Abstract: A monitoring device may include a housing with: a first connector that mechanically couples to a baby bottle; and a second connector that mechanically couples to a nipple; a tube having a first opening defined by a first edge proximate to the first connector and a having second opening defined by a second edge proximate to the second connector. Moreover, the housing may include a set of sensors that perform measurements associated with feeding. During operation, the monitoring device may perform the measurements while a baby is performing the feeding, where the measurements are associated with sucking, swallowing and breathing by the baby. Then, the monitoring device may dynamically provide feedback based at least in part on the measurements. For example, the feedback may include: change to the feeding (such as when to dynamically pause the feeding), a change to a size of the nipple or the baby bottle, etc.

Abstract: Z maps combined with a standardized stimulus in the form of a targeted arterial partial pressures of carbon dioxide provide surprisingly enhanced images for the assessment of pathological CVR. For example, the z-map assessment of patients with known steno-occlusive diseases of the cervico-cerebral vasculature showed an enhanced resolution of the presence, localization, and severity of the pathological CVR. Z-map have been found to be useful to reduce the confounding effects of test-to-test, subject-to-subject, and platform-to-platform variability for comparison of CVR images showing the importance of combining this analysis with the standardized stimulus.

Abstract: An adaptive processing of the pulsatility signal can improve the pulse wave analysis (PWA) leading to a better blood pressure estimation. The technique is based on transforming the pulsatility signal so that the fiducial points required for the PWA are well-defined.

Abstract: A method, apparatus and computer program product, the method comprising: obtaining electrical information from a plurality of electrodes disposed on a distal end assembly of a catheter within a heart of a patient as the catheter is being maneuvered within the heart; dynamically identifying a portion of the distal end assembly that is displaced from tissue wall of the heart, based upon the electrical information received from the plurality of electrodes; generating a visual representation of the distal end assembly; dynamically distorting the visual representation by warping (the identified portion of the distal end assembly; and rendering the visual representation as dynamically distorted to the display device.

Abstract: Various methods and systems for color flow ultrasound imaging of arteries and veins are provided. In one embodiment, a method comprises acquiring a color flow image, automatically identifying an artery and a vein within the color flow image, and adjusting at least one imaging parameter responsive to the automatic identification of the artery and the vein. In this way, flow velocities and volume flow in arteries and veins may be measured with minimal adjustments or input by a user, thereby increasing the accuracy and consistency of measurements and reducing the time needed for blood flow measurements.

Abstract: A real-time human posture tracking and calibration device and a system for tumor radiotherapy are provided, which may replace the traditional treatment bed of a linear accelerator. For tumor targets in areas such as the head and neck that do not move with respiration, the system tracks changes in the skin external contour and the static position of the tumor. For tumors in the chest and abdomen that are significantly affected by respiration, the system first tracks changes in the skin external contour and then compensates for the displacement of the tumor target moving with respiration.

Abstract: A system and method for performing photoacoustic tomography is provided. Encoded light modulated using one or more digital encoding sequences is emitted using a plurality of light sources. Ultrasonic signals emitted by target biological tissues that absorbed at least a portion of the emitted encoded light are received using a plurality of receivers. The received ultrasonic signals are correlated using one or more reference signals encoded using the one or more digital encoding sequences to determine timing associated with the received ultrasonic signals. Locations associated with the target biological tissues are determined based on the determined timing.

Abstract: The present disclosure provides medical devices having MRI-compatible circuitry. Preferably, the devices do not project an enlarged profile, yet their position can be determined during an iMRI procedure. Illustrative embodiments of such a device can include a base surface, a first conducting layer disposed on the base surface, a first insulating layer disposed over at least a portion of the first conducting layer, and a second conducting layer disposed over at least a portion of the first insulating layer.

Abstract: There is provided an apparatus (100) for determining a blood pressure measurement for a subject (102). The apparatus (100) comprises a processor (104) configured to acquire, from a light sensor (106), measurements of an intensity of light (108) of a first wavelength range reflected from the skin (110) of the subject (102) for a range of forces at which the light sensor (106) is applied to the skin. The processor (104) is further configured to determine a pulse amplitude from the measurements of light intensity at the range of applied forces and analyze the determined pulse amplitudes to determine a systolic blood pressure measurement based on the applied force at which the pulse amplitude drops below a predefined threshold and/or an integral of the pulse amplitudes and/or a diastolic blood pressure measurement based on the applied force at which an initial rise in the pulse amplitude is identified.

Abstract: Electromagnetic sensing for use with ablation treatment devices are described. Generally, an elongate body may be configured for introduction into an esophageal lumen and a distal portion may be pivotably coupled to the elongate body such that actuation of the distal portion reconfigures the distal portion within a plane relative to the elongate body. The elongate body may define one or more openings along the distal portion and which are in fluid communication with a fluid port. A sensor may also be positioned near or at a distal end of the distal portion where the sensor is configured to communicate with an electromagnetic navigational system to determine a distance to an ablation catheter.

Abstract: Described herein are systems, devices, and methods for non-invasive pregnancy testing. The systems, devices, and methods can be used to provide pregnancy status information of a subject by detecting cardiovascular activity of a fetus in the subject. Subjects can include ruminants, ungulates, and humans.

Abstract: Systems and methods of reconstructing photoacoustic imaging data corresponding to a brain of a subject through a skull of a subject utilizing a reconstruction method that incorporates a spatial model of one or more acoustic properties of the brain and skull of the subject derived from an adjunct imaging dataset.

Abstract: A finger insert for use with a nailfold imaging device includes a housing to receive the user's finger and an immersion substance (e.g., immersion oil), and a deformable pad that holds the user's finger in place during imaging, as well as prevent bubble formation in the substance. The housing includes a transparent wall to facilitate imaging of the finger. The transparent wall includes multiple angled portions that prevent or reduce contact between the nailfold and the wall, to ensure sufficient blood flow through the nailfold region for imaging.

Abstract: Self-locating active markers (SLAMs) can locate themselves with respect to patient's internal anatomy and be physically located and visible in an operating room (OR) coordinate space, which can increase precision of co-registration between augmented reality (AR) systems and medical imaging. Each SLAM may include 9-axis accelerometers and ultrasound technology to locate themselves by orientation and distance to internal skeletal and/or soft tissue anatomy. Multiple SLAMS affixed to skin near operative site at a location visible to a surgical navigation system and/or the surgeon's AR Headset during a procedure may report relative distance changes between their location and internal skeletal anatomy in order to maintain surgical navigation system or AR coordinate system co-registration to the imaged internal coordinate systems. Sequential time of flight calculations from ultrasound array alone or in combination with 9-axis accelerometer data may be used.

Abstract: The present disclosure provides a body-insertion device for a body, which comprises a first moving unit for moving an image acquisition unit; an insertion unit; and a second moving unit for moving the insertion unit. The first moving unit comprises at least one of a 1-1 module for moving the image acquisition unit in a 1-1 direction, a 1-2 module for moving the image acquisition unit in a 1-2 direction, and a 1-3 module for moving the image acquisition unit in a 1-3 direction. The second moving unit comprises at least one of a 2-1 module for moving the insertion unit in a 2-1 direction, a 2-2 module for moving the insertion unit in a 2-2 direction, and a 2-3 module for moving the insertion unit in a 2-3 direction.

Abstract: According to one aspect of the invention, a method for assessing physiological properties of a biological tissue is provided. The method comprising the steps of transmitting from a first coaxial probe, receiving at a second coaxial probe and assessing physiological properties. The transmission from the first probe is a microwave signal. The second coaxial probe receives a microwave signal. The first coaxial probe and the second coaxial probe are arranged in connection with the biological tissue. The physiological properties of the biological tissue between the coaxial probes are assessed based on the microwave signal transmitted and received across the biological tissue. The invention further relates to a system and a coaxial probe useful in performing such a method.

Abstract: Example embodiments describe a computer implemented method for obtaining parameterized characteristics of a tissue comprising obtaining at least two weighted MRI volume scans of the tissue, and transforming the two weighted MRI volume scans into parameters of a parameterized voxel-based model of the tissue by combined performing, by a super-resolution imaging technique, constructing a volume comprising voxels of the parameterized voxel-based model, and, by a quantitative MRI modelling technique, constructing the parameters for the respective voxels of the parameterized voxel-based model.

Abstract: Systems, catheter and methods for treating Atrial Fibrillation (AF) are provided, which are configure to illuminate a heart tissue having a lesion site; obtain a mitochondrial nicotinamide adenine dinucleotide hydrogen (NADH) fluorescence intensity from the illuminated heart tissue along a first line across the lesion site; create a 2-dimensional (2D) map of the depth of the lesion site along the first line based on the NADH fluorescence intensity; and determine a depth of the lesion site at a selected point along the first line from the 2D map, wherein a lower NADH fluorescence intensity corresponds to a greater depth in the lesion site and a higher NADH fluorescence intensity corresponds to an unablated tissue. The process may be repeated to create a 3 dimensional map of the depth of the lesion.

Abstract: A system is configured to diagnose sleep comprising an apparatus configured to be attached to a patient; the apparatus comprises: i) an optical sensor configured to measure a blood volume pulse of the patient; and ii) a wireless communication interface configured to wirelessly transmit the measured blood volume pulse. The system further comprises means for performing: i) obtaining the wirelessly transmitted measured blood volume pulse; and ii) deriving from the blood volume pulse the peripheral arterial tone; iii) determining occurrences of sleep events from changes in the peripheral arterial tone.

Abstract: The present invention relates to an apparatus for sample taking from a fluid-conducting system, wherein the apparatus has at least one adapter which comprises at least one septum and at least one cannula displaceable relative to the septum, wherein the cannula is displaceable such that it penetrates the septum in a sample taking position and does not penetrate the septum in a flushing position; and wherein the adapter has at least one flushing region for a flushing medium which is arranged such that it is in fluid communication with the inner space of the cannula in the flushing position of the cannula; and wherein the apparatus has at least one receiving region having locking means for the fluid-conducting system by which the fluid-conducting system is fixable in a defined position relative to the adapter. The present invention furthermore relates to a blood treatment device and to a method for taking a sample from a fluid-conducting system.