Patents Examined by Frederick Wenderoth
  • Patent number: 12710492
    Abstract: A magnetic resonance imaging apparatus according to an embodiment includes a main apparatus and a coil apparatus that is separate from the main apparatus. The main apparatus transmits a wireless signal acquired by frequency-modulating a binary signal based on a first clock signal generated from a first system clock. The coil apparatus generates a second clock signal by dividing the received wireless signal, and generates a second system clock from the generated second clock signal. Frequencies of the second system clock and the first system clock are the same.
    Type: Grant
    Filed: April 22, 2024
    Date of Patent: August 18, 2026
    Assignee: Canon Kabushiki Kaisha
    Inventor: Yu Tanaka
  • Patent number: 12710498
    Abstract: The present disclosure provides a system for MRI. The system may obtain a plurality of echo signals relating to a subject that are excited by an MRI pulse sequence applied to the subject. The system may perform a quantitative measurement on the subject based on the plurality of echo signals. The MRI pulse sequence may include a CEST module configured to selectively excite exchangeable protons or exchangeable molecules in the subject, an RF excitation pulse applied after the CEST module configured to excite a plurality of gradient echoes, and one or more refocusing pulses applied after the RF excitation pulse. Each of the refocusing pulses may be configured to excite one or more spin echoes. The one or more spin echoes excited by at least one of the one or more refocusing pulses may include a symmetric spin echo and one or more asymmetric spin echoes.
    Type: Grant
    Filed: April 17, 2024
    Date of Patent: August 18, 2026
    Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.
    Inventors: Hui Liu, Qi Liu, Yichen Hu
  • Patent number: 12704471
    Abstract: A method for production line nuclear magnetic resonance (NMR) measurement of a fluid comprising a material having a single resonance frequency, the method includes: (a) positioning a reference sample comprising the material and a sample of the fluid within a sensing region of an NMR measurement unit coil of a production line NMR measurement device, and within a magnetic field of a permanent magnet of the production line NMR measurement device, wherein a concentration of the material within the reference sample is of a known value; (b) performing an NMR measurement comprising feeding at least one radio frequency coil of the production line NMR measurement device with a signal having a spectrum that comprises a characteristic frequency of a nucleus of the material, and generating detection signals indicative of sensed radio frequency emissions associated with the reference sample and the sample of the fluid; (c) processing the detection signals to provide an NMR spectrum comprising a first peak associated with
    Type: Grant
    Filed: May 16, 2025
    Date of Patent: August 11, 2026
    Assignee: 4IR Solutions Ltd.
    Inventors: Tal Cohen, Paul J. Giammatteo, Mordechai Bercovici
  • Patent number: 12704574
    Abstract: A magnetic resonance (MR) simulation apparatus according to an embodiment includes processing circuitry. The processing circuitry updates and obtains, for each of voxels, an electron-spin density matrix based on a pulse sequence for acquisition of MR signals. For each of the voxels, the processing circuitry computes, during an acquisition period for the MR signals in the pulse sequence, an observation value representing a predetermined observation by using the density matrix, and computes a spatial partial differential of the observation value based on the pulse sequence. The processing circuitry computes a signal value for output based on the observation value and the spatial partial differential of the observation value. The signal value represents a sum of the MR signals in the voxels.
    Type: Grant
    Filed: August 14, 2024
    Date of Patent: August 11, 2026
    Assignee: Canon Kabushiki Kaisha
    Inventor: Hidenori Takeshima
  • Patent number: 12693357
    Abstract: Embodiments of the present disclosure provides a tuning device for a receiving coil, a cryogenic probe, and a magnetic resonance device. The tuning device may include a fixed capacitor, a varactor assembly, and a control assembly. The fixed capacitor and the coil may be connected in series. The varactor assembly may be connected in parallel to both ends of the fixed capacitor. The control assembly may be configured to control the capacitance of the receiving coil by controlling the capacitance value of the varactor assembly to perform a tuning operation on the receiving coil, the tuning operation including at least one of a frequency tuning and an impedance tuning.
    Type: Grant
    Filed: March 22, 2024
    Date of Patent: July 28, 2026
    Assignee: WUHAN UNITED IMAGING LIFE SCIENCE INSTRUMENT CO., LTD.
    Inventors: Ze Yu, Chuo Xie, Ou Xiong, Hongxia Lei, Weidong Wang
  • Patent number: 12685492
    Abstract: A synchronisation system comprises aa sensor arrangement to detect a trigger base event. An analysis module and an arithmetic unit are configured to access prior information on a time delay between the sensor arrangement's detection of the trigger base and a starting point of an acquisition time interval for acquiring imaging data. The starting point is computed of the acquisition time interval from the detected trigger base event and the prior information of the time delay. The time delay between the sensor arrangement's detection of the trigger base event and the acquisition time interval may vary between individual subjects, but for each individual subject the time delay is well reproducible and hence on a per subject basis may be calibrated for.
    Type: Grant
    Filed: July 11, 2022
    Date of Patent: July 21, 2026
    Assignee: Koninklijke Philips N.V.
    Inventors: Steffen Weiss, Wenjin Wang, Albertus Cornelis Den Brinker, Albert Garcia Tormo
  • Patent number: 12687600
    Abstract: A method for parameterizing a gradient performance of a magnetic resonance imaging system using an electronic computing facility of the magnetic resonance imaging system includes specifying a first limit value for the gradient performance in dependence on potential nerve stimulation of a patient, and specifying a second limit value for the gradient performance in dependence on potential cardiac muscle stimulation of the patient. The method also includes parameterizing a maximum gradient amplitude of a pulse of the gradient performance and a slew rate of the pulse in dependence on the first limit value and the second limit value.
    Type: Grant
    Filed: November 30, 2023
    Date of Patent: July 21, 2026
    Assignee: Siemens Healthineers AG
    Inventors: Dominik Paul, Mario Zeller, Flavio Carinci, Carsten Prinz, Max Müller
  • Patent number: 12663492
    Abstract: Systems and methods are provided for producing diffusion-weighted images of a subject using a magnetic resonance imaging (MRI) system. The method includes performing a stimulated echo preparation module using non-selective radio-frequency (RF) pulses designed to induce a stimulated echo, performing an acquisition module that includes a multi-slice acquisition of MR data in the presence of diffusion gradients, and reconstructing the diffusion-weighted images of the subject from the MR data.
    Type: Grant
    Filed: April 18, 2022
    Date of Patent: June 23, 2026
    Assignee: BETH ISRAEL DEACONESS MEDICAL CENTER, INC.
    Inventor: David Alsop
  • Patent number: 12663490
    Abstract: An MRI coil having embedded therein a Diagnostic Interface Device (or DID); means for plugging the embedded DID of the MRI coil to a frequency-testing power source, said embedded DID adapted for: (a) measuring the status of certain key electrical conditions for the coil; (b) receiving a response back from the signals initially aimed at the coil in question; (c) processing those responses received; and (d) transferring the measured electronic status (using a specific code number for the coil) to a remote storage area on the internet. A method of use is also disclosed.
    Type: Grant
    Filed: June 27, 2022
    Date of Patent: June 23, 2026
    Inventors: Fahad Alraddadi, William Monski, Tobias Sun
  • Patent number: 12656431
    Abstract: A system and method for compensation of radiofrequency (RF) spatial encoding misalignment errors due to gradient non-linearity in magnetic resonance imaging is described. The true magnetic field produced by the gradient coils in space are taken into account in order to encode the appropriate frequency band and offset of the RF pulse corresponding to the desired spatial encoding position and thickness. This method is applicable to any positionally (frequency) encoded radiofrequency (RF) pulses including slice or slab excitation pulses, inversion pulses, spin echo (refocusing) pulses and spatial saturation pulses.
    Type: Grant
    Filed: April 14, 2023
    Date of Patent: June 16, 2026
    Inventors: Chad Tyler Harris, Andrew Thomas Curtis
  • Patent number: 12656426
    Abstract: In an approach to measuring a magnetic field of a sample, a system includes an optical fiber comprising a first end and a second end, the optical fiber having a core; and a nitrogen vacancy (NV) diamond sensor; where the first end of the optical fiber is configured to receive excitation light from an optical excitation source; and the NV diamond sensor is coupled to the second end of the optical fiber with an optical matching material, the optical matching material configured to optically match the NV diamond sensor to the core of the optical fiber.
    Type: Grant
    Filed: January 10, 2024
    Date of Patent: June 16, 2026
    Assignee: Battelle Memorial Institute
    Inventors: Steven M. Risser, Andy F. Kirby, Richard J. Higgins, Anthony F. George
  • Patent number: 12656281
    Abstract: A sensor system is based on diamonds with a high density of NV centers. The description includes a) methods for producing the necessary diamonds of high NV center density, b) characteristics of such diamonds, c) sensing elements for utilizing the fluorescence radiation of such diamonds, d) sensing elements for utilizing the photocurrent of such diamonds, e) systems for evaluating these quantities, f) reduced noise systems for evaluating these systems, g) enclosures for using such systems in automatic placement equipment, h) methods for testing these systems, and i) a musical instrument as an example of an ultimate application of all these devices and methods.
    Type: Grant
    Filed: April 2, 2024
    Date of Patent: June 16, 2026
    Assignee: QUANTUM TECHNOLOGIES GmbH
    Inventors: Jan Berend Meijer, Robert Staacke, Nils Meijer, Bernd Burchard
  • Patent number: 12644939
    Abstract: A resonant power circuit, a magnetic resonance imaging system, and a transformer are provided. The resonant power circuit is disposed within a scan room of a magnetic resonance imaging system, and is used for supplying power to a switch device in a radio-frequency amplifier of the magnetic resonance imaging system. The resonant power circuit includes: an inverter circuit, a resonant transformer circuit, and a rectifier circuit. The ratio of a resonant frequency is greater than 1 and less than a first threshold, a series resonant frequency being determined according to a resonant capacitor and a resonant inductor.
    Type: Grant
    Filed: April 19, 2024
    Date of Patent: June 2, 2026
    Assignee: GE Precision Healthcare LLC
    Inventors: Yanan Chen, Haiyuan Sun, Gang Ma, Tao He, Sun Lu
  • Patent number: 12638533
    Abstract: Exemplary system, method and computer arrangement for determining rotational invariants, fiber orientations, and scalar parameters of fiber tracts (e.g., compartment fractions, which can relate to intra/extra-cellular space volumes; compartment diffusivities; relaxation rates; exchange rates between compartments; characteristics of structural disorder such as axonal beading) from a general diffusion MRI acquisition is described. For example, gradient directions may not necessarily be arranged in so-called shells, and an acquisition may vary spatially. Furthermore, each acquisition can be undersampled in the k-space. A procedure can also be included for receiving information related to the at least one image. Another procedure can be provided for decoupling tissue and protocol parameters based on a singular value decomposition. A further procedure can be provided for grouping singular vectors into multiplets based on symmetries.
    Type: Grant
    Filed: March 31, 2025
    Date of Patent: May 26, 2026
    Assignee: NEW YORK UNIVERSITY
    Inventors: Santiago Coelho, Els Fieremans, Dmitry S. Novikov
  • Patent number: 12638531
    Abstract: A system for RF based frequency encoding utilizing a Bloch-Siegert shift, includes a controller, an RF encoding system, and an injection transformer simultaneous transmit and receive filter. The controller generates RF excitation pulses, RF based frequency encoding pulses, and a cancellation signal. The RF encoding system includes one or more RF coils configured to transmit the RF excitation pulses and RF based frequency encoding pulses, and to receive an MR signal from the subject where the MR signal includes a leakage signal induced by the RF based frequency encoding pulses. The injection transformer simultaneous transmit and receive filter is in signal communication with the controller and the RF encoding system. The injection transformer simultaneous transmit receive filter is configured to receive the cancellation signal, the MR signal including the leakage signal, and to cancel the leakage signal from the received MR signal to generate a filtered MR signal.
    Type: Grant
    Filed: May 15, 2024
    Date of Patent: May 26, 2026
    Assignees: Case Western Reserve University, Vanderbilt University
    Inventors: Sai Abitha Srinivas, William A. Grissom, Mark A. Griswold
  • Patent number: 12638530
    Abstract: In a method for processing fully sampled k-space MRI imaging data associated with a tissue of interest within a FOV, a neural network may be trained using undersampled k-space MRI imaging data associated with the tissue of interest. At least one subset of the fully sampled k-space MRI imaging data may be obtained based on an input dimension of the trained neural network such that a dimension of each one of the at least one subset is the same as the input dimension. Each one of the at least one subset of the fully sampled k-space MRI imaging data may be processed by the trained neural network, respectively. Spatial domain MRI imaging data associated with the tissue of interest within the FOV may be accordingly determined based on corresponding output of the trained neural network.
    Type: Grant
    Filed: July 26, 2023
    Date of Patent: May 26, 2026
    Assignee: Siemens Healthineers AG
    Inventor: Mario Zeller
  • Patent number: 12601804
    Abstract: According to an aspect of the present inventive concept there is provided a method of magnetic resonance (MR) imaging of an object positioned in an examination volume of an MR scanning device, the method comprising: acquiring, by the MR scanning device, multiple parallel, segmented acquisitions from the object, comprising: applying an R2 sensitizing phase; acquiring a first acquisition; applying an R1 sensitizing phase; acquiring a second acquisition; waiting for a delay time; and acquiring a third acquisition; wherein each acquisition comprises measuring at least three echoes at different echo times (TE); calculating multiple physical properties of the object based on at least some of the at least three acquisitions.
    Type: Grant
    Filed: December 13, 2023
    Date of Patent: April 14, 2026
    Assignee: SYNTHETICMR AB (publ)
    Inventor: Marcel Warntjes
  • Patent number: 12593981
    Abstract: A method for determination of an indicator representative of a change in the brain caused by a demyelinating disease, the method including, for each region of interest of the brain, determining a regional coefficient of one of the following diffusion coefficients: the radial diffusion, the axial diffusion, the mean diffusion, the anisotropy fraction, or a combination of several of these coefficients, the regional coefficients being determined from a diffusion MRI image; determining a number of changed regions, for which a condition relating to the value of the regional diffusion coefficient of each region is satisfied; and determining the indicator in accordance with the number of changed regions.
    Type: Grant
    Filed: August 19, 2022
    Date of Patent: April 7, 2026
    Assignee: BRAINTALE
    Inventor: Vincent Perlbarg
  • Patent number: 12596164
    Abstract: A method and a magnetic resonance imaging (MRI) system improve an MRI signal from a magnetization of interest. The method includes performing an MRI pulse sequence containing three consecutive radio frequency (RF) elements, namely, a first element that is an inversion-recovery pulse sequence characterized by a time of inversion, a second element that is an image-encoding pulse sequence starting at the time of inversion with an excitation RF pulse followed by an image-encoding gradient and a data sampling. The second element is followed by a third element. An MRI signal generated by the object and sampled by image readout blocks applied to the object by the MRI system during each repetition time, is acquired. From the MRI signal, an image of the object is reconstructed. The third element is a modified driven-equilibrium (mDE) pulse sequence configured for achieving a conversion of a transverse magnetization component.
    Type: Grant
    Filed: November 30, 2023
    Date of Patent: April 7, 2026
    Assignees: Siemens Healthineers AG, Balgrist Campus AG
    Inventors: Constantin von Deuster, Daniel Nanz
  • Patent number: 12584982
    Abstract: A method for imaging a subject using an MRI system includes determining a plurality of echo times and then acquiring a plurality of variable echo time signals corresponding to the plurality of echo times at a plurality of k-space locations. In the method, a water k-space data signal and a fat k-space data signal is generated for each of the plurality of k-space locations based on the plurality of variable echo time signals corresponding to that k-space location. Finally, the method includes generating a medical image of the subject based on water k-space data signals and fat k-space data signals at the plurality of k-space locations respectively.
    Type: Grant
    Filed: August 31, 2023
    Date of Patent: March 24, 2026
    Assignee: GE Precision Healthcare LLC
    Inventors: Florian Wiesinger, Michael Carl