Patents Examined by Hasan S. Ahmed
  • Adjuvant nanoemulsions with phospholipids
    Patent number: 10357568
    Abstract: To formulate amphiphilic pharmacological agents (in particular, amphiphilic immunopotentiators) in oil-in-water emulsions the invention provides an oil-in-water emulsion comprising an aqueous phase, an oil phase, a surfactant, and a phospholipid.
    Type: Grant
    Filed: March 23, 2012
    Date of Patent: July 23, 2019
    Assignee: GLAXOSMITHKLINE BIOLOGICALS S.A.
    Inventors: Luis Brito, Manmohan Singh, Derek O'Hagan
  • Membrane-forming composition, soft and hard capsules prepared based on this composition and the preparation methods
    Patent number: 10350568
    Abstract: A membrane-forming composition, soft and hard capsules prepared based on the composition and the preparation methods are described. The membrane-forming composition includes pullulan polysaccharide, gellan gum, amino acid moisturizing agent, anti-hygroscopic agent and so on. It is suitable for the fabrication of hard or soft capsules. The membrane-forming composition can gelate without alkali metal ions. It has a high moisture retention rate which makes it not easy to take up moisture and turn soft in high humid environment, and it will not turn yellow during long time storage. Furthermore, the membrane-forming composition is made up of pure natural materials.
    Type: Grant
    Filed: August 2, 2016
    Date of Patent: July 16, 2019
    Assignee: JIANGSU LEFAN CAPSULE CO., LTD.
    Inventors: Peiyong Liu, Peng Lei, Li Wang, Xiao Dou, Xudong Zhu, Yichi Zhang
  • Combination of an oxidant, a photosensitizer and a wound healing agent for oral disinfection and treatment of oral disease
    Patent number: 10322179
    Abstract: The present document describes methods of use of photo activated compositions for oral disinfection and/or treatments which comprise at least one oxidant, at least one photoactivator capable of activating the oxidant, and at least one healing factor chosen from hyaluronic acid, glucosamine and allantoin, in association with a pharmacologically acceptable carrier.
    Type: Grant
    Filed: February 15, 2017
    Date of Patent: June 18, 2019
    Assignee: KLOX TECHNOLOGIES INC.
    Inventors: Remigio Piergallini, Nikolaos Loupis
  • Clear wet sprays and gels
    Patent number: 10314774
    Abstract: Sun-care products are described that protect from UV radiation and do not turn white when applied to wet skin. The sun-care product may comprise (A) a cosmetically-acceptable, substantially non-aqueous vehicle, and (B) a UV active, wherein said non-aqueous vehicle comprises alcohol in an amount of 50% (w/w) or less based on the weight of the sun-care product and an ester wherein said non-aqueous vehicle comprises at least 10%>by weight esters based on the total weight of the non-aqueous vehicle and said sun-care product is substantially non-whitening upon application to wet skin.
    Type: Grant
    Filed: April 27, 2012
    Date of Patent: June 11, 2019
    Assignee: ISP Investment LLC
    Inventors: Hani M. Fares, Donald I. Prettypaul, Diane M. Kennedy
  • Coating formulations for scoring or cutting balloon catheters
    Patent number: 10314947
    Abstract: The present invention is related to scoring or cutting balloon catheters carrying at least on a portion of their surface at least one drug or drug preparation and at least one lipophilic antioxidant at a ratio of 3-100% by weight of the at least one lipophilic antioxidant in relation to 100% by weight of the drug, wherein a combination of the at least one drug being a limus drug and the at least one lipophilic antioxidant being butylated hydroxytoluene is excluded.
    Type: Grant
    Filed: July 31, 2017
    Date of Patent: June 11, 2019
    Assignee: Angioscore, Inc.
    Inventors: Ulrich Speck, Madeleine Caroline Berg
  • Methods of treating non-alcoholic steatohepatitis (NASH) using cysteamine products
    Patent number: 10307386
    Abstract: The disclosure relates, in general, to treatment of fatty liver disorders comprising administering compositions comprising cysteamine products. The disclosure provides administration of enterically coated cysteamine compositions to treat fatty liver disorders, such as non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH).
    Type: Grant
    Filed: November 28, 2016
    Date of Patent: June 4, 2019
    Assignee: The Regents of the University of California
    Inventors: Ranjan Dohil, Jerry Schneider
  • Transdermal therapeutic system comprising active ingredient particles and having increased active ingredient flux
    Patent number: 10292942
    Abstract: The invention relates to a transdermal therapeutic system, preferably a transdermal patch, having an active ingredient-containing matrix formed substantially of a water-insoluble base material, such as rubber and synthetic polymers, into which is incorporated water-soluble and/or water-swellable inclusion bodies, e.g. inclusion bodies formed from polyvinyl alcohol or polyethylene glycol, that further include micronized or nanoscale active ingredient particles.
    Type: Grant
    Filed: May 30, 2007
    Date of Patent: May 21, 2019
    Assignee: LTS Lohmann Therapie-Systeme AG
    Inventors: Michael Horstmann, Mohammad Sameti, Tobias Jung
  • Stable layer-by-layer coated particles
    Patent number: 10278927
    Abstract: Systems and methods for coating a particle core with a layer-by-layer film are disclosed.
    Type: Grant
    Filed: April 23, 2013
    Date of Patent: May 7, 2019
    Assignee: Massachusetts Institute of Technology
    Inventors: Paula T. Hammond, Zhiyong Poon
  • Hair strengthening conditioner formulation with reduced cost, easy formulation and improved performance
    Patent number: 10258553
    Abstract: A hair strengthening conditioner formulation for application to human or animal hair for the purpose of strengthening and improving the hair. The present invention is for external application but may also be used in combination with dietary supplement compositions. The present hair strengthening conditioner comprises a proprietary mixture of a number of compounds as described in the tables and the claims.
    Type: Grant
    Filed: September 17, 2018
    Date of Patent: April 16, 2019
    Assignee: SERENDIPITY TECHNOLOGIES LLC.
    Inventor: Amen Dhyllon
  • Oral pharmaceutical formulation of BCS class III molecules
    Patent number: 10258692
    Abstract: The present invention concerns an oral pharmaceutical formulation made from a microemulsion between an aqueous solution comprising at least one BCS (Biopharmaceutics Classification System) class III active principle and one oily phase comprising an oily vehicle that is self-emulsifiable on contact with water.
    Type: Grant
    Filed: June 14, 2013
    Date of Patent: April 16, 2019
    Assignee: ETHYPHARM
    Inventors: Caroline Ailhas, Catherine Herry
  • Peritoneal dialysis solution
    Patent number: 10251953
    Abstract: The present invention relates to a solution for peritoneal dialysis consisting of one or more separate solutions. A treatment free of side-effects with a simultaneous lowering of blood pressure can be achieved in that the solution contains sodium ions in a concentration in the region from 121 to 129 mmol/l, preferably at 125 mmol/l. The invention furthermore relates to a double-chambered pouch having a peritoneal dialysis solution consisting of two separate solutions which consists of a plastic pouch in which a first chamber with the first separate solution and a second chamber with the second separate solution are arranged adjacent to one another, with both chambers being separated from one another by a weld seam dimensioned such that it opens on pressure onto one of the chambers filled with liquid so that the content of the two chambers can be mixed with one another.
    Type: Grant
    Filed: May 12, 2005
    Date of Patent: April 9, 2019
    Assignee: Fresenius Medical Deutschland GMBH
    Inventors: Jutta Passlick-Deetjen, Thomas P. Schaub, Georg Topp
  • ACC inhibitors and uses thereof
    Patent number: 10208044
    Abstract: The present invention provides for compounds of formula I as acetyl-CoA carboxylase (ACC) inhibitors. The ACC inhibitors are useful for the prevention or treatment of metabolic syndrome, including obesity, dyslipidemia and hyperlipidemia in humans. The inhibitor compounds are also capable of inhibiting the ACC enzyme found in plants, parasites and bacteria.
    Type: Grant
    Filed: May 8, 2014
    Date of Patent: February 19, 2019
    Assignee: GILEAD APOLLO, LLC
    Inventors: Jeremy Robert Greenwood, Geraldine C. Harriman, George Borg, Craig E. Masse
  • ACC inhibitors and uses thereof
    Patent number: 10208063
    Abstract: The present invention provides compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same. Specifically, bicyclic heteroaryl derivatives containing a imidazole, thiazole or oxazole fused to a pyridinone, pyrimidinone or pyrimidindione are provided. These compounds have therapeutic utility toward treating an ACC enzyme mediated disorder such as obesity in a subject, upon administration in an effective amount to said subject.
    Type: Grant
    Filed: May 8, 2014
    Date of Patent: February 19, 2019
    Assignee: GILEAD APOLLO, LLC
    Inventors: Jeremy Robert Greenwood, Geraldine C. Harriman, George Borg, Craig E. Masse
  • Methods and compositions for treating rosacea
    Patent number: 10149985
    Abstract: There is provided a method for treating rosacea comprising a composition which comprises at least one oxidant, at least one photoactivator capable of activating the oxidant, and at least one healing factor chosen from hyaluronic acid, glucosamine and allantoin, in association with a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: May 24, 2016
    Date of Patent: December 11, 2018
    Assignee: KLOX TECHNOLOGIES INC.
    Inventors: Remigio Piergallini, Nikolaos Loupis, Francesco Bellini
  • Malic acid stabilized nanoceria particles
    Patent number: 10143661
    Abstract: A process for making nanoparticles of biocompatible materials is described, wherein an aqueous reaction mixture comprising cerous ion, malic acid, an oxidant, and water, is provided along with temperature conditions to directly form within the reaction mixture, a stable dispersion of nanoceria particles. Biocompatible nanoparticles comprised of ceria and malic acid are described. A reduction in cell death in a murine model of ischemic stroke utilizing intact brain slices is demonstrated by a prophylactic treatment of ceria nanoparticles prepared with malic acid.
    Type: Grant
    Filed: October 17, 2014
    Date of Patent: December 4, 2018
    Assignee: Cerion, LLC
    Inventor: David Wallace Sandford
  • Gradient copolymer, composition including same and cosmetic make-up or care method
    Patent number: 10117824
    Abstract: Novel gradient copolymers including at least two different and specifically selected monomers, and cosmetic or skin-care compositions including same. The invention also relates to a cosmetic method for make-up or the care of keratin materials, in particular the skin of the body or of the face, the nails, the hair and/or the eyelashes, comprising the application of a cosmetic composition as defined above on said materials.
    Type: Grant
    Filed: April 17, 2014
    Date of Patent: November 6, 2018
    Assignee: L'OREAL
    Inventor: Celine Farcet
  • Malononitrile compounds for controlling animal pests
    Patent number: 10117430
    Abstract: The invention relates to the use of a compound of formula (I) or a salt thereof for combating animal pests, where the symbols and indices are defined in the specification.
    Type: Grant
    Filed: December 6, 2013
    Date of Patent: November 6, 2018
    Assignee: BASF SE
    Inventors: Ralph Paulini, Matthias Pohlman, Sebastian Soergel, Henricus Maria Martinus Bastiaans, Sarah Thompson, Cecille Ebuenga Doyog, Anna Malveda Umali, Rhoel Suiza Cosare
  • Wound dressings, methods and apparatus for making same and storage and use thereof
    Patent number: 10111979
    Abstract: Provided is a wound dressing prepared from whole blood that is clotted ex vivo to form a sheet of clotted blood that is applied onto the skin over a sight of skin injury.
    Type: Grant
    Filed: November 5, 2015
    Date of Patent: October 30, 2018
    Assignee: RedDress Ltd.
    Inventors: Alon Kushnir, Igal Kushnir
  • Reduction of opioid blood fluctuations
    Patent number: 10111869
    Abstract: The present invention relates to the use of a sustained release matrix containing at least one opioid for producing a solid oral formulation in table form suitable for reducing blood concentration fluctuations of said opioid.
    Type: Grant
    Filed: April 11, 2014
    Date of Patent: October 30, 2018
    Assignee: ETHYPHARM
    Inventors: Catherine Herry, Maryline Boyer, Francoise Vauzelle-Kervroedan, Pascal Oury
  • Allergen dosage form
    Patent number: 10080719
    Abstract: The invention provides allergen containing pharmaceutical products and in particular fast-dispersing solid allergen dosage forms. In particular, fast-dispersing, non-compressed solid dosage forms suitable for oromucosal administration comprising a matrix and at least one allergen are provided. Suitable matrices are gelatine, starch and mannitol. Methods for the dosage forms are also provided.
    Type: Grant
    Filed: July 6, 2016
    Date of Patent: September 25, 2018
    Assignee: ALK-ABELLÓ A/S
    Inventors: Henrik Hugo Jacobi, Annette Roemmelmayer Lundegaard, Christian Gauguin Houghton, Stig Aasmul-Olsen, Lise Lund Maerkedahl, Jan Sondergaard Andersen