Patents Examined by James D Ponton
  • Patent number: 12268849
    Abstract: A syringe finger ring and finger ring inserts, that in various embodiments, provides or connects to a syringe that comprises a syringe body capable of having a volume of material therein and a plunger disposed to enter the syringe body and dispense material from the syringe body by movement of plunger, and a novel a finger ring related structures having an open area and connected, by various structures, to the plunger adapted to receive a finger within the finger ring open area, including a spacer of various embodiments inserted within the open area to selectively reduce the open area and provide more controllable engagement of the syringe plunger by the operator finger in distal and proximal strokes.
    Type: Grant
    Filed: September 1, 2023
    Date of Patent: April 8, 2025
    Assignee: Alger & Klemer, LLC
    Inventors: Gennady I Kleyman, Alexander Merson
  • Patent number: 12268854
    Abstract: A syringe device for ejecting a dose of a medicament, the syringe device comprising: a dose limiting mechanism arranged to interact with a dose ejecting mechanism to prevent ejection of a dose exceeding a set dose, and a safety mechanism, which is arranged such with respect to the dose ejecting mechanism that, if the dose limiting mechanism fails, the safety mechanism prevents ejection of a dose exceeding the set dose.
    Type: Grant
    Filed: July 22, 2021
    Date of Patent: April 8, 2025
    Assignee: Novo Nordisk A/S
    Inventors: Jacob Eiland, Christian Peter Enggaard, Claus Schmidt Moeller, Tom Hede Markussen
  • Patent number: 12268832
    Abstract: Self-righting articles, such as self-righting capsules for administration to a subject, are generally provided. In some embodiments, the self-righting article may be configured such that the article may orient itself relative to a surface. In some embodiments, the self-righting article may have a particular shape and/or distribution of density (or mass) which, for example, enables the self-righting behavior of the article. In some embodiments, the self-righting article may comprise a tissue interfacing component and/or a pharmaceutical agent. In some cases, upon contact of the tissue with the tissue engaging surface of the article, the self-righting article may be configured to release one or more tissue interfacing components. In some cases, the tissue interfacing component may comprise and/or be associated with the pharmaceutical agent.
    Type: Grant
    Filed: December 30, 2022
    Date of Patent: April 8, 2025
    Assignees: Massachusetts Institute of Technology, The Brigham and Women's Hospital, Inc.
    Inventors: Robert S. Langer, Carlo Giovanni Traverso, Alex G. Abramson, Michael Williams, Jacob Wainer
  • Patent number: 12268833
    Abstract: A microarray receptacle which has a first side and a second side. Furthermore, the microarray receptacle includes a carrier structure for connecting the microarray receptacle to an application point. To the carrier structure there is connected a carrier surface which in turn is connected to a microarray. An articulation device is arranged between the carrier surface and the carrier structure, the articulation device making possible movement of the microarray connected to the carrier surface relative to the carrier structure along the extent of the microarray. Further, a microarray receptacle cluster with a plurality of such microarray receptacles.
    Type: Grant
    Filed: November 26, 2019
    Date of Patent: April 8, 2025
    Assignee: LTS Lohmann Therapie-Systeme AG
    Inventors: Michael Kulik, Thorsten Fehr, Stefan Erlhofer
  • Patent number: 12263326
    Abstract: A fluid delivery system and method for determining whether the correct fluid is being drawn into and/or dispensed from a syringe. The system includes a syringe, a fluid injector for drawing fluid into and dispensing fluid from the syringe, one or more sensors adapted to measure a force required to draw the fluid into and/or dispense the fluid from the syringe, a processor in communication with the one or more sensors, and a non-transitory, computer-readable storage medium in operable communication with the processor. The computer-readable storage medium contains one or more programming instructions that, when executed, cause the processor to receive from the one or more sensors one or more measurements of the force required to draw the fluid into and/or dispense the fluid from the syringe and determine from the one or more measurements whether a correct fluid is being drawn into and/or dispensed from the syringe.
    Type: Grant
    Filed: November 13, 2017
    Date of Patent: April 1, 2025
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Arthur Uber, III, Michael Spohn, David Griffiths, Ralph Schriver
  • Patent number: 12246153
    Abstract: The present disclosure relates to implantable encapsulation devices for housing a biological moiety or a therapeutic device that contains a biological moiety. Particularly, aspects of the present disclosure are directed to an implantable apparatus that includes a distal end, a proximal end, a manifold including at least one access port positioned either at the distal end or the proximal end, and a plurality of containment tubes affixed to the manifold and in fluid communication with the at least one access port. Additionally, the encapsulation device may contain a flush port and a tube that are fluidly connected to the manifold. The containment tubes may contain therein a biological moiety (e.g., cells) or a therapeutic device (e.g. a cell encapsulation member).
    Type: Grant
    Filed: May 19, 2021
    Date of Patent: March 11, 2025
    Assignee: W.L. Gore & Associates, Inc.
    Inventors: Edward H. Cully, Edward Gunzel, Keith Knisley, Greg Rusch, Lauren Zambotti
  • Patent number: 12239807
    Abstract: Intravesical drug delivery devices are provided which may include an elongated body formed of a matrix system of a drug dispersed in a silicone, wherein the elongated body has a first end, an opposed second end, and an intermediate portion between the first and second ends, and wherein the silicone of the matrix system is cured to bias the elongated body in a coiled retention shape, such that the device is elastically deformable between a relatively straightened shape suited for insertion of the device through a urethra and into the urinary bladder of a patient and the coiled retention shape which is suited to retain the device within the urinary bladder.
    Type: Grant
    Filed: August 10, 2020
    Date of Patent: March 4, 2025
    Assignee: TARIS Biomedical LLC
    Inventors: Heejin Lee, Karen Daniel
  • Patent number: 12236800
    Abstract: An injection device and an injection device trainer for training a user to use an injection device. Each one of the injection device and the injection device trainer can include: a body portion; an actuator positioned towards a proximal end of the body portion, the actuator moveable from a proximal position to a distal position; a shield positioned towards a distal end of the body portion, the shield moveable between: an initial position; a retracted position that is more proximal relative to the body portion than the initial position; and an extended position that is more distal relative to the body portion than the initial position; and a locking member rotatable between a first orientation in which the locking member resists movement of the actuator from the proximal position to the distal position; and a second orientation in which the locking member permits the actuator to move from the proximal position to the distal position.
    Type: Grant
    Filed: September 27, 2019
    Date of Patent: February 25, 2025
    Assignee: Janssen Pharmaceuticals, Inc.
    Inventor: Hung Mach
  • Patent number: 12233235
    Abstract: A patch-sized fluid delivery device may include a reusable portion and a disposable portion. The disposable portion may include components that come into contact with the fluid, while the reusable portion may include only components that do not come into contact with the fluid. Redundant systems, such as redundant controllers, power sources, motor actuators, and alarms, may be provided. Alternatively or additionally, certain components can be multi-functional, such a microphones and loudspeakers that may be used for both acoustic volume sensing and for other functions and a coil that may be used as both an inductive coupler for a battery recharger and an antenna for a wireless transceiver. Various types of network interfaces may be provided in order to allow for remote control and monitoring of the device.
    Type: Grant
    Filed: May 4, 2020
    Date of Patent: February 25, 2025
    Assignee: DEKA Products Limited Partnership
    Inventors: Dean Kamen, Larry B. Gray
  • Patent number: 12220556
    Abstract: A bidirectional electroosmotic pump may be provided. The bidirectional electroosmotic pump may be made of materials that are biocompatible and non-ferrous. The bidirectional electroosmotic pump may be part of an implantable medical device for the purpose of medicine delivery. The bidirectional electroosmotic pump may contain a working fluid and may facilitate the delivery of a separate payload fluid. In an exemplary embodiment, the bidirectional pump may contain bellows which may allow the pump to deliver the payload fluid through a series of valves and/or catheters. In another embodiment the bidirectional electroosmotic pump may contain a pump sensing mechanism to monitor the state of the pump.
    Type: Grant
    Filed: October 6, 2023
    Date of Patent: February 11, 2025
    Assignee: CraniUS LLC
    Inventors: John Cai, Nathan Scott, Charles Watkins, Ashley Hinga, Elayna Williams, Charlotte Quinn, Mark Gonzales, Owen Friesen, Conner Delahanty
  • Patent number: 12220564
    Abstract: An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.
    Type: Grant
    Filed: June 26, 2024
    Date of Patent: February 11, 2025
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Simon Francis Brereton, Thomas Kemp, Rosie Burnell, Matthew Ekman
  • Patent number: 12220505
    Abstract: A method of monitoring an operation of an electric breast pump (100) using an external smart device (200) is provided. The external smart device (200) comprises a vibration detection unit (210) for detecting vibrations emitted from the breast pump (100). The detected vibrations are analyzed to extract information regarding the operation of the electric breast pump (100). The information comprises at least one of mode of operation and settings of the modes of operation of the breast pump (100). The extracted information can be outputted.
    Type: Grant
    Filed: May 20, 2019
    Date of Patent: February 11, 2025
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Yannyk Parulian Julian Bourquin, Jonathan Alambra Palero, Lili-Marjan Boelens-Brockhuis, Okke Ouweltjes, Albertus Cornelis Den Brinker, Lucja Elzbieta Segaar
  • Patent number: 12220560
    Abstract: An exemplary embodiment of an injector includes a trigger mechanism, an energy source, and a user-operable firing-initiation member. The trigger mechanism can include a floating trigger member having a retaining portion, a ram assembly having a ram configured to pressurize a medicament container for expelling a medicament therefrom, the ram assembly further having a floating trigger engagement member configured to engage the retaining portion of the floating trigger member when the floating trigger member is in a pre-firing condition. The energy source can be associated with the ram for powering the ram to expel the medicament, and the user-operable firing-initiation member can be operable for causing an axial rotation of the floating trigger member from the pre-firing condition to a firing condition in which the floating trigger engagement member is released from the retaining portion to allow the energy source to fire the ram.
    Type: Grant
    Filed: August 11, 2022
    Date of Patent: February 11, 2025
    Assignee: Antares Pharma, Inc.
    Inventors: Thomas Kramer, Matthew H. Rust, Paul M. Goudreau, Peter A Hoeft, Julius C. Sund, Peter L. Sadowski, Michael Travanty, Patrick Madsen
  • Patent number: 12220567
    Abstract: An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.
    Type: Grant
    Filed: January 16, 2024
    Date of Patent: February 11, 2025
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Simon Francis Brereton, Thomas Kemp, Rosie Burnell, Matthew Ekman
  • Patent number: 12220565
    Abstract: A dose monitoring system for mounting on an injection pen having a body and a dose setting wheel defined at the end of the body. The dose monitoring system includes a magnet configured to be attached to an outer surface of the dose setting wheel, a housing configured to be attached to an outer surface of the body of the injection pen, the housing includes an integrated control unit and at least one magnetometer in electrical connection with the integrated control unit, the integrated control unit, when the housing is mounted on the injection pen, being configured to register at least one magnetic field sensed by the at least one magnetometer when the magnet co-rotates with the dose setting wheel during setting of a dose by a user on the injection pen, the integrated control unit being further configured, when the housing is mounted on the injection pen, to calculate a dose set by the user of the injection pen from the at least one magnetic field registered with the integrated control unit.
    Type: Grant
    Filed: September 21, 2022
    Date of Patent: February 11, 2025
    Inventors: Alain Marcoz, Emmanuel Jez, Sylvain Diogo, Patrice Gourbet, Alexandre Pereira, Mathieu Pollard, Kevin Gillet
  • Patent number: 12220563
    Abstract: An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.
    Type: Grant
    Filed: March 20, 2024
    Date of Patent: February 11, 2025
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Simon Francis Brereton, Thomas Kemp, Rosie Burnell, Matthew Ekman
  • Patent number: 12214176
    Abstract: An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.
    Type: Grant
    Filed: June 27, 2024
    Date of Patent: February 4, 2025
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Simon Francis Brereton, Thomas Kemp, Rosie Burnell, Matthew Ekman
  • Patent number: 12214157
    Abstract: A fluid interface device for delivering fluid to and/or withdrawing fluid from a patient, the device comprises a peripheral base element (2) and a fluid transmission element (4) sealingly connected to the base element and forming a central portion of the device. The fluid transmission element comprises a front platelet (6) with a primary face (8) and a secondary face (10) opposed thereto, the primary face being in contact with a patient's body fluid region (12) when the device is implanted in the patient, the fluid transmission element further comprising a counterplate (14) sealingly stacked against the secondary face of the front platelet and forming a buffer volume (16) therebetween. The front platelet comprises at least one array of microchannels (18) defining a fluid passage between the buffer volume and the primary face, the microchannels having an opening of 0.2 to 10 ?m. The counterplate has at least one fluid port (20; 20a, 20b) for fluid delivery to and/or fluid withdrawal from the buffer volume.
    Type: Grant
    Filed: September 3, 2021
    Date of Patent: February 4, 2025
    Assignee: SeraIP AG
    Inventor: Carlo Andretta
  • Patent number: 12214171
    Abstract: An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.
    Type: Grant
    Filed: June 27, 2024
    Date of Patent: February 4, 2025
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Simon Francis Brereton, Thomas Kemp, Rosie Burnell, Matthew Ekman
  • Patent number: 12214170
    Abstract: An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.
    Type: Grant
    Filed: June 26, 2024
    Date of Patent: February 4, 2025
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Simon Francis Brereton, Thomas Kemp, Rosie Burnell, Matthew Ekman