Abstract: This disclosure describes techniques and devices for improvement of surgical outcomes for tissue removal surgeries. A surgical instrument with adjustable and selective resection is described. The disclosed devices and methods allow selective tissue removal.

Abstract: A securement device for retaining medical tubing, catheters, and other medical fixtures proximal a patient's skin. The device has a base, at least one channel formed in the base, a flexible strap for overlying the base, and a coupling assembly for coupling the strap to the base. Embodiments for use with Foley catheters include a plurality of channels of differing diameters. Embodiments for use with a peripheral catheter include a single channel for retaining a spin nut. The coupling assembly includes left and right tracks in left and right sides of the base, and left and right rails on an underside of the flexible strap at left and right ends of a body of the strap. The left rail is removably coupled and held within the left track on the base, and the right rail is removably coupled and held within the right track on the base.

Abstract: Provided is a method that includes automatically providing air/oxygen at a pre-selected maximum pressure limit, breath volume and respiratory-rate. The pre-selected maximum pressure limit, breath volume, and respiratory-rate are automatically set as a function of a size of a mask coupled to an air/oxygen supply system. Further provided is a ventilator system that includes a ventilator mask, a ventilator supply system, and a mask conduit. The ventilator mask is configured in a size that will fit upon a selected range of sizes of human faces. The ventilator supply system includes an air/oxygen source and an air/oxygen regulator system configured to regulate air/oxygen flow parameters as a function of the size of the mask. The mask conduit is configured to couple the ventilator supply to the ventilator mask.

Abstract: A surgical hand piece is described that maintains a vacuum pressure within the hand piece at a selected level. A check valve is provided substantially near an inlet of an integrated aspirating pump. The check valve opens to introduce fluid into the hand piece to maintain the vacuum pressure within the hand piece at or above the selected level so as to prevent or substantially reduce post-occlusion flow.

Abstract: A catheter system includes an elongate catheter having a lumen extending at least partially therethrough, and a leading catheter end segment, a guidewire positionable within the lumen of the catheter, and fastening structure supported adjacent the leading catheter end segment. The guidewire and the catheter are adapted for relative movement. The fastening structure is dimensioned to selectively engage the guidewire to secure the guidewire with respect to the leading catheter end segment such that movement of the guidewire causes deflection of the leading end segment with respect to the longitudinal axis.

Abstract: The subject matter disclosed herein relates to systems, methods and/or devices for calibrating sensor data to be used in estimating a blood glucose concentration. A relationship between sensor measurements and reference readings may be used to estimate a relationship between sensor measurements and blood glucose concentration. Such sensor measurements may be weighted according to a decreasing function of uncertainty associated with sensor values.

Abstract: A cage can be positioned around a medical balloon, such as an angioplasty balloon, to assist in a medical procedure. The cage can include a plurality of strips, each extending between a set of rings including first and second rings. As the balloon expands, the first and second rings move closer together and allow the strips to expand outward. The cage may have wedge dissectors on the strips.

Abstract: A technique for treating diabetes that recognizes patient insulin sensitivity is a time-varying physiological parameter. The described techniques for treating diabetes include measuring interstitial fluid glucose concentration, reading insulin delivery data, determining patient insulin sensitivity based on the interstitial fluid glucose concentration and insulin delivery data, and a time-varying physiological parameter, and dispensing an insulin dose from an insulin delivery device based on the determined patient insulin sensitivity.

Abstract: The present invention relates to a fluid injection needle unit having a function of preventing needlestick injury and infection wherein a cover, a needle body and a body are improved in shape, and after the needle body is inserted into a blood vessel of a patient, the cover is coupled to the bottom end periphery of the body and the needle body is detached from the body by means of detachable mounting members, so that a needle and the needle body are inserted unitarily into the cover to prevent the occurrence of the needlestick injury and infection.

Abstract: Hemostasis valves and hemostasis valve assemblies can be coupled to a proximal end of an introducer sheath to prevent blood loss through the proximal end of the introducer sheath. Some hemostasis valve assemblies may include an elastomeric member with a variable-width channel that is designed to form a liquid-tight seal over elongate members of different diameter or a single elongate member of variable diameter.

Abstract: The presently disclosed delivery systems utilize microtools, also referred to as theragrippers, to deliver a drug or other therapeutic agent to targeted tissue. More particularly, the drug delivery system and methods provide a delivery system that is capable of anchoring to a tissue site and then delivering a drug or therapeutic agent to the tissue directly to or in the vicinity of the site over an extended period of time. Any number of theragrippers may be deployed as desired to deliver different doses of a desired drug or therapeutic agent. The theragrippers also can be biodegradable such that they remain in place for an extended period of time and then degrade without adversely affecting the surrounding tissue.

Abstract: There are disclosed devices and methods for protecting a user from a sharp tip of a medical needle. In an embodiment, a device includes a central body portion, a medical needle having a sharp tip, a pair of wings in attachment to the central body portion, and a hook-and-loop fastening system disposed on at least one of the wings, and configured to selectively attach the wings together with the medical needle positioned between the wings so as to protect a user from the sharp tip of the medical needle. In another embodiment, a method includes withdrawing a sharp tip of a medical needle from a patient, closing a pair of wings with the medical needle positioned between the wings, and fastening the wings together with the medical needle positioned between the wings so as to protect a user from the sharp tip of the medical needle.

Abstract: A PIVC includes a catheter adapter having a catheter that extends distally from the catheter adapter, and an introducer needle that inserts through the catheter. The introducer needle has a grip component at a proximal end of the introducer needle. The grip component extends outwardly and distally to form a winged grip adjacent the catheter adapter when the introducer needle is inserted within the catheter. The grip component can be rotatable within the catheter adapter to allow repositioning of the winged grip with respect to the catheter adapter.

Abstract: An enteral feeding connector facilitates an increased flow rate into and through the connector to accommodate feeding fluids requiring higher flow rates for delivery. The connector includes a male connector portion including an inlet, a fluid passage in fluid communication with the inlet, and at least one connector projection at the inlet. The connector projection defines a cross-sectional area of the inlet configured to facilitate delivering feeding fluid requiring higher flow rates through the connector.

Abstract: The invention relates to a breast pump kit comprising a breast pump collection system which is to be replaceable and detachable connected to an electrical driving unit during use. The breast pump collection system comprises a breast shield for placing on a breast of a user, a pump unit, and tubing connecting the breast shield to the pump unit. The pump unit comprises a compartment of a variable volume in fluid connection to the exterior only via the tubing. The pump unit is configured to be detachable combined to the driving unit such that a driving motion of the driving unit acts to alternatingly expand and contract the compartment of the pump unit. In this way the pump unit creates alternating suction and pressure in the breast shield and at the breast of the user when in use. The invention further relates to a breast pump collection system for use in such breast pump kit.

Abstract: The invention is directed to drug delivery device comprising a primary drug delivery assembly (3) with a primary dose dial sleeve (17) and a secondary drug delivery assembly (4) with a secondary drive sleeve (24). For user selection, a selection switch (48) is movable between a first, a second and a third position and a clutch (49) is connected to the selection switch (48) such that movement of the selection switch (48) causes rotation of the clutch (49). A secondary drive sleeve (24) is configured to rotate and to engage the clutch (49), wherein the clutch (49) is configured to transfer rotation to the secondary drive sleeve (24) when the selection switch (48) is moved from the first position into the second position and to disengage from the secondary drive sleeve (24) when the selection switch (48) is moved from the first into the third position.

Abstract: MicroElectroMechanical System (MEMS) devices can be fabricated completely of hydrogel materials. Such hydrogels can include polyethylene glycol with diacrylate functional groups (e.g., PEGDA), which are photopolymerizable in the presence of crosslinkers and photoinitiators. By using PEGDA monomers of different molecular weights and at different percentages, the mechanical properties of the polymerized gels and their respective permeabilities can be tuned. This spatial variation in properties and permeabilities can lead to different functionalities between different portions of the hydrogel MEMS device. Portions of the hydrogel device may be remotely actuated by applying wave energy, for example, a magnetic field, high intensity focused ultrasound, and/or infrared radiation. The remote actuation can allow the device to be actuated in vivo, for example, to allow the device to deliver a drug or other substance at a desired time and/or desired location within a patient.

Abstract: A fluid delivery device comprising a fluid reservoir; a transcutaneous access tool fluidly coupled to the fluid reservoir; and a drive mechanism for driving fluid from the reservoir, the drive mechanism comprising a plunger received in the reservoir; a leadscrew extending from the plunger; a nut threadably engaged with the leadscrew; a drive wheel; and a clutch mechanism coupled to the drive wheel, wherein the clutch mechanism is configured to allow the nut to pass through when disengaged and is configured to grip the nut when engaged such that the drive wheel rotates the nut to advance the drive rod and the plunger into the reservoir.

Abstract: A nasal clip and/or dilator which is U-shaped having protruding wider spherical/spheroid holders at each end of the U is designed to be placed such that each spherical holder is in a nostril. The U-shaped clip can press against the columella and each holder against the septum. Inside each holder is a scented piece, such as a plastic ball or cylinder with aromatic compounds there-in which exit from the surface of the respective scented piece. To facilitate the scent escaping from the scented piece and into the nose, each holder has portals such as around the circumference thereof and/or on opposite sides thereof, transverse to the “U” of the holder.

Abstract: A needleless syringe comprises an enclosing unit for an injection objective substance, a pressurizing unit for the injection objective substance, a discharge unit having a flow passage for allowing the injection objective substance to flow therethrough so that the injection objective substance is discharged from an open end of the flow passage to an injection target area, the open end being formed so that an area thereof is smaller than a flow passage area of the enclosing unit, and a minute pore unit including a minute pore having a flow passage area smaller than the area of the open end of the discharge unit and which is arranged on an outer side of the open end so that the injection objective substance discharged from the open end passes through the minute pore and arrives at a side of the injection target area.