Abstract: The present invention generally relates to the transdermal delivery of various compositions. In some aspects, the transdermal delivery may be facilitated by the use of a hostile biophysical environment. One set of embodiments provides a composition for topical delivery comprising ibuprofen and/or an ibuprofen salt, a nitric oxide donor, and optionally, a hostile biophysical environment. In some cases, the composition may be stabilized using a stabilization polymer such as xanthan gum, KELTROL® BT and/or KELTROL® RD; propylene glycol; and a polysorbate surfactant such as Polysorbate 20, which unexpectedly provides temperature stability to the composition, e.g., at elevated temperatures such as at least 40° C. (at least about 104° F.), as compared to compositions lacking one or more of these.

Abstract: A composition for promoting hair growth in humans can include at least three of the following ingredients: Pygeum Africanum, Serenoa Repens, Ganoderma Lucidum, Piper Methysticum, and Zinc. The amount by weight of the identified ingredients in a particular formulation may range from at least 5% to no more than 50% of the formulation.

Abstract: The invention relates to a method of treating and preventing ageing of the pilosebaceous unit and/or alopecia in human through the administration of taurine and/or hypotaurine and/or the acceptable salts thereof in an oral composition. Specifically, the invention relates to a method of treating and preventing miniaturization of the hair follicle. The invention also relates to the use of polyphenols to achieve these same ends. Finally, the invention relates to oral compositions that include polyphenols or taurine and/or hypotaurine and/or the acceptable salts thereof as active ingredients.

Abstract: Provided herein are compounds and methods for the treatment of brain cancer in a mammal, wherein the method comprises the administration to the mammal a compound that stabilizes tubulin dimers or microtubles at G2-M interface during mitosis but is not a substrate for MDR protein. In particular, the present application relates to the use of an orally effective abeo-taxane, alone or in combination with temozolomide or bevacizumab, for the treatment of brain cancer.

Abstract: The invention relates to a film-shaped administration form for surface administration of at least one active ingredient and/or foodstuff to a living thing. Said administration form comprises at least one layer containing an active ingredient and/or foodstuff, said layer being based on cross-linked hydrophilic polymers and containing 20 wt.-% glycerine as a softener, in relation to the total amount of cross-linked hydrophilic polymers.

Abstract: Disclosed is an ophthalmic composition which is characterized by containing (A) a vitamin A, (B) a polyoxyethylene polyoxypropylene glycol, and (C) an oil component that is selected from the group consisting of castor oil, soybean oil, sesame oil, peanut oil, olive oil, almond oil, wheat germ oil, corn oil, rapeseed oil, sunflower oil, purified lanolin and gel hydrocarbon.

Abstract: A composition for cosmetics is provided, which has a UV shielding effect and which can produce a cosmetic having good dispersibility, an excellent UV shielding effect and excellent use feeling, cosmetic effect, long-lasting cosmetic performance. The cosmetic obtained by using the same is provided. The composition for cosmetics includes (A) microparticulate titanium dioxide, (B) one kind or two or more kinds of magnesium hydroxide and calcium hydroxide. The composition for cosmetics preferably contains further (C) a clay mineral. The compounding weight ratio among (A): (B): (C) is preferably 20 to 60: 3 to 40: 0 to 77. In addition, the composition for cosmetics is preferably one in which a mixed powder of (A), (B) and (C) is lipophilically treated.

Abstract: A capsular design is disclosed for self-administered delivery of a pre-determined amount of liquid medication. The capsular design can be constructed as having either a single piece or two piece capsular wall construction where a portion of the liquid medication contained within can be administered sublingually and the remaining portion can be subsequently swallowed for gastro-intestinal absorption.

Abstract: Described herein are methods of inhibiting angiogenesis, and treating and preventing disorders associated with angiogenesis by administering anti-angiogenesis compounds to a subject.

Abstract: The present invention relates to magnetic nanostructures as theranostic agents, which provide dual function as diagnostic and therapeutic agents. In particular, the present invention relates to compositions comprising magnetic nanostructures and their use as targeted therapeutic agents for cancers (e.g., medulloblastoma) and Alzheimer's disease and related diseases and conditions.

Abstract: There are provided, inter alia, photolabile compounds and methods useful for the formation of dimers of biological molecules and subsequent dissociation of the dimers.

Abstract: Skin care composition comprising a plurality of interference pigments and a dermatologically acceptable carrier. The plurality comprises at least a first interference pigment which reflects a first color, and at least a second interference pigment which reflects a second, complementary color. The total amount of interference pigments is from about 0.1% to about 10%.

Abstract: The present invention provides water-in-oil type emulsion sunscreen cosmetics that achieve an excellent UV blocking effect, and have excellent effects in the prevention and inhibition of discoloration (discoloration to red). The water-in-oil emulsion sunscreen cosmetic according to the present invention is characterized by comprising: (a) octocrylene; (b) hydrophobized zinc oxide; (c) cationic surfactant; and (d) silica.

Abstract: This invention relates to methods and compositions for degrading collagen in mammalian skin, thereby improving the appearance and/or reducing the size of a closed wound, which may be a scar or a keloid and cellulite or other conditions wherein excessive collagen is a problem.

Abstract: Bone graft materials include a bone-grafting material, which encourages regeneration of a missing bone tissue while being absorbed by the missing bone tissue, and a coating material, which is composed of at least one selected from the group consisting of magnesium, calcium hydroxyapatite, and mixtures thereof.

Abstract: The invention relates to the use of esters of 2-ethylbutanol with C4-36 dicarboxylic acids or C4-36 dicarboxylic acids in cosmetics and/or pharmaceutical preparations. The compounds are characterized by a particularly light feeling.

Abstract: The invention provides a cosmetic composition for reducing facial perspiration. The facial antiperspiration balm is a homogeneous mixture of a cosmetic gel and a cosmetic cream. The balm has a lowered amount of the active agent, moisturizes and protects the skin, and provides a pleasant feeling.

Abstract: A water-based and surfactant-free microwave synthesis of polymer nanoparticles includes the entrapment of diisopropyl fluorophosphatase (DFPase) within poly(4-vinylpyridine) (PVP) nanoparticles. The resulting nanoparticles are approximately 80-100 nm in diameter and reactive activity of DFPase is maintained after encapsulation.

Abstract: Subject of the invention is a method for the production of a carnitine granulate, which includes the steps of (a) providing an aqueous solution comprising at least 65% (w/w) carnitine, (b) providing a particulate carrier comprising silica, the carrier having an average particle size of more than 150 ?m, and (c) mixing the aqueous solution and the carrier. Another subject of the invention is a carnitine granulate.

Abstract: Disclosed are methods of enhancing growth of corn plants, comprising treating corn seed or the corn plant that germinates from the seed with an effective amount of at least one chitooligosaccharide, wherein upon harvesting the corn plant exhibits at least one of increased plant yield measured in terms of bushels/acre, increased root number, increased root length, increased root mass, increased root volume and increased leaf area, compared to untreated corn plants or corn plants harvested from untreated corn seed.