Abstract: Systems and methods for providing deeper knee flexion capabilities. In some instances, such systems and methods include a modular component, wherein the modular component is configured to attach to a femoral component, and wherein the femoral component is configured to attach to a distal portion of a femur. In some cases, the modular component includes an articular surface that is configured to increase a surface area of an articulation surface of a proximal portion of a posterior condyle of the femoral component. Other implementations are also discussed.

Abstract: A multiple-component expandable endoluminal system for treating a lesion at a bifurcation including a self expandable tubular root member having a side-looking engagement aperture, a self expandable tubular trunk member comprising a substantially blood impervious polymeric liner secured therealong; both having a radially compressed state adapted for percutaneous intraluminal delivery and a radially expanded state adapted for endoluminal support.

Abstract: A variety of options for for fracture fixation after total hip arthroplasty or total knee arthroplasty. The ability to pre-engineer fracture fixation contingent solutions into femoral or tibial components provides a distinct clinical advantage in the planning and execution for periprosthetic fracture fixation. Methods and apparatus include targeting devices allowing for intimate association of fixed angle locking screws in pre-drilled holes in an existing prosthetic, femoral nail, or other components including additional fixation components. Such apparatus and methods further include alignment devices and other components to allow for ease of repair of periprosthetic fractures utilizing the pre-engineered solutions.

Abstract: A joint assembly incorporated into a reconditioned end surface established between upper and opposing lower bones. At least one first component is anchored into a first of the reconditioned bone end surfaces and exhibits a rotatably supported wheel. A second component is anchored into a second opposing reconditioned bone end surfaces and exhibits a second exposed support surface in contact with the rotatably supported wheel. The first component includes a supporting well anchored into the reconditioned bone end surface for supporting the wheel in rotatable fashion. A laterally inserting pin displaces relative to a side of the wheel well and into an interior thereof and includes a central axial through hole which receives the pin for supporting the shaft.

Abstract: A device for unicompartmental arthroplasty of the knee. The device permits arthroplasty of the medial and/or lateral tibial condyle, and allows for securing of the device without the use of bone cement. Such a device comprises a baseplate, the baseplate comprising a first surface configured to be secured to a surgically prepared medial (or lateral) compartment of a proximal end of a patient's tibia, and an opposing second surface configured to replicate a medial (or lateral) tibial condyle; a flange adjacent the baseplate, the flange shaped to interface with a surgically prepared anterior surface of the proximal end of the patient's tibia, the flange comprising an orifice therethrough; and at least one anchor protruding from the first surface, the at least one anchor arranged to coincide with at least one corresponding surgically prepared void in the patient's tibia.

Abstract: Disclosed herein are methods and devices for repairing articular surfaces in a knee joint. The articular surface repairs are customizable or highly selectable for each patient and geared toward providing optimal fit and function. Kits are also provided to enable customized repairs to be performed.

Abstract: An orthopaedic knee prosthesis includes a tibial bearing component with articular features which operate to protect adjacent soft tissues of the natural knee, promote and/or accommodate desired articulation with an abutting femoral component, and facilitate expedient and effective implantation by a surgeon.

Abstract: Methods and apparatus of providing a joint replacement parts with a pharmaceutical delivery system is provided. The pharmaceutical delivery system is placed within the joint replacement parts to provide, over a period of time, sustained release of a controlled concentration of pharmaceuticals within the joint space of the joint replacement and to produce a local or systemic physiological of pharmacological effect.

Abstract: An artificial mitral valve is anchored in the left atrium by placing the valve between the annulus of the natural mitral valve and an artificial annulus. The artificial annulus is formed by inserting a tool into the coronary sinus, and adjusting the tool to force the wall of the left atrium to form an annulus above the artificial valve, this locking it in place and forming a hemostatic seal.

Abstract: An endoluminal prosthesis system deployable in a region of a patient's vasculature having one or more branch vessels, having a main graft body having a first opening in a wall portion of the main graft body and a pre-loaded guidewire positioned inside the main graft body and advanced through the first opening. One or more branch grafts can be attached to the main graft body to cover one or more openings in the main graft body.

Abstract: A seal for preventing a bodily fluid from penetrating an orthopedic implant comprising a tapered section adapted to conformingly mate to a stem of a first implant component, and a collar section extending from and circumferentially surrounding a portion of the tapered section, the collar section adapted to mate to a base of a second implant component such that the tapered section and collar section define an opening therethrough configured to receive the first implant component.

Abstract: A prosthetic assembly and a method of assembling same. The prosthetic assembly includes a base component with at least one engagement surface. A pyrolytic carbon component includes at least one engagement surface. The pyrolytic carbon component is elastically deformed to mechanically interlock with the engagement surface on the base component. The pyrolytic carbon component retains at least a portion of the deformation stress created during coupling with the base component.

Abstract: This invention is a modular intraluminal tubular stent system for deployment in the venous system. One of the stents in the system includes a reinforced terminal end portion, such as a helical coil, to provide additional expansive force to maintain the initial deployed location of the stent. The coil may be interwoven into the wall of the stent, or a separate structure deployed separately.

Abstract: A graft device comprising a layer of synthetic non-metallic material having a first surface and a second surface spaced apart from the first surface. The device further, includes a radiopaque marker at least partially embedded in the layer.

Abstract: A biologic diarthrodial joint includes an artificial subchondral bone shaped in the form of a joint replacement member and formed of an artificial fiber material. The artificial fiber material includes synthetic fibers formed in a fibrous network with the synthetic fibers arranged in multiple orientations. The artificial subchondral bone includes a polymer receiving component. An artificial cartilage polymer is cooperable with the artificial subchondral bone and engages the polymer receiving component. The artificial cartilage polymer has physical properties similar to that of native articular cartilage.

Abstract: A prosthesis humeral implant has a stem including a coupling element at a proximal end thereof and a head having a coupling element at a distal portion thereof for coupling to the stem portion coupling element. The head has a bearing surface portion for articulating on a prosthetic glenoid and a base portion. A soft tissue attachment element has an L-shape with a mounting flange portion of the L-shape extending and clamped between the bearing portion and base portion. The soft tissue attachment portion has a portion extending proximally from the mounting flange portion. The soft tissue attachment element mounting portion is captured between the head bearing portion and base portion preferably by clamping or being permanently attached to one of the base or bearing portions during manufacture.

Abstract: An implantable prosthetic valve assembly having a support stent, or frame, having circumferential struts with multiple bends forming obtuse angles when the valve assembly is expanded to its functional size. The frame can be manufactured with one or more of the circumferential struts in a partially collapsed state and a flexible valve member can be mounted to the partially collapsed frame. The partially collapsed struts can be formed with multiple bends having angles selected to facilitate crimping of the frame to a profile suitable for percutaneous delivery. When the frame is expanded, the bends can expand to form obtuse angles, thereby enhancing the rigidity of the frame to better resist closing forces exerted on the valve assembly.

Abstract: A locking system to be fitted on a joint device (10) is equipped with means of control of the relative range of motion (R.O.M.) between two rods or uprights (11, 12) connected to it; said joint consists of a pair of plates (13, 14) connected to each other by means of rivets (15) and to the rods or uprights (11, 12) protruding from the joint. This locking system comprises at least one locking device consisting of a stop member (16) which is inserted between a rod (11) and the plate (13) connected to a fixed central element of the joint. Said stop member is activated to move from a retracted position to an inserted position in the joint, at right angles in respect of the plane of the plate (13), by means of a cursor element (18) sliding on a slide (19) positioned in the upper part of a bridge element (20), said cursor element comprising a sloping surface (17) which causes the movement of the stop member (16) from a retracted to an inserted position.

Abstract: The present invention relates to an anchor configured for minimally-invasive implantation and sized to remain securely positioned within at least a portion of the gastrointestinal tract of an animal. The anchor includes a radial spring formed from an elongated resilient member shaped into an annular wave pattern about a central axis. The anchor defines a central lumen and provides an outward radial force, while allowing for substantial flexure about its perimeter. The anchor is generally removable, but can include fasteners, such as barbs, to further secure it to the surrounding anatomy. In some embodiments, the anchor includes a connector coupling a fixed portion to a removable portion. Further, the anchor can be used to secure a medical device within the body, such as a flexible sleeve within the intestine.

Abstract: Apparatus for regulating blood flow of a subject is provided, the apparatus comprising a prosthetic valve that comprises a tubular element, shaped to define a lumen therethrough; and a valve member, configured to be coupled to the tubular element and to be disposed within the lumen. The prosthetic valve has (1) a compressed configuration in which the lumen has a compressed width, the valve member is generally cylindrical, and the prosthetic valve is configured to be percutaneously delivered into the subject, and (2) an expanded configuration in which the lumen has an expanded width that is greater than the compressed width, and the valve member is generally disc-shaped, is coupled to the tubular element, and is disposed within the lumen. Other embodiments are also described.