Abstract: A pixel includes a detector that changes its operating characteristics based on incident energy, an integration capacitor arranged to discharge stored charge through the detector based on changes in the operating characteristics, and an floating gate injection device disposed between the photo-diode and the integration capacitor that controls flow of the charge from the integration capacitor to the detector. The floating gate injection device has a gate, a source electrically coupled to the detector at a first node, and a drain electrically coupled to the integration capacitor. The gate has a control voltage (VT) stored therein to set to a per-pixel bias gate voltage to control a detector bias voltage of the detector at the first node.

Abstract: Provided is a radiation imaging system configured to synchronize radiation irradiation with operation of a radiation imaging apparatus. The radiation imaging system includes: an irradiation unit arranged to irradiate with radiation; a detection unit arranged to detect the radiation; a setting unit configured to set an irradiation time at which irradiation of the radiation is to be started; an irradiation control unit configured to control the irradiation unit so that radiation irradiation is executed at the irradiation time; and a detection control unit configured to control the detection unit so that the detection unit is ready to detect the radiation at the irradiation time.

Abstract: A method for measuring optical signal detector performance that includes directing light emitted from an optical signal detector onto a first non-fluorescent surface portion in a first detection zone of the optical signal detector. A first characteristic of light detected by a first sensor of the first optical signal detector is measured while the first non-fluorescent surface portion is in the first detection zone of the optical signal detector. Light emitted from the optical signal detector is directed into a first void in the first detection zone of the optical signal detector. A second characteristic of light detected by the first sensor of the optical signal detector is measured while the first void is in the first detection zone of the optical signal detector. And an operational performance status of the optical signal detector is determined based on at least one of the first characteristic and the second characteristic.

Abstract: A method of obtaining a quantum efficiency distribution in a predetermined sample surface, including: irradiating a reference material with excitation light belonging to a first wavelength range; obtaining the reference material's image, which includes a first channel for the first wavelength range and a second channel for a second wavelength range, the first and the second channel's irradiation luminance value in each pixel; irradiating the predetermined sample surface with the excitation light; obtaining the first and the second channel's measurement luminance value in each pixel of the image of the predetermined surface; calculating an absorption luminance value from a difference between the first channel's irradiation luminance value and measurement luminance value; calculating a fluorescence luminance value from difference between the second channel's irradiation luminance value and measurement luminance value; calculating quantum efficiency of each pixel based on the values; and obtaining quantum effici

Abstract: An ultra-small thermal imaging core, or micro-core. The design of the micro-core may include substrates for mounting optics and electronic connectors that are thermally matched to the imaging Focal Plane Array (FPA). Test fixtures for test and adjustment that allow for operation and image acquisition of multiple cores may also be provided. Tooling may be included to position the optics to set the core focus, either by moving the lens and lens holder as one or by pushing and/or pulling the lens against a lens positioning element within the lens holder, while observing a scene. Test procedures and fixtures that allow for full temperature calibration of each individual core, as well as providing data useful for uniformity correction during operation may also be included as part of the test and manufacture of the core.

Abstract: A method for ion based radiation therapy treatment planning for avoiding dose delivery to a distal risk organ, said risk organ being located after the target seen from a first beam angle, the method comprising defining an optimization function comprising at least one objective function related to at least one desired property of the treatment plan, wherein the objective function is related to limiting a parameter ? defining the fraction of the total number ?OAR of ions that reach the risk organ relative to the total number ?a of ions. In addition, one can assume a different density when calculating ? which will result in a plan that is more robust with respect to density perturbations.

Abstract: The present invention generally relates to fluorescent marking compositions and their use to determine whether a surface has been cleaned. More particularly, the marking compositions comprise fluorescent polymers.

Abstract: The present specification describes a system for synchronizing a transmission detector and a backscatter detector integrated with a portable X-ray scanner. The system includes a transmitter connected with the transmission detector for transmitting the analog detector signal and a receiver connected with the scanner for receiving the transmitted analog detected signal where the transmitter and the receiver operate in the ultra-high frequency range.

Abstract: A data collection device includes a housing and a data collection unit located in the housing. A power unit is located in the housing and is operably connected to the data unit to provide power for operation of the data unit. An irradiation sensor is located at the data collection device to detect exposure of the data collection device to irradiation. An irradiation sensor includes a thermal energy absorbing material and a thermal energy sensitive material in thermal communication with the thermal energy absorbing material. The thermal energy sensitive material is characterized by a change in color when exposed to a selected degree of thermal energy due to irradiation.

Abstract: Provided is a fluorescence reader that uses two excitation channels and can read up to seven different fluorescent dyes in a single run. Each excitation channel has one light source and one single excitation filter and one dichroic mirror. One excitation channel is capable of exciting multiple fluorescent dyes and can be used to distinguish multiple dyes in combination with multiple emission filters. The excitation channels are driven by a motor that can automatically switch the two excitation channels for taking images of up to seven different fluorescent dyes. An algorithm to calibrate the crosstalk between different fluorescent dyes is also provided. Also provided is a method for analyzing digital PCR data using a ratio of two fluorescence emission readings.

Abstract: An infrared (IR) imaging system for determining a concentration of a target species in an object is disclosed. The imaging system can include an optical system including a focal plane array (FPA) unit behind an optical window. The optical system can have components defining at least two optical channels thereof, said at least two optical channels being spatially and spectrally different from one another. Each of the at least two optical channels can be positioned to transfer IR radiation incident on the optical system towards the optical FPA. The system can include a processing unit containing a processor that can be configured to acquire multispectral optical data representing said target species from the IR radiation received at the optical FPA. One or more of the optical channels may be used in detecting objects on or near the optical window, to avoid false detections of said target species.

Abstract: A device for detecting a contaminant on a scaffolding pole. The device includes an outer detector for detecting a contaminant on an outer surface and an inner detector for detecting a contaminant on an inner surface. The device also includes a mechanism for transporting a scaffolding pole through the device, past the detectors. A contaminant is detected on the outer and inner surfaces of the scaffolding pole using the outer and inner detectors respectively.

Abstract: A system for detecting stimulated emission from a material of interest comprising: an excitation source; and an imaging component; wherein, in use, the system is configured to: a) emit excitation radiation from the excitation source for a first time period, the excitation radiation having a wavelength suitable for inducing stimulated emission in the material of interest; b) capture a first image via the imaging component, the first image substantially consisting of a background illumination component and a stimulated emission component; c) stop emitting excitation radiation for a second time period; d) capture a second image via the imaging component, the second image substantially consisting of the background illumination component; e) create a difference image corresponding to the difference between the first and second images, such that the difference image includes any stimulated emission signals from the material of interest.

Abstract: A tomography method, system, and apparatus based on time-domain spectroscopy are provided. A light emitter is controlled to emit a pulse beam to scan a cross-section of an object to be measured while using a light receiver to detect the pulse beam passing through the object to be measured, so as to obtain time-domain pulse signals at locations of a scan path. A scan angle is repeatedly changed to perform the scanning and detecting steps, so as to collect the time-domain pulse signals of multiple angles of the cross-section as a time information set. Features are retrieved from the time-domain pulse signals using kernels of a trained machine learning model, which is trained with time information sets and corresponding ground truth images of cross-sections to learn the kernels for retrieving the features. The retrieved features are converted into a spatial domain to reconstruct a cross-sectional image of the object.

Abstract: The present invention describes a dosimetry system for use in an irradiation system for radiology or radiotherapy. The dosimetry system comprises an at least two dimensional, radioluminescent, irradiation detection surface comprising radiosensitive material, the radiosensitive material having radioluminescent properties. The system also comprises a detection system configured for detecting radioluminescent radiation from the at least two-dimensional detection surface upon irradiation with a radiology or radiotherapy irradiating beam. The detection system comprises a detector sensitive for radioluminescence and a filter for at least partially blocking radiation from said radiology or radiotherapy irradiating beam and ambient light.

Abstract: Embodiments generally relate to a system for reading fluorescent-labelled diagnostic assays for in-vitro diagnostic applications. The system comprises a receiving member adapted to receive a fluorescent-labelled diagnostic assay cartridge carrying a fluorescent-labelled diagnostic assay; at least one excitation module configured to illuminate the diagnostic assay, when the diagnostic assay cartridge is placed in the receiving member; a camera module for capturing an image of the illuminated diagnostic as—say placed in the receiving member; a processor for receiving the captured image from the camera module and determining whether or not a target analyte was present in the diagnostic assay captured by the camera module; and memory storing firmware, the firmware including a brightness compensation module configured to adjust the intensity of an image of a diagnostic cartridge captured by the camera module, in order to emulate a uniform field of illumination over the diagnostic cartridge.

Abstract: The present invention provides electron beam therapies with improved feedback control that delivers controlled and adjustable doses of electron beam radiation to variable shallow depths with little radiation exposure to both nearby tissues and tissues below the target. In order to control radiation to accurately penetrate to shallow depths and to allow the radiation to be adjusted to other depth settings in very small or even continuous increments, the present invention senses a plurality of different electron beam characteristics and then uses these to derive a composite characteristic, or analog, of the electron beam energy. The composite analog provides a strong correlation to energy that allows this precision. In another aspect, the present invention relates to implementing this feedback control by adjusting power levels used to establish the electron beam.

Abstract: A method for controlling alkali emissions of a glass element during hot forming is provided. The method includes the steps of: heating the glass element using one or more burner units each providing a burner flame to provide a heated glass element; sensing light emissions of a total light emitting area of the heated glass element and the burner flame of the one or more burner units via one or more sensor units; providing one or more signals of the one or more sensor units of the light emissions; comparing the one or more signals with one or more reference signals; determining, based on the comparing step, determined alkali emissions of the glass element; and controlling the one or more burner units based on the determined alkali emissions to adjust the alkali emissions of the glass element to a pre-given interval.

Abstract: A computer software product adapted for use in a weld inspection system is executed by a processor and is stored in an electronic storage medium of the weld inspection system adapted to facilitate the inspection of a weld of a work product. The computer software product includes a first module and a combination module. The first module is configured to transform first and second raw thermal images, associated with respective first and second heat pulses of at least a portion of the work product having the weld, into respective first and second binary images. The combination module is configured to transform the first and second binary images into a combined binary image for the reduction of noise.

Abstract: A fluorescence lifetime measuring apparatus according to an embodiment of the present invention includes: an irradiation light generator configured to generate irradiation light; a fluorescence photon detector configured to irradiate at least one or more samples, containing fluorescent molecules, with the irradiation light and collect a fluorescence photon generated by the irradiation; a converter configured to amplify the fluorescence photon and convert the amplified fluorescence photon into a fluorescence signal; and a measurer configured to analyze data of a function of the fluorescence signal by using a function obtained by multiplying a value, which is obtained by integrating the function of the fluorescence signal, by a simulation function.