Abstract: The invention relates to alkyl benzoate mixtures, the sum of the C12- and C14-alkyl benzoates being greater than or equal to 85%, in relation to the total sum of the alkyl benzoates. The invention also relates to the use of said alkyl benzoate mixtures in cosmetic and/or pharmaceutical preparations, in particular as oil components.
Type:
Grant
Filed:
September 18, 2007
Date of Patent:
December 11, 2012
Assignee:
Cognis IP Management GmbH
Inventors:
Achim Ansmann, Rolf Kawa, Hans-Dieter Clages, Lars Zander
Abstract: The present invention is directed to the provision of multi-dose, self-preserved ophthalmic compositions. The compositions possess sufficient antimicrobial activity to satisfy USP preservative efficacy requirements, as well as similar preservative standards (e.g., EP and JP), without requiring the presence of conventional anti-microbial preservative agents, such as benzalkonium chloride. The compositions are effectively preserved by a balanced ionic buffer system containing zinc ions at a concentration of 0.04 to 0.9 mM, preferably 0.04 to 0.4 mM. One aspect of the balanced buffer system is limitation of the amount of buffering anions present to a concentration of 15 mM or less, preferably 5 mM or less. In a preferred embodiment, the compositions also contain borate or, most preferably, one or more borate/polyol complexes. The use of propylene glycol as the polyol in such complexes is strongly preferred.
Type:
Grant
Filed:
April 14, 2011
Date of Patent:
December 4, 2012
Assignee:
Alcon Research, Ltd.
Inventors:
Bhagwati P. Kabra, Masood A. Chowhan, L. Wayne Schneider, Wesley Wehsin Han
Abstract: A nail varnish additive contains a) at least one silane of the general formula wherein the radicals R1, R2, R3, R4 are identical or different, have 1 to 40 carbon atoms and are non-crosslinking, and optionally b) at least one solvent.
Abstract: The present invention relates to compositions including medium chain peroxycarboxylic acid, methods for making these compositions, and methods for reducing the population of a microorganism. The compositions can include advantageously high levels of the medium chain peroxycarboxylic acid, can be readily made, and/or can exhibit reduced odor.
Type:
Grant
Filed:
September 29, 2011
Date of Patent:
November 27, 2012
Assignee:
Ecolab USA Inc.
Inventors:
Victor F. Man, Joshua P. Magnuson, Steven E. Lentsch
Abstract: Compositions comprising from about 40 weight parts to about 1000 weight parts of a botanical nitrate source; from about 20 weight parts to about 500 weight parts of a botanical source of nitrite reduction activity; and from about 4 weight parts to about 100 weight parts of a nitrite salt. Methods of reducing triglycerides or reducing C-reactive protein levels are also provided.
Type:
Grant
Filed:
August 16, 2010
Date of Patent:
November 6, 2012
Assignees:
Board of Regents, The University of Texas System, Neogenis Laboratories, Inc.
Abstract: The present invention relates to a method of covering a metal article with a film formed from the melting of a thin layer of powder comprising: physically blending 99.8 to 97% by weight of at least one polyamide and 0.2 to 3% by weight of an inorganic biocide species consisting of a soluble ceramic in which silver ions are encapsulated to form a powder blend composition; contacting the metal article with said powder composition blend to form a thin layer of said powder on the article; melting the powder blend composition onto the metal article to form a thin coating film; and cooling the coated article; where the powder blend composition is free of zinc compounds.
Abstract: Compositions comprising a nitrite salt, a nitrate salt, and ascorbic acid are provided in several embodiments. Use of said composition in a method of enhancing cardiovascular performance or treating adverse cardiovascular event in a mammal is also provided.
Type:
Grant
Filed:
June 15, 2009
Date of Patent:
October 30, 2012
Assignee:
Board of Regents, The University of Texas System
Abstract: An oily dispersion of an inorganic microparticle oxide powder that exhibits excellent texture has superior compatibility with other cosmetic material components. The oily dispersion contains only two components of a dispersion medium and a surface-treated inorganic microparticle oxide powder, wherein the dispersion medium is an oil, the surface-treated inorganic microparticle oxide powder is a powder surface-treated with branched fatty acid containing isostearic acid as a primary constituent component or a metal salt containing isostearic acid as a primary constituent component at an amount of 1 to 30% by weight with respect to the powder as a base material, and the surface-treated inorganic microparticle oxide powder has a solid concentration of 25% by weight or more and a viscosity of 2,000 mPa·s or less at 25° C. in the preparation of the oily dispersion.
Abstract: A process for the hydrogenation of a mixture of caryophyllenes by contact with hydrogen in the presence of a supported catalyst. The resulting products are useful for the application to skin.
Type:
Grant
Filed:
December 20, 2007
Date of Patent:
October 23, 2012
Assignee:
E I du Pont de Nemours and Company
Inventors:
Keith W. Hutchenson, Scott Christopher Jackson, Leo Ernest Manzer, Mark A. Scialdone, Mayis Seapan
Abstract: Provided are methods of treating pain, including neuropathic pain, in human and veterinary individuals. These methods employ locally administrable pharmaceutical gallium compositions, including pharmaceutical gallium compositions suitable for administration to the skin and mucous membranes. The compositions comprise pharmaceutically acceptable gallium compounds, such as gallium maltolate or gallium nitrate, together with pharmaceutically acceptable carriers suitable for local administration, including those suitable for topical administration. The administration of such compositions provides relief from pain, itching, allodynia, hyperalgesia, and related symptoms.
Abstract: The invention relates methods of reducing the risk or preventing the occurrence of an adverse event (AE) or a serious adverse event (SAE) associated with a medical treatment comprising inhalation of nitric oxide.
Abstract: The invention relates methods of reducing the risk or preventing the occurrence of an adverse event (AE) or a serious adverse event (SAE) associated with a medical treatment comprising inhalation of nitric oxide.
Abstract: The present invention utilizes a fatty acid as an attractant in a method of attracting whiteflies. By using a fatty acid as a whitefly attractant, it is possible to attract whiteflies to a desired location. The fatty acid can be used in a lure or other propagator to provide a dispersion of fatty acid in the air, the variation in the concentration of the fatty acid in the air being such that a whitefly is attracted to the lure as the source of the fatty acid. The use of a fatty acid as an attractant results in significantly higher levels of attraction, as measured by the number of whiteflies attracted to a sticky trap, as compared to the use of color alone.
Abstract: The present invention is directed to a reinforced absorbable hemostat comprising at least one hemostatic agent in a single layer of nonwoven synthetic fabric having a mixture of compressed fiber staples of a polyglycolide/polylactide copolymer and a polydioxanone.
Type:
Grant
Filed:
May 17, 2010
Date of Patent:
September 25, 2012
Assignee:
Ethicon, Inc.
Inventors:
Olajompo Moloye-Olabisi, Dhanuraj S. Shetty, Robert W. Van Holten, Degang Zhong
Abstract: A method for treating diseased plants, such as turf and trees, includes mixing a quantity of a plant remediation composition with water and applying the plant remediation composition to the diseased plants. The plant remediation composition may include from about 70 up to about 90 volume percent of a potassium silicate, up to 10 volume percent of a sodium silicate, from about 0.25 to about 3.0 volume percent of a surfactant, from about 0.25 to about 3.0 volume percent of a polyol, and the remaining volume percent water. The plant remediation composition may be used to treat plant molds, bacteria and fungi, such as Anthracnose, Fairy Ring, Brown Patch, Dollar Spot, and Snow Mold, and may also be used to prevent and remediate insect infestations.
Abstract: The present invention relates to compositions and methods for transdermal drug delivery comprising formulating a phosphatidylcholine carrier composition containing the drug and applying the composition to the skin.
Abstract: A hair cosmetic composition, containing the following Components (A) to (D): (A) benzyl alcohol, from 0.1 to 2% by mass; (B) dipropylene glycol, from 0.5 to 20% by mass; (C) malic acid or a salt thereof, from 0.2 to 10% by mass, in terms of the malic acid; and (D) lactic acid or a salt thereof, from 0.2 to 10% by mass, in terms of the lactic acid; and optionally containing a surfactant (E) at a concentration of 2% by mass or less and at a Component (E)/Component (A) mass ratio falling within a range of from 0 to 5.
Abstract: A nutritional supplement for use in physiologically stressful conditions is disclosed. The nutritional supplement may include one or more of vitamin A, vitamin E, vitamin D3, vitamin C, vitamin B1, riboflavin, niacin, folic acid, vitamin B6, biotin, pantothenic acid, vitamin B12, magnesium, zinc, selenium, chromium, copper, iron, alpha lipoic acid, lutein and lycopene.
Type:
Grant
Filed:
March 8, 2011
Date of Patent:
September 11, 2012
Assignee:
Vertical Pharmaceuticals, Inc.
Inventors:
Steven A. Squashic, Kevin M Hudy, David C. Purdy
Abstract: The present invention provides a solid preparation containing an insulin sensitizer and an active ingredient (except insulin sensitizers), which shows in vivo dissolution behavior of an insulin sensitizer, which is similar to the dissolution behavior of an insulin sensitizer from “a solid preparation containing an insulin sensitizer alone as an active ingredient”. The present invention provides a solid preparation containing (1) a layer containing an insulin sensitizer, and (2) a layer containing (a) an active ingredient (except insulin sensitizers), (b) microcrystalline cellulose having a mean particle size of 5-25 ?m, (c) microcrystalline cellulose having a mean particle size of 30-100 ?m and (d) polyvinylpyrrolidone K-90.