Abstract: Devices and methods for treating or repairing a tissue or organ defect or injury are provided. The devices can include tissue scaffolds produced from acellular tissue matrices and polymers, which have a stable three-dimensional shape and elicit a limited immunologic or inflammatory response.
Type:
Grant
Filed:
March 24, 2011
Date of Patent:
July 22, 2014
Assignee:
LifeCell Corporation
Inventors:
Rick Owens, Wendell Sun, Mike Liu, Yong Mao
Abstract: A knee joint prosthesis can include a tibial component that can have a tibial tray. The tibial tray can include a platform-like tray that defines a superior surface and an inferior surface. The platform-like tray can have a tray perimeter and a raised wall formed on the inferior surface. The raised wall can be offset inboard relative to the tray perimeter. Porous material can be disposed on the inferior surface of the platform-like tray at a location generally between the raised wall and the tray perimeter.
Abstract: Implantable frames for use in body passages are provided herein. The implantable frames can include a plurality of hoop members joined by a plurality of longitudinal connecting members to form a tubular frame defining a cylindrical lumen. The plurality of longitudinal connecting members may include first and second longitudinal connecting members joining a first hoop member to a second hoop member such that the first and second longitudinal connecting members extend across an entire space separating the first and second hoop members.
Type:
Grant
Filed:
June 24, 2013
Date of Patent:
July 8, 2014
Assignee:
Cook Medical Technologies LLC
Inventors:
Darin G. Schaeffer, Jacob A. Flagle, Michael L. Garrison, Brian C. Case, Andrew K. Hoffa
Abstract: Hard-tissue implants are provided that include a bulk implant, a face, pillars, and slots. The pillars are for implantation into a hard tissue. The slots are to be occupied by the hard tissue. The hard-tissue implant has a Young's modulus of elasticity of at least 10 GPa, has a ratio of the sum of (i) the volumes of the slots to (ii) the sum of the volumes of the pillars and the volumes of the slots of 0.40:1 to 0.90:1, does not comprise any part that is hollow, and does not comprise any non-pillar part extending to or beyond the distal ends of any of the pillars. Methods of making and using hard-tissue implants are also provided.
Abstract: This disclosure is directed to a resilient interpositional arthroplasty implant for application into a knee joint to pad cartilage defects, cushion a joint, and replace or restore the articular surface, which may preserve joint integrity, reduce pain and improve function. The implant may endure variable joint compressive and shear forces and cyclic loads. The implant may repair, reconstruct, and regenerate joint anatomy, and thereby improve upon joint replacement alternatives. Rather than using periosteal harvesting for cell containment in joint resurfacing, the walls of this invention may capture, distribute and hold living cells until aggregation and hyaline cartilage regrowth occurs. The implant may be deployed into debrided joint spaces, molding and conforming to surrounding structures with sufficient stability to avoid extrusion or dislocation.
Abstract: A medical device for canalization of a tissue comprises a radially expandable and crimpable or collapsible substantially tubular member that has a rear end, a front end, and a pattern of struts or a mesh of wires arranged in-between the rear end and the front end, arranged around an interior of the device. The tubular member has extensions, which are arranged towards the interior of the device in a first state of the device, and towards an exterior of the medical device in a second state of the device, wherein the second state of the medical device is the tubular member turned inside out. During storage, the device is restrained in a delivery catheter in the second state. During delivery the device turns outside in and digs into the tissue to create a channel therein, thus preventing or fixating debris or other matter to spread from the channel.
Abstract: A prosthetic heart valve includes a radially expandable stent and a plurality of leaflets. Each leaflet includes a coaptation portion, an arcuate edge, and a belly. The coaptation portion is movable relative to respective coaptation portions of the other leaflets. The arcuate edge has a first end and a second end and is coupled to the stent. The belly extends from the arcuate edge to an axis defined by the first and second ends of the arcuate edge, wherein the ratio of the surface area of the belly to the outer cross-sectional area of the expanded stent is about 0.09 to about 0.16.
Abstract: A method for reducing regurgitation in a mitral valve using a blood flow controlling apparatus. The blood flow controlling apparatus comprises an anchoring means, preferably arranged to anchor the apparatus to a wall of the left ventricle. The blood flow controlling apparatus further comprises a valve means configured to expand in a direction transverse to blood flow. The valve means is preferably positioned within a native mitral valve and expands for making contact with the mitral valve leaflets during ventricular systole, thereby preventing blood from regurgitating back through the mitral valve into the left atrium. When blood flows from the left atrium to the left ventricle during ventricular diastole, the valve means collapses for allowing blood to pass freely through the mitral valve.
Abstract: An orthopaedic knee prosthesis is provided including a tibial baseplate component having a distal, bone-contacting surface with one or more fixation structures extending distally therefrom, in which the fixation structures are asymmetrically arranged within the baseplate periphery.
Type:
Grant
Filed:
August 23, 2012
Date of Patent:
June 24, 2014
Assignee:
Zimmer, Inc.
Inventors:
Mary S. S. Wentorf, Calie B. Grey, Shaun R. Cronin
Abstract: An orthopaedic prosthesis includes a curved outer surface configured to abut a patient's bone when the orthopaedic prosthesis is implanted therein. The outer surface may or may not be electrically conductive. A channel is defined in the outer surface in which one or more electrical conductors are positioned. A switch is positioned at a first location on the outer surface and is configured to establish an electrical connection between the electrical conductor and the outer surface (e.g., an electrical trace) and/or another electrical conductor when the first location of the outer surface is pressed against the patient's bone. The switch may be embodied as an end of the electrical conductor or a more complex switch such as a push-button type switch.
Abstract: Stents and methods of using stents are provided. Stents of the invention provide external support structure for a blood vessel segment disposed within, wherein the stents are capable of resilient radial expansion in a manner mimicking the compliance properties of an artery. The stent may be formed of a knitted or braided mesh formed so as to provide the needed compliance properties. A venous graft with the stent and a vein segment disposed within is provided, wherein graft is capable of mimicking the compliance properties of an artery. Methods of selecting stents for downsizing and methods of using the stents of the invention in downsizing and smoothening are provided. Methods of replacing a section of an artery with a venous graft including a stent of the invention are provided. Methods of reducing intimal hyperplasia in implanted vein segment in a venous graft using stents of the invention are provided.
Type:
Grant
Filed:
January 21, 2013
Date of Patent:
June 10, 2014
Assignee:
Kips Bay Medical, Inc.
Inventors:
Peter P. Zilla, Nasser Rafiee, Deon Bezuidenhout, Thomas Franz, Mark Yeoman, Helmut Bowles, Nareak Douk, Michael C. Wolf, Paul Human
Abstract: Embodiments relate to a joint replacement device, including a fixed socket including an inner surface and an outer surface supporting a ball, an articulating socket including an inner surface and an outer surface the inner surface in contact with the ball and a stem component attached to the outer surface of the articulating socket. The inner surface of the articulating socket articulates with the ball and the outer surface of the articulating socket can articulate with the inner surface of the fixed socket.
Abstract: A method of treating a diseased cardiac valve can include implanting a valve prosthesis by compressing the valve prosthesis to a compressed state for delivery and expanding the valve prosthesis to an expanded state for deployment. The valve prosthesis can include a valve fixation device having a plurality of struts, a first circumferential row of cells coupled to the struts, and a second circumferential row of cells coupled to the struts. The struts are substantially rigid such that the struts do not change dimensions between the compressed state and the expanded state. The valve prosthesis can also include a plurality of leaflets and a plurality of commissures. The valve is coupled to the valve fixation device such that the commissures are radially aligned with respective struts of the plurality of struts.
Type:
Grant
Filed:
September 14, 2012
Date of Patent:
June 3, 2014
Assignee:
Medtronic, Inc.
Inventors:
Gregory H. Lambrecht, John Liddicoat, Robert Kevin Moore
Abstract: A vascular endoprosthesis (1) is disclosed which is capable of being arranged internally to the aortic arch (O), comprising: a tubular main body (2), to be housed in the internal lumen of the aortic arch (O); three tubular secondary bodies (3, 4, 5), originating from the main body (2) and to be housed in the right carotid artery (R), in the left carotid artery (L) and in the subclavian artery (S); and stent-type engagement means (10, 11, 13, 14, 15), intended to hold a longitudinal end portion (21, 22, 31, 41, 51) of the main and secondary bodies onto the internal wall of the respective vessel (FIG. 5).
Abstract: Tibial inserts and tibial femoral systems are provided for improved knee reconstruction systems. External rotation of a knee joint implant is enhanced by modifications to the post, providing a recess that allows clearance of the post against the corners of a box wall within the femoral component. The rotation provides for a more natural knee joint motion of the implant. The depth, size, and location of the post relief may be modified for certain applications to provide both improved rotational motion and constraint against undesirable motion of the knee.
Abstract: A micro-alloyed porous metal is disclosed having an optimized chemical composition to achieve targeted mechanical properties for use as an orthopaedic implant and a cell/soft tissue receptor. The porous metal may achieve a targeted compressive strength and a targeted ductility, for example. These targeted mechanical properties may allow the porous metal to be densified to a low relative density.
Abstract: Systems and methods for providing deeper knee flexion capabilities. In some instances, such systems and methods include an asymmetrical femoral component that includes a femoral prosthesis that is configured to attach to a distal portion of a femur. In some such instances, the prosthesis includes a medial condyle and a lateral condyle, wherein a medial-lateral width of an articulation surface of the lateral condyle is approximately 75% or less of a medial-lateral width of an articulation surface of the medial condyle. Other implementations are also discussed.
Abstract: Systems and methods for providing deeper knee flexion capabilities, more physiologic load bearing and improved patellar tracking for knee prosthesis patients. Such systems and methods include a tibial component for replacing at least part of a proximal portion of a tibia. In some cases, the tibial component includes an articulation feature that forms a projection that projects from a posterior portion of at least one of a medial articulation surface and a lateral articulation surface of the tibial component. In some cases, the articulation feature is contained within an area of the tibial component that is selected from a lateral portion which is lateral to a medial-most portion of an intercondylar surface, and a medial portion, which is medial to a lateral-most portion of the intercondylar surface, and wherein the intercondylar surface is disposed on an object selected from the tibial component and the proximal portion of the tibia.
Abstract: Systems and methods for providing deeper knee flexion capabilities. In some instances, such systems and methods include a knee prosthesis that includes a femoral component for replacing at least a portion of a distal end of a femur. In some cases, the femoral component has a posterior condyle that is configured to articulate against a tibial articular surface. In such cases, an articular surface at a proximal portion of the posterior condyle is sized and shaped to extend at least half of an antero-posterior distance between a most posterior portion of the posterior condyle and a plane that is a continuation of a distal one fourth to one third of a posterior cortex of a femoral shaft of the femur. Other implementations are also discussed.
Abstract: Systems and methods for providing deeper knee flexion capabilities. In some instances, such systems and methods include a tibial component that has an asymmetrical articular plateau that includes a medial tibial condylar surface and a lateral tibial condylar surface. In some cases, at least one of the medial condylar surface and the lateral condylar surface includes a concave articulation surface having a lowest point that disposed from a posterior edge of the tibial component by between about 18% and less than about 35% of a total anteroposterior dimension of the tibial component. Other implementations are also discussed.