Patents Examined by Jacqueline A. DiRamio
  • Patent number: 7125518
    Abstract: Aerosol particle analyzer (APA) for measuring the amount of analyte in airborne particle is described. The APA uses an analysis liquid. When this analysis liquid is mixed with the particles, an optical property of the analysis liquid (CDAL) varies according to the amount of the analyte in the particles. A charged droplet of the analysis liquid is levitated. Airborne particles are drawn into the instrument and given a charge that is opposite that of the CDAL, and made to flow near the CDAL so that electrostatic forces greatly increase the probability that the CDAL and charged particles will combine. Then the CDAL is ejected into a horizontally oriented linear quadrupole that is in an airtight container, except for a small orifice to let the CDAL enter. The CDAL is levitated in a high humidity environment so that it evaporates slowly, so that there is time for the reaction between the analyte, if any, and the CDAL can take place, and so that the optical property, typically fluorescence, can be measured.
    Type: Grant
    Filed: February 14, 2004
    Date of Patent: October 24, 2006
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventor: Steven Clyde Hill
  • Patent number: 7097981
    Abstract: The present invention relates mainly to reaction vessels, to sets of such vessels for automatic immunological assay apparatuses, to automatic immunological assay apparatuses making use of such sets of vessels, and to a method implementing sets of such vessels. According to the present invention, photometric detection is implemented of the luminescence of a reaction mixture found in a reaction vessel, the apparatus and/or the vessel guaranteeing light-tightness so as to prevent entry of external light falsifying the measurement. Advantageously, sets of vessels in accordance with the present invention are made out of a material that is opaque. The present invention is particularly applicable to detecting the presence of a chemical or a biological substance in a sample. The present invention applies mainly to medical analysis and research.
    Type: Grant
    Filed: September 13, 1999
    Date of Patent: August 29, 2006
    Assignee: Biomerieux
    Inventors: Thierry Gicquel, Edouard Lentwojt
  • Patent number: 7052854
    Abstract: Systems and methods for the ex vivo diagnostic analysis of samples of bodily fluids, including exhaled breath and blood. The present invention uses nanostructure-based assemblies in combination with sensor technology to provide an efficient and accurate means for identifying the presence of a target analyte/biomarker in a sample of bodily fluid. In a preferred embodiment, the nanostructure-based assemblies of the present invention include detecting means such as RNA oligonucleotide chains or “apparatus” and releasable surrogate markers such as DMSO.
    Type: Grant
    Filed: October 2, 2003
    Date of Patent: May 30, 2006
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Richard J. Melker, Ronald L. Hayes, Ka-Wang Kevin Wang, Donn Michael Dennis