Abstract: Example embodiments presented herein relate to solutions for analyzing and/or classifying microwave scattering data. The analyzing and/or classifying may be utilized for estimating an internal condition in an enclosed volume.

Abstract: A computer assisted surgical system that includes an apparatus (110) for imaging a region of interest of a portion of an anatomy of a subject; a memory containing executable instructions; and a processor programmed using the instructions to receive two or more two-dimensional images of the region of interest taken at different angles from the apparatus and process the two or more two-dimensional images to produce three dimensional information associated with the region of interest.

Abstract: A magnetic resonance imaging apparatus includes an acquisition unit which acquires first data in which a tissue of interest has higher signal intensity than a background and second data in which the tissue of interest has lower signal intensity than the background, with regard to images of the same region of the same subject, and a generation unit which generates, on the basis of the first data and the second data, third data in which the contrast of the tissue of interest to the background is higher than those in the first and second data.

Abstract: A computer assisted surgical system that includes an apparatus for imaging a region of interest of a portion of an anatomy of a subject; a memory containing executable instructions; and a processor programmed using the instructions to receive two or more two-dimensional images of the region of interest taken at different angles from the apparatus and process the two or more two-dimensional images to produce three dimensional information associated with the region of interest.

Abstract: The present invention is directed to a system and method for performing tissue, preferably bone tissue manipulation. The system and method may include implanting markers on opposite sides of a bone, fractured bone or tissue to facilitate bone or tissue manipulation, preferably in-situ closed fracture reduction. The markers are preferably configured to be detected by one or more devices, such as, for example, a detection device so that the detection device can determine the relative relationship of the markers. The markers may also be capable of transmitting and receiving signals. An image may be captured of the bone or tissue and the attached markers. From the captured image, the orientation of each marker relative to the bone fragment may be determined. Next, the captured image may be manipulated in a virtual or simulated environment until a desired restored orientation has been achieved. The orientation of the markers in the desired restored orientation may then be determined.

Abstract: A method and system for autoregressive model based pigtail catheter motion prediction in a fluoroscopic image sequence is disclosed. Parameters of an autoregressive model are estimated based on observed pigtail catheter tip positions in a plurality of previous frames of a fluoroscopic image sequence. A pigtail catheter tip position in a current frame of the fluoroscopic image sequence is predicted using the fitted autoregressive model. The predicted pigtail catheter tip position can be used to constrain pigtail catheter tip detection in the current frame. The predicted pigtail catheter tip position may also be used to predict abnormal motion in the fluoroscopic image sequence.

Abstract: Re-calibration of pre-recorded images during interventions uses an interventional system including an imaging device providing images of an object, a needle device, and a processing device. The needle device includes a sensor for providing data corresponding to tissue properties. The processing device is configured to perform an overlay registration of pre-recorded images and live images provided by the imaging device, utilizing the data from the sensor. Thus, the accuracy of an overlay of images is increased.

Abstract: An ultrasound diagnostic device includes: an ultrasound probe which transmits ultrasound toward a tested subject by a plurality of transducers and obtains a received signal; a beam forming section for adding the received signal for each of the transducers with matching a phase of the received signal; an image processing section which generates an image data; a coherent factor calculation section which calculates a coherent factor which represents a ratio of a coherent sum to an incoherent sum; a coherent factor correction section which corrects the coherent factor so as not to be smaller than a predetermined value; and a signal correction section which correct the received signal after having been subject to the adding, by multiplying the received signal after having been subject to the adding by the coherent factor corrected by the coherent factor correction section as a coefficient.

Abstract: A tissue manipulation system includes Programmable Markers configured to be implanted on opposite sides of one or more portions of tissue within a patient's body, Markers communicating with one another to enable a determination of their relative positions and External Device receiving and transmitting signals to Markers containing information as to Marker's positions. Device is configured to: capture an image of the tissue portions with Markers; manipulate the image of the tissue portions in a virtual environment or a simulated environment to a desired restored orientation; determine desired positions Markers will have when the tissue portions are in the desired restored orientation; program implanted Markers with the desired orientations.

Abstract: Multimodal optical and magnetic resonance imaging methods based on the use of persistent luminescence nanoparticles. Use of mesoporous persistent luminescence <<core-shell>> complexes for theranostic applications.

Abstract: A testing apparatus for an optoacoustic device includes a light pulse sensor operatively connected to a light output port of the optoacoustic device, the light pulse sensor being adapted to sense a pulse of light capable of generating an optoacoustic response in a subject and to distinguish between the light pulse and the at least one other light pulse on the basis of the predominant wavelength. The light pulse sensor outputs a trigger signal associated with the distinguished light pulse when such light pulse is sensed. A transducer signal simulator outputs a first plurality of electrical signals simulating those produced by a transducer array and reflective of an optoacoustic response in a subject to a light pulse at a first wavelength in response to a trigger signal from the light pulse sensor associated with a light pulse having a first wavelength.

Abstract: Methods and systems for 4D electromagnetic tomographic differential (dynamic) fused imaging and mapping of electrical excitation of biological tissues. A plurality of electromagnetic field sources and detectors generate and detect an electromagnetic field domain in a target area. A biological tissue is positioned within the target area, and an electromagnetic field domain is generated via a selected plurality of sources. The field generated by each source is selectively characterized so that each of a selected plurality of detectors recognizes a source of field from the plurality of sources. The sources and detectors are controlled so that fields generated by the selected sources are received by the selected detectors after interacting with the tissue. Based on the field received at each detector, a complex interference (scattering) matrix is derived from the tissue-generated field, and anatomical and functional image information are reconstructed from this matrix.

Abstract: An apparatus is disclosed for thermal therapy in a male prostate patient. The apparatus includes, in preferred embodiments, a long tubular element that is to be inserted into a patient's urethra so that a first tip end of it reaches up into the patient's diseased prostate. The elongated portion includes a narrow cylindrical tube within which an ultrasonic array is disposed along the long axis of the cylinder. Fluid is pumped into and out of a treatment zone of said patient as needed to control a temperature of a region in said treatment zone. A motorized driver is used to controllably rotate said elongated portion and the ultrasound array therein about the long axis of the apparatus so as to deliver acoustic energy to said diseased tissue. Various control and monitoring components may be used in conjunction with the present apparatus to design, control, and terminate the therapy.

Abstract: A prone CT breast x-ray imaging system is described that can image a full breast to create a conventional two-dimensional digital image in very high resolution (e.g., ?25 micron pixels). The system is capable of imaging the entire breast in three-dimensional based on multiple projection views from a one-dimensional or two-dimensional detector. Data can be acquired and reconstructed with a limited number of views from limited angles or with conventional cone beam CT algorithms. The resulting three-dimensional image enables the detection and diagnosis of fine micro calcifications and small masses as may be distributed throughout the breast, thus allowing radiologists to make an improved determination of malignancy as opposed to conventional two-dimensional digital mammography. In addition, the injection of intravenous contrast in conjunction with or without pre and post contrast subtraction imaging provides a radiologist with morphologic information on the existing tumor burden in the breast.

Abstract: Systems, apparatus and methods are provided through which an injector system automates a process of injecting an individual dose from a multiple dose of a radiotracer material. In some embodiments, the injector system includes a first dose calibrator system that receives a multidose vial of a radiotracer, a second dose calibrator system, an injection pump and an intravenous needle. In some embodiments, the first dose calibrator system and the multidose vial have an integrated shape. In some embodiments, the first dose calibrator system includes a pneumatic arm that receives the multidose vial.

Abstract: A method and apparatus for mapping a location of a point within the body is disclosed. A plurality of positional reference nodes are determined, each aligned on a first element. A second element is mapped with reference to the plurality of reference nodes to determine the relative location of a point on the second element.

Abstract: A fluorescence diagnosis system has a viewing system at least one light source and a camera system. The at least one light source can be operated in three modes, a first generating white light, a second with a first fluorescence excitation light of a first excitation wavelength and a third in which a second fluorescence excitation light of a second excitation wavelength is generated producing a fluorescence image in the NIR range. The camera system is sensitive at least in the visible and the NIR range. The system further comprises an image processing system for converting the fluorescence image in the NIR range into a visible image.

Abstract: A magnetic resonance imaging apparatus includes an acquisition unit which acquires first data in which a tissue of interest has higher signal intensity than a background and second data in which the tissue of interest has lower signal intensity than the background, with regard to images of the same region of the same subject, and a generation unit which generates, on the basis of the first data and the second data, third data in which the contrast of the tissue of interest to the background is higher than those in the first and second data.

Abstract: An ultrasonic diagnostic apparatus comprises a driving unit, a nonlinear component extracting unit, a first image data generating unit, a second image data generating unit and a control unit. The driving unit drives an ultrasonic transducer to transmit an ultrasonic wave to a subject. The nonlinear component extracting unit extracts a nonlinear component corresponding to the ultrasonic wave from a reception signal received by the ultrasonic transducer. The first image data generating unit generates a first image data based on the nonlinear component. The second image data generating unit generates a second image data based on the reception signal. The control unit arbitrarily distributes a sound output for transmission in a definite period of time to a first ultrasonic transmission for generating the first image data and a second ultrasonic transmission for generating the second image data.

Abstract: The invention relates to a medical unit comprises a 3D radar array for the detection of positional or movement data of objects in an examination space and a processing unit for the evaluation of the detected data, with the processing unit being connected to the medical unit and to the 3D radar array, and with the evaluated data being used to control the medical unit or for post-processing data acquired by the medical diagnostic or therapeutic unit. The invention also relates to a method for improving examination or treatment workflows with the medical unit, comprising: detecting positional or movement data of objects in the examination space by the 3D radar array; generating control commands for the medical unit based on the detected data; and post-processing image or spectroscopy data received by the medical based on the detected data. The medical unit is a medical diagnostic or therapeutic unit.