Abstract: In a laser cataract procedure that also corrects for astigmatism, an iris registration method compares an iris image of a patient's eye taken when the eye is not docked to a patient interface device with an iris image of the same eye that is docked to the patient interface, to calculate a rotation angle between the two images. The astigmatism axis of the eye is measured when the eye is not docked, and the measured axis is rotated by the calculated rotation angle to obtain a rotated astigmatism axis relative to the iris image of the docked eye. The laser cataract procedure is performed based on the rotated astigmatism axis. The rotation angle is calculated by optimizing a transformation that transforms the undocked iris image to match the docked iris image, where the transformation includes a dilation factor that accounts for different pupil dilation of the two iris images.

Abstract: An implantable vagus nerve stimulation (VNS) system includes a sensor configured to measure ECG data for a patient, a stimulation subsystem configured to deliver VNS to the patient, and a control system configured to perform a heart rate variability analysis with the ECG data. In some aspects, performing the heart rate variability analysis includes measuring R-R intervals between successive R-waves for the ECG data measured during a stimulation period and a baseline period, plotting each R-R interval against an immediately preceding R-R interval for each of the stimulation period and the baseline period, and determining at least one of a standard deviation from an axis of a line perpendicular to an identity line for each of the stimulation period plot and the baseline period plot or a centroid of each of the stimulation period plot and the baseline period plot.

Abstract: An optical probe includes: an optical fiber; a reflecting portion; and a traveling direction changing portion changing a traveling direction of a laser beam of a first wavelength that has transmitted through the reflecting portion to a direction different from a traveling direction before transmitting through the reflecting portion. Further, the traveling direction changing portion is configured by a bending structure having a structure in which a portion on a distal end side of the optical fiber is bent, and the reflecting portion is provided closer to a proximal end side of the optical fiber than the bending structure.

Abstract: A system and method for identifying sleep states of a subject are provided. In some aspects, the method includes acquiring physiological data from a subject over a sleep period using sensors positioned about the subject, and assembling the physiological data into time-series datasets. The method also includes selecting a temporal window in which signals associated with the time-series datasets are substantially stationary, computing a time bandwidth product based on a selected spectral resolution and the selected temporal window, and determining a number of tapers using the computed time bandwidth product. The method further includes computing a spectrogram using the determined number of tapers and the time-series datasets, analyzing the spectrogram to identify signatures of sleep in the subject, and generating, using the identified signatures, a report indicative of sleep states of the subject.

Abstract: A shape compliant wearable Photo-Dynamic Therapy (PDT) pad comprises an outer layer having an outer surface adapted to be exposed to the ambient, an inner layer having an inner surface adapted to be in contact with a body of a user, a metallic sheet provided between the outer layer and the inner layer, the metallic sheet being shape compliant, and a plurality of Light Emitting Diodes (LEDs) provided between the inner layer and the outer layer. The plurality of LEDs is configured to emit electromagnetic radiation towards the body of the user. Also, the inner layer and the metallic sheet include an enclosed cavity therebetween, the metallic sheet is configured to be maintained at a negative potential, and the inner layer includes a plurality of air holes providing a passage for ambient air to enter and exit the enclosed cavity.

Abstract: The invention relates to a spirometer (1) comprising a MEMS-based thermal fluid flow sensor (13, 13.1, 13.2) for generating a signal in response to a fluid flow generated during inhalation or exhalation; and a microcontroller (14) for calculating the fluid flow from the signal generated by the flow sensor (13, 13.1, 13.2). The spirometer (1) may be connected to other devices, such as a smartphone or a personal computer or any other computing unit which is adapted to collect, store, analyse, exchange and/or display data. The invention further describes the use of the spirometer (1) in measuring a user's lung performance and/or monitoring it over time.

Abstract: The present application provides an endoscopic device having at least one shaft, which has at least one portion deflectable in at least one plane, and having at least one deflection mechanism, which is configured to deflect the deflectable portion and includes, arranged in series, at least one first connection member and at least one second connection member interacting for a deflection with the first connection member. The first connection member is formed at least partially from a first material, and the second connection member is formed at least partially from a second material, of which the elasticity differs from that of the first material.

Abstract: A medical instrument system includes actuators, a medical instrument, and a control system operably connected to the actuators. The medical instrument includes an end portion and transmission systems, each of which couples the end portion to an actuator of the actuators such that the actuators are operable to drive the transmission systems to move the end portion. The control system is configured to execute operations including determining a difference between a current configuration of the end portion and a desired configuration of the end portion, and operating the actuators to apply tensions to the transmission systems based on the difference and based on constant offset tensions. The constant offset tensions are independent of current tensions experienced by the transmission systems.

Abstract: A welded structure, in which a second tubular member is welded to an inner circumference of a first tubular member made of metal, the second tubular member being made of metal and having an outer diameter smaller than an inner diameter of the first tubular member, includes welded portions at which a portion of the first tubular member and a portion of the second tubular member are melted and solidified, a surface melted and solidified from an inner circumferential surface side of the first tubular member toward an end surface of the second tubular member forms a smoothly-continuous curved surface, and the first and the second tubular members are bonded to each other. A portion of each of the welded portions is located on an outside of a projection region obtained by projecting the second tubular member onto an outer surface of the first tubular member.

Abstract: A method for providing personalized health assessment of a subject includes: receiving a raw electrocardiography (ECG) signal of a subject from an ECG device and a raw blood pressure (BP) signal of the subject from a BP waveform detector; calculating a beat-to-beat ECG signal from the raw ECG signal; calculating a beat-to-beat BP signal from the raw BP signal; calculating a beat-to-beat pulse arrival time (PAT) signal that is measured as a time delay between the beat-to-beat ECG signal and the beat-to-beat BP signal; calculating an interpolated beat-to-beat PAT signal and an interpolated beat-to-beat BP signal by interpolating the beat-to-beat PAT signal and the beat-to-beat BP signal, respectively; assessing a subject-specific relationship between the interpolated beat-to-beat PAT signal and the interpolated beat-to-beat BP signal; and estimating a real-time blood pressure of the subject based on the subject-specific relationship.

Abstract: Disclosed is a plasma skin care device including a handpiece, an ozone decomposition module, and a suction fan. The handpiece has a plasma generator and discharges plasma in a state in which a front end portion of the plasma generator is adjacent to skin. The ozone decomposition module is configured to receive and decompose ozone, which is generated when the plasma is discharged, from the handpiece. The suction fan is configured to draw the ozone generated in the handpiece to the ozone decomposition module by suction pressure.

Abstract: A method for emitting laser light in the form of laser pulses, including the steps: planning a laser pulse based on pulse parameters, checking whether laser pulses which were emitted within a predefined preceding time interval, together with the planned pulse, meet a predefined energy criterion, and emitting the planned laser pulse with the aid of an emitting unit if the energy criterion is met, and not emitting the planned laser pulse or reducing a power of the laser pulse if the energy criterion is not met.

Abstract: A system and method are provided for monitoring subject behavior during sleep onset. In some aspects, a system includes one or more sensors configured to acquire behavioral data from a subject using input provided during sleep onset. The system also includes a processor programmed to at least assemble a time-series of behavioral responses using the behavioral data acquired using the one or more sensors, and estimate an instantaneous probability of response using the time-series of behavioral responses. The processor is also programmed to generate a statistical model of wakefulness using the instantaneous probability of response, and estimate, using the model, a probability indicative of a degree to which the subject is awake at each point in time during the sleep onset process. The processor is further configured to generate a report indicative of sleep onset in the subject. The system also includes an output for displaying the report.

Abstract: An electronic device for providing exercise information and a method therefor are provided. The electronic device includes a first sensor module, a second sensor module, at least one output device, and at least one processor. The at least one processor is configured to detect an event relating to start of an exercise state, obtain motion information corresponding to the exercise state using the first sensor module, obtain metabolite information of a user using the second sensor module, and provide information regarding the exercise state to the user through the at least one output device, based on whether the metabolite information satisfies a specified condition.

Abstract: A surgical apparatus comprising: a mechanism that is configured to perform an operational motion of the surgical apparatus; and at least one transformation member having an original shape and a deformed shape, the at least one transformation member connecting the mechanism together, when the at least one transformation member is in the deformed shape so that the mechanism is capable of performing the operational motion; and wherein after the transformation member is subject a transition temperature, the at least one transformation member changes from the deformed shape to the original shape and disengages a portion of the mechanism so that the mechanism is prevented from performing the operational motion.

Abstract: The disclosure relates to an actuation unit (16) for a medical instrument (10) and to a medical instrument (10) with a shaft (12) which extends between a proximal end (20) and a distal end (22), wherein the instrument (10) is designed at the distal end (22) to receive an end effector (14), an actuation unit (16, 216) which is assigned to the proximal end of the shaft (12), and which has a plurality of drives (50, 52, 54, 56), and with at least two control trains (100, 102, 104, 106, 108, 110, 112, 114) which extend through the shaft (12), wherein the at least two control trains (100, 102, 104, 106, 108, 110, 112, 114) can be used for controlling at least one degree of freedom of the instrument, in particular for deflecting the end effector (14), wherein the at least two control trains (100, 102, 104, 106, 108, 110, 112, 114) comprise a first control train (100, 104, 108, 112) and a second control train (102, 106, 110, 114), and wherein the first control train (100, 104, 108, 112) is coupled to a first carrier

Abstract: A patchable biosensor includes a substrate extending in a longitudinal direction and being stretchable for being patched to a surface of a living body and an electronic component disposed on a one-side surface in a thickness direction of the substrate and extending in the longitudinal direction. The longitudinal direction of the electronic component crosses the longitudinal direction of the substrate.

Abstract: An electrocardiogram waveform measurement system is configured to be suitable for measuring an electrocardiogram waveform with high precision using multiple electrodes provided to an article of clothing. A measurement unit performs measurement in a state in which multiple fabric electrodes are grouped into multiple channels. A signal measured by the electrodes for each channel is evaluated in a two-dimensional manner based on the number of times an R wave is detected by an R wave processing unit in a predetermined period of time and a degree of data concentration in a dynamic range acquired by a degree-of-concentration calculation unit. A channel selection unit selects the optimum channel.

Abstract: This invention is directed to a medical device having an elongate shaft having a distal end and a controller coupled to the shaft. A control member can extend through at least part of the elongate shaft and at least part of the controller, wherein the control member in a tensioned configuration can be moveable by the controller to control the distal end of the shaft and the control member can be slack in an untensioned configuration. A tensioning mechanism can be configured to move relative to at least one of the elongate shaft and the controller to tension the control member and automatically lock the control member in the tensioned configuration.

Abstract: A biological signal analysis device includes: an acquiring unit configured to acquire biological signals of a measurement target; a trigger information acquiring unit configured to acquire, from a stimulator configured to apply stimuli to the measurement target, trigger information indicating times at which the stimuli are generated; and a signal processing unit configured to process the biological signals. The signal processing unit is configured to calculate biological information on the measurement target based on the biological signals, maintain only pieces of trigger information corresponding to times at which it is determined that biological signals of the measurement target are generated, from the calculated biological information, delete another piece of trigger information, and use an averaged waveform that is obtained by performing an averaging process on the biological signals that are generated in synchronization with the stimuli based on the pieces of remaining trigger information.