. Marrone
Abstract: Compounds of formula (I) as defined herein, to processes for preparing them, to pesticidal, in particular insecticidal, acaricidal, molluscicidal and nematicidal compositions comprising them and to methods of using them to combat and control pests such as insect, acarine, mollusc and nematode pests.
Type:
Grant
Filed:
October 4, 2018
Date of Patent:
July 12, 2022
Assignee:
Syngenta Participations AG
Inventors:
Aurelien Bigot, Myriem El Qacemi, Denis Gribkov, André Stoller
Abstract: Provided herein are compounds that exhibit activity as acetyl-CoA carboxylase modulators (e.g., inhibitors) and are useful, for example, in methods for the control of fungal pathogens in plants.
Type:
Grant
Filed:
January 7, 2020
Date of Patent:
July 5, 2022
Assignee:
Monsanto Technology LLC
Inventors:
Urszula Slomczynska, Matthew W. Dimmic, William P. Haakenson, Jr., Jennifer L. Bennett, Barry J. Shortt, Christina M. Taylor, Deryck Jeremy Williams, Martin Slater
Abstract: The present invention can provide a method having superior safety for protecting determinate soybean from damage by a plant pathogen. The method includes a step of applying mefentrifluconazole to foliage of determinate soybean, seeds of determinate soybean or a soil of the cultivation area of determinate soybean, wherein the application rate of mefentrifluconazole is 20 to 500 g per hectare of cultivation area.
Abstract: Disclosed are compounds of Formula 1, including all stereoisomers, N-oxides, and salts thereof wherein W, R1, J, Q1, R7, R8, Y, R9 and are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling undesired vegetation comprising contacting the undesired vegetation or its environment with an effective amount of a compound or a composition of the invention.
Abstract: The present invention relates to compounds of formula (I) that are useful as perfuming ingredients of the fruity type. Formula (I) is in the form of any one of its stereoisomers or of a mixture thereof, wherein R1 represents a C1-3 alkyl or alkenyl group, R2 represents a methyl or ethyl group, R3 represents a C1-4 alkyl or alkenyl group, and the compound (I) has from 8 to 12 carbon atoms.
Abstract: The present invention relates to increasing and/or maintaining nitrogen content in soil by administration of granular or powdered nitrification inhibitors coated with urease inhibitors. In one embodiment, urease inhibitors are dispersed in an improved organo liquid delivery system at concentration levels of 50-90%. In another embodiment, urease inhibitors were applied in a non-aqueous, organo liquid delivery system coating solid nitrification inhibitors utilizing simple blending equipment at temperatures of 20°-70° C. Another embodiment discloses a dry, flowable additive containing a nitrification inhibitor coated with a urease inhibitor which can be administered directly to the soil, to a dry natural and/or a manmade fertilizer or to a liquid fertilizer which provides for the reduction of nitrogen loss from the soil.
Type:
Grant
Filed:
February 15, 2018
Date of Patent:
June 7, 2022
Assignee:
WORLD SOURCE ENTERPRISES, LLC
Inventors:
Gary David McKnight, Randall Linwood Rayborn, Charles J. Barber, Wei Xu
Abstract: The invention relates to novel compounds of the formula (I) in which R1, R2, R3, R4, R5, R6, R7, R8, A1, A2, A3 and n each have the meanings given above, to their use as acaricides and/or insecticides for controlling animal pests and to processes and intermediates for their preparation.
Abstract: A composition for weed control and fertilizer comprising iron hydroxyl ethylenediaminetriacetic acid, humate, microelements, soy hydrolysate, calcium lignin, a natural-based wetting agent, molasses desurgarized solubles, and water, and may further comprise glycerin and/or preservatives, are provided. Methods for weed control and fertilization of plants comprising the steps of providing a composition comprising an effective amount of iron hydroxyl ethylenediaminetriacetic acid, humate, microelements, soy hydrolysate, calcium lignin, a natural-based wetting agent, and molasses desurgarized solubles, and applying an effective amount of the composition to soil or a plant or a weed, are also provided.
Abstract: The present invention relates to forchlorfenuron mixtures. The present invention further relates to methods of promoting or synchronizing bud break in woody perennial plants by applying forchlorfenuron mixtures of the present invention. The present invention further relates to methods of promoting plant growth in woody perennial plants by applying forchlorfenuron mixtures of the present invention.
Type:
Grant
Filed:
February 22, 2019
Date of Patent:
May 3, 2022
Assignee:
VALENT BIOSCIENCES LLC
Inventors:
Franklin Paul Silverman, Robert Erwin Fritts, Jr., Derek D. Woolard, Marci Ann Surpin, Steve McArtney
Abstract: The present invention provides apparatus and processes for producing liposomes. By providing a buffer solution in a first reservoir, and a lipid solution in a second reservoir, continuously diluting the lipid solution with the buffer solution in a mixing chamber produces a liposome. The lipid solution preferably comprises an organic solvent, such as a lower alkanol.
Type:
Grant
Filed:
May 25, 2021
Date of Patent:
May 3, 2022
Assignee:
ARBUTUS BIOPHARMA CORPORATION
Inventors:
Ian MacLachlan, Lloyd B. Jeffs, Lorne R. Palmer, Cory Giesbrecht
Abstract: The present invention provides apparatus and processes for producing liposomes. By providing a buffer solution in a first reservoir, and a lipid solution in a second reservoir, continuously diluting the lipid solution with the buffer solution in a mixing chamber produces a liposome. The lipid solution preferably comprises an organic solvent, such as a lower alkanol.
Type:
Grant
Filed:
May 25, 2021
Date of Patent:
April 12, 2022
Assignee:
ARBUTUS BIOPHARMA CORPORATION
Inventors:
Ian MacLachlan, Lloyd B. Jeffs, Lorne R. Palmer, Cory Giesbrecht