Abstract: This application is generally related to identifying or otherwise programming one or more cycling parameters for operation of an implantable pulse generator to provide a neurostimulation therapy to a patient using a non-paresthesia stimulation pattern. In some embodiments, the cycling parameter is selected by measuring physiological signals during trial stimulation. In other embodiments, multiple cycling parameters are identified for use by the patient using a patient controller device.

Abstract: An iridocorneal angle of the eye can be opened with a plurality of treatment locations at least about 2 mm radially outward from a limbus of the eye. The opening on the angle can be beneficial for treating both narrow angle glaucoma and open angle glaucoma. The plurality of treatment locations located away from the limbus can decrease invasiveness and complexity of the procedure. The plurality of treatment locations at least about 2 mm away from the limbus can provide tensioning to zonules coupled to the lens of the eye to flatten the lens of the eye, which can allow the iris to move posteriorly so as to open the iridocorneal angle. The plurality of treatment locations may comprise scleral locations, in which shrinkage of scleral tissue at the plurality of treatment locations provides tensioning to the zonules.

Abstract: A device and method for the pre-display of a spot pattern to be applied for a laser treatment of the eye. The spot patterns to be applied are displayed to the operator in advance with the aid of a target beam. The device for the pre-display of a spot pattern to be applied for a laser treatment of the eye includes a laser system and a scanning system for generating a target beam. Here, the laser system and the scanning system for generating the target beam are formed to generate one or more lines which overlie all the spots of the spot pattern of a planned laser treatment. The device and method are suitable for laser treatment of the retina, the trabecular meshwork as well as other regions. Here, it is irrelevant whether what the laser treatment to be applied is.

Abstract: Apparatus and methods are described including a left ventricular assist device. The left ventricular assist device includes an impeller configured to be placed inside a subject's left ventricle, and to pump blood from the subject's left ventricle to the subject's aorta, by rotating. A frame is disposed around the impeller. A tube traverses the subject's aortic valve, such that a proximal portion of the tube is disposed within the subject's aorta and a distal portion of the tube is disposed within the subject's left ventricle. The distal portion of the tube defines one or more blood inlet openings that are configured to allow blood to flow from the subject's left ventricle into the tube. A braided element is configured to prevent inner structures of the left ventricle from passing into the one or more blood inlet openings. Other applications are also described.

Abstract: A safety system for laser treatment, comprising a first sensor configured to monitor a parameter at a source and to generate first parameter data, a second sensor configured to monitor the parameter at a treatment head and to generate second parameter data, a control system configured to receive the first parameter data and the second parameter data and to determine whether the first parameter data or the second parameter data exceed a predetermined value and the control system further configured to modify an operational parameter of the source in response to a determination that the first parameter data or the second parameter data exceed the predetermined value.

Abstract: A method of determining blood pressure measurements includes inflating a cuff, receiving an indication of pressure inside the cuff during inflation, determining a blood pressure based at least in part on the received indication, assigning a confidence level to the blood pressure, and determining whether the confidence level satisfies a threshold confidence level. Based at least on a determination that the confidence level satisfies a threshold confidence level, the method can include causing a display to display the blood pressure. Based at least on a determination that the confidence level does not satisfy a threshold confidence level, the method can include deflating the cuff, receiving an indication of pressure inside the cuff during deflation, determining another blood pressure, and causing a display to display a blood pressure.

Abstract: Wirelessly powered photodynamic therapy devices are disclosed and systems and methods using such devices are also disclosed. In an embodiment, a photodynamic therapy system comprises: an implantable illumination device comprising a light source configured to emit light having a spectrum which overlaps with an absorption peak of an absorption target and a receiver antenna coupled to the light source and configured to extract power from a radiofrequency power signal incident on the implantable illumination device; and a transmitter comprising an antenna, a powering module configured to generate a drive signal which causes the antenna to generate the radiofrequency power signal, and a dosimetry module coupled to the antenna and configured to detect a radiofrequency signal backscattered from the implantable illumination device and determine an indication of the power extracted by the implantable illumination device from the radiofrequency signal backscattered from the implantable illumination device.

Abstract: A method for controlling charging a power source of an implantable medical device (IMD) in a patient including determining a power being delivered to a primary coil of an external charging device for recharging, determining an estimated power delivered to the IMD power source an estimated heat generated by the primary coil based on a resistance of the primary coil determined as function of at least one of a recharge frequency, a temperature of the primary coil, and a current supplied to the primary coil, calculating an estimated heat generated by the IMD by subtracting the estimated heat generated by the primary coil and the estimated power delivered stored by the rechargeable power source from the power being delivered to a primary coil; and controlling based on the heat generated by the IMD, the power being delivered by the primary coil of the external charging device.

Abstract: An auscultatory sound-or-vibration sensor electronic test signal applied to a sound generator generates an acoustic sound signal, responsive to which an auscultatory sound-or-vibration sensor in proximity to the sound generator generates a corresponding auscultatory sound signal. The auscultatory sound-or-vibration sensor electronic test signal incorporates a plurality of frequency components, each frequency component of which incorporates an integral number of wavelengths and is terminated following a duration of time corresponding to the integral number of wavelengths after that frequency component is applied to the corresponding sound generator. A determination of whether or not the auscultatory sound-or-vibration sensor is functioning properly is made responsive to an analysis of a Fourier Transform of the auscultatory sound signal.

Abstract: Methods are disclosed for reduction of muscle fatigue, enhancement of wound healing and tissue repair and/or reduction of pain. The methods comprise irradiating a muscle or an injured tissue of a subject, as applicable, with pulsed blue and/or red light having an average irradiance that ranges from 0.1 mW/cm2 to 20 mW/cm2 at a radiant exposure that ranges from 0.5 J/cm2 to 60 J/cm2. The pulsed blue and/or red light is preferably applied with a flexible light source that includes a flexible light emitter positioned between a flexible anode and a flexible cathode. The flexible light emitter may comprise a printed LED film or OLEDs that emit blue and/or red light, or a printed LED film or OLEDs that emit blue light in combination with a quantum dot film that converts a portion of the blue light emission into red light.

Abstract: A percutaneous lead is provided which includes a generally tubular, multi-duct, flexible lead body. The lead body supports a distal set of electrodes and a proximal set of contacts which are connected by conductors in the ducts. The lead body further houses an optical fiber with a side firing section. The side firing section is held adjacent an optical transmission window, integrally formed with the flexible lead body. A cylindrical ferrule is provided to position the fiber in the header of an IPG.

Abstract: A therapeutic device having a first removable pack having a first temperature, a second removable pack having a second temperature, a flexible receptacle having a first compartment and a pocket. The first compartment of the flexible receptacle is configured to receive the first removable pack. The pocket is connected to the outer wall surface of the flexible receptacle and forms a second compartment configured to receive the second removable pack through a first opening of the pocket. The therapeutic device combines both hot and cold therapy to work simultaneously together. The application of both hot and cold to the site of an injury of a user stimulates blood circulation to an injured muscle with heat and reduces inflammation with cold to facilitate a faster and more efficient recovery process of the afflicted area.

Abstract: Closed-loop transcranial stimulation and monitoring is disclosed that includes generating a stimulation signal having a set of first oscillation parameters; applying the stimulation signal transcranially to a patient; monitoring the stimulation signal as applied to the patient; receiving a brain activity signal from the patient; generating a feedback signal based on the monitored stimulation signal as applied to the patient; and generating a modified activity signal by subtracting the feedback signal from the brain activity signal; determining one or more second oscillation parameters of the modified activity signal; and adjusting the set of first oscillation parameters of the stimulation signal based on the one or more second oscillation parameters of the modified activity signal. Closed-loop transcranial stimulation and monitoring is also disclosed in which the patient is engaged in a cognitive task.

Abstract: Provided is a device useful for facial beauty treatment by efficiently releasing ligaments, SMAS fascia, and the like, and having a compact structure with multiple functions and an ease for a user to use at home. The present invention provides a device (1) that has a massage function by rolling of a roller (3), a suction function by a suction portion (4), and a stimulation function by outputting a stimulation signal by a conductive element (34) fixed to a bottom surface (23) or a roller (3), and can efficiently and reliably implement an effect such as releasing the ligaments such as a facial skin of a user. In addition, since a circumferential protrusion (61) is formed on the peripheral edge of an opening portion (24) for performing suction so as to surround the opening portion (24), it is possible to enhance confidentiality during suction by the suction portion (4), and the effect described above can be efficiently exhibited.

Abstract: Device and method for an interactive skin device for monitoring physical parameters of a body of a living thing. The interactive skin device may be positioned in or proximate to the skin of the living thing. The interactive skin device may monitor at least one physical parameter generated by an implanted medical device. The interactive device may include a flexible display layer, a cover layer, and a control circuit. The control circuit may be configured to control operation of the flexible display layer. The interactive skin device may trigger an alert when the at least one monitored physical parameter deviates from a predetermined threshold. The implanted medical device may be electrically connected to the interactive skin device by wireless, wired, optical, or combination electrical circuitry. In one embodiment, one or more ECG acquisition devices implanted into a human provide ECG data to an interactive skin device or external computing device.

Abstract: A light treatment device includes a stacked structure for applying a light treatment to a patient's skin. The stacked structure includes a light source configured to emit treatment light, and a light diffusing layer. The light diffusing layer is configured to receive the emitted treatment light, diffuse the treatment light, and output diffused treatment light.

Abstract: In some examples, a method for controlling delivery of cardiac therapy and cardiac sensing by a medical device system including electrodes for delivering the cardiac therapy may include storing, in a memory of the medical device system, a respective value for each of a plurality of cardiac therapy and/or sensing parameters and, in association with each of a plurality of heart position states, a respective modification of at least one of the cardiac therapy and/or sensing parameters. Such a method also may include determining a current one of the plurality of heart position states of the patient, modifying the at least one cardiac therapy and/or sensing parameter value according to the modification associated with the current heart position state, and controlling the delivery of the cardiac therapy and/or cardiac sensing according to the modified at least one cardiac therapy and/or sensing parameter value.

Abstract: A method and apparatus for transdermally providing electrical current to a region of a user's head at high impedance conditions, while maintaining low voltage levels.

Abstract: Systems and methods for detecting heart sound information from a subject's head are described. A system embodiment includes a headgear to be worn on the subject's head, and first and second sensors to sense respectively first and second physiologic signals each representing vibration, motion, or displacement conducted through patient body tissue. The sensed physiologic signals contain heart sound information. At least one of the first or the second sensor is included in the headgear, and placed at a head location to sense a physiologic signal indicative of heart sounds. The system includes a processor to generate a composite signal using the sensed first and second physiologic signals. The system may generate a heart sound metric using the composite signal, and detect a cardiac event such as an arrhythmia or worsening heart failure.

Abstract: The invention provides medical or industrial light source devices, for example, an endoscope. A light source device includes: a light source emitting a light beam; a concentrator including a pair of Fresnel lenses with corrugated surfaces and concentrating the emitted light beam, the corrugated surfaces of the Fresnel lenses facing each other, and a light guide guiding the concentrated light beam. The corrugated surfaces of the pair of Fresnel lenses may be in contact with each other and one end of the light guide may be disposed at a focal point of the concentrated light beam.