Patents Examined by Everett White
  • Patent number: 11365266
    Abstract: A method for producing a cellulose ether having a high viscosity while keeping the same degree of polymerization as that in the production of a shaped pulp without changing a raw material or production facility. More specifically, provided is a method for producing a cellulose ether including steps of: cutting or pulverizing pulp to obtain sheet-like, chip-like, or powdery cellulose pulp, wherein the pulp is formed in a form of roll whose surface layer on at least one of the circumferential side and the ends is removed, or in a form of bale whose surface layer on at least one side is removed; bringing the obtained cellulose pulp into contact with an alkali metal hydroxide solution to obtain alkali cellulose; reacting the alkali cellulose with an alkylating agent to obtain a reaction product mixture; and subjecting the reaction product mixture to purification to obtain the cellulose ether.
    Type: Grant
    Filed: March 13, 2018
    Date of Patent: June 21, 2022
    Inventors: Shintaro Matsusue, Akira Kitamura, Mitsuhiro Yoshida, Mitsuo Narita
  • Patent number: 11345785
    Abstract: The present disclosure discloses a processing method for intelligent hydrogel from nano-scale starch particles, and belongs to the technical field of nutritional health food. The present disclosure uses dendritic water-soluble starch particles as a skeleton and utilizes a transglycosidation and chain extension-glycan entanglement reaction of glycosyltransferase to obtain an intelligent hydrogel having a spatial reticular structure. The product provided by the present disclosure is an intelligent starch-based hydrogel which has good rehydration capability, biocompatibility, strong gel strength, enzymatic response irreversibility, pH response reversibility, can carry multiple nutritional factors. The hydrogel provided by the present disclosure can protect and control the release of food functional factors, and can be applied to food, biological drug loading, functional materials and the like.
    Type: Grant
    Filed: October 15, 2019
    Date of Patent: May 31, 2022
    Inventors: Ming Miao, Bo Jiang, Yang Qi, Yao Liu, Tao Zhang, Zhengyu Jin
  • Patent number: 11312789
    Abstract: Provided is a process for reducing the size of ethylcellulose polymer particles comprising (a) providing a slurry comprising (i) water (ii) said ethylcellulose particles, wherein said ethylcellulose polymer particles have D50 of 100 ?m or less; (iii) surfactant comprising 1.2% or more anionic surfactants by weight based on the solid weight of said slurry, with the proviso that if the amount of anionic surfactant is 2.5% or less by weight based on the solid weight of said slurry, then said surfactant further comprises 5% or more stabilizers by weight based on the solid weight of said slurry, wherein said stabilizer is selected from the group consisting of water-soluble polymers, water-soluble fatty alcohols, and mixtures thereof. (b) grinding said slurry in an agitated media mill having a collection of media particles having a median particle size of 550 ?m or smaller. Also provided is a dispersion made by such a process.
    Type: Grant
    Filed: December 10, 2015
    Date of Patent: April 26, 2022
    Inventors: Jorg Theuerkauf, Robert B. Appell, Peter E. Pierini, Christopher J. Tucker
  • Patent number: 11299557
    Abstract: Provided is a method of stably producing a water-soluble nonionic cellulose ether powder having a high bulk density at low cost by adding a minimum amount of water. More specifically provided is a method for producing a water-soluble nonionic cellulose ether powder, comprising the steps of: reacting alkali cellulose with an etherifying agent to obtain a reaction product; washing and draining the reaction product to obtain a water-soluble nonionic cellulose ether; mixing the water-soluble nonionic cellulose ether with such an amount of water of 70° C. or higher as to make a water content of the water-soluble nonionic cellulose ether become 55 to 90% by weight to obtain a water-containing water-soluble nonionic cellulose ether having a water content of 55 to 90% by weight; cooling the water-containing water-soluble nonionic cellulose ether; and drying and pulverizing the cooled water-containing water-soluble nonionic cellulose ether.
    Type: Grant
    Filed: March 29, 2017
    Date of Patent: April 12, 2022
    Assignee: Shin-Etsu Chemical Co., Ltd.
    Inventor: Mitsuo Narita
  • Patent number: 11246937
    Abstract: The application of a highly controlled, micron-sized, branched, porous architecture to enhance the handling properties and degradation rate of hydrogels is described in the instant invention. A previously described pattern created through one-step nucleated crystallization in a hydrogel film creates tunable mechanical properties and/or chemical stability for use in tissue engineering applications. The bulk mechanical properties and the degradation rate of the material can be tuned easily by the addition or subtraction of crystalline structure or by the addition and subtraction of backfill material, making this useful for a variety of applications. Relevant mechanical properties that can be tuned through the application of this unique porosity are moduli, elasticity, tensile strength, and compression strength. The method of the present invention can be applied to biopolymers and natural materials as well as synthetic materials.
    Type: Grant
    Filed: March 20, 2019
    Date of Patent: February 15, 2022
    Inventors: Sarah Mayes, Christine Schmidt
  • Patent number: 11229859
    Abstract: A method of recovering a bead support from an emulsion includes supplying an aqueous surfactant solution into a centrifuge tube; supplying a hydrophobic liquid over the surfactant solution in the centrifuge tube, wherein a ratio of the volume of the aqueous surfactant solution to the volume of the hydrophobic liquid is not greater than 0.5; and applying an emulsion over the hydrophobic liquid while centrifuging, the emulsion comprising a dispersed aqueous phase including the bead support, the emulsion breaking and material of the dispersed phase preferentially partitioning to the surfactant solution.
    Type: Grant
    Filed: February 10, 2020
    Date of Patent: January 25, 2022
    Assignee: Life Technologies Corporation
    Inventors: Brian Reed, James A. Ball
  • Patent number: 11229721
    Abstract: The invention includes chitosan nanofibers having enhanced structural integrity, compositions comprising such chitosan nanofibers, and related methods of use. In a particular aspect, electrospun chitosan nanofibers can be reversibly acylated to enhance structural integrity and promote healing and the formation of tissues in a subject. In another aspect, electrospun chitosan nanofibers comprising at least a portion of the amino groups protected, such as through N-tert-butoxycarbonyl groups, demonstrate enhanced structural integrity and promote healing and the formation of tissues in a subject. The invention also includes compositions and methods for producing a modified chitosan material having anti-inflammatory and pro-healing characteristics and methods of using the modified chitosan materials in a film, a gel, a membrane, microfibers, nanofibers, nano- or micro-particles/spheres and/or sponges. In some aspects, microspheres and methods of producing microspheres comprising modified chitosan are included.
    Type: Grant
    Filed: February 27, 2015
    Date of Patent: January 25, 2022
    Inventors: Joel D. Bumgardner, Chaoxi Wu, Hengjie Su, Tomoko Fujiwara, Daniel G. Abebe, Kwei-Yu Liu, Gregory McGraw, Carlos Lee Bumgardner
  • Patent number: 11225529
    Abstract: Disclosed is method for preparation of a starch phosphate using phytate. The method enables the preparation of a starch phosphate with improved physical properties such as high transparency, solubility, swelling power, and storage stability by the phosphorylation of a starch using naturally occurring phytate rather than using a synthetic chemical. Due to these advantages, the starch phosphate is expected to replace conventional chemically modified starches. In addition, the method enables the preparation of a starch phosphate based on a simple modification. The use of the starch phosphate greatly contributes to improvements in the quality and storage stability of various starchy foods. Therefore, the starch phosphate is expected to find application in the food industry, including starchy foods.
    Type: Grant
    Filed: June 24, 2020
    Date of Patent: January 18, 2022
    Assignee: Korea University Research and Business Foundation
    Inventors: Seung-Taik Lim, Eun Young Park
  • Patent number: 11214917
    Abstract: The present invention relates to a method of obtaining a solid material based on a polymer having its cellobiose units exhibiting the following characteristics: at least some of the cellobiose units have at least one carboxylic acid function attached to the C6 carbon, the other C6 carbons having a primary alcohol function attached thereto; and at least some of the cellobiose units have at least one of the two rings open between the C2 and C3 carbons, the other C2 and C3 carbons forming a ring and having an alcohol function attached thereto. Such a material, advantageously a textile, may be used as a compress.
    Type: Grant
    Filed: July 10, 2019
    Date of Patent: January 4, 2022
    Assignee: SYMATESE
    Inventors: Vithuy Dao, Robert Michelot, Benjamin Herbage, Fabien Fuchez, Eric Perouse
  • Patent number: 11198702
    Abstract: A method for separating hydrolysis product of biomass is provided. The method includes providing a mixture solution containing a hydrolysis product of biomass and a divalent metal salt, adjusting the pH value of the mixture solution to between 1-4.6, and performing a filtering procedure on the mixture solution using a nanofiltration membrane to obtain a concentrated solution and a filtrate, wherein the concentrated solution mainly includes the hydrolysis product of biomass and the filtrate mainly includes the divalent metal salt.
    Type: Grant
    Filed: February 3, 2017
    Date of Patent: December 14, 2021
    Inventors: Yen-Ting Kuo, Hou-Peng Wan, Tzu-Yueh Yang, Chien-Yuan Su, Ming-Hua Wang
  • Patent number: 11197885
    Abstract: Described herein are materials and methods useful for the treatment of neurodegenerative disorders and bone disorders, as well as healing wounds, in a subject. Materials described herein include polysaccharide digestive products resulting from the enzymatic hydrolysis of low acyl gellan gum. Also described herein are pharmaceutical compositions comprising one or more of such materials, and methods for their preparation and use.
    Type: Grant
    Filed: March 2, 2017
    Date of Patent: December 14, 2021
    Assignee: The University of Toledo
    Inventors: Joshua J. Park, Dong-Shik Kim
  • Patent number: 11191728
    Abstract: A method of preparing degradable and environment responsive composite microgels, belonging to polymer material synthesis and biomaterial technology fields. Firstly, a copolymer of L-malic acid and 6-hydroxyhexanoate is prepared; then, N,N,N?,N?-tetramethyl cystamine is prepared. The copolymer and N,N,N?,N?-tetramethyl cystamine are mixed in an organic solvent to form a mixed solution which is added into excess distilled water to produce composite microgels. The microgels have advantages of mild preparing conditions, fast reaction speed without catalysts, no impurity remained, and controllable degradation rate. The microgels can load anticancer drug doxorubicin hydrochloride, showing environment responsive controlled release due to introduction of carboxyl groups and disulfide bonds.
    Type: Grant
    Filed: July 14, 2020
    Date of Patent: December 7, 2021
    Inventors: Caihua Ni, Zhenle Tian, Gang Wang, Liping Zhang, Ren Liu
  • Patent number: 11161917
    Abstract: A method for producing a cellulose derivative, including reacting a mixed acid anhydride having two particular types of acyl groups with cellulose in the presence of a base catalyst in an organic solvent having an electron pair-donating property to form a cellulose derivative with the two types of acyl groups derived from the mixed acid anhydride, the acyl groups being introduced at hydroxy groups in the cellulose.
    Type: Grant
    Filed: October 15, 2018
    Date of Patent: November 2, 2021
    Inventors: Shukichi Tanaka, Kiyohiko Toyama, Masatoshi Iji
  • Patent number: 11155642
    Abstract: Provided is a method for producing a cellulose derivative. The method includes forming a first reaction product by reacting non-oxidized cellulose with at least one first alkalization agent in the presence of at least one suitable solvent, wherein the first reaction product includes a non-oxidized alkali-cellulose. The method further includes forming a second reaction product by reacting a monohalo-organic compound with a second alkalization agent in a solution, wherein the second reaction product includes a saturated solution and a sediment. The method further includes increasing a temperature of the saturated solution and dissolving at least a portion of the sediment, and reacting the non-oxidized alkali-cellulose with the second reaction product to form an improved carboxymethyl cellulose.
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: October 26, 2021
    Inventors: Shani Eliyahu-Gross, Yuval Yaskil
  • Patent number: 11136414
    Abstract: The present application discloses regioselectively substituted cellulose esters, films made from the regioselectively substituted cellulose esters and methods for making the same. The regioselectively substituted cellulose esters are synthesized using trifluoroacetic anhydride and cellulose with various acyl donors or acyl donor precursors.
    Type: Grant
    Filed: March 28, 2018
    Date of Patent: October 5, 2021
    Assignee: Eastman Chemical Company
    Inventors: Casey Lynn Elkins, Robert Lin, Michael John Rodig, Robert Jacks Sharpe
  • Patent number: 11053323
    Abstract: A process for dissolving modified cellulose includes contacting modified cellulose solution with at least one multivalent cation to form a plurality of modified cellulose particles.
    Type: Grant
    Filed: November 7, 2016
    Date of Patent: July 6, 2021
    Assignee: Covidien LP
    Inventors: Phillip Blaskovich, Valentino Tramontano, Rachit Ohri, Joshua Kennedy, Christopher M. Henry
  • Patent number: 11046788
    Abstract: A method for controlling the catalytic oxidation of cellulose includes using a heterocyclic nitroxyl compound as catalyst; oxidizing cellulose in a reaction mixture comprising liquid medium, the catalyst and hypochlorite as main oxidant; analyzing one or more oxidative chlorine species dependent on the hypochlorite concentration of the reaction mixture on line in the reaction mixture or in a gas composition which is in contact with the reaction mixture; and controlling supply of hypochlorite to the reaction mixture on the basis of the analysis.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: June 29, 2021
    Inventors: Isko Kajanto, Markus Nuopponen
  • Patent number: 11014993
    Abstract: The present application relates to cellulose nanocrystals and other anionic carbohydrates and methods of preparation thereof. Specifically, in certain embodiments, the cellulose nanocrystals are modified using ion exchange technology to yield thermally stable or task-specific, dispersible cellulose nanocrystals.
    Type: Grant
    Filed: August 5, 2016
    Date of Patent: May 25, 2021
    Inventor: Douglas Fox
  • Patent number: 11008356
    Abstract: The invention relates to lipochitooligosaccharides obtainable from arbuscular mycorrhizal fungi, and which are useful for stimulating arbuscular mycorrhizal symbiosis, and lateral root formation.
    Type: Grant
    Filed: January 25, 2016
    Date of Patent: May 18, 2021
    Assignees: Institut National de Recherche Pour l'Agriculture, l'Alimentation et Environnement, Centre National de la Recherche Scientifique, Universite Paul Sabatier
    Inventors: Jean Denarie, Fabienne Maillet, Verena Poinsot, Olivier Andre, Guillaume Becard, Monique Gueunier, Laurence Cromer, Alexandra Haouy, Delphine Giraudet
  • Patent number: 10982012
    Abstract: A process for dissolving modified cellulose is disclosed. The process includes contacting modified cellulose with a solvent in a mixture to form swelled modified cellulose and then contacting the mixture with a salt to dissolve the swelled modified cellulose.
    Type: Grant
    Filed: November 17, 2016
    Date of Patent: April 20, 2021
    Assignee: Covidien LP
    Inventors: Valentino J. Tramontano, Joshua Kennedy, Sajida Farooqi, Phillip D. Blaskovich, Rachit Ohri, Daniel S. Costa